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1
– Introduction
Thermo Scientific
Product Manual for the ERS 500 Suppressor
Page 12 of 84
031956-11
For Research Use Only. Not for Use in Diagnostic Procedures.
, the water regenerant undergoes electrolysis to form hydroxide ions on the
cathode surface along with hydrogen gas while hydronium ions are formed in the anode surface
along with oxygen gas. In the Anion Suppressor, cation exchange materials such as screens,
membranes and resins allow hydronium ions to move from the anode chamber into the eluent
chamber to neutralize the hydroxide eluent. Sodium ions or eluent or sample counter-ions in the
eluent are driven by the applied electric potential towards the cathode and combine with the
hydroxide ions generated at the cathode to form sodium hydroxide waste. Hydronium ions can
also travel all the way to the cathode to form water, thus effecting suppression of the eluent and
conversion of the analyte to typically a more conductive acid form.
Figure 2
AutoSuppression with the Dionex AERS 500
The Dionex Electrolytically Regenerated Suppressor for External Water Mode (Dionex ERS
500e) is optimized for use in the external water mode. The Dionex ERS 500e hardware design is
similar to the Dionex ERS 500 hardware design from a sealing perspective and is optimized for
minimal band dispersion and improved flow performance. The Dionex ERS 500e uses the same
ion exchange membranes, screens, and resin materials as the standard Dionex ERS 500
suppressor. The Dionex ERS 500e is configured with a parallel regenerant flow to facilitate easy
supply and removal of regenerant and waste from the regenerant compartments making it
suitable for external water applications, as well as applications where organic modifiers (up to
40%) are present in the eluent or sample. The Dionex ERS 500e is required for applications
where borate is used as an eluent.
The Dionex ERS 500e (2 mm) suppressor is compatible with MS detection; the suppressor has
been designed to have minimal interference for MS applications and is designed for operation in
Dionex AERS 500 in AutoSuppression Mode