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How to Create Tablets with the DTP 25

Tools and Materials Needed

• Raw material formulation
• DTP 25

•  Safety goggles
•  Disposable latex/rubber gloves (for food grade products and to protect hands from grease)
•  Hairnet and/or beard net (food grade products only)
•  Sterile shoe covers (food grade products only)

WARNING:

For personal protection while operating the DTP 25

, contain long

hair and do not wear loose jewelry.

Instructions

Note: Wear latex/rubber gloves (and appropriate food grade attire if applicable) during this
process.
1. Pour the dry materials into the Hopper.

1.1 Note: Ensure that the DTP 25

is unplugged from the electrical outlet.

2. Open the front Perspex door and rotate the Hand Wheel in the direction indicated by the arrow
located on the Motor.

2.1 Note: Always manually operate the DTP 25

for one rotation before running the

machine.

3. Plug in the DTP 25

to an electrical outlet.

4. Press the green button (ON) to start operation and the red button (OFF) to stop.

Содержание DTP 25

Страница 1: ...We don t just sell machines we provide service DTP 25 Tablet Press User Manual...

Страница 2: ...any retrieval system of any nature without prior permission except for fair dealing under the Copyright Designs and Patents Act 1988 or in accordance with the terms of license issued by the Copyright...

Страница 3: ...safety goggles Wear disposable latex rubber gloves Wear a hairnet food grade products only Wear a beard net if needed food grade products only General Hazards Be aware of risk of entanglement and pin...

Страница 4: ...ing motor operation immediately press the Emergency Stop button turn the isolator switch and unplug CAUTION This signals potential risk for damage to the machine or other parts Prop 65 Statement for C...

Страница 5: ...Workstation for the Machine 10 Positioning the DTP 25 12 Manual and Electrical Controls 14 Settings and Adjustment 17 Maintenance 23 General Maintenance Prescriptions 23 Lubrication 23 Dismantling fo...

Страница 6: ...6 1 2 3 4 5 6 7 9 10 11 13 14 15 16 17 18 19 20 12 8...

Страница 7: ...ave Pressure Adjustment 8 Eccentric Sheave Inner Strap 9 Upper Drift Pin Assembly 10 Upper Punch 11 Boot 12 Lower Drift Pin Assembly 13 Lower Drift Pin Assembly Cogs Adjustment Plate 14 Lower Drift Pi...

Страница 8: ...ction of 1 500 tablets per hour With an emphasis on convenience and accessibility this tablet press is a cost effective solution for users who seek moderate quantities of tablet production The purpose...

Страница 9: ...if you prefer LFA can provide training via phone for all customers who call the office To set up a training call or email your local LFA office UK Phone 44 0 0345 165 20 25 Email support uk lfamachin...

Страница 10: ...net and or beard net food grade products only Sterile shoe covers food grade products only The Appropriate Workstation for the Machine Find a stable workspace surface that supports the DTP 25 s 332 kg...

Страница 11: ...11 The shipping crate will contain the following 1 The assembled DTP 25 2 The Tooling already installed 3 The De Jamming Bar...

Страница 12: ...ne from the shipping container and placing it in the workspace Transporting the DTP 25 Tools and Materials Needed Engine hoist Adjustable wrench Instructions 1 Open the top panel of the machine and se...

Страница 13: ...he anti vibration feet from the pallet 5 Loosen the bolts that secure the anti vibration feet with an adjustable wrench 6 Rotate the anti vibration feet until they are at an adequate height and tighte...

Страница 14: ...Top Cam guides the punches movement The Hopper holds the dry materials that will be compressed The Boot moves the materials from the Hopper to the Tooling and ejects the tablets The Die defines or mol...

Страница 15: ...is operated by the motor the Gearbox initiates the movement of the Top Cam which withdraws the Upper Punch from the Die Compressing the Powder After the powder is filled in the Tooling the Top Cam dr...

Страница 16: ...do not wear loose jewelry Instructions Note Wear latex rubber gloves and appropriate food grade attire if applicable during this process 1 Pour the dry materials into the Hopper 1 1 Note Ensure that...

Страница 17: ...rom the machine Ejection Height When the Upper Punch is fully lifted the Lower Punch in its highest position should be flush with the Die If the Lower Punch is above or below the Die s face it will af...

Страница 18: ...e ejection height adjustment locking screw with an Allen key 5 Insert an Allen key into one of the ejection height adjustment s holes and turn to adjust 5 1 Note Turn clockwise to raise the ejection h...

Страница 19: ...ns Note Wear latex rubber gloves and appropriate food grade attire if applicable during this process 1 Produce a test tablet to determine how the Tooling should be adjusted 2 Open the front Perspex do...

Страница 20: ...roducts and to protect hands from grease Hairnet and or beard net food grade products only Sterile shoe covers food grade products only Instructions Note Wear latex rubber gloves and appropriate food...

Страница 21: ...isposable latex rubber gloves for food grade products and to protect hands from grease Hairnet and or beard net food grade products only Sterile shoe covers food grade products only Instructions Note...

Страница 22: ...ustment 3 Raise or lower the pressure adjustment by hand to change the pressure 4 Ensure that the locking bar is in between a set of teeth on the Eccentric Sheave Strap and rotate the pressure adjustm...

Страница 23: ...and after machine operation If the machine is not used for more than a week place the Tooling in an airtight container and cover in lubricant Lubrication Regularly greasing your machine is vital to pr...

Страница 24: ...g Cam s sides 1 1 Note Be sure to lubricate the Boot Timing Cam runner and the Lower Drift Pin Assembly Timing Rod runner 2 Lubricate the points at which the base and Upper Drift Pin Assembly meet 3 L...

Страница 25: ...25 4 Lubricate the brass part in between the Eccentric Sheave Strap Pressure Adjustment and Eccentric Sheave...

Страница 26: ...prolonged period of time NLGI Grade 2 Lower Drift Pin Assembly The point at which the Lower Drift Pin Assembly and base meet Apply in the following situations a after every 50 000 tablets b after a d...

Страница 27: ...ally due to wear and tear some parts of the DTP 25 will need to be removed for repair and replacement To prevent any delays in your tablet production it is best practice to keep extra parts just in ca...

Страница 28: ...ed it is necessary to change the Tooling To buy new Tooling from LFA simply go to https www lfatabletpresses com products tablet press tooling Instructions Note Wear latex rubber gloves and appropriat...

Страница 29: ...screws securing the back Perspex panel with an Allen key 4 Remove the back Perspex panel from the machine 5 Remove the circlip on the Boot Timing Bar Extender 6 Remove the pin on top of the Boot with...

Страница 30: ...et aside 7 Pull down the Boot Bolt and Spring from the Boot 8 Lift up the Boot and disengage it from the Boot Timing Bar Extender s pin 9 Loosen the four bolts underneath the Ejection Tray with an All...

Страница 31: ...rs or pliers 14 Remove the righthand Perspex panel by unscrewing its four corner bolts with an Allen key 15 Loosen the Die s screw on the righthand side of the Base Plate 16 Slightly increase the ejec...

Страница 32: ...ower Punch by hand 20 1 Note If you cannot remove by hand carefully use grippers or pliers Note To help ensure that the Die is inserted correctly LFA recommends using an Insertion Ring You can order t...

Страница 33: ...tate the Hand Wheel to see that the new Upper Punch smoothly enters the new Die bore and that the new Upper Punch is seated firmly in the Upper Drift Pin Assembly 28 Reattach the Ejection Tray with an...

Страница 34: ...r beard net food grade products only Sterile shoe covers food grade products only WARNING To prevent any potential personal injury ALWAYS unplug the DTP 25 from the electrical outlet when replacing pa...

Страница 35: ...screws securing the back Perspex panel with an Allen key 4 Remove the back Perspex panel from the machine 5 Remove the circlip on the Boot Timing Bar Extender 6 Remove the pin on top of the Boot with...

Страница 36: ...36 7 Pull down the Boot Bolt and Spring from the Boot 8 Lift up the Boot and disengage it from the Boot Timing Bar Extender s pin...

Страница 37: ...Timing Bar Extender s pin into the new Boot and resecure it with circlip pliers 13 Turn the Hand Wheel for one operation cycle to ensure that the machine runs smoothly before plugging it in and turnin...

Страница 38: ...se Plate The Boot Teflon Pad is designed to wear over time to avoid damaging more expensive parts Instructions Note Wear latex rubber gloves and appropriate food grade attire if applicable during this...

Страница 39: ...screws securing the back Perspex panel with an Allen key 4 Remove the back Perspex panel from the machine 5 Remove the circlip on the Boot Timing Bar Extender 6 Remove the pin on top of the Boot with...

Страница 40: ...40 7 Pull down the Boot Bolt and Spring from the Boot...

Страница 41: ...41 8 Lift up the Boot and disengage it from the Boot Timing Bar Extender s pin 9 Turn over the Boot and remove each screw on the teflon pad with an Allen key 10 Remove the Boot Teflon Pad...

Страница 42: ...h needle nose pliers 15 Insert the Boot Timing Bar Extender s pin into the new Boot and resecure it with circlip pliers 16 Turn the Hand Wheel for one operation cycle to ensure that the machine runs s...

Страница 43: ...pper Punch at a low point Adjust the starting position so that the Upper Punch is at the highest point Knocking sounds coming from machine The Upper Drift Pin Assembly is slightly off Adjust the Upper...

Страница 44: ...filling Check that there is not a buildup of powder between the Lower Punch and the Die Then check that the Lower Drift Pin Assembly has enough clearance to drop through the hole in the base There are...

Страница 45: ...et capping Shattered tablets The Boot Timing Bar and the Boot are not adjusted properly Adjust the Boot Timing Bar by loosening tightening its bolt and moving it Air is becoming trapped in the tablet...

Страница 46: ...bber gloves for food grade products and to protect hands from grease Hairnet and or beard net food grade products only Sterile shoe covers food grade products only Instructions Note Wear latex rubber...

Страница 47: ...e the back Perspex panel 3 Open the front Perspex door 4 Remove the Boot Timing Bar Extender from the Boot with circlip pliers 5 Remove the pin on top of the Boot with small needle nose pliers 6 Remov...

Страница 48: ...ball ends Disposable latex rubber gloves Bagless vacuum 3 clean cloths Potable water Bowl of warm soapy water nothing abrasive Sanitizer e g Member s Mark Commercial Sanitizer Hairnet and or beard net...

Страница 49: ...crews securing the Hopper with an Allen key CAUTION To prevent the Hopper from falling and becoming damaged hold it in place while its four screws are being removed 4 Remove the Hopper from the back P...

Страница 50: ...ner screws securing the back Perspex panel with an Allen key 6 Remove the back panel from the machine 7 Remove the circlip on the Boot Timing Bar Extender 8 Remove the pin on top of the Boot with smal...

Страница 51: ...the Boot Bolt and Spring from the Boot 10 Lift up the Boot and disengage it from the Boot Timing Bar Extender s pin 11 Disassemble the Boot by loosening the screws on the top and bottom of the part wi...

Страница 52: ...rs or pliers 15 Remove the righthand Perspex panel by unscrewing its four corner bolts with an Allen key 16 Loosen the Die s screw on the righthand side of the Base Plate 17 Slightly increase the ejec...

Страница 53: ...Remove the Die from the Base Plate 20 Remove the bolt that locks the Lower Punch with an Allen key 21 Remove the Lower Punch by hand 21 1 Note If you cannot remove by hand carefully use grippers or p...

Страница 54: ...eaning tooling use non abrasive cleaning equipment such as a soft pipe cleaner and soft cloth 28 Dry part immediately after it is cleaned and rinsed 29 Sanitize part with a clean cloth 30 Repeat steps...

Страница 55: ...hreaded Cam Clean in machine Clean in machine Clean in machine Clean in machine Clean in machine Clean in machine Clean in machine Clean in machine Lower Drift Pin Assembly Remove from machine Remove...

Страница 56: ...om lubricant Hairnet and or beard net food grade products only Sterile shoe covers food grade products only Instructions Note Wear latex rubber gloves and appropriate food grade attire if applicable d...

Страница 57: ...Drift Pin Assembly and DTP 25 base Environmental Conditions It is important that the environment in which you store the DTP 25 has the appropriate temperature and relative humidity levels These two en...

Страница 58: ...s as the vehicle or medium for a drug or other API Fill depth The amount of space that the powder can flow into in the Die Formulation Powder mix of the excipient and the API that is compressed to mak...

Страница 59: ...fill depth and ejection height They are located in the Lower Drift Pin Assembly Description of DTP 25 Parts Lower Assembly Timing Cam The Lower Assembly Timing Cam moves the Lower Assembly Timing Rod...

Страница 60: ...essing It fills the Die bore with the dry granular material and moves the finished tablet out of the Die before refilling it with the next batch of materials Hopper The Hopper is the funnel that holds...

Страница 61: ...t Pin Assembly to the Top Cam and also increases or decreases the Upper Punch pressure Lower Drift Pin Assembly Timing Rod The Lower Assembly Timing Rod raises the finished tablet out of the Die Lower...

Страница 62: ...e Top Cam Drive Shaft All other DTP 25 parts are connected to the Top Cam Drive Shaft As it is turned all the parts of DTP 25 move Base Plate The Base Plate is not only the mount for the Boot but also...

Страница 63: ...n the Upper Drift Pin Assembly and upper platform of the machine Lower Drift Pin Assembly Bushing Retainer The Lower Drift Pin Assembly Bushing Retainer reduces friction between the Lower Drift Pin As...

Страница 64: ...d 9336 1 Guanghua Electronic Mall Dunhua Electronic Materials Co Ltd Power Switch Shan Ho SC 88 3P 1 Shan Ho Emergency Stop Rockwell Automation 800FM MT44 ALM X02 1 Rockwell Automation Stop Button Roc...

Страница 65: ...er of dies 1 Max production capacity 1 500 hour Max diameter of tablet 25 mm Max thickness of tablet 8 mm Max fill depth 20 mm Max pressure 100 kN Number of filling stations 1 Double layered tablet No...

Страница 66: ...ccurring either a make mix more granular b check the Boot s base for damage or c clear the buildup with a paintbrush Occasionally check the Motor s temperature If it starts to overheat turn off the ma...

Страница 67: ...ns Diagram Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Dimensions DTP 25 1 0 4 X 15 00 415 00 465 0 25 00 71 00 620 00 478 00 84 00 936 00 1160 00 464 00 5...

Страница 68: ...68 DTP 25 Tooling Dimensions w w w l f a t a b l e t p r e s s e s c o m T D P I n t e r n a t i o n a l T o o l i n g S t a n d a r d D i m e n s i o n s...

Страница 69: ...69 DTP 25 Exploding Diagram Groups Group 1 Group 11 Group 12 Group 10 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Groups DTP 25 v2 1 0...

Страница 70: ...oding Diagram Group 1 Group 4 Group 3 Group 2 Group 5 Group 6 Group 7 Group 9 Group 8 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 1...

Страница 71: ...71 DTP 25 Exploding Diagram Group 2 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 2 DTP 25 v2 1 0...

Страница 72: ...72 DTP 25 Exploding Diagram Group 3 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 3 DTP 25 v2 1 0...

Страница 73: ...73 DTP 25 Exploding Diagram Group 4 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 4 DTP 25 v2 1 0...

Страница 74: ...74 DTP 25 Exploding Diagram Group 5 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 5 DTP 25 v2 1 0...

Страница 75: ...75 DTP 25 Exploding Diagram Group 6 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 6 DTP 25 v2 1 0...

Страница 76: ...76 DTP 25 Exploding Diagram Group 7 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 7 DTP 25 v2 1 0...

Страница 77: ...77 DTP 25 Exploding Diagram Group 8 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 8 DTP 25 v2 1 0...

Страница 78: ...78 DTP 25 Exploding Diagram Group 9 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 9 DTP 25 v2 1 0...

Страница 79: ...79 DTP 25 Exploding Diagram Group 10 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 10 DTP 25 v2 1 0...

Страница 80: ...80 DTP 25 Exploding Diagram Group 11 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 11 DTP 25 v2 1 0...

Страница 81: ...81 DTP 25 Exploding Diagram Group 12 Drawing Name Product Name Version Provided By LFA Machines www lfamachines com DTP 25 v2 Exploding Diagram Group 12 DTP 25 v2 1 0...

Страница 82: ...N01 Fan hole Power supply INV01 CP01 F01 02 RY01 PS01 MC01 TH01 TB 1 SW 4 1 FUSE FUSE SFKN SFKN 500V 500V 2 1 8 7 6 5 12 11 10 9 4 14 13 Drawing Name Product Name Version Provided By LFA Machines www...

Страница 83: ...on 00 23 1 No reverse rotation Auxiliary frequency source 00 35 3 AVI Maximum operating frequency 01 00 60Hz Start frequency 01 09 5HZ Frequency upper limit 01 10 599 00Hz Frequency lower limit 01 11...

Страница 84: ...7 0312 Security door stop SSW01 41 42 0303 Emergency stop EMO01 0304 PBL01 PBL02 0305 RY01 03 C7 0306 TH01 02 D2 0307 RY01 14 13 NO 03 C7 NO 02 D3 NO 03 E7 Security door stop SSW01 21 22 0309 Emergenc...

Страница 85: ...useful information about the DTP 25 and other tablet presses Use our online tools such as the Tablet Mix Calculator to help you in your formulation production or read our regularly published articles...

Страница 86: ...United Kingdom OX26 4PP 6601 Will Rogers Blvd Fort Worth Texas United States 76140 Business Parc Am Trippelsberg 92 D sseldorf Germany 40589 7F 5 No 2 Sec 2 Taiwan Blvd West Dist Taichung City 403 Tai...

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