Biotage ELSD-1080, Operation Manual

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Biotage ELSD-1080
internal timer and trigger the on-board timetable a contact
closure input via the I/O connector on the rear of the detector
is required (see Section 2.5, page 25).
When the on-board timetable is triggered, the front panel of the
ELSD will display “TTRUN” above the output, as shown in Figure 8.
When the timetable is running, the current and the total run time
are displayed, in minutes, at the top-centre of the ELSD display.
When the timetable reaches the end of its run time, the ELSD
will revert to RUN mode and be primed ready to start the
timetable again.
During an active timetable, where the evaporator temperature
is being controlled, the status of the detector will change from
READY to NOT READY. This is normal behavior and will not
affect the running of the timetable.
1
2
3
1. Current runtime
2. Total runtime
3. On-board Timetable is active
Figure 8. Biotage ELSD-1080 Front Panel Display During Timetable
Operation
3.7 General Considerations
The Biotage ELSD-1080 detector should be thought of as a
detector like any other designed for liquid chromatography. The
main distinguishing feature is the ability to evaporate the
solvent from the column eluent. Therefore, normal system set-
up precautions should be remembered when starting to use the
detector. Any solvent intended for use with the ELSD-1080
detector should be fully miscible with any previously used in the
liquid chromatograph; if there is any uncertainty, then a
mutually miscible solvent should be run through the system as
an intermediate liquid. The intended eluent should be
thoroughly degassed (aqueous mobile phases), contain no non-
volatile salts or material and should be fully compatible with the
cartridge. All connections should be made with zero dead
volume fittings and tubing with an I.D.
≤ 0.010in.
Publication date: July 2010 41