3
Routine Maintenance
Preventive Maintenance
24
Accela RI Detector Hardware Manual
Thermo Scientific
Preventive Maintenance
In addition to standard laboratory cleanliness practices, Thermo Fisher Scientific recommends
the following preventive measures:
• Use only high-purity liquid in all “wetted surface” contact areas for the analysis, for
flushing, and for cleaning. Use only high-purity gases when drying the same areas.
• Thoroughly flush all plumbing (including the flowcell) after each use. Remember that
water is the recommended “last contact” liquid.
Keeping the flowcell absolutely clean is necessary to maintain low-noise operation.
Organic films and residues are major causes of noise. Also consider the analytical
solutions passing through the flowcell. If they pose a possible contamination problem,
flush the flowcell with water or methanol. If this does not remove the contamination,
clean the flowcell with a dilute solution of nitric acid, followed by a water rinse.
• Thoroughly flush and clean all peripheral plumbing, pumps, and so on before connecting
them to the flowcell.
• To avoid particulate contamination and fluid path blockage, maximize the use of
filtration.
• Avoid leaving buffers standing in the flowcell for long periods. Plan your use to minimize
standing time between runs.
Table 4.
Recommended routine maintenance
Procedure
Interval
Cleaning external surfaces
“Cleaning the External Surfaces
Cleaning the flowcell
As needed
*
(See
*
Good Laboratory Practices dictate flushing the flowcell with clean solvent after every use. This will greatly reduce
the frequency with which you need to clean it.
Flushing flowcell
As needed, to replace or refresh the solvent (See
.)
Lamp replacement (performed by a
Thermo Fisher Scientific field service
engineer)
Every 4.5 years or as needed
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