Izon qNano, User Manual, Page: 27 / 56

VARIABLES TO CONTROL AT DIFFERENT
ANALYTICAL STAGES
For efficient method development for a TRPS study, breaking up the
experimental plan into three stages can be helpful.
2 /
STAGE DETAILS
Pre-analytical — Develop theoretical understanding
— Do some feasibility studies (for novel samples)
— Identify suitable protocols and consumables
— Method verification – identify controls needed
Analytical — Optimise instrument operation conditions
— Collect high-quality data
— Adjust method if needed
Post-analytical — Analyse data quality
— Identify study limitations and suggest improvements
27 www.izon.com