Malvern Zetasizer Nano Series, Accessories Manual

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Zetasizer Nano accessories guide Page 5-1
5
Microrheology
Introduction
This chapter gives an overview of the microrheology option in the Zetasizer
software. It can be used with either a Zetasizer Nano ZS or ZSP. The
microrheology option allows the measurement of the viscoelastic modulus of
samples within the linear viscoelastic region.
It describes how to connect, control and operate the microrheology optioned
instrument to ensure reliable and consistent measurements.
DLS Microrheology
The new measurement protocol for the Zetasizer Nano ZS and ZSP has been
called
DLS Microrheology , as it is a cross over between DLS and rheology, and
allows rheological measurements of low viscosity and weakly structured samples to
be made.
Advantages of DLS Microrheology are:

Rheological characterization of low viscosity, weakly-structured samples. Via
access to very high frequency (short time) dynamics which is highly relevant
for dilute samples or weak structures.

Very small sample volumes can be used (approx. 12 μ L). This is particularly
suitable for precious protein samples.

Provides rheological parameters - G
'
, G
''
,
η
*.
Data can be verified using the
same sample measured on a rotational rheometer where measurement ranges
overlap. Data can be exported and used in the Malvern
rSpace software.
ZEN5600
ZEN3600
Zetasizer Nano ZSP instrument
Zetasizer Nano ZS instrument