3DHISTECH TMA Grand Master 2.1 User Manual Download Page 75

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TMA Grand Master 2.1 – User’s Guide

9 Technical Description of the Hardware

9 Technical Description of the Hardware

9.1 Physical Dimensions and Weight

Name of the Unit

Dimensions in mm*
(Width x Depth x Height)

Weight in kg*

TMA Grand Master main unit

807×505×444

Control Computer

206×560×440

Max. 10

Monitor (22")

512×44×352

Max. 3.3

* approximate values

9.2 Accessories

Accessory

Dimensions in mm

Number of items

Base mold for paraffin blocks

37×24×7,5

Drill bit*

0.6

1.0

/ Ø

1.5

2.0

2 / 2 / 2 / 2

Puncher*

0.6

1.0

/ Ø

1.5

2.0

3 / 3 / 3 / 3

Puncher chuck and Drill bit chuck

N/A

Piston*

0.6

1.0

/ Ø

1.5

2.0

1 / 1 / 1 / 1

* For Drill bits, Punchers, and Pistons there are four distinctive color markings for each different

sizes as follows:

•

colorless – Ø 0.6mm

•

black – Ø 1mm

•

magenta – Ø 1.5mm

•

blue – Ø 2mm

April 8, 2014 – Rev. 1

3DHISTECH Ltd.

75(79)

Summary of Contents for TMA Grand Master 2.1

Page 1: ...GM21 UG EN Rev1 TMA Grand Master 2 1 User s Guide April 8 2014 Rev 1 ...

Page 2: ... Main Unit 21 4 1 Switching the Main Unit On or Off 21 4 2 Starting the TMA Grand Master Application 21 4 3 Main User Interface 24 4 3 1 Main Toolbar 25 4 4 Inserting and Removing Blocks 26 4 4 1 Block preparation 26 4 4 2 Cleaning block and PCR cassette preparation 27 4 4 3 Inserting a block into the main unit 28 4 4 4 Removing a block from the main unit 30 4 4 5 Removing a PCR cassette from the ...

Page 3: ...67 6 2 1 Opening the Service Compartment Door 68 6 3 Replacing fuses of the main power switch 69 6 4 Contaminated Tray or Touch Sensor Surface 70 7 Troubleshooting TMA Grand Master 72 7 1 Hardware related issues 72 7 2 Software related issues 73 8 Cassette and Block Dimensions 74 9 Technical Description of the Hardware 75 9 1 Physical Dimensions and Weight 75 9 2 Accessories 75 9 3 Objective and C...

Page 4: ...e analysis of the digitized slides for example change of health status related to erroneous diagnosis from the digitized slide s that stems from or is associated with use of Product digitized slides quality of staining quality of stained slides quality of used method of staining 3DHISTECH Ltd assumes no responsibility for the functionality and fault free condition of your application programs Work...

Page 5: ...iness information pecuniary loss or similar damage that stems from or is associated with the incorporated part of this Product that is made by Silicon Graphics Inc THE SOFTWARE IS PROVIDED AS IS AND WITHOUT WARRANTY OF ANY KIND EXPRESSED IMPLIED OR OTHERWISE INCLUDING WITHOUT LIMITATION ANY WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE IN NO EVENT SHALL SAM LEFFLER OR SILICON GRA...

Page 6: ...rement control and laboratory use Part 2 101 Particular requirements for in vitro diagnostic IVD medical equipment DIN EN 55011 2009 Class B Limits and methods of measurement of radio disturbance characteristics of industrial scientific and medical ISM radio frequency equipment Conformity with Directive 98 79 EC is documented by the TMA Grand Master label This product has been tested to the requir...

Page 7: ... key combination Example Cross references to other documents or sections within this document Warning Indicates that you need an additional module to use the feature there are prerequisites for the task or that special care should be taken when using certain feature of the device Important An important piece of information or a recommendation The application will work if you choose not to follow t...

Page 8: ...he tissue cores are removed from the donor and inserted into a recipient paraffin block Clone Block A duplicate triplicate quadruplicate etc of a recipient block with identical layout and core order TMA Tissue microarrays The tissue microarray consists of an array of cylindrical cores of paraffin embedded tissue that are removed from preexisting donor paraffin blocks PCR Polymerase Chain Reaction ...

Page 9: ...le mechanical main unit It has an intuitive operation control via the keyboard and the mouse of a PC connected to the main unit The device measures the height of donor blocks the value is displayed next to the donor block thumbnail image based on which the software calculates the depth of punch drill and insertion Thus embedded cores are placed correctly into the recipient block resulting in an ev...

Page 10: ... cables between the main unit and the control computer Accessories box Blocks Base molds for paraffin blocks 2 1 TMA Grand Master Main Unit Front View Figure 1 TMA Grand Master front view 1 Protective housing 2 Door opener button 3 Tool change compartment door 4 Protective window 5 Trash container for paraffin flakes and discarded core material April 8 2014 Rev 1 3DHISTECH Ltd 10 79 ...

Page 11: ...th the computer 2 2 Cabling For required cable connections the supplied cables must be plugged in as shown in the figure above To connect the main unit with the computer any of the three USB ports can be used Warning All cable connections must be checked for firm seating Defective cables must not be connected to any part and must be replaced with cables in proper operating condition Contact 3DHIST...

Page 12: ... shock 2 3 Delivery Package 1 TMA Grand Master main unit packed in a mandatory polyethylene container in a cardboard box Accessories in a metal box drill bits punchers pistons a wrench a drill bit and a puncher chuck paraffin block base molds accessories and tools for the assembly The size and the content of the box can vary according to your purchase order For further information on the basic acc...

Page 13: ...Microsoft Excel or OpenOffice on the control computer 2 4 Installing and Configuring TMA Grand Master Hardware Warning Only qualified personnel may install TMA Grand Master and perform the initial start up procedure 3DHISTECH Service technicians install and configure TMA Grand Master and hand it over to you in operating condition 2 5 Transporting the TMA Grand Master Main Unit Warning If you need ...

Page 14: ...side plates of the main unit Figure 4 Transporting handle 4 Place the device into the designated cardboard box onto the bottom protective foam 5 Arrange protective padding on the four top corners 6 Pack the accessories into their box 7 Put the main unit and the accessory box to their designated places in the road box 8 Close the box and tape it April 8 2014 Rev 1 3DHISTECH Ltd 14 79 ...

Page 15: ...requisite and temporary files 500 GB for saving the TMA database and for storing digital slides 3 2 TMA Grand Master Software Installation Important 3DHISTECH service technicians perform the installation and configuration of the TMA Grand Master software application The following installation procedure is for information purposes only follow the below steps only if you need to re install the softw...

Page 16: ... TMA Grand Master USB driver CDM driver Camera driver VRmagic 2 Launch the TMAGrandMaster_2 1_RTM exe file that you received on a 3DHISTECH Installation Disk or downloaded in a compressed file 3 Follow the instructions in the installation wizard 4 Select the license type browse for the license file or select HASP dongle April 8 2014 Rev 1 3DHISTECH Ltd 16 79 ...

Page 17: ... Application 5 Accept the End User License Agreement and click Next 6 Choose the installation folder for the TMA Grand Master software application Click Browse for locating a different folder than the default one then click Next to continue April 8 2014 Rev 1 3DHISTECH Ltd 17 79 ...

Page 18: ...tion of TMA Grand Master Software Application 7 Create the Start menu folder 8 The installer automatically downloads the necessary prerequisite files Click Install to start the installation of prerequisites April 8 2014 Rev 1 3DHISTECH Ltd 18 79 ...

Page 19: ...tall to continue with the installation of the TMA Grand Master application 10 After completing the installation of TMA Grand Master click Finish to close the wizard The relating User s Guide can be opened if you activate the Show User s Guide option in this window April 8 2014 Rev 1 3DHISTECH Ltd 19 79 ...

Page 20: ...ing the user documentation will be opened automatically Otherwise a pop up window is displayed offering you to download the application Click Yes and the website is opened in your browser with the download link of the product 11 After finalizing the installation the computer must be restarted Click Yes to finish the installation April 8 2014 Rev 1 3DHISTECH Ltd 20 79 ...

Page 21: ...tion on the control computer 2 Switch off the TMA Grand Master 3 Turn the control computer and the monitor off 4 2 Starting the TMA Grand Master Application You can start the program by double clicking onto the program icon of the desktop Warning If you start the software but the hardware is turned off a warning message appears Switch on the main unit then click Retry in the message box Warning If...

Page 22: ...TMA Grand Master software If you start the application for the first time a New Project window is displayed in which you must enter a name for the project If you already have worked on projects previously and you want to create a new project click New and if you want to load a project that has been saved previously click Load in the Project panel that is located at the top right corner of the appl...

Page 23: ...ating Date Range and or Diameter filters When writing the name of the project to be loaded suggested projects appear on the list according to the entered text string According to the database driven project handling each time you restart the software even without saving the current process of the actual project before exiting all the data is loaded automatically to restore the previous state April...

Page 24: ...nd processing method of blocks the normal view includes thumbnails of all recipient tray positions and as for donor blocks the selected tray is displayed in its full capacity The other view mode helps users to identify blocks and their statuses more easily Click at the top of recipient blocks panel and at the right end of donor blocks panel to switch to this view April 8 2014 Rev 1 3DHISTECH Ltd 2...

Page 25: ...nto a slot on a donor block tray its image will appear on the left section of the donor blocks panel at the bottom of the main application window At the donor panel a separator can be dragged sideways and is a used for dividing donor block panel to display TMA block thumbnails that are being processed and that are finished 4 3 1 Main Toolbar The main toolbar of the TMA Grand Master software is loc...

Page 26: ...king on extra hard tissues for example not decalcified may end up breaking the puncher needle Important To ensure the good quality of recipient blocks make sure that the top surfaces of both recipient and donor blocks are parallel to the plastic bottom of the cassettes and there are no dents or cavities in the paraffin layer If any defect is visible cut the top layer of the block to make it even o...

Page 27: ...n For cleaning blocks use regular 37mm size blocks only To avoid contamination cleaning block are used before each PCR sampling A cleaning block is a virgin recipient block from which paraffin core is extracted and placed back with the puncher hence cleaning its surface Upon selecting the cleaning block on the user interface an automatic layout is generated based on the size of the puncher in use ...

Page 28: ... cleaning spots depending on the puncher diameter are the following Puncher diameter Number of cleaning spots 0 6mm 252 1mm 144 1 5mm 72 2mm 50 NOTE It is recommended that you use punchers of larger diameters 1 5 or 2 mm for PCR extraction as smaller tissue cores for example 0 6 and 1 mm in diameter may bind to surfaces other than of the PCR tube due to electrostatic charge 4 4 3 Inserting a block...

Page 29: ...ID of the corresponding tray is marked with green also the slot is lit for easier identification 4 The door opener button turns green button status is shown at the right side of the main toolbar The light pulsates for about 10 seconds and it is possible to open the door within this time frame countdown is displayed in place of the button 5 Push the door opener button to open the door 6 Press down ...

Page 30: ... the button next to the image of the specific block pairs 3 A donor recipient block holder column turns to the loading position with its appropriate side 4 The door opener button turns green The light pulsates for about 10 seconds and it is possible to open the door within this time frame countdown is displayed by a icon at button area 5 Push the door opener button to open the door 6 Press down th...

Page 31: ... to change drill bits punchers and pistons to match the hole diameter of a defined layout 1 Start the TMA Grand Master application then click the button at the main toolbar 2 According to the appearing message on your screen follow the steps to change the tools of the same size both for the puncher and the drill bit 3 Open the tool exchanger compartment door Figure 7 Tool compartment April 8 2014 ...

Page 32: ...e about two turns 360 720 degrees then remove the drill bit from the drill chuck Figure 9 Drill chuck 6 Insert the drill bit you want to use into the drill chuck and push it inwards as much as you can 7 Hold the front cog wheel firmly and tighten the rear cog wheel clockwise Make sure with the help of the tool that the upper cog wheel is secured firmly 8 Insert the drill chuck into its position an...

Page 33: ...Puncher chuck 11 First insert the new piston in the puncher chuck then insert the puncher into the puncher chuck matching the size of the piston Tighten the rear cog wheel holding the front cog wheel firmly 12 Insert the puncher chuck into its position and fix it with the puncher chuck locking lever Ensure that the two cog wheels motor and puncher chuck are aligned exactly and move the piston into...

Page 34: ...up to twelve identical TMA blocks by taking out one tissue core sample and inserting it into each recipient block Then you can either create several slides from the TMA blocks or you can just keep one of the TMA blocks as a backup When you are filling the recipient block from up to sixty donor blocks maximum number of donor blocks the digital camera of TMA Grand Master gives you an image of each d...

Page 35: ...ed in its position For more information see section 11 Cassette and Block Dimensions 5 2 Working with Recipient Block Layouts 5 2 1 Creating a recipient block layout 1 To create a layout click the arrow or at the upper section of the Layout button next to the recipient block image Note that there is a icon at the bottom of this button and if you click it the layout will be deleted April 8 2014 Rev...

Page 36: ...racters 4 When working with special blocks that have different sizes than displayed by default activate the Custom Block Size function and set the correct measurements 5 Select a value at the Tool Diameter section for the puncher and the drill bit sizes 6 Select the size of the Gap between the holes 7 Select the number of Columns and Rows 8 Pattern alignment can be set at the Alignment pane of the...

Page 37: ...g the mouse button pressed select the unwanted area on the layout Figure 12 Layout pattern 10 When finished creating a layout click Save 11 To create an additional layout click New 12 If you do not wish to create further layouts click Exit Important The table below shows the maximum number of holes can be drilled into a paraffin block depending on hole sizes Paraffin Block Size mm Hole Sizes mm Ma...

Page 38: ...next to the block image OR Open either the Layout Editor window Select the layout you want to delete from the drop down menu and click Delete NOTE You cannot delete a layout if it has already been used in a TMA project If you do not wish to delete further layouts click Exit to close the window 5 3 Inserting Recipient Blocks 1 Switch on the TMA Grand Master main unit the control computer and the mo...

Page 39: ...osition 4 Select a layout for the recipient block a Click the image of the recipient block for which you want to add a layout b Select a pre defined layout from the Select Layout drop down list in the Layout Editor window then click Use this layout Note that only those layouts appear on the list which include spots of same diameter as set for tools c If the necessary layout is not yet created desi...

Page 40: ...re the software makes it available for you to group identical blocks To create groups click the tab below the preview of the recipient blocks then select the desired group number that is also marked by a specific color for the easier identification e To create several blocks with different layouts repeat steps a c Important If loading a PCR cassette in the tray make sure to insert the necessary am...

Page 41: ...w the preview image is displayed by default If the label is upside down click Rotate 3 The Donor block ID must be entered into the text field below the donor block image After typing an ID into the Donor ID field hit Enter or click the button next to the label field to accept the ID After entering the donor block ID and hitting enter or clicking the button the label area disappears automatically C...

Page 42: ...toolbar After setting the proper type of barcode in the Barcode window click the Barcode button below the donor block preview image 5 After the barcodes of donor or recipient blocks are identified they are automatically displayed both in the Recipient Block ID and Donor Block ID fields If barcode reading had not been previously set the Barcode window appears in which you can specify the barcode ty...

Page 43: ... button on the left of the donor block image is automatically displayed if a PCR cassette is properly inserted to its slot on the donor tray selected to work on NOTE The first tube position must always be on the left bottom of the cassette and the cover plate tab faces to the left side of the device After you have activated the PCR function by clicking the PCR button make sure to insert cleaning b...

Page 44: ...irst click the PCR button on the left side of the donor image The number of PCR markers placed on the donor block appears in the PCR button Place TMA markers on desired areas of the donor block where tissue core should be extracted from then click the position of the recipient block layout that you want to fill with the core sample Important Each donor position has its adherent PCR position for ex...

Page 45: ...TMA Grand Master inserts each core into the next available spot and proceeds from left to right and from top to down order in the layout grid of the TMA block If you have activated the new view for donor blocks the block on which you have selected a core to be transferred and clicked Start the thumbnail of that specific block will be moved to the back end of the block queue NOTE You can interrupt ...

Page 46: ...xt to the block Accordingly the process state is also displayed on the blocks represented by gear icons of the same color as on the recipient layout image Blue marked but processing has not started yet Green process is started and scheduled Yellow process is running 5 If punching is completed to all the selected donor blocks remove the completed donor blocks from the tray as described in section 4...

Page 47: ...f the donor block represents the status of the door of the device If this icon pulsates in red and green it means that there is a donor block from which all of the selected cores are extracted In this case you must click the lock button first on the GUI then the button on the door to open it The lock automatically turns green after a process is finished Each time after you remove or replace a bloc...

Page 48: ...llowing Exit the TMA Grand Master application by clicking Exit If you have exported data and you want to exit the application click Yes in the displayed window Turn the main unit and the power supply off Clean the main unit For more information see section 6 2 Cleaning Tasks 5 6 Slide overlay With the Slide overlay function you can refine the position of the digitized slide image to match the posi...

Page 49: ... 1 User s Guide 5 Using TMA Grand Master If locating a slide image on a CaseCenter server type in the URL then click CC connect Login to CaseCenter with your user name and password April 8 2014 Rev 1 3DHISTECH Ltd 49 79 ...

Page 50: ...n the folder tree then left click on the slide to import it NOTE Make sure that Pannoramic Viewer is the default program to open a slide from CaseCenter Flip slide image if needed by selecting one of the options Flip horizontal or Flip vertical April 8 2014 Rev 1 3DHISTECH Ltd 50 79 ...

Page 51: ... image drag rotate zoom to correspond with the block image Place two reference points on the block image and refine their positions on the slide image If misplaced you can delete any of them by clicking the Clear reference points button April 8 2014 Rev 1 3DHISTECH Ltd 51 79 ...

Page 52: ...ransparency level of the JPG image layer by moving the Opacity slider This allows you to set how much the slide image should obscure the donor block image If you check the Show markers checkbox the TMA markers will be displayed You can select the marker category you want displayed by choosing one of the diameter values 600 1000 1500 or 2000 from the Markers diameter drop down menu April 8 2014 Rev...

Page 53: ...he image below Color RGB code Red 255 0 0 Yellow 255 255 0 Green 0 128 0 Blue 0 0 255 For other colors and their RGB values please follow this link http www febooti com products iezoom online help html color names 16 color chart html After selecting the marker diameter click Finish to get back to the Puncher window In the main window confirm marker positions by clicking on them Close spots will be...

Page 54: ...donor block data If you have finished the transfer process from donor to recipient block s you can export block data to a spreadsheet file separate worksheets will be created within the file for each block If you want to fill other sample cores into the blocks at another time these files can be used and to which donor block data can be appended Depending on the mode you operate TMA Grand Master in...

Page 55: ...and you want to save block related data click the Export button in the main toolbar and the Custom Export window appears Select a project from the Project drop down list You can narrow or filter the list by activating and specifying tool diameter or date at the relevant fields April 8 2014 Rev 1 3DHISTECH Ltd 55 79 ...

Page 56: ...eme you can custom define a record set from the SQL database of the related project NOTE Make sure to select appropriate fields when creating a new scheme Database records are freely selectable and erasable from the set The MedicalInfos record is empty by default if there is no data imported yet Save scheme by entering a name to the Scheme name field and clicking Save and Use April 8 2014 Rev 1 3D...

Page 57: ...er 2 Moving blocks from the Recipient Blocks field to the Coherent Blocks field one by one by clicking creates separate databases for each block Click the button to move all recipient blocks to the Coherent Blocks field April 8 2014 Rev 1 3DHISTECH Ltd 57 79 ...

Page 58: ... on the Group items and finally click the button but if you choose to create separate for each of the selected groups click 3 Type in a name for each database into the Database name field 4 It is available for you to import an existing database to which you can append data Click Select File at the Import File Name section then browse for the file April 8 2014 Rev 1 3DHISTECH Ltd 58 79 ...

Page 59: ... export data to a new file will be generated by the application browse for the folder by clicking Browse at the Database Path and Type section and type in a file name 7 Select the desire file format XLS XLSX ODS NOTE Open file with the appropriate software for example use Excel to open file in XLS or XLSX or OpenOffice Calc to open file in ODS format 8 Click Save to create the output file or Cance...

Page 60: ... ID fields of TMA Block ID column contains automatically generated names that can be recognized and used by the TMA Module TMA Block Name as an extra column on the sheet contains Recipient names may include special characters The depth values related to the specific donor blocks are listed under the Donor Core Height column The Donor Block Images column lists donor image links images are stored in...

Page 61: ...eir positions in the layout The third sheet contains recipient block related data table where the Donor Block IDs are shown according to their positions in the layout Tip If you want to import the exported data to TMA Module you need to create a worksheet called Slides including stain types recipient block IDs and slide names April 8 2014 Rev 1 3DHISTECH Ltd 61 79 ...

Page 62: ...can import an existing file to which additional data will be appended Click Select File then locate file 2 Type a database name at the relevant field if you want create a new file 3 Click Browse to set the destination folder of the file and select the file type NOTE When opening XLS files in OpenOffice links to external images cannot be opened 4 Click Save to create the output file or Cancel to ex...

Page 63: ...ick Import at the main menu bar of the application window 2 Click Browse in the Import window to search for the data file to be imported If the ID of the donor block loaded into the device exists in the imported database the data set of the specific donor block can be appended to the database April 8 2014 Rev 1 3DHISTECH Ltd 63 79 ...

Page 64: ...elected data sheet can be modified with the Merge or the Replace function The imported data are stored in the MedicalInfos data sheet that can be selected as a record when exporting 4 Select Replace to overwrite existing data with the new ones April 8 2014 Rev 1 3DHISTECH Ltd 64 79 ...

Page 65: ...rmation to the existing data set select Merge so additional columns will be inserted into the sheet Donor Block ID will become Donor Name no other data will be overwritten 6 Differences in the data for example if donor data of a specific block do not match name age etc are highlighted with red in the window The database cannot be modified manually but can be saved with the Save for Editing option ...

Page 66: ...A Grand Master 5 9 Restore medical information database To restore medical information database therefore omitting all the data during handling the project before exporting click Settings at the main toolbar April 8 2014 Rev 1 3DHISTECH Ltd 66 79 ...

Page 67: ...htly moistened piece of cloth You may also use detergent Wipe off oil or grease contamination traces from the surface of the main unit with a cotton swab dipped into acetone but keep away acetone ethanol from mirrors and lenses It is forbidden to clean mirrors and lenses with ethanol acetone The user should prevent any kind of fungal contamination on the opto mechanical parts of the TMA Grand Mast...

Page 68: ... compartment do the following 1 Switch off the TMA Grand Master device 2 Pull out the trash container 1 Figure 13 Trash container 3 Release lock by pulling out the lever 1 at the inner panel and move it to the marked position 2 Figure 14 Opening the service compartment door 4 Grab the handles and open the compartment door 5 Clean the compartment area 6 Close the door then lock the lever April 8 20...

Page 69: ...r cable 2 The fuse compartment is located next to the main power supply switch at the back side of the TMA Grand Master 3 Release lock 1 by pushing the lever to the right so the insert 2 can be pulled out Figure 15 Releasing the lock of the fuse compartment 4 Remove insert from the compartment Figure 16 Removing the fuse compartment April 8 2014 Rev 1 3DHISTECH Ltd 69 79 ...

Page 70: ...minated Tray or Touch Sensor Surface If during initialization after switching on the TMA Grand Master device the program detects possible contamination at the surface of the F donor block tray between the positions F9 and F10 or of the touch sensor the following message appears on the screen Click Yes then follow the instructions regarding cleaning the tray surface After you finished cleaning the ...

Page 71: ...TMA Grand Master According to the instructions in the following message by using a dry and clean cloth gently rub the bottom surface of the touch sensor sensor is marked with red in Figure 18 Figure 18 Touch sensor April 8 2014 Rev 1 3DHISTECH Ltd 71 79 ...

Page 72: ...d F10 or the touch sensor is contaminated What to do Clean the surface of the tray then the touch sensor at the specified areas For more information see section 6 4 Contaminated Tray or Touch Sensor Surface Block Image in the Application is of Poor Quality Cause Imaging errors What to do Contact 3DHISTECH support Puncher Falls Out During Punching Cause The puncher needle is detached from the colla...

Page 73: ...he computer For instance write access must be granted to C ProgramData 3DHISTECH TMAGrandMaster folder its sub folders files and in addition enable the software to modify registry logs Block image and label area not visible Cause Problem with preview camera COM driver registry entry is missing Solution Restart GTMA software application If the problem still persists try to reinstall it April 8 2014...

Page 74: ...th of the block is 13 5 mm The smaller size 7 5 mm in depth means the paraffin thickness from the upper edge of the plastic cassette The height of paraffin blocks in parentheses means their total depth together with the plastic cassette Warning Do not use paraffin blocks which dimension values are higher than 24mm W x 37mm H x 10mm D otherwise the drilling and punching heads may be damaged If the ...

Page 75: ...512 44 352 Max 3 3 approximate values 9 2 Accessories Accessory Dimensions in mm Number of items Base mold for paraffin blocks 37 24 7 5 3 Drill bit Ø 0 6 Ø 1 0 Ø 1 5 Ø 2 0 2 2 2 2 Puncher Ø 0 6 Ø 1 0 Ø 1 5 Ø 2 0 3 3 3 3 Puncher chuck and Drill bit chuck N A 2 Piston Ø 0 6 Ø 1 0 Ø 1 5 Ø 2 0 1 1 1 1 For Drill bits Punchers and Pistons there are four distinctive color markings for each different siz...

Page 76: ...llion Pixel 9 4 Ambient Conditions Condition Suitable Range Shipment packed Ambient temperature 40 C to 70 C Storage Ambient temperature 10 C to 40 C Maximum relative air humidity 75 at 35 C Operation Ambient temperature 10 C to 40 C Maximum relative air humidity 75 at 35 C Maximum altitude 2000 m Air pressure range 500 hPa to 1060 hPa Degree of pollution 2 April 8 2014 Rev 1 3DHISTECH Ltd 76 79 ...

Page 77: ...e IP 20 Electrical safety in compliance with EN 61010 1 IEC 61010 1 and taking CSA UL regulations into account Over voltage category II Radio interference suppression in accordance with EN 55011 class B Noise immunity in accordance with EN 61326 2 6 2005 Main unit line input voltage 24 V DC 1 V Mains supply voltage 90 240V Mains frequency 50 60 Hz Power rating 300W April 8 2014 Rev 1 3DHISTECH Ltd...

Page 78: ...TMA Grand Master 2 1 User s Guide Related documents Related documents Pannoramic Viewer 1 15 3 User s Guide TMA Module 1 16 User s Guide April 8 2014 Rev 1 3DHISTECH Ltd 78 79 ...

Page 79: ... 8 9 27 28 34 40 43 44 45 47 48 Punch 9 12 26 27 28 29 31 33 34 36 41 45 46 53 72 74 75 R Recipient block 8 9 27 29 30 34 35 38 39 40 43 44 45 46 54 60 61 67 Research project 9 S Slide 4 8 29 34 44 48 49 50 51 52 61 T The Donor Block Images column lists donor image links images are stored in separate folders at the same location as the spreadsheet file 60 TMA 8 9 13 52 60 61 TMA Grand Master 6 9 1...

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