27
TCI with B. Braun Space is possible with two drugs: Propofol and Remifentanil.
For Propofol the user can choose between two parameter sets. The parameter
sets used for these drugs are (Not all parameter sets allow effect-site targeting):
Chapter 3
SPECIAL FUNCTIONS
Drug / Parameter
V
1
[Litre]
Propofol
Remifentanil
k
12
[min
-1
]
0,112
0,119
k
13
[min
-1
]
0,0419
k
21
[min
-1
]
0,055
k
31
[min
-1
]
0,0033
k
e0
[min
-1
]
0,26
Reference
Marsh et al., Br. J.
Anaesthesia, Vol.
67, 1991, 41-48
Effect-site
targeting
No
k
10
[min
-1
]
0,228 * Weight
0,302 - 0,0056 * (Age - 53)
0,443 + 0,0107 * (Weight -
77) - 0,0159 * (LBM - 59) +
0,0062 * (Height - 177)
0,196
[1,29 - 0,024 * (Age - 53)] /
[18,9 - 0,391 * (Age - 53)
0,0035
0,456
Schnider et al., Anesthesio-
logy, Vol. 88, 1998, 1170-
1182 Schnider et al.,
Anesthesiology, Vol. 90,
1999, 1502-1516
Yes
4,27
[2,05 - 0,0301 * (Age - 40)] /
[5.1 - 0.0201 * (Age - 40) +
0.072 * (LBM - 55)]
[2,6 - 0,0162 * (Age - 40) +
0,0191 * (LBM - 55)] / [5.1 -
0.0201 * (Age - 40) + 0.072 *
(LBM - 55)]
[0,076 - 0,00113 * (Age - 40)] /
[5.1 - 0.0201 * (Age - 40) +
0.072 * (LBM - 55)]
[2,05 - 0,0301 * (Age - 40)] /
[9,82 - 0,0811 * (Age - 40) +
0,108 * (LBM - 55)]
0.01402 - 0,0002085 *
(Age -40)
0,595 - 0,007 * (Age - 40)
Minto et al., Anesthesiology,
Vol. 86, 1997, 10-33
Yes
5,1 - 0,0201 * (Age - 40) +
0,072 * (LBM - 55)
