Malvern Zetasizer Nano Series, Accessories Manual

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Chapter 4 Flow-mode option
Page 4-2 MAN 0487
4
In a flow-mode measurement, both the scattered light intensity and hydrodynamic
diameter are plotted as a trend, and the addition of optional analogue inputs enables
the simultaneous display of data from up to two other detector outputs.
ill 7908
By connecting the output from the external device to the external input socket on
the
rear of the Zetasizer Nano, a real-time parameter reading from the device can
be directly inputted back into the Zetasizer Nano software. This parameter reading
can be plotted as a trend, thus enabling additional sample characteristics to be
monitored.
Applications
Applications for this feature include use as a chromatography detector and a process
monitor.
Separations detector
The Zetasizer Nano can be connected to a size-exclusion chromatography (SEC)
system or a field-flow fractionation (FFF) system.
When connected to one of these systems, the Zetasizer Nano acts as a sensitive
light scattering detector, simultaneously plotting trends of the total intensity of
light scattered and the size as the hydrodynamic diameter.
Light scattering is an almost universal detector, as most materials, such as proteins
for example, will have a different refractive index to the buffer they are in, and
hence will produce a light scattering signal.
Auto
Injector
SEC/GPC
Column
Trigger
Data
Pump
Electrical Connections
Eluent
Liquid Connections
Waste
Degasser