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Endress+Hauser Analytik Jena Biometra TAdvanced 384 Скачать руководство пользователя страница 17

Biometra TAdvanced

Function and setup

Version 02_20

17

3.3

Display

The Biometra TAdvanced thermal cycler features a 7" state-of-the-art color
touchscreen user interface. The touchscreen is built-in at a flat angle to ensure
reflection-free viewing and ergonomic programming. For programming PCR protocols
the software incorporates Biometra's proven spreadsheet philosophy and alternatively
offers graphical programming. One touch of a button leads from the spreadsheet to
the alternative graphical programming mode. This makes the creation of new
programs or editing existing programs fast and easy.

3.4

User-specific quick start of programs

Many other thermal cyclers offer a so-called "List of latest programs used". In the list of
latest programs used a certain number of PCR programs is collected and offered for
quick start. The list is typically ordered only by date and the user has to search for the
desired program. In contrast the Biometra TAdvanced software creates a user-specific
list and only the latest programs started by the currently logged-in user are offered for
quick start. Even if a lab member does not use the device for a longer time, the
information on the latest programs started by this user will not get lost.

For maximum convenience the Biometra TAdvanced software additionally features a
program preview. Before the start of a program the protocol steps are summarized in a
clearly arranged table by the program preview tool. The preview therefore provides a
comprehensive overview of the protocol structure without the need to access
programming screens. The program preview is also available before the quick start of
programs.

3.5

Easy programming

Creating new PCR programs takes a lot of time if for each single step all parameters
have to be set manually. The Biometra TAdvanced offers two options for easy protocol
creation:



Pre-installed program templates



Protocol wizard

The Biometra TAdvanced software offers several pre-installed program templates for
different applications. The program templates provide a general protocol structure and
can be easily adapted for the current experiment.

The protocol wizard offers the comfort to create specific PCR programs by just a few
inputs. The protocol wizard is based on program templates for specific polymerases.
For up to eight different polymerases program templates can be saved in the Biometra
TAdvanced software and just the annealing temperature, cycle number and product
length has to be filled in to create a specific PCR program. Optionally two-step or
three-step PCR programs can be created by the software. Furthermore the protocol
wizard includes a primer annealing temperature calculator and the calculated
annealing temperature T

a

value can be used for protocol creation.

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Содержание Analytik Jena Biometra TAdvanced 384

Страница 1: ...Operating Manual Biometra TAdvanced High performance thermal cycler for DNA amplification by PCR...

Страница 2: ...Service analytik jena com http www analytik jena com Operating manual valid from software version ME 1 70 RE 1 46 Microsoft and Windows are registered trademarks of Microsoft Corp The identification w...

Страница 3: ...h speed thermoblock 16 3 2 High Performance Smart Lid 16 3 3 Display 17 3 4 User specific quick start of programs 17 3 5 Easy programming 17 3 6 Linear Gradient Tool 18 3 7 GLP compliance 18 3 8 Open...

Страница 4: ...9 3 Continuing the program 75 9 4 Skipping a step 75 9 5 Stopping the program 75 10 Protocol Wizard 77 10 1 Select Polymerase 77 10 2 Enter a new polymerase or edit a polymerase 78 10 3 Delete a poly...

Страница 5: ...2 Voltage selector switch on the underside of the device 20 Fig 3 Front view of the Biometra TAdvanced 22 Fig 4 Rear view of the Biometra TAdvanced 23 Fig 5 Quick block exchange 24 Fig 6 Placement of...

Страница 6: ...9 Fig 51 Spreadsheet view 70 Fig 52 Display during the run in a graphical spreadsheet and gradient view 70 Fig 53 Graphical view 71 Fig 54 Spreadsheet view 71 Fig 55 Display during the run in a graphi...

Страница 7: ...91 Program view screen 102 Fig 92 Power on log file screen 103 Fig 93 Extended self test log file screen 103 Fig 94 Error log file screen 104 Fig 95 Sample block loaded with plasticware for the exten...

Страница 8: ...Contents Biometra TAdvanced Manual 8 Version 02_20...

Страница 9: ...mes the terms protocol and program are used synonymously these are one or more programmed temperature steps with different or the same holding times and cycles Instructions for actions which occur in...

Страница 10: ...cycler is suitable for fast PCR applications thereby helping to shorten program run times 1 3 Warranty and liability The warranty duration and liability comply with the legal requirements and the prov...

Страница 11: ...afety symbols Replace damaged safety symbols immediately The following safety symbols are attached to the inside of the heated lid and the rear of the device CAUTION Hazard area Proceed with due care...

Страница 12: ...ons of the respective country of operation must be observed and adhered to The operator must ascertain the latest version of these regulations The operating manual must be accessible to the operating...

Страница 13: ...into the thermal block no shaking and whose lids seal tightly 2 6 2 Safety instructions protection against explosion and fire The Biometra TAdvanced must not be operated in an explosive environment T...

Страница 14: ...ed an empty tube of the same height must additionally be placed at each corner position of the block If the number of samples in the block is too low there is a risk of the tubes being damaged and sam...

Страница 15: ...metra TAdvanced 384 with aluminum block Biometra TAdvanced 384 G with aluminum block with gradient function Biometra TAdvanced Twin 48 with aluminum twinblock Biometra TAdvanced Twin 48 G with aluminu...

Страница 16: ...luable silver blocks against corrosion the block surfaces are gold plated A rubber seal on the heated lid forms an encapsulated space around the sample block as soon as the lid is closed The closed sp...

Страница 17: ...software additionally features a program preview Before the start of a program the protocol steps are summarized in a clearly arranged table by the program preview tool The preview therefore provides...

Страница 18: ...n extended self test that can be initiated by the user The results of the extended self test are summarized in a protocol and stored by the device In addition to the self test functions the device cre...

Страница 19: ...x 070 202 Biometra TAdvanced Twin 30 Aluminum 846 x 070 213 Biometra TAdvanced Twin combi Aluminum 846 x 070 215 G gradient S silver block X 2 for 230 V EN DE 4 for 115 V EN 5 for 100 V EN DE Base un...

Страница 20: ...etra GmbH Do not attempt to operate the device if there is any visible damage Keep the original packaging for possible return The Biometra TAdvanced must always be transported in its original packagin...

Страница 21: ...t a minimum distance of 10 cm between the rear of the device and the wall or other objects In case of several cyclers side by side running simultaneously we would recommend to keep a distance of at le...

Страница 22: ...Biometra TAdvanced 22 Version 02_20 5 Control elements 5 1 Biometra TAdvanced front view Fig 3 Front view of the Biometra TAdvanced 1 Dial for adjusting the contact pressure 2 Lid closing button 3 Di...

Страница 23: ...for quick block exchange is available for all model types To change the block 1 Switch off the device 2 Lift release lever on the backside 1 in Fig 5 then pull block slowly to the back 2 3 Insert the...

Страница 24: ...nt click into position 2 Turn the lid wheel clockwise until the clutch mechanism is activated you will hear a clicking noise NOTICE The strength of the lid contact pressure has been designed for a ful...

Страница 25: ...pressure Always follow the sequence below when opening the lid If the lid is opened under pressure the locking mechanism may be damaged Reduce the contact pressure of the lid completely by turning th...

Страница 26: ...ords have to be defined For this purpose the Biometra TAdvanced software offers a keyboard to enter characters digits and special characters Fig 7 Keyboard The keyboard offers the following special ke...

Страница 27: ...INGLE CHARACTER DELETE ALL CHARACTERS TAB INFINITE 5 5 3 Cursor keys The Biometra TAdvanced software uses lists tables or graphical representations Whenever the number of entries becomes higher than t...

Страница 28: ...and icons used The Biometra TAdvanced software uses the following icons Command Icon HOME NEXT BACK RIGHT LEFT UP DOWN CONFIRM CANCEL LOGIN USER MANAGEMENT USER MANAGEMENT ON OFF NEW USER DELETE USER...

Страница 29: ...CENTRATION EDIT PRIMER CALCULATE PRIMER SAVE ANNEALING TEMPERATURE TA PROTOCOL WIZARD INFO INCUBATION START INCUBATION PROGRAMS NEW PROGRAM NEW FROM TEMPLATE OPEN TEMPLATE COPY PROGRAM COPY ALL PROGRA...

Страница 30: ...PAUSE PROGRAM START PROGRAM CONTINUE PROGRAM SKIP STEP CHOOSE BLOCK START PROGRAM BLOCK STOP GRAPHICAL VIEW SPREADSHEET VIEW GRADIENT DISPLAY EDIT STEP INSERT STEP DELETE STEP TEMPERATURE INCREMENT T...

Страница 31: ...TING ON TOOLS SETTINGS DATE AND TIME AUTOMATIC USER LOGOUT BEEPER NETWORK DISPLAY BRIGHTNESS DISPLAY DARKER DISPLAY BRIGHTER TOUCHSCREEN CALIBRATION FACTORY SETTINGS DOCUMENTATION RUN LOG FILE RUN LOG...

Страница 32: ...n VIEW PROGRAM POWER ON LOG FILE SELF TEST LOG FILE ERROR LOG FILE EXTENDED SELF TEST START EXTENDED SELF TEST STOP EXTENDED SELF TEST SERVICE INFO FILE BACKUP SAVE BACKUP FILE LOAD BACKUP FILE DELETE...

Страница 33: ...e Biometra TAdvanced has performed the power on self test the login screen is displayed The login screen offers the following functions Command Function Section LOGIN Starts the login dialog See secti...

Страница 34: ...most recently logged in user is always shown in the first position at the top left of the screen All the other buttons become arranged from top left to bottom right according to the date and time of...

Страница 35: ...2_20 35 Fig 12 Enter password screen 6 4 Home screen After user login the Biometra TAdvanced software shows the home screen The home screen offers the following functions Biometra TAdvanced Mono Biome...

Страница 36: ...block status can be FREE RUNNING or PAUSE and is indicated by the color of the button and the textbox in the middle of the button 2 in Fig 14 In the line above the textbox the current block temperatu...

Страница 37: ...see section Home screen p 35 Note The quick start function can only be activated if the current block status is FREE see section Quick start function p 37 If the status is RUNNING or PAUSE a touch of...

Страница 38: ...ers with the right WRITE DELETE OWN PROGRAMS activated see section Editing user settings p 96 ENABLE A USER TO EDIT OR DELETE OWN PROGRAMS Press the corresponding button to activate the programming mo...

Страница 39: ...ome screen after user login the software will show a user specific list of the latest programs used for quick start LOGIN SCREEN List containing the latest programs used HOME SCREEN User specific list...

Страница 40: ...ode or select a program from the list of templates EDIT NEW FROM TEMPLATE 6 7 Incubation mode Note Programs can only be started by users with the right START STOP PROGRAMS activated see section Editin...

Страница 41: ...nds can be used STOP PAUSE CONTINUE SKIP Note To stop the incubation use the corresponding command Do not switch off the device while the incubation is running The device will react like after a power...

Страница 42: ...ck temperature and hold time using the keypad Set whether the heated lid should be on or off and whether it should preheat or not using the corresponding buttons see Fig 18 INCUBATE Note To set the ti...

Страница 43: ...ncubation the following commands can be used STOP BLOCK STOP PAUSE CONTINUE SKIP Note To stop the incubation use the corresponding command Do not switch off the device while the incubation is running...

Страница 44: ...1 Programming modes The Biometra TAdvanced software offers spreadsheet or graphical programming Use the buttons to toggle between the two modes The following screenshots show the spreadsheet and graph...

Страница 45: ...ion Editing steps p 49 Go to See section Editing steps p 49 Cycles See section Editing steps p 49 Temperature increment T C See section Editing steps p 49 Time increment t s See section Editing steps...

Страница 46: ...NEW FROM TEMPLATE 4 The program template screen opens see Fig 26 Search for a program template using the cursor keys and press the corresponding button to select it UP DOWN Note The Biometra TAdvance...

Страница 47: ...template has a specific name which is superimposed in the programming screen To enter a name touch the NAME input field and enter a new name using the Biometra TAdvanced keyboard see section Keyboard...

Страница 48: ...unnecessary cooling against the heating cover is required 7 5 Preheating the heated lid The heated lid can be set to preheating ON or OFF using the corresponding buttons PREHEAT HEATED LID OFF PREHEAT...

Страница 49: ...ng rate can be set from 0 1 C s to max in tenths of a degree The maximum ramp rate is sample bock specific The ramp rate specifies the speed at which the selected step is reached with It is possible t...

Страница 50: ...rm the settings for each single parameter or step and to leave the screen for editing program steps Instead you can fill in the parameters for all steps subsequently and confirm your entries after all...

Страница 51: ...ng input field TEMPERATURE INCREMENT T Note Programmed temperature increments only become active if they are in loops If a temperature increment has been programmed the small symbol will be shown at t...

Страница 52: ...ed If the ramp rate has been adjusted the small symbol will be shown at the corresponding step in the graphical programming mode For Biometra TAdvanced monoblock models Note To be able to use the grad...

Страница 53: ...for a specific column in the sample block For example the annealing temperature in a 96 well sample block corresponds to the temperature in column 6 The column number is indicated in parenthesis next...

Страница 54: ...adient is established across the sample block in the annealing step so that there are different temperatures from column to column Fig 33 Temperature gradient on a 48 well sample block In a specific c...

Страница 55: ...or a specific column in the sample block For example the annealing temperature in a 48 well Twinblock corresponds to the temperature in column 4 The column number is indicated in parenthesis next to t...

Страница 56: ...If you attempt to start a gradient program on a block without gradient function the following message appears Fig 36 Temperature gradient query 7 6 2 Direct programming of program parameters for a ste...

Страница 57: ...ate R C s To edit program parameters in the graphical view press the corresponding input field for the parameter that you want to edit for the step see Fig 38 Program options loops temperature and tim...

Страница 58: ...ter option button Temperature increment option button Time increment option button Ramp rate option button Input field for program option loop counter here When you press a cell in the spreadsheet vie...

Страница 59: ...l program parameter editing If the sample block is gradient enabled you also have the option of programming a gradient step To do this when editing the temperature press the GRAD button GRADIENT A gra...

Страница 60: ...f cycles remains the same 7 8 Deleting a step To delete a step select a program step on the Biometra TAdvanced spreadsheet or graphical programming screen and press the DELETE button DELETE Note If a...

Страница 61: ...rograms will increase by 1 and the new program is saved at the selected location Fig 41 Program overview screen There is also the option of selecting a user directory or a program location using the q...

Страница 62: ...program name To do this press the SAVE AS button and enter the new program name using the Biometra TAdvanced keyboard see section Assigning program names p 47 SAVE AS After selecting the user directo...

Страница 63: ...rt programs of others even if the right START STOP PROGRAMS is activated ENABLE A USER TO START OR STOP PROGRAMS ENABLE A USER TO READ ALL PROGRAMS OF OTHER USERS The Biometra TAdvanced software offer...

Страница 64: ...ion of selecting a user directory or a program location using the quick select function For the selected program a preview opens with general information on the program and the steps listed in a table...

Страница 65: ...isplayed in the list the buttons above and below the lists can be used to scroll up and down To copy the selected program press the COPY button COPY Touch the corresponding buttons to select a user di...

Страница 66: ...onding button to select a user directory on the Biometra TAdvanced program overview screen see Fig 43 p 63 If the number of user directories or programs is higher than the maximum number that can be d...

Страница 67: ...AMS activated see section Editing user settings p 96 ENABLE A USER TO DELETE OWN PROGRAMS ENABLE A USER TO COPY AND SAVE ALL PROGRAMS OF OTHER USERS To delete a program touch the corresponding buttons...

Страница 68: ...right WRITE DELETE ALL PROGRAMS activated see section Editing user settings p 96 ENABLE A USER TO DELETE OWN PROGRAMS ENABLE A USER TO COPY AND SAVE ALL PROGRAMS OF OTHER USERS To delete all programs...

Страница 69: ...1 SAMPLE BLOCK 2 9 1 Display during a run After a program has been started see section Starting a program p 63 the Biometra TAdvanced software can display the currently running program in a spreadshee...

Страница 70: ...Running pausing continuing and stopping programs Biometra TAdvanced 70 Version 02_20 Fig 51 Spreadsheet view Fig 52 Display during the run in a graphical spreadsheet and gradient view...

Страница 71: ...Biometra TAdvanced Running pausing continuing and stopping programs Version 02_20 71 Fig 53 Graphical view Fig 54 Spreadsheet view Biometra TAdvanced Twin...

Страница 72: ...d has reached the target temperature and the 40s equilibration phase has passed the first program step starts During the program run the current step is highlighted in yellow in the graphical and spre...

Страница 73: ...ogram To pause a program press the PAUSE button on the Biometra TAdvanced run display screen see Fig 52 p 44 PAUSE The word Pause is shown and the pause time is counted in the REMAIN TIME field Fig 56...

Страница 74: ...be programmed see section Editing steps p 49 then the pause step is automatically started by the device Note If the device is switched off during a pause step this will be recognized as a power failu...

Страница 75: ...kip a program step press the SKIP button on the Biometra TAdvanced run display screen see Fig 52 p 70 SKIP The Biometra TAdvanced will continue with the next program step and skip the current step 9 5...

Страница 76: ...ced offers the option to stop only one block or to stop both blocks simultaneously Therefore press the following button BLOCK STOP Activate the corresponding checkboxes to select the sample blocks to...

Страница 77: ...e The protocol wizard uses polymerase specific program templates to create PCR programs Program templates for up to 8 polymerases can be stored by the TAdvanced software Fig 63 Select polymerase scree...

Страница 78: ...value and has to be set individually for each primer pair see section Primer Annealing Temperature Calculator p 82 The hold time for the elongation step becomes calculated by the expected product len...

Страница 79: ...ymerase list is pre selected However the storage place can be modified by using the cursor key function above and below the list To save the new or edited polymerase press the SAVE button SAVE Note If...

Страница 80: ...m the primer annealing temperature Ta see below is used for the annealing and extension step 2 Enter the PCR product length Note The product length is used by the software to calculate the elongation...

Страница 81: ...ng all program parameters press the NEXT button NEXT The next screen lists the all steps of the program that will be created by the software Fig 68 Protocol wizard view parameter screen Press the CREA...

Страница 82: ...nnealing Temperature Calculator Based on the primer sequences the Biometra TAdvanced protocol wizard can calculate the theoretical primer annealing temperature Ta Press the CALC TA button in the TAdva...

Страница 83: ...imer concentration salt concentration and magnesium concentration can be adjusted Touch the corresponding input field and enter values using the keypad The concentrations have the following default va...

Страница 84: ...mer annealing temperature Ta based on the primer Tm values as follows 1 For each primer the melting temperature is calculated using the following equation according to Wallace et al 1 Tm w A x T 2 y G...

Страница 85: ...les SINF See section Service info file SINF p 107 BACKUP Saves all folders programs users and user rights to USB See section Backup p 108 CYCLER INFO General information on the device See section Cycl...

Страница 86: ...tic user logout p 88 BEEPER Switches the beeper on or off See section Configuring the beeper p 89 NETWORK Defines network settings See section Network p 89 DISPLAY BRIGHTNESS Adjusts the display brigh...

Страница 87: ...RS MINUTES SECONDS Fig 74 Date and time entry screen Activate the corresponding input field and use the keypad on the right side of the date and time entry screen to enter digits The following buttons...

Страница 88: ...n automatic user logout function The automatic user logout can be switched ON or OFF by using the corresponding button AUTOMATIC LOGOUT ON AUTOMATIC LOGOUT OFF If automatic user logout is switched on...

Страница 89: ...ivating the corresponding checkbox Fig 76 Beeper configuration screen 11 1 4 Network The NETWORK menu item can be used to configure basic settings or show a list of network users Press the correspondi...

Страница 90: ...ight side of the screen The port number can entered manually in both setting types static and DHCP The following buttons may be helpful when completing the fields DELETE SINGLE CHARACTER DELETE ALL CH...

Страница 91: ...thermal cycler Notification system for monitoring status changes on selected blocks of a thermal cycler Store PCR protocols on the terminal This can be stored on a PC using a USB stick Copy PCR proto...

Страница 92: ...see section Editing user settings p 96 ENABLE A USER TO CONFIGURE THE SYSTEM CONFIGURATION To calibrate the screen follow the instructions and touch the screen at the center of the displayed circle T...

Страница 93: ...observe the following guidelines 1 The factory setting for the administrator password is ADMIN Please change the password after switching on user management to protect the system from unwanted modifi...

Страница 94: ...iometra TAdvanced user management Fig 83 Configure user management screen If the user management is switched off all new users have all rights and can access all software functions With the user manag...

Страница 95: ...deleted by all users Available users are listed on the Biometra TAdvanced user management screen see Fig 82 sorted by the date and time of the last login and the username the initials and the group a...

Страница 96: ...ion is optional However if no password is used your account containing all of your programs might be modified or deleted by unauthorized persons Note The language setting is user specific For each use...

Страница 97: ...rt and to create a backup of the system Folders programs users and rights settings can be restored from a backup file To modify the user rights press the USER PROPERTIES button USER PROPERTIES In the...

Страница 98: ...ITE DELETE PROGRAMS OF OTHER USERS Allows to edit copy and delete all programs of all users READ ALL PROGRAMS OF OTHER USERS If inactive the access is limited to own programs Programs of others cannot...

Страница 99: ...r of the Biometra TAdvanced Confirm the confirmation prompt to delete the user Fig 87 Confirmation prompt After confirmation the user and all of his programs will be deleted 11 3 Documentation The Bio...

Страница 100: ...erview screen The run log files are sorted by date and time The run log file for the program that was last started is shown at the first position in the table The initials of the user who started the...

Страница 101: ...ber of the Biometra TAdvanced thermal cycler Start and end time of the program run Sample block type Date of the program run Block serial number Name of the vendor Block number Software version Messag...

Страница 102: ...ALL RUN LOG FILES ON USB button To export a specific run log file select a log file from the list on the run log file overview screen see Fig 89 p 100 and press the SAVE RUN LOG FILE ON USB button SA...

Страница 103: ...est the Biometra TAdvanced checks several functions and components like cooler thermal tracking heating and cooling rate refrigeration gradient heated lid and regulation see section Extended self test...

Страница 104: ...ding on the voltage type of the device 100 V 115 V 230 V 10 each The device must be cooled to the ambient temperature of 20 C to 25 C after the last application During the extended self test the Biome...

Страница 105: ...microplate or if applicable two strips or a row of tubes in the first and last row into the sample block see Fig 95 It is very important to load the sample block as described with plasticware because...

Страница 106: ...s shown and all other tests for which no result is shown are not finished yet Note The extended self test will take approx 30 minutes The device is blocked while the test is running and no other progr...

Страница 107: ...he device and can be viewed by the user see section Extended self test log file p 103 11 5 Service info file SINF The service info file is a helpful tool for remote fault diagnosis by the Biometra ser...

Страница 108: ...he backup all folders programs users and user settings can be stored to USB and transferred to another Biometra thermal cycler of the same type Fig 100 Backup file screen Connect a USB stick to the de...

Страница 109: ...ion power board Serial number cycler Software version power board logic Block type Revision number processor board Block serial number Software version processor board Software version Revision number...

Страница 110: ...Tools Biometra TAdvanced 110 Version 02_20 11 8 Contact Shows contact details for the Biometra service department Fig 102 Service department contact details screen...

Страница 111: ...below the minimum permitted temperature The lower temperature is increased to the minimum permitted value If for example a gradient is programmed from 5 C to 25 C the gradient is changed to 20 C to 2...

Страница 112: ...eral oil Ensure that the ventilation slits are clear Insufficient ventilation may cause the device to overheat Tip Clean the air inlets on the underside of the device at regular intervals to ensure op...

Страница 113: ...following buttons to toggle between the different programming modes Quick selection Graphical mode Spreadsheet mode Gradient mode Spreadsheet programming screen Graphical programming screen Enter a pr...

Страница 114: ...LY HEATING COOLING RATE TO ALL STEPS checkbox To program a gradient press GRAD On the next screen you can choose between standard STD and linear gradient programming LIN For standard programming enter...

Страница 115: ...ingle program select a directory and a program and press DELETE Confirm the confirmation prompt The Biometra TAdvanced stores the latest 5 started or edited programs for each user To quick start a pro...

Страница 116: ...er failure occurs during a run the device will continue the run at the same point when the power returns In case of long term power failure longer than 30 minutes the device keeps the sample block at...

Страница 117: ...the top of the lid wheel with a pen This overrides the clutch mechanism Take care not to apply excessive pressure Lid blocked in the top position 1 Press down the metal pin 2 Carefully turn the lid w...

Страница 118: ...compared to 0 2 ml vessels the lid temperature can have a significant impact on the effective incubation temperature For reaction volumes less than 10 l the lid temperature is recommended to be set at...

Страница 119: ...Prior to commencing any maintenance or cleaning work switch off the device and pull out the mains plug After cleaning wait until the Biometra TAdvanced is completely dry before recommissioning it WARN...

Страница 120: ...h care Wipe spilled samples or reagents immediately with an absorbent cloth or piece of paper If the Biometra TAdvanced is used for the analysis of infectious material great care must be taken because...

Страница 121: ...Please clean all device components from biologically hazardous chemical or radioactive contamination see also section Disinfecting the device p 120 Download the decontamination declaration as an edita...

Страница 122: ...tra uses an extra designed packaging system with inserts of foamed material NOTICE The thermal cycler is only protected from transport damage if the original packaging is used and the packing instruct...

Страница 123: ...t dispose of any waste materials that occur during measurements sample materials in accordance with statutory and local regulations At the end of its service life the Biometra TAdvanced and all its el...

Страница 124: ...ell strips Block material Aluminum Block coating Special alloy Block exchange optional Quick X change Block exchange time less than 10 sec Max heating rate 6 0 C sec Max cooling rate 4 0 C sec Avg hea...

Страница 125: ...Block exchange time less than 10 sec Max heating rate 8 0 C sec Max cooling rate 5 5 C sec Avg heating rate 7 0 C sec Avg cooling rate 4 5 C sec Gradient 40 C Gradient temperature range1 4 C to 99 C...

Страница 126: ...nge time less than 10 sec Max heating rate 6 0 C sec Max cooling rate 4 0 C sec Avg heating rate 5 5 C sec Avg cooling rate 3 5 C sec Gradient 30 C Gradient temperature range1 20 C to 99 C Temperature...

Страница 127: ...time less than 10 sec Max heating rate 4 0 C sec Max cooling rate 2 0 C sec Avg heating rate 3 8 C sec Avg cooling rate 1 7 C sec Gradient 24 C Gradient temperature range1 20 C to 99 C Temperature un...

Страница 128: ...optional Quick X change Block exchange time less than 10 sec Max heating rate 5 2 C sec Max cooling rate 4 1 C sec Avg heating rate 5 1 C sec Avg cooling rate 4 0 C sec Gradient 20 C Gradient temperat...

Страница 129: ...Block exchange time less than 10 sec Max heating rate 4 2 C sec 3 1 C sec Max cooling rate 3 3 C sec 2 3 C sec Avg heating rate 4 1 C sec 3 0 C sec Avg cooling rate 3 1 C sec 2 2 C sec Gradient Gradi...

Страница 130: ...otocol Wizard Program memory Total capacity of 350 programs 6 steps in up to 90 user directories Language English German Chinese Display 7 color touchscreen Automatic restart after power failure Yes H...

Страница 131: ...Biometra TAdvanced Declaration of conformity Version 02_20 131 19 Declaration of conformity...

Страница 132: ...y all 66 Cycles 50 Delete 67 Delete all 68 Editing steps 49 Gradient 52 Graphical programming 44 Heated lid temperature 47 Loop 50 Name 47 New 45 Pause 73 Preheating 48 Ramp rate 52 Save 60 Spreadshee...

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