U
SER
M
ANUAL
&
T
ECHNICAL
D
ESCRIPTION
N-LINEpro_User Manual_2018-09-20.doc
MEDlight GmbH
Werrestr. 94
32049 Herford
Germany
Phone: +49 5221 99429-0
Fax: +49 5221 99429-40
e-mail: [email protected]
www.medlight.eu
Page 25 of 30
Because of the risk of accumulation of the phototoxic effect of successive PUVA treatments due to the
much-delayed phototoxic reaction, after two days of irradiation, an irradiation-free day is provided. This
avoids strong excessive phototoxic reactions. Thus results in a scheme by which patients are treated on
Monday, Tuesday, Thursday and Friday. Wednesday, Saturday and Sunday provide rest and observation
days. During the initial phase, at least three treatments per week are desirable. During PUVA treatment
occurs as a result of the increasing pigmentation and thickening of the epidermis, a habituation effect
(tolerance). The extent of the tolerance development depends on the skin type. In patients with skin
type I or II, the tolerance development is slow, therefore the dose should be increased very carefully. In
patients with skin types III, IV, V and VI, the UV tolerance develops rapidly, accordingly quickly can the
UVA dose be increased. To avoid an overdosing by accumulation, it must be taken into account for the
dose adjustments, that the maximum PUVA erythema appears 72 to 120 hours after irradiation.
Because of the higher level of sensibilization, the irradiation doses for bath PUVA treatments are
generally lower. It has to be noted that the MPD can drop by up to 50% during the first therapy week,
but later rises again. The reason for this is not known, it is believed that psoralen monoadducts persist in
the DNA and being transformed in subsequent irradiations into phototoxic effective biadducts.
Generally, it is recommended to increase in the bath PUVA treatment only once a week the dose.
Source: Prof. Dr. E. Hölze, et Al. ‚Empfehlungen zur UV-Phototherapie und Photochemotherapie‘ DDG Berlin 2009
8
TECHNICAL SPECIFICATIONS & INFORMATION
8.1
Technical Data
Power supply:
400 V, 50 Hz, 16 amps, 3 phase
Mains fuses in device:
10 amps (time-lag)
Power consumption:
4900 VA
Dimensions W x D x H:
121 x 114 x 222 cm (47.6" x 44.9" x 87.4")
Weight:
330 kg (728 lb)
Mode of operation:
Continuous
Electrical appliance class:
Class I Equipment
Applied parts classification:
The appliance is a Type B Applied Part
Ingress protection classification:
IPX0