WATERS CORPORATION TQ, Руководство оператора

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Ion optics
December 6, 2012, 71500126802IVD Rev. C 25
Ion optics
The instrument’s ion optics operate as follows:
1. Samples from the LC or Intellistart fluidics system are introduced at
atmospheric pressure into the ionization source.
2. The ions pass through the sample cone into the vacuum system.
3. The ions pass through the transfer optics, to the first quadrupole where
they are filtered according to their mass-to-charge ratios.
4. The mass-separated ions pass into the T-Wave™ collision cell where
they either undergo collision-induced dissociation (CID) or pass to the
second quadrupole. Any fragment ions are then mass-analyzed by the
second quadrupole.
5. The transmitted ions are detected by the photomultiplier detection
system.
6. The signal is amplified, digitized, and sent to the MassLynx mass
spectrometry software.
Ion optics overview
Sample cone
Isolation valve
T-Wave collision
cell
Z-Spray ion source Quadrupole 1
(MS1) Quadrupole 2
(MS2) Detector
Conversion dynode Sample inlet Transfer optics