Freeze-dryer Epsilon 1-4 LSCplus
Freeze-dryer Epsilon 2-4 LSCplus
1 General information
Version 04/2014, Rev. 2.13 of 01/12/2021
• sb
11 / 148
Translation of the original operating manual
The chemical attack on devices and accessory components can be
significantly reduced by immediate cleaning after the end of operation. All
parts of the freeze-dryer that have come in contact with the product must
be checked regularly for damages and replaced if necessary.
The following features are not permissible or must be deactivated:
• omission or removal of product temperature sensors of the PT100 or
LyoRx type or of specially connected PT100 sensors (with a cable
connection),
• omission or removal of WTMplus,
• omission of the LyoCoN process or removal of the LyoCoN reservoir
and sealing of the access opening.
NOTE
Solvents that are not listed in the table above, or the listed solvents in a
concentration higher than 10% by volume, must not be used!
Freeze-drying of acid-containing products
Freeze-drying of products containing acids is only permissible if special
protective measures and equipment-related precautions are taken.
Otherwise, there is a risk of damage to property and personal injury.
Consultation of Martin Christ Gefriertrocknungsanlagen GmbH is absolutely
mandatory in order to define the measures that need to be taken!
Freeze-drying of azide-containing products
Freeze-drying of products containing azides is only permissible following a
case-by-case examination and the written approval by Martin Christ
Gefriertrocknungsanlagen GmbH, since azides may form explosive dust-
air-mixtures and also explosive metal azides when combined with non-
ferrous metals (e.g. copper, brass, bronze)!
Decontamination with hydrogen peroxide (H
2
O
2
)
Decontamination of the freeze-dryer with hydrogen peroxide (H
2
O
2
) in
combination with an H
2
O
2
steam generator is only permissible if the freeze-
dryer is equipped with the following:
• key switch for H
2
O
2
operation,
• removable handles,
• flange connections with specially secured locks on the chamber,
• adapted control system.