background image

Prohibited: 

To avoid equipment damage caused by spilled solvent, do not place

reservoir bottles directly atop an instrument or device or on its front ledge. Instead,
place the bottles in the bottle tray, which serves as secondary containment in the event
of spills.

A.4 Required protection

The Use Eye Protection and Wear Protective Gloves symbols alert you to the requirement for
personal protective equipment. Select appropriate protective equipment according to your
organization’s standard operating procedures.

Requirement: 

Use eye protection when performing this procedure.

Requirement: 

Wear clean, chemical-resistant, powder-free gloves when performing

this procedure.

A.5 Warnings that apply to all Waters instruments and

devices

When operating this device, follow standard quality-control procedures and the equipment
guidelines in this section.

Warning: 

Changes or modifications to this unit not expressly approved by the party

responsible for compliance could void the user’s authority to operate the equipment.

Avertissement : 

Toute modification sur cette unité n’ayant pas été expressément

approuvée par l’autorité responsable de la conformité à la réglementation peut annuler
le droit de l’utilisateur à exploiter l’équipement.

Warnung: 

Jedwede Änderungen oder Modifikationen an dem Gerät ohne die

ausdrückliche Genehmigung der für die ordnungsgemäße Funktionstüchtigkeit
verantwortlichen Personen kann zum Entzug der Bedienungsbefugnis des Systems
führen.

Avvertenza: 

qualsiasi modifica o alterazione apportata a questa unità e non

espressamente autorizzata dai responsabili per la conformità fa decadere il diritto
all'utilizzo dell'apparecchiatura da parte dell'utente.

Advertencia: 

cualquier cambio o modificación efectuado en esta unidad que no haya

sido expresamente aprobado por la parte responsable del cumplimiento puede anular la
autorización del usuario para utilizar el equipo.

August 8, 2016, 715005050 Rev. C

Page 129

Содержание ACQUITY UPLC

Страница 1: ...ACQUITY UPLC Quaternary Solvent Manager Overview and Maintenance Guide 715005050 Revision C Copyright Waters Corporation 2016 All rights reserved...

Страница 2: ...ers Web site waters com Trademarks ACQUITY is a registered trademark of Waters Corporation ACQUITY UPLC is a registered trademark of Waters Corporation THE SCIENCE OF WHAT S POSSIBLE is a registered t...

Страница 3: ...Street Milford MA 01757 USA Safety considerations Some reagents and samples used with Waters instruments and devices can pose chemical biological or radiological hazards or any combination thereof You...

Страница 4: ...ance could void the user s authority to operate the equipment This device complies with Part 15 of the FCC Rules Operation is subject to the following two conditions 1 this device may not cause harmfu...

Страница 5: ...nating current Electrical and electronic equipment with this symbol may contain hazardous substances and should not be disposed of as general waste For compliance with the Waste Electrical and Electro...

Страница 6: ...y similar vary the location of the QC samples in the trays Ensure that QC sample results fall within an acceptable range and evaluate precision from day to day and run to run Data collected when QC sa...

Страница 7: ...rized representative Address Waters Corporation Stamford Avenue Altrincham Road Wilmslow SK9 4AX UK Telephone 44 161 946 2400 Fax 44 161 946 2480 Contact Quality manager August 8 2016 715005050 Rev C...

Страница 8: ...ing this device iv Applicable symbols v Audience and purpose v Intended use of the QSM vi Calibrating vi Quality control vi EMC considerations vi Canada spectrum management emissions notice vi ISM cla...

Страница 9: ...and degasser vent tubing 25 2 3 Electricity source 28 2 3 1 Connecting to a wall electricity source 28 2 3 2 Connecting to a cart s electricity source 28 2 4 Connecting signal cables 29 2 4 1 Input ou...

Страница 10: ...ling the i2Valve cartridge on the actuator 72 3 17 4 Installing the i2Valve actuator 76 3 18 Replacing the primary pump head s plunger and seals 79 3 18 1 Moving the plunger backward 80 3 18 2 Removin...

Страница 11: ...133 A 7 Electrical symbols 135 A 8 Handling symbols 136 B Specifications 137 B 1 QSM and bioQSM physical specifications 137 B 2 QSM and bioQSM environmental specifications 137 B 3 QSM and bioQSM elec...

Страница 12: ...n accuracy or precision A gradient proportioning valve GPV to dynamically blend solvents in any specified combination The GPV produces predictable gradient segments regardless of solvent compressibili...

Страница 13: ...esulting in significant time savings 1 1 2 Auto Blend Plus Auto Blend Plus technology uses pure solvents and concentrated stocks to blend mobile phase compositions at a specific pH At the same time it...

Страница 14: ...us of the module This LED is green when power is on and unlit when power is off Flow LED Indicates the flow status A steady green flow LED indicates that there is a flow through the solvent manager Do...

Страница 15: ...the tubing that directs waste liquid to the waste container Solvent vent tubing Vents solvent to waste during priming Location of leak sensor The leak sensor continuously monitors the solvent manager...

Страница 16: ...lvents upstream of the pumps i2Valve Electronically controlled ball check valve that allows flow in only one direction Primary pump Draws solvent transferring it to the accumulator pump and system as...

Страница 17: ...cer APT which measures the pressure on the low pressure side of the degasser system is unaffected by altitude or barometric changes Table 1 1 Absolute pressure transducer attributes Item Absolute pres...

Страница 18: ...tered solvents 4 The blended solvents flow through the i2Valve check valve and into the primary piston chamber 5 The primary piston delivers solvent to the accumulator the vent valve and the in line m...

Страница 19: ...part number 715001307 Notice To avoid damaging solvent manager components do not use chloroform methylene chloride or toluene do not use ethyl acetate hexane or tetrahydrofuran THF without the hexane...

Страница 20: ...ies with ferrules not previously assembled or set to tubing you must mark the compression screw and fitting body and ensure that the two marks line up when you tighten them Requirement Wear clean chem...

Страница 21: ...th short flats and 2 piece stainless steel ferrule First use Short flats Compression screw 2 piece stainless steel ferrule Tighten the fitting finger tight plus an additional 3 4 turn using a 1 4 inch...

Страница 22: ...ight plus as much as an additional 1 6 turn using a 1 4 inch open end wrench Re installed tightening 2 1 3 Stainless steel gold plated fitting with long flats and 2 piece stainless steel ferrule First...

Страница 23: ...o prevent band spreading ensure that the tubing is fully bottomed in the fitting before tightening the compression screw First use tightening Re installed Long flats Compression screw 2 piece stainles...

Страница 24: ...of lock ring with larger inside diameter ID Tighten the fitting finger tight 2 1 5 Short 1 4 28 fitting with flangeless ferrule and stainless steel lock ring installed on 1 16 inch OD tubing First us...

Страница 25: ...finger tight 2 2 Installing and routing the waste and degasser vent tubing Notice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this proced...

Страница 26: ...drain fitting located at the bottom of the solvent manager with methanol 2 Hold the back of the drain cup slide the waste tubing over the barbed drain fitting and route the tubing to a suitable waste...

Страница 27: ...d false leak sensor alarms ensure proper drainage of waste Place the waste container below the system stack to permit gravity flow Ensure that the waste and degasser vent tubes do not crimp or bend A...

Страница 28: ...rical shock observe these precautions Use SVT type power cord in the United States and HAR type power cord or better in Europe For requirements elsewhere contact your local Waters distributor Inspect...

Страница 29: ...s electrical cables included in the startup kit to the receptacle on the rear panel of each system module 2 Connect the hooded male end of the cart s electrical cables to the power strips on its back...

Страница 30: ...gnal cable to the connector Figure 2 4 Positive and negative lead connections Screw Connector Signal cable 3 Fit the grounding cable s fork terminal on the rear panel grounding stud and secure the ter...

Страница 31: ...condition or hardware failure on another instrument or device for example beginning a gradient separation Stop flow Stops the flow from the solvent manager when it receives a contact closure input or...

Страница 32: ...cal components and circuitry do not disconnect an electrical assembly while electrical power is applied to a module To completely interrupt power set the on off switch to the off position and then dis...

Страница 33: ...te the plungers fill the tubing paths with solvent and flush away solvent and any precipitated salts that have been dragged past the plunger seals from the high pressure side of the piston chambers Pr...

Страница 34: ...tems part number 715001307 on the ACQUITY UPLC System Bookshelf CD Required tools and materials Chemical resistant powder free gloves 30 mL syringe startup kit Seal wash solution Tubing adapter startu...

Страница 35: ...e priming a dry solvent manager using a syringe shortens the time required for priming Recommendation Ensure that solvents which combine at the inlet manifold are fully miscible Notice To prevent salt...

Страница 36: ...ath is primed Requirement Ensure that enough solvent remains in the solvent reservoirs to supply subsequent methods 2 7 2 Priming a dry solvent manager using a syringe Warning Observe Good Laboratory...

Страница 37: ...nd retract the tubing lifting it away from the drip tray 4 Push the syringe plunger fully into the syringe barrel 5 Connect the tubing adapter to the syringe 6 Connect the syringe assembly to a short...

Страница 38: ...gh solvent for future methods 2 8 Washing the plungers The plunger wash function washes the plungers with seal wash solvent It is designed to prevent the build up of precipitates on the pump plungers...

Страница 39: ...garding the solvents you use Additionally consult the safety representative for your organization regarding its protocols for handling such materials Warning To avoid personal contamination with bioha...

Страница 40: ...the leak and make the repairs necessary to stop it Notice To avoid damaging the leak sensor do not grasp it by the ribbon cable 5 Remove the leak sensor from its reservoir grasping the sensor by its...

Страница 41: ...and its surrounding area 9 Align the leak sensor s T bar with the slot in the side of the leak sensor reservoir and slide the leak sensor into place Figure 2 14 Aligning T bar with slot T bar Slot in...

Страница 42: ...or Leak sensor connector Leak sensor port on front of device 11 Power on the solvent manager 12 In the console select the solvent manager and then click Control Reset module to reset the solvent manag...

Страница 43: ...Waters Web site includes phone numbers and e mail addresses for Waters locations worldwide Visit www waters com When you contact Waters be prepared to provide this information Error message if any Nat...

Страница 44: ...Alternatives In the main window point to the visual representation of the system module that you want information about Obtain the serial number from the printed labels on the module s rear panel or...

Страница 45: ...cartridge During scheduled routine maintenance or as necessary Replace the accumulator check valve During scheduled routine maintenance or as necessary Replace the pump head seals and plungers During...

Страница 46: ...a particular component provide information about real time usage that can help you determine when to schedule routine maintenance for specific components You can specify usage thresholds and maintena...

Страница 47: ...s materials Consult the Material Safety Data Sheets regarding the solvents you use Additionally consult the safety representative for your organization regarding its protocols for handling such materi...

Страница 48: ...ubing to remove any air from the filter 6 Prime the solvent manager see Priming the solvent manager 3 9 Replacing the leak sensor Warning Observe Good Laboratory Practice GLP at all times particularly...

Страница 49: ...hereafter before disconnecting an assembly 1 Power off the solvent manager 2 Open the solvent manager s door 3 Press down on the tab to detach the leak sensor connector from the front of the device Fi...

Страница 50: ...tray 8 Connect the leak sensor connector to the front of the device Figure 3 6 Attaching leak sensor connector Leak sensor connector Leak sensor port on front of device 9 Power on the solvent manager...

Страница 51: ...the inlet manifold 1 Power off the solvent manager 2 Open the solvent manager s door 3 Disconnect the finger tight outlet tubing fitting from the inlet manifold outlet Figure 3 7 Outlet tubing fitting...

Страница 52: ...isconnect the inlet tubing fittings from the inlet manifold Figure 3 9 Inlet tubing fittings on manifold 1 Inlet tubing fitting 4 6 Remove the inlet manifold from the mounting bracket 7 Ensuring its g...

Страница 53: ...ting 4 10 Reattach the outlet tubing fitting to the inlet manifold and tighten it with your fingers to the extent possible Requirement Ensure the outlet tubing is fully engaged by raising the inlet ma...

Страница 54: ...Additionally consult the safety representative for your organization regarding its protocols for handling such materials Warning To avoid personal contamination from contact with biologically hazardou...

Страница 55: ...hereafter before disconnecting an assembly 1 Power off the solvent manager 2 Open the solvent manager s door 3 Disconnect the four inlet manifold tubes from the GPV outlets Figure 3 14 GPV outlets 1 G...

Страница 56: ...such materials Notice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gl...

Страница 57: ...he 1 4 inch open end wrench tighten the fittings an additional 1 6 turn for existing fittings or 3 4 turn for new fittings 3 13 Installing or replacing the optional 250 L mixer filter Warning Observe...

Страница 58: ...ect the outlet compression fitting by using the 1 4 inch open end wrench Figure 3 18 Location of outlet compression fitting 1 2 Mixer filter Outlet compression fitting 5 Using the 5 8 inch open end wr...

Страница 59: ...clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materials Chem...

Страница 60: ...e Avoid scratching the drive clamp or body Figure 3 21 Correct vent valve cartridge and drive clamp groove alignment Aligned grooves Vent valve cartridge housing Drive clamp 9 Insert the new vent valv...

Страница 61: ...otice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves when perform...

Страница 62: ...t selection valve cartridge 1 Hex screw 6 Remove the cartridge from the vent valve assembly by pulling straight forward 7 Unpack the replacement cartridge 8 Ensure that the groove in the cartridge hou...

Страница 63: ...ex wrench to tighten it 11 Reattach all fittings and finger tighten them 12 Return the solvent bottles to their original location 13 Prime the solvent manager see Priming the solvent manager Requireme...

Страница 64: ...lvent manager 3 Using the 5 16 inch open end wrench to hold the check valve in place disconnect the compression fitting by using the 1 4 inch open end wrench Figure 3 25 Compression fitting on check v...

Страница 65: ...5 Unpack the new check valve 6 Ensure that the new PEEK washer is inserted into the new check valve so that its chamfered edge faces away from the check valve Figure 3 27 Accumulator check valve 1 2 3...

Страница 66: ...Consult the Material Safety Data Sheets regarding the solvents you use Additionally consult the safety representative for your organization regarding its protocols for handling such materials Warning...

Страница 67: ...ding its protocols for handling such materials Warning To avoid personal contamination from contact with biologically hazardous or toxic materials do not attempt to force or draw liquid or gas through...

Страница 68: ...t manager Tip The solvent manager is referred to as pump on the warning label affixed to the i2Valve actuator 2 Open the solvent manager s door Notice To avoid damaging the connector or cable grasp th...

Страница 69: ...ect the inlet manifold outlet tubing fitting on the side of the i2Valve and remove the tubing Figure 3 30 Inlet manifold outlet tubing fitting 1 2 3 Inlet manifold outlet tubing fitting Inlet manifold...

Страница 70: ...her which is normally on the top face of the i2Valve cartridge does not remain in the pump head never place the actuator assembly or electrical connector in the drip tray 7 Remove the i2Valve actuator...

Страница 71: ...g the i2Valve actuator do not attempt to force or draw liquid or gas through the valve s inlet or outlet ports Notice To avoid contaminating system components wear clean chemical resistant powder free...

Страница 72: ...oid personal contamination from contact with biologically hazardous or toxic materials do not attempt to force or draw liquid or gas through the valve s inlet or outlet ports Notice To avoid damaging...

Страница 73: ...endation Replace the cartridge whenever you replace the i2Valve actuator 4 Ensure that the PEEK washer is inserted into the cartridge so that its chamfered edge faces away from the cartridge Figure 3...

Страница 74: ...r 1 2 Grooved end of cartridge i2Valve actuator 6 With one hand squeeze the 2 clamping plate tabs on the i2Valve actuator to hold the clamping plates against the cartridge Figure 3 36 i2Valve Clamping...

Страница 75: ...below 8 Repeat the torquing pattern shown below at least three times gradually increasing the torque until the screws are uniformly tight Figure 3 37 Screw torquing pattern 1 2 3 4 Tip You can rotate...

Страница 76: ...let ports Notice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves w...

Страница 77: ...anifold outlet tubing fitting 1 2 3 Inlet manifold outlet tubing fitting Inlet manifold i2Valve 6 Reattach the outlet tubing fitting to the inlet manifold and tighten it with your fingers to the exten...

Страница 78: ...to tighten the fitting an additional 1 6 turn for existing fittings or 3 4 turn for new fittings Figure 3 42 Inlet manifold outlet tubing fitting 1 2 3 Inlet manifold outlet tubing fitting Inlet manif...

Страница 79: ...ood Laboratory Practice GLP at all times particularly when working with hazardous materials Consult the Material Safety Data Sheets regarding the solvents you use Additionally consult the safety repre...

Страница 80: ...alling the pump head 10 Reinstalling the i2Valve actuator 11 Performing the solvent manager leak test see the console online Help Tip If the leak test results are unsatisfactory pressurize the seals t...

Страница 81: ...nt Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materials Chemical resistant powder free gloves 1 4 inch open end wrench 5 16 inch open end wrench...

Страница 82: ...finger tight outlet tubing fitting on the inlet manifold outlet Figure 3 45 Outlet tubing fitting on manifold 1 2 Outlet tubing fitting Inlet manifold 5 Use the 1 4 inch open end wrench to disconnect...

Страница 83: ...the shell nut 1 2 3 Pump head Shell nut i2Valve Notice To avoid damaging the i2Valve actuator assembly when removing it ensure that the PEEK washer which is normally on the top face of the i2Valve car...

Страница 84: ...s for handling such materials Notice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant...

Страница 85: ...2 Using a pliers remove the drip wire from the head assembly Figure 3 50 Removing drip wire 1 2 Drip wire Pliers 3 Using the 1 4 inch open end wrench disconnect the outlet tubing from the transducer F...

Страница 86: ...accessible from the front of the pressure transducer Figure 3 53 Head bolts on primary pump head 1 Head bolts Notice To avoid damaging the plunger support the head from below as you remove it and do...

Страница 87: ...ry Practice GLP at all times particularly when working with hazardous materials Consult the Material Safety Data Sheets regarding the solvents you use Additionally consult the safety representative fo...

Страница 88: ...en removing head assembly components Bending or twisting the sapphire piston shaft can cause it to fracture or splinter 1 Use the recessed side of the plunger removal tool to apply pressure to both si...

Страница 89: ...cal resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materials Chemical resist...

Страница 90: ...4 Remove the old seal wash seal from the seal wash housing and discard the old seal Figure 3 60 Location of seal wash seal Seal wash seal Seal wash housing 5 Using the smooth end of the seal removal t...

Страница 91: ...to scratch any metal surfaces screw the threaded end of the seal removal tool into the plunger seal and carefully withdraw the seal from the pump head Figure 3 62 Removing plunger seal 1 2 Plunger se...

Страница 92: ...aterials Notice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves wh...

Страница 93: ...plunger seal with methanol and use the smooth end of the seal removal tool to place it in the pump head Figure 3 65 Placing plunger seal in pump head 1 2 3 4 Plunger seal Seal removal tool Seal remov...

Страница 94: ...1 Plunger seal spacer 4 Orient the seal wash housing so that the holes on its side align with the holes on the side of the pump head and then guide it into place Figure 3 67 Installing seal wash housi...

Страница 95: ...eal wash seal Seal wash housing 6 Place the support plate on top of the pump head ensuring that the round side of the plate is oriented toward the bottom side of the pump head Figure 3 69 Placing supp...

Страница 96: ...s Consult the Material Safety Data Sheets regarding the solvents you use Additionally consult the safety representative for your organization regarding its protocols for handling such materials Notice...

Страница 97: ...ls with methanol Figure 3 71 Pump head seals Pump head seals 2 Carefully insert the plunger shaft into the pump head until the shaft is no longer visible Requirement Ensure that the shaft does not mak...

Страница 98: ...rforming this procedure Requirement Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materials Chemical resistant powder free gloves 1 4 inch open end...

Страница 99: ...Figure 3 73 Support plate bolts on primary pump head 1 Support plate bolts 3 Alternately tighten the head bolts so that they are uniformly torqued Figure 3 74 Head bolts on primary pump head 1 Head b...

Страница 100: ...transducer cable in connector 1 2 Connector Tabs 6 Reattach the outlet tubing fitting to the transducer tighten it with your fingers to the extent possible and then use the 1 4 inch open end wrench to...

Страница 101: ...vents you use Additionally consult the safety representative for your organization regarding its protocols for handling such materials Warning To avoid personal contamination from contact with biologi...

Страница 102: ...xits from the left hand side 2 Insert the i2Valve assembly into the bottom of the primary pump head and route the cable behind the valve actuator 3 Tighten the shell nut using your fingers rotating th...

Страница 103: ...the outlet tubing is fully engaged by raising the inlet manifold while attaching the outlet tubing fitting Figure 3 81 Reattaching outlet tubing fitting 1 2 Outlet tubing fitting Inlet manifold 7 Tig...

Страница 104: ...or with the white arrow on the receptacle in the 12 o clock position and insert the connector into the receptacle Figure 3 83 Inserting i2Valve connector into receptacle 1 2 3 i2Valve connector Connec...

Страница 105: ...ves when performing this procedure Requirement Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materials Chemical resistant powder free gloves 1 4 in...

Страница 106: ...nt to move backward 4 Click Move Backward and then wait for the plunger to stop 3 19 2 Removing the accumulator pump head Warning Observe Good Laboratory Practice GLP at all times particularly when wo...

Страница 107: ...ng as close to the pump head as possible Figure 3 84 Location of seal wash tubing Seal wash tubing Seal wash tubing 2 Using the pliers remove the drip wire from the head assembly Figure 3 85 Removing...

Страница 108: ...he tubing connection from the check valve using the 1 4 inch open end wrench Figure 3 87 Location of check valve tubing connection Check valve Place 5 16 inch open end wrench here Place 1 4 inch open...

Страница 109: ...bolts on accumulator pump head 1 Head bolts Notice To avoid damaging the plunger support the head from below as you remove it and do not tilt the head when withdrawing it 7 Using the T27 TORX driver l...

Страница 110: ...lunger Warning Observe Good Laboratory Practice GLP at all times particularly when working with hazardous materials Consult the Material Safety Data Sheets regarding the solvents you use Additionally...

Страница 111: ...hand lacerations from sharp edged surfaces use care when removing head assembly components Bending or twisting the sapphire piston shaft can cause it to fracture or splinter 1 Use the recessed side of...

Страница 112: ...ts wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materi...

Страница 113: ...Remove the old seal wash seal from the seal wash housing and discard the old seal Figure 3 96 Location of seal wash seal Seal wash seal Seal wash housing 5 Using the smooth end of the seal removal to...

Страница 114: ...to scratch any metal surfaces screw the threaded end of the seal removal tool into the plunger seal and carefully withdraw the seal from the pump head Figure 3 98 Removing plunger seal 1 2 Plunger sea...

Страница 115: ...materials Notice To avoid contaminating system components wear clean chemical resistant powder free gloves when performing this procedure Requirement Wear clean chemical resistant powder free gloves w...

Страница 116: ...plunger seal with methanol and use the smooth end of the seal removal tool to place it in the pump head Figure 3 101 Placing plunger seal in pump head 1 2 3 4 Plunger seal Seal removal tool Seal remov...

Страница 117: ...Plunger seal spacer 4 Orient the seal wash housing so that the holes on its side align with the holes on the side of the pump head and then guide it into place Figure 3 103 Installing seal wash housi...

Страница 118: ...al wash seal Seal wash housing 6 Place the support plate on top of the pump head ensuring that the round side of the plate is oriented toward the bottom side of the pump head Figure 3 105 Placing supp...

Страница 119: ...ls Consult the Material Safety Data Sheets regarding the solvents you use Additionally consult the safety representative for your organization regarding its protocols for handling such materials Notic...

Страница 120: ...s with methanol Figure 3 107 Pump head seals Pump head seals 2 Carefully insert the plunger shaft into the pump head until the shaft is no longer visible Requirement Ensure that the shaft does not mak...

Страница 121: ...rocedure Requirement Wear clean chemical resistant powder free gloves when performing this procedure Required tools and materials Chemical resistant powder free gloves 1 4 inch open end wrench 5 16 in...

Страница 122: ...e 3 109 Support plate bolts on accumulator pump head 1 Support plate bolts 3 Alternately tighten the head bolts so that they are uniformly torqued Figure 3 110 Head bolts on accumulator pump head 1 He...

Страница 123: ...le to the bulkhead Figure 3 112 Pressure transducer cable in connector 1 2 Connector Tabs 6 Using the 5 16 inch open end wrench to hold the check valve cartridge in place reconnect the tubing connecti...

Страница 124: ...ransducer tighten it with your fingers to the extent possible and then use the 1 4 inch open end wrench to tighten the fitting an additional 1 6 turn for existing fittings or 3 4 turn for new fittings...

Страница 125: ...instrument or device Do not spray or otherwise apply water directly onto any equipment surface Warning To avoid personal injury use eye and hand protection during the cleaning process Requirement Use...

Страница 126: ...or property damage resulting from the failure of individuals to comply with any safety precaution when installing repairing or operating any of its instruments or devices The following symbols warn of...

Страница 127: ...nts and devices fitted with nonmetallic tubing Warning To avoid injury from bursting nonmetallic tubing heed these precautions when working in the vicinity of such tubing when it is pressurized Wear e...

Страница 128: ...an process biohazards corrosive materials or toxic materials Warning To avoid personal contamination with biohazards toxic materials or corrosive materials you must understand the hazards associated w...

Страница 129: ...ges or modifications to this unit not expressly approved by the party responsible for compliance could void the user s authority to operate the equipment Avertissement Toute modification sur cette uni...

Страница 130: ...f the tubing Avertissement Manipulez les tubes en polym re sous pression avec precaution Portez syst matiquement des lunettes de protection lorsque vous vous trouvez proximit de tubes en polym re pres...

Страница 131: ...ostante Non utilizzare tubi eccessivamente logorati o piegati Non utilizzare tubi non metallici con tetraidrofurano THF o acido solforico o nitrico concentrati Tenere presente che il cloruro di metile...

Страница 132: ...THF Methylene chloride Dimethyl sulfoxide THF This warning applies to Waters instruments fitted with nonmetallic tubing This warning applies to instruments operated with flammable solvents August 8 2...

Страница 133: ...recchiatura secondo modalit non previste dal produttore pu compromettere la protezione offerta dall apparecchiatura Advertencia el usuario deber saber que si el equipo se utiliza de forma distinta a l...

Страница 134: ...on does not appear on the instrument or device Warning To protect against fire replace fuses with those of the type and rating indicated in the Replacing fuses section of the Maintenance Procedures ch...

Страница 135: ...trument manuals and on an instrument s front or rear panels Symbol Description Electrical power on Electrical power off Standby Direct current Alternating current Alternating current 3 phase Safety gr...

Страница 136: ...can appear on labels affixed to the packaging in which instruments devices and component parts are shipped Symbol Description Keep upright Keep dry Fragile Use no hooks Upper limit of temperature Lowe...

Страница 137: ...in with 2 2 cm 0 875 in feet Width 34 3 cm 13 5 in Depth 66 1 cm 26 0 in Weight 27 5 kg 60 5 lb B 2 QSM and bioQSM environmental specifications Attribute Specification Acoustic noise 65 dBA system Am...

Страница 138: ...eir electrical power from a local level such as an electrical wall outlet c Pollution Degree 2 A measure of pollution on electrical circuits that can produce a reduction of dielectric strength or surf...

Страница 139: ...solvent A with i2Valve Back pressure 4137 to 6895 kPa 41 to 69 bar 600 to 1000 psi with degassed water Flow precision 0 075 RSD or 0 020 min SD whichever is greater based on six replicates i2Valve Tes...

Страница 140: ...5 C 0 3 C Detector UV 254 nm wavelength Compressibility compensation Automatic and continuous Priming Wet priming can run at flow rates up to 4 mL min Pump seal wash Equipped with a wash system to flu...

Страница 141: ...tainless steel DLC fluoroelastomer fluoropolymer Nitronic 60 PEEK PEEK blend PPS ruby sapphire titanium alloy UHMWPE blend zirconia bioQSM DLC fluoroelastomer fluoropolymer Nitronic 60 PEEK PEEK blend...

Отзывы: