SP Scientific Freezemobile Series, Operator'S Manual, Page: 31 / 54

VirTis Freezemobile 25L and 35L Basic Operation
Rev 005, 02/12 21
© SP Scientific 2012
Product Dryness End Point
You can clearly observe drying rates during manifold drying since the glassware and
product are completely visible. However, since the glassware is exposed to room
temperature, environmental moisture may condense and freeze on the cold outer
surface of the flask. This is normal.
As the product ice inside the glassware gradually sublimes, the frost on the outside of
the glassware slowly recedes and eventually disappears. By this point, approximately
98% of product moisture has been removed. You can assume drying is complete (
i.e.,
<1% moisture content) when the exterior of the glassware is at room temperature.
Stoppering (Optional)
The stoppering option applies pressure to partially-inserted stoppers, forcing them into
the vials while sealing the product under system vacuum. Stoppering can be operated
at atmospheric pressure or under vacuum. Stoppering must be performed with evenly
distributed vials of equal height to ensure uniform stoppering force distribution and
prevent vial shifting.
Stopper vials only after:

The product is fully dried.

The vacuum system is turned off.

The shelf heat control is disabled.
Note: SP Scientific recommends performing a test run to ensure that you are familiar with the
stoppering process before stoppering vials of product.
The optional stoppering system includes a manual stoppering mechanism, and comes
with either heated or unheated shelves. For more information, see Chapter 5: Optional
Components.