NuAire LabGard D NU-543-400, Manual

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OM0283 Page 5 of 70
Rev 2 July/2021
LabGard® ES Energy Saver
Class II, Type A2 Laminar Flow
Biosafety Cabinet
Models
NU-543-300/400/500/600
Manufactured by:
NuAire, Inc. - Plymouth, Minnesota, U.S.A.
1.0 General Information
1.1 Description
The LabGard® ES Model NU-543 Laminar Flow Biosafety Cabinet (LFBSC) is a bench/table top model, optionally available
with a base support stand, for operation as a console model. The LabGard® ES model NU-543 utilizes an Energy Saver DC
ECM motor optimally determined forward curved fan for each model size/width to maximize both energy efficiency and
filter loading capacity. The Energy Saver ECM motor is controlled to airflow setpoints by the
FlowGard™ control system via
an integrated solid-state DC motor controller based on feedback algorithm to provide automatic compensation (constant
volume control) for both filter loading and line voltage variances. Airflow velocity is monitored with the Intelliflow digital
dual thermistor airflow sensor.
The Laminar Flow Biosafety Cabinet, (LFBSC) is a product resulting from the development of the "laminar flow" principle
(see Airflow Schematic) and the application of environmental controls as required in the field of biological research or
chemical containment. The LFBSC, when used with proper technique, is an effective primary engineering control in
obtaining the optimum product quality while reducing the potential for exposure of both product and personnel to airborne
biological or particulate chemical agents in low to moderate risk-hazard research and drug preparation or product
operations, as prescribed by the Center for Disease Control (CDC) Atlanta, Georgia.
The NU-543 bench LFBSC meets the requirements of a Class II, since the cabinet conforms to the following requirements:
1. Maintains a minimum inflow velocity of 100 LFPM (.51mps) through the work access opening.
2. Has HEPA filtered downflow air that is mixed with the inflow air from a common exhaust plenum.
3. Discharges a percentage of air to the outside atmosphere after HEPA filtration.
4. Has all biologically contaminated ducts and plenums under negative pressure or surrounded by negative pressure.
Cabinets used for work with minute quantities of non-flammable or explosive volatile toxic chemicals and tracer amounts of
radionuclides required as an adjunct to microbiological studies must be exhausted through properly functioning exhaust
canopies.