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Instruction Manual
Corning® MicroDEN® Platform
Table of Contents
Safety Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
2. Getting Started . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
3. Material Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
4. Setting up the Corning MicroDEN Unit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
5. Cell Seeding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
6. Differentiation Medium Loading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
7. Priming . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
8. Expansion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
9. Harvest (Day 6) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
10. Cleaning and Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
11. Troubleshooting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
12. Technical Specifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
13. Limited Warranty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
14. Equipment Disposal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Safety Information
To avoid personal injury while using the Corning® MicroDEN® unit:
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Take care while installing tubing; pinch points exist between the upper and
lower section of the pump door.
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Do not operate the pumps while pump doors are open
To avoid damage or malfunction of the MicroDEN unit:
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Ensure the unit is always placed on a firm, stable, and horizontal surface.
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Do not attempt to remove or repair the outer case of the unit.
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Never attempt to repair, disassemble, or modify this unit yourself, as tampering
with this product may result in injury or fire.
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Do not drop the unit or allow objects to fall onto it.
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Do not allow the unit to be submerged or immersed in liquid.
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Do not place any objects on top of this unit, and never stand or lean on the
unit. Failure to do so may cause the equipment to fall or collapse, which may
result in breakage and/or injury.
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Do not autoclave this unit.
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Do not perform the sterilization cycle of an incubator with the MicroDEN unit
inside.
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Do not use acetone to clean the unit.
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Always use the provided external power supply to power the MicroDEN unit.
Emissions and Interference – Warning Statements
FCC Part 15: This equipment has been tested and found to comply with the limits
for a Class A digital device, pursuant to part 15 of the FCC Rules. These limits
are designed to provide reasonable protection against harmful interference
when the equipment is operated in a commercial environment. This equipment
generates, uses, and can radiate radio frequency energy and, if not installed and
used in accordance with the instruction manual, may cause harmful interference
to radio communications. Operation of this equipment in a residential area is
likely to cause harmful interference in which case the user will be required to
correct the interference at his own expense.
ICES-003: CAN ICES-3(A)/NMB-3(A)
These warning statements apply to Class A products for business use:
This device complies with part 15 of the FCC Rules and with Industry Canada
license-exempt RSS standard(s).
Operation is subject to the following two conditions: (1) This device may not
cause harmful interference, and (2) this device must accept any interference
received, including interference that may cause undesired operation.
Cet appareil est conforme à la partie 15 de la réglementation de la FCC et à
Industrie Canada exempts de licence standard RSS (s).
