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UGO BASILE - I

TALY

 

Page 7 

38500 Instruction Manual (Rev.1)

 

 

UGO BASILE DOES NOT ACCEPT ANY RESPONSIBILITY FOR 
PROBLEMS OR HARM CAUSED TO THINGS OR PERSONS ARISING 
FROM: 

  INCORRECT ELECTRICAL SUPPLY; 

 INCORRECT 

INSTALLATION PROCEDURE; 

  INCORRECT OR IMPROPER USE OR, IN ANY CASE, NOT IN 

ACCORDANCE WITH THE PURPOSE FOR WHICH THE INSTRUMENT 
HAS BEEN DESIGNED AND THE WARNINGS STATED IN THE 
INSTRUCTION MANUAL SUPPLIED WITH THE INSTRUMENT; 

  REPLACEMENT OF ORIGINAL COMPONENTS, ACCESSORIES OR 

PARTS WITH OTHERS NOT APPROVED BY THE MANUFACTURER; 

  SERVICING CARRIED OUT BY UNAUTHORIZED PERSONNEL. 

 

 

4

 

OPERATION  

The PAM device is a simple and easy-to-use device. As usual in any behavioral 
measurement, care must be taken to by the operator to guarantee a consistent performance 
of the test.   

When using the PAM, we can envisage two main potential sources of experimental 
variability: the first is the animal emotional state, which can be overcome by preliminary 
habituation procedures and the second is the rate at which the operator applies the force.  
The PAM device incorporates several tools to help the operator consistently apply the 
desired amount and rate of force on the animal.  These tools are described in the following 
paragraphs.  

 

4.1

 

First time operation 

After charging PAM for at least 1 hour, plug in the large transducer and turn the instrument 

ON

 by pressing the 

ON/OFF

 button.  Once the introduction is completed, the initial menu 

will appear as below. 

 

 

 
 

The lower line of the display indicates the current functions of the three 

soft buttons

 

labelled F1, F2 and F3.  In this case, F1 is 

Measure

, F2 is not being used and F3 is 

Configure

.   

 

Main Menu 

-------------------- 
 
Measure    Configure 

Содержание PAM

Страница 1: ...P A M PRESSURE APPLICATION MEASUREMENT Cat No 3 8 5 0 0...

Страница 2: ......

Страница 3: ...WARNINGS WHICH MUST BE FOLLOWED TO ENSURE SAFE OPERATION AND TO RETAIN THE INSTRUMENT IN SAFE CONDITIONS SERVICE AND ADJUSTMENTS SHOULD BE CARRIED OUT BY QUALIFIED PERSONNEL AUTHORIZED BY UGO BASILE...

Страница 4: ...r measuring mechanical pain threshold in experimental joint hypersensitivity models in rodents The PAM device has been designed and validated specifically for the mechanical stimulation and assessment...

Страница 5: ...R small TRASDUTTORE small 38500 1 SOFTWARE SOFTWARE 38500 323 1 EXTERNAL TRIGGER SWITCH TRIGGER ESTERNO 52010 325 1 USB LEAD CAVO USB OPTIONAL 38500 006 0 PAW TRANSDUCER TRASDUTTORE DA ZAMPA DATE Seri...

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Страница 7: ...T TIME OPERATION 7 4 2 ROUTINE OPERATION OF THE INSTRUMENT 10 4 2 1 TURNING THE INSTRUMENT ON 10 4 2 2 AUTOMATIC DIMMING OF THE DISPLAY 10 4 2 3 MENU OPERATION 10 4 2 4 TURNING THE INSTRUMENT OFF 11 4...

Страница 8: ...NLOADED DATA 24 6 5 EXCEL FILES 26 7 MAINTENANCE 26 7 1 LONG INACTIVITY 26 7 2 CUSTOMER SUPPORT 27 8 ORDERING INFORMATION 27 9 BIBLIOGRAPHY 28 9 1 METHOD PAPER 28 9 2 OTHER PAPERS MENTIONING UB PAM 28...

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Страница 10: ...UGO BASILE ITALY Page iv CONTENTS...

Страница 11: ...transducer is mounted on the operator s thumb so that routine procedures may be employed to examine and test the joint concerned The completion of each test may be indicated by the operator either by...

Страница 12: ...ce applicator is also available to measure pain threshold in paws and muscles see also paragraph 2 3 Figure 2 Paw Transducer 2 INSTRUMENT DESCRIPTION The 38500 is composed of 1 Handheld Electronic Uni...

Страница 13: ...ree buttons below the display as soft buttons whose functions change at different stages of the PAM program The lower line of PAM s 4 by 20 character display is normally used to indicate the current f...

Страница 14: ...y including muscles and paws or for other joints such as the ankle Each transducer contains a memory chip which identifies the type of transducer and its specific characteristics including all relevan...

Страница 15: ...ing list to hand and visually inspect the instrument as soon you take it out of the packaging Use the Check List supplied If the instrument is damaged or after having tested it fails to meet rated per...

Страница 16: ...the PAM Software The software provided with PAM should be installed on a suitable Windows PC running Windows Vista or XP First install the software by double clicking on the Set up exe file follow the...

Страница 17: ...rantee a consistent performance of the test When using the PAM we can envisage two main potential sources of experimental variability the first is the animal emotional state which can be overcome by p...

Страница 18: ...and then displays Apply gentle1 force to the transducer The display changes to typically For as long as the force is applied steadily the Force value will indicate the applied force in gf and the Time...

Страница 19: ...each measurement Date Time Progressive number of the measurement Automatic or Foot Pedal measurement mode Peak Force Peak Time are shown and the measurements can be browsed by simply pressing Next Pr...

Страница 20: ...4 2 2 Automatic dimming of the display The display backlight may be configured to dim automatically in most menus if no soft button is pressed during a preset period which may be set between 2s and 29...

Страница 21: ...ault setting is never PAM will also switch itself OFF automatically if the battery voltage falls below a critical level 4 3 Main Menu The Main Menu is the first menu which appears when PAM is switched...

Страница 22: ...ically by releasing the pressure on the transducer at the end of the test Auto Measurement 2 The transducer is the Large transducer with a full scale force measurement of 1500gf The warning sound abov...

Страница 23: ...dicates the total length of the measurement The user must choose whether to Reject or Accept the results of the test If the result is rejected the user is given the option to finish making measurement...

Страница 24: ...on the assumption that future measurements will be similar in length to those already stored The number of tests that can be stored strongly depends on the duration of each test Press Return to return...

Страница 25: ...PAM These include options related to the measurement process such as whether the measurement is ended automatically by removing the applied force or manually by pressing the foot trigger switch but al...

Страница 26: ...rm or only the peak value store waveform Ask whether the test is on Left or Right Do not Use Subject Numbers Do not only use Test number Use the applied force rate meter during tests Do not only use T...

Страница 27: ...will be retained but PAM may not be used until it is connected to an active PC or a USB power adapter using the USB lead provided Clearly it is not advisable to allow the battery to drop to this criti...

Страница 28: ...ustment ranges and default values Configuration flags which may be set or cleared Whether each measurement is ended automatically on the force level default or by pressing the foot pedal Whether every...

Страница 29: ...om 1s to 29s in steps of 1s or never with a default value of never The target force rate which is the ideal rate at which the stimulus force should be applied The date and time settings of PAM s inter...

Страница 30: ...ncludes changing the slope of the PAM target rate which is in fact from control unit see paragraph 4 5 Connect the PAM device to the PC using the supplied USB cord then run the Ugo Basile PAM Software...

Страница 31: ...ft side is a visual guide during the experiments The operator should practice trying to match the applied force yellow line with this blue line of the display As you can see the yellow is the actual f...

Страница 32: ...nge the slope on the visual display graphic side of the software one must return to the PAM controller toggle through the selected menus to reach the proper instructions When the rate of application o...

Страница 33: ...ry make some new measurements and Accept them Next one the PAM controller select Transfer Data to PC from the PAM Measure menu of the PAM device The traffic lights on the PAM Software will show green...

Страница 34: ...009 will be found in the folder C PAM Data 090723 Individual files containing the downloaded data are named automatically according to the date as above followed by two letters which progress from AA...

Страница 35: ...s until the software shows the required test If the left or the right mouse button is clicked in the display area of the graph the vertical white cursor line is displayed and the force and time relati...

Страница 36: ...me as the corresponding PAM data file and is stored in the same folder The data in the Excel file consists of columns for measurement number peak force and peak position filled with the values for eac...

Страница 37: ...t to our factory for repair we recommend you to contact our service department to obtain a return authorization number R A N and shipping packing instructions We may not be held responsible for damage...

Страница 38: ...or Detection of Primary Mechanical Hyperalgesia in Rat and Mouse Antigen Induced Knee Joint Arthritis Methods Findings in Exp Clinical Pharmacol 32 8 581 589 2010 T Schwagarus et al A New Method for M...

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