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Due to a high speed grinding process a warming of the formulation up to 50°C (122°F)
may occur. Since this warming may not be suitable for some of the substances (e.g.
metronidazole), we recommend continiously checking the temperature.
In order to gently work the substances, making use of these programs, the rpm and lifting
speed can be individually selected and adjusted.
The relatively large surface of the UNGUATOR® SMB benefits the formation of an agglomerate
grinding process. This can be quickly homogenized with the rest of the base even when using
larger UNGUATOR® Jar sizes. After finalizing the pregrinding process both the remaining
base and all substances will be weighed in.
4.4.5 Suspension >2%
(Mixing semisolid substances with a portion of microfine, agglomerated, optionally
finegrained solid substances of more than 2 %).
Examples: Zincum oxydatum, acidum salicylicum
We recommend using the UNGUATOR® SMB.
For suspensions with ingredient content above 2% pregrinding is not required. For
preparation please add 50% of the required base in the UNGUATOR® jar first and then
include the micronized solid parts. Add the remainder of the base on top of the ingredients
in order to avoid remaining powder sticking to the blades.
4.4.6 Gel
(Mixing of gel).
Example: Hydroxypropyl cellulose 400
We recommend using the UNGUATOR® Disp. Blade for up to 200 ml.
Basic gel approaches are mixed, with several intervals, at high speed during the required swell
time thus preventing agglomerations and slightly reducing soaking time. Principlerelated,
trapped air will normally clear after the preparation would settle for a while.
