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during operation.
DANGER!
Oxygen causes a fire/explosion risk!
Users are responsible for performing their own safety assessment and obtaining expert advice on the
design of any system used to supply gases to the iCELLis 500+ control system.
RELEVANT ONLY WHEN USING OXYGEN: In the unlikely event of a tubing or connection failure,
oxygen may build up in and around the iCELLis 500+ control system. A means of independently
monitoring oxygen close to the equipment is highly recommended.
The monitoring system should be set up to prevent oxygen levels from reaching 24% or limits
recommended by local regulations. In the event of a rise in oxygen above this level, the supply should
be immediately shut down. The iCELLis 500+ control system can deliver oxygen up to 7 L/min. Oxygen
supply to the iCELLis 500+ control system is the user’s responsibility.
DANGER!
Risk of asphyxiation!
Carbon dioxide can cause asphyxiation. Ensure that the work space has adequate ventilation. Do not
place the system in an enclosed area. The iCELLis 500+ control system can deliver carbon dioxide up
to 1.5 L/min. Carbon dioxide supply to the iCELLis 500+ control system is the user’s responsibility.
DANGER!
Risk of asphyxiation!
Nitrogen can cause asphyxiation. Ensure that the work space has adequate ventilation. Do not place
the system in an enclosed area. Note that the iCELLis 500+ control system can supply nitrogen up to
1.5 L/min. Nitrogen supply to the iCELLis 500+ control system is the user’s responsibility.
WARNING!
Risk of injury to personnel and/or damage to equipment!
Gases supplied to the iCELLis 500+ control system must be regulated to specified pressure (maximum
2.5 barg or 36.3 PSIG) and must be oil-free, dry and clean (medical grade). To prevent possible
system component damage, do not exceed these recommendations. Each gas line should be supplied
with an ON/OFF valve and an independent regulator.
WARNING!
Risk of injury to personnel and/or damage to equipment!
User is responsible for performing assessment on the risks linked to liquids used in the iCELLis 500+
control system and bioreactor. Appropriate personal protective equipment must be used.
WARNING!
High voltage!
Always make sure this equipment is properly earthed/grounded.
WARNING!
Risk of injury to personnel and/or damage to equipment!
Only use the mains supply cord that is supplied with the iCELLis 500+ control system.
WARNING!
Risk of injury to personnel and/or damage to equipment!
When the iCELLis 500+ control system is set to manual mode, it will not be controlled by the
automation logic. Product damages or personal injuries may result!
WARNING!
Risk of injury to personnel and/or damage to equipment!
Never spray liquid or allow ingress of fluid into the fans of the iCELLis 500+ control system.
WARNING!
Risk of injury to personnel and/or damage to equipment!
Before each maintenance, cleaning or moving operation, turn the iCELLis 500+ control system OFF,
unplug the system from the AC power, shut down the gas supply, disconnect gas lines, lock the
loadcells, remove the bioreactor, remove the manifolds and all liquids.
WARNING!
Risk of injury to personnel and/or damage to equipment!
In case of leak of liquid appropriate actions must be taken for user safety according to applicable
procedures and national rules.
WARNING!
Risk of injury to personnel and/or damage to equipment!
The crated iCELLis 500+ control system should always be lifted in the upright position. The hardware
should only be lifted from a side. Before lifting, ensure that the lifting device forks pass all the way
under the box section of the hardware.
WARNING!
Risk of injury to personnel and/or damage to equipment!
The repositioning of the iCELLis 500+ control system must be done by two or more people due to the
weight of the system.
WARNING!
Risk of injury to personnel and/or damage to equipment!
Manipulation and repositioning of the bioreactor on and off the iCELLis 500+ control system docking
station must be completed when the iCELLis 500+ bioreactor is completely empty and must be done
by two people due to the weight of the bioreactor.
