NuAire LabGard NU-581-400, Operation And Maintenance Manual

Page: 5 / 107

OM0302
Rev 2/December 2020 Page 5 of 107
LabGard® ES HD Energy Saver
Class II, Type A2 Laminar Flow
Biosafety Cabinet
Models
NU-581-400/500/600
Manufactured by:
Nuaire, Inc. - Plymouth, Minnesota, U.S.A.
1.0 General Information
1.1 Description
The LabGard® ES HD Model NU-581 Laminar Flow Biosafety Cabinet (LFBSC) is a bench/table top model, optionally available
with a base support stand, for operation as a console model. The LabGard® ES model NU-581 utilizes an Energy Saver DC
ECM motor optimally determined forward curved fan for each model size/width to maximize both energy efficiency and
filter loading capacity. The Energy Saver ECM motor is controlled airflow setpoints via a solid-state DC motor controller
with digital dual thermistor airflow sensors that provide an automatic compensation (constant volume control) for both
filter loading and line voltage variances.
The Laminar Flow Biosafety Cabinet, (LFBSC) is a product resulting from the development of the "laminar flow" principle
(see Airflow Schematic) and the application of environmental controls as required in the field of biological research or
(Hazardous Drug) chemical containment. The LFBSC, when used with proper technique, is an effective primary engineering
control in obtaining the optimum product quality while reducing the potential for exposure of both product and personnel
to airborne biological or particulate chemical agents in low to moderate risk-hazard research and drug preparation or
product operations, as prescribed by the Center for Disease Control (CDC) Atlanta, Georgia.
The NU-581 bench LFBSC meets the requirements of a Class II, since the cabinet conforms to the following requirements:
1. Maintains a minimum inflow velocity of 100 LFPM (.51mps) through the work access opening.
2. Has HEPA filtered downflow air that is mixed with the inflow air from a common exhaust plenum.
3. Discharges a percentage of air to the outside atmosphere after HEPA filtration.
4. Has all biologically contaminated ducts and plenums under negative pressure or surrounded by negative pressure.
If working with volatile chemicals, the cabinet must be connected to an external exhaust system with a canopy transition.
Type A2 cabinets may be used for work with volatile chemicals if permitted by a chemical risk assessment.