Malvern Zetasizer Nano Series, Accessories Manual

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Chapter 6 Advanced protein features
Page 6-4 MAN 0487
Controlling a protein mobility
measurement via an SOP
A protein mobility measurement is divided into two separate measurement parts
- zeta potential and size . The protein mobility measurement follows the same
SOP format as performed when doing a normal zeta potential or size
measurement, with a few exceptions.
The SOP editor and setup is described in full in the Zetasizer Nano user
manual . Most of the SOP sections are common to Measurement types, and these
are described in the above manual. The other SOP sections are specific to the
protein mobility measurement being performed; these are described below. Also
note that some of the other dialogue pages will alter slightly to accommodate extra
parameters necessary to perform the microrheology measurement.
Creating or editing an SOP - Measurement type
selection

To create a new SOP, select File-New SOP . This will open up the SOP edi-
tor. The SOP editor consists of several dialogues that can be stepped through
by using the
Next arrow button.
(To edit an existing SOP, choose Open-SOP instead.)

Complete the SOP editor as described in the Zetasizer Nano user manual.

Once the SOP has been created, press Finish and save the new SOP.
The various SOP dialogues are described below.
Measurement type options
Select a protein mobility measurement type then complete the SOP creation as
required.