Angioscan Electronics AngioScan-01, User Manual, Page: 50 / 119

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© 2014 AngioScan-Electronics LLC
AngioScan Medical Tests
increased shear stress leads to the activation of nitric oxide synthesis by endothelial cells. A local
increase in the concentration of nitric oxide has an impact on the tone of smooth muscles of the
arteries, leading to their dilation. When dilation of the brachial artery occurs, the pulse wave amplitude
increases.
Thus, the increase in the pulse wave amplitude registered with the Angioscan device is associated with
the flow-mediated dilation of the brachial artery.
4.2.1 Patient preparation requirements
1. The testing should be done in the morning after fasting overnight.
2. Smoking, vasoactive drugs, caffeine, alcohol, and other stimulants and moderate and intense
exercise has to be terminated one day before the test.
3. Immediately prior to the test, the subject should rest for 15 minutes in a warm, darkened and quiet
room.
4. During the test, the subject should be in supine position with his arms placed along his body. The test
is conducted in a warm, darkened and quiet room.
4.2.2 Occclusion test procedure
The occlusion test procedure with Angioscan device consists of the following steps:
1. Measure arterial blood pressure with a certified device based on the standard oscillometric method.
2. If necessary, create a new patient profile in the "Patient Database" window. To add a new patient,
click "New" and fill out the form: name, date of birth, gender, height and comments. Then click "OK"
to save the patient data. This needs to be done only once for each patient. After doing so, all future
test results for each previously saved patient profile will be stored in the database.