Una Health Ltd
Document Control
Author: E. C. Hamer
UH-POC-TM-2 Revision 1
Date of Issue 26.04.10
Photocopied versions & handwritten amendments of this document are not controlled
Page 13 of 54
Printed 27 April 2010
Uric acid
Uric acid is the end product of purine metabolism. A large proportion of the purines in
food will be reused, while the rest is degraded to uric acid. Up to 70 - 80 % of uric
acid is excreted via the kidneys, and an additional 20 - 30 % leaves the body via the
intestines.
Hyperuricaemia is the hallmark of gout. In most cases hyperuricaemia is due to a
disorder of uric acid excretion by the kidneys. In rare cases, it is caused by an
enzyme defect resulting in an increase of purine degradation and overproduction of
uric acid. Determination of the uric acid concentration in the blood allows you to
evaluate the patient's risk, to diagnose and to monitor the therapy of gout or kidney
stones.
PRINCIPLES OF METHOD
The Reflotron®
®
Plus is an in vitro diagnostic device designed for the quantitative
determination of clinical chemistry parameters using Reflotron®
®
Test reagent strips.
It works on the principle of reflectance photometry and ensures rapid and reliable
results while being easy to use.
An incorporated plasma separating system in the Test strips make it possible to use
whole blood (capillary or venous) aswell as plasma and serum,
A reflectance measurement is recorded based on the colour change on the test
strip:
Measuring range >>20 – 1250U/L
Measuring Range >> 29 – 860U/L
