COULTER HmX Hematology Analyzer, Справочное руководство

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PN 4237523A 4-16
SPECIFICATIONS/CHARACTERISTICS
INTERFERING SUBSTANCES
Reference Interval
Reference intervals (normal range) for the HmX Hematology Analyzer are divided into two
groups based on sex. The resulting minimum and maximum values of the laboratory normal
range are shown in Table 4.25.
4.8 INTERFERING SUBSTANCES
A salt of EDTA is the preferred anticoagulant. Beckman Coulter used K
3
EDTA for the data
collection and verification of claims. Use of other anticoagulants can yield misleading results.
The presence of certain interfering substances, as listed in this section, can also yield
misleading results.
WBC
Certain unusual RBC abnormalities that resist lysing, nucleated RBCs, fragmented WBCs, any
unlysed particles greater than 35 fL, very large or aggregated platelets as when anticoagulated
with oxalate or heparin, specimens containing fibrin, cell fragments, or other debris such as
pediatric and oncology specimens.
41, 42, 43, 44
RBC
Very high WBC count, high concentration of very large platelets, agglutinated RBCs, RBCs
smaller than 36 fL, specimens containing fibrin, cell fragments, or other debris such as
pediatric and oncology specimens.
45, 46
Hgb
Very high WBC count, severe lipemia, heparin, certain unusual RBC abnormalities that resist
lysing, or anything that increases the turbidity of the sample such as elevated levels of
triglycerides.
47
MCV
Very high WBC count, high concentration of very large platelets, agglutinated RBCs, RBC
fragments that fall below the 36-fL threshold, or rigid RBCs.
48, 49, 50, 51
RDW
Very high WBC count, high concentration of very large or clumped platelets as in blood
anticoagulated with oxalate or heparin, RBCs below the 36-fL threshold, two distinct
populations of RBCs, RBC agglutinates, or rigid RBCs.
52, 53, 54, 55
Table 4.25 Reference Intervals
Parameter Low High n
Retic-Male 0.6% 2.60% 100
Retic-Female 0.6% 2.60% 128