ThermoFisher Scientific CryoMed TSCM17EA Operating And Maintenance Instructions Manual Download Page 21

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Controlled-Rate Freezer

Start Up | 15

Figure 24. Add User Screen

This screen indicates your initial setup is complete. Press the

Finish

button to complete initial setup or the Back button to

make changes.

Figure 25. Complete Setup Screen

Summary of Contents for CryoMed TSCM17EA

Page 1: ...Thermo ScientificTM CryoMedTM Controlled Rate Freezer Operating and Maintenance Instructions 331486H01 Revision A 10 22 2020 ...

Page 2: ...er Scientific makes no representations or warranties with respect to this manual In no event shall Thermo be held liable for any damages direct or incidental arising from or related to the use of this manual 2020 Thermo Fisher Scientific Inc All rights reserved For your future reference and when contacting the factory have the following information readily available It can be found on the data pla...

Page 3: ...trol Panel 6 Door Latch 6 USB WiFi Dongle 6 Thermal Printer Optional 6 Operating Standards 7 Installation 8 Selecting a Location 8 LN2 Connections 9 Electrical Connections 9 Sample Thermocouple Connection 9 Start Up 10 Power Up 10 Connectivity Requirements 10 Initial Start Up 11 Operation 16 Home Screen 16 Settings 17 Logs 23 ...

Page 4: ...ral Alarm Guidelines 34 Printer Set Up 37 Change the Paper 37 Specifications 38 Temperature Uniformity 38 Parts List 40 Accessories 40 PC Interface Software 42 Installation 42 Login 44 Setup 46 Run Operation 46 Typical Run Procedure 49 Manual Override Procedure 50 End Run 51 Print 51 Alarms 52 Power Failure Recovery 53 Display Control Summary 54 ...

Page 5: ...isinfect Controlled Rate Freezer Interior 67 Clean the Cabinet Exterior 68 Solenoid Valve Maintenance 68 Reset Heater Over temp Thermostat 68 Preventive Maintenance 68 Troubleshooting 70 Connectivity Troubleshooting 72 Appendix A User Role Summary 74 Appendix B City Time Zone 75 Warranty 82 Thermo Fisher Scientific PC and Peripheral Warranty 82 Thermo Fisher Scientific International Dealer PC and ...

Page 6: ...Thermo Fisher Scientific Controlled Rate Freezer Warranty 82 Thermo Fisher Scientific International Controlled Rate Freezer Dealer Warranty 83 Regulatory 84 21 CFR part 11 84 Contact Information 85 ...

Page 7: ...0V 50 60Hz CEE 7 7 TSCM34ML 100V 60Hz NEMA 5 15P TSCM48MA 48L 1 7 cu ft 120V 60Hz NEMA 5 15P 49 3 x 21 7 x 24 3 125 2 x 55 1 x 61 19 x 12 x 13 48 3 x 30 5 x 33 No Thermal Printer TSCM48MV 220V 50 60Hz CEE 7 7 TSCM48ML 100V 60Hz NEMA 5 15P TSCM17EA 17L 0 6 cu ft 120V 60Hz NEMA 5 15P 37 3 x 21 7 x 24 3 94 7 x 55 1 x 61 7 x 12 x 13 17 8 x 30 5 x 33 Built in Thermal Printer TSCM17EV 220V 50 60Hz CEE 7...

Page 8: ...gloves during the indicated procedures If performing decontamination procedures use chemically resistant gloves Use insulated gloves for handling samples and when using liquid nitrogen WARNING Unit weighs more than 50 lbs 22 7 kg Use proper 2 person lifting techniques when handling CAUTION This symbol indicates surfaces which may become hot during use and may cause a burn if touched with unprotect...

Page 9: ...tainers designed for low temperature liquids Cryogenic containers are specifically designed and made of materials that can withstand the rapid changes and extreme temperature differences encountered in working with liquid nitrogen Even these special containers should be filled SLOWLY to minimize the internal stresses that occur when any material is cooled Excessive internal stresses can damage the...

Page 10: ... If a person seems to become dizzy or loses consciousness while working with liquid nitrogen move to a well ventilated area immediately If breathing has stopped apply artificial respiration If breathing is difficult give oxygen Call a physician Keep warm and at rest If exposed to liquid or cold gas restore tissue to normal body temperature 98 6 F as rapidly as possible followed by protection of th...

Page 11: ...SB to Serial Adapter USB WiFi Dongle DPU S445 User s Guide Disk Optional accessible with thermal printer models Remove the Shipping Brackets Using a 7 16 wrench or socket remove the 4 lag screws attached to the shipping pallet Remove the 4 1 4 20 bolts to detach the 2 shipping brackets from the bottom of the unit Refer to the Figure 1 below Figure 1 Bottom view of the unit Note These are the unpac...

Page 12: ... an ON OFF switch as shown in Figure 2 Control Panel A 7 touch screen user interface is provided at front of the unit as shown in Figure 2 to control the unit Door Latch The door of the Controlled Rate Freezer is secured in the closed position with a vise action T handle latch as shown in Figure 2 The latch maintains positive compression of the door gasket against the Teflon heat break to prevent ...

Page 13: ...ned to operate under the following environmental conditions Indoor use Altitude up to 2000 m Ambient temperature 15 C to 35 C Humidity 20 85 non condensing Mains Supply Fluctuations 5 of nominal for better performance Installation Category II Pollution Degree 2 Class of Equipment I ...

Page 14: ...of water may drip out of the drain tube Figure 3 Rear view of the unit WARNING Nitrogen gas can cause suffocation without warning Store and use liquid nitrogen only in a well ventilated place As the liquid evaporates the resulting gas displaces the normal air in the area The cloudy vapor that appears when liquid nitrogen is exposed to the air is condensed moisture not the gas itself The issuing ga...

Page 15: ...aks Electrical Connections See the serial tag on the side of the unit for electrical specifications 1 Verify the ON OFF switch on the right side of the unit is OFF 2 Connect the appropriate line cord to the power inlet on the rear of the unit 3 Connect the unit to a grounded dedicated circuit Sample Thermocouple Connection 1 Open the unit door 2 Locate the thermocouple connector in the front upper...

Page 16: ...mobile tablet application from the AppStore or PlayStore Note InstrumentConnect allows you to monitor all connected instruments To access this section click on the InstrumentConnect icon indicated below Figure 5 InstrumentConnect Screen Note Users outside U S A Canada and Europe cannot access Connectivity with WiFi dongle Note Thermo Fisher Scientific connected devices support certification valida...

Page 17: ... the region press the Next button Figure 8 Region Setup Screen When entering your City into the Region Setup screen refer to Appendix B City Time Zone Follow the table to select the city closest to your time zone The next screen allows you to identify an individual Controlled Rate Freezer by specifying a Unit Name After entering a name press the Next button Figure 9 Unit Name Setup Screen The next...

Page 18: ...vigated to Wireless Setup Select a wireless network and press the Next button Figure 13 Wireless Setup Screen Once the intended network is selected highlighted you must press the Next button The following instructions are for WPA2 connection type Enter the network password and press the Next Figure 14 Wireless Setup Password Screen Note Press the eye icon on the screen for password visibility A su...

Page 19: ...onnect your unit to InstrumentConnect You can store historical data and receive alarm notifications to your InstrumentConnect account Figure 17 Connect to the InstrumentConnect Screen Connect via Mobile Device Selecting the Connect via Mobile Device option displays the following screen Follow the instructions to connect to InstrumentConnect Figure 18 Connect to the InstrumentConnect via Mobile Dev...

Page 20: ...The second screen provides information regarding LN2 Connections Press the Next button after reviewing Figure 22 Installation Instructions LN2 Connections Screen The third screen provides information regarding Other Setup and Calibration Press the Next button after reviewing Figure 23 Installation Instructions Other Setup Screen In the Add User Screen you can add a user by entering the user s Firs...

Page 21: ... Freezer Start Up 15 Figure 24 Add User Screen This screen indicates your initial setup is complete Press the Finish button to complete initial setup or the Back button to make changes Figure 25 Complete Setup Screen ...

Page 22: ... Run Last Run Last is a convenience feature that will navigate the user to the Run Information screen before allowing the user to start another run with the same profile of recently completed run Warming Mode Used to quickly warm up the chamber to 25 C and prepare for the next run After the chamber temperature reaches 25 C for 5 minutes the unit will buzzer for 10 seconds and hold the temperature ...

Page 23: ...er Users can access only the Printer Display and About options Chart Pressing the Chart button will navigate a user to the following screen Figure 30 Settings Chart Screen Here the visibility color and width of the chamber sample and profile series can be adjusted You can select the width of the series from the drop down between 2 to 5 with 2 being the lowest and 5 being the highest width dimensio...

Page 24: ...12 custom fields Custom Fields are used to provide additional metadata or details about a profile Figure 33 Settings Add Custom Field Screen Alarms When you select Alarms the following screen is displayed Figure 34 Settings Alarms Screen Here you can adjust the following parameters for the Tracking Alarm and Temperature Tracking Alarm Time From 1 3 5 10 minutes using the drop down menu Tracking Al...

Page 25: ... plot on the thermal printer chart printout You can also enable or disable the visibility of the Chamber Sample and Profile plots on the chart printout Select Save button to apply all changes Display When you select Display the following screen is displayed Figure 36 Settings Display Screen Brightness Use the slide control or the buttons to adjust the brightness level of the display Language To ch...

Page 26: ...is is used to set the country and city the Controlled Rate Freezer is operating from Figure 41 Settings Region Screen Display Off Allows the display to automatically be off from 9 PM to 6 AM Select Save button to apply changes Connectivity The Connectivity tab is used to setup a wireless network and connect to InstrumentConnect Be sure to follow both steps to store information on InstrumentConnect...

Page 27: ...isplayed After 5 seconds the interface will return to the previous screen If this occurs check the network status and re enter the correct password to establish the connection Tip use the eye icon to verify the password entry before attempting connection Refer to connectivity troubleshooting in Connectivity Troubleshooting section for additional support Figure 46 Wireless Setup Error Message Scree...

Page 28: ...ed to connect to InstrumentConnect Figure 51 Connect via 1 Time Pass code Screen Note When using the InstrumentConnect web and mobile app ensure you are in the correct regional environment If you are in China you should select the China region Refer to Section Connectivity Requirements for more details If the connection is successful via either of the two methods a success message is displayed If ...

Page 29: ... Log and Run Logs buttons Figure 54 Logs Screen Event Log All events that have occurred on the unit are recorded Run Logs Collection of all profiles that have been run on the unit Event Log When you press the Event Log button the following screen will display a list of the most recent events Figure 55 Event Log Screen A list of events that have occurred in the last 3 days in descending order will ...

Page 30: ...rd the exported logs If the device is not properly installed and or does not have enough storage space a warning message will be displayed as shown below Figure 58 Logs Export Warning Screen Run Logs When you press on the Run Logs button you will be navigated to the following screen Figure 59 Run Logs Screen A list of the most recent runs are visible Press on a run list entry to review the run Ref...

Page 31: ...0 C and a 10 C per minute cooling rate to a 90 C end temperature Preset _2 Commonly used for very small 96 well sample size resulting in a 1 C rate from nucleation to 40 C and a 10 C per minute cooling rate to a 90 C end temperature Preset_3 Commonly used for hemopoietic stem cells that are 65 100ml in size resulting in a 1 C rate from nucleation to 45 C and a 10 C per minute cooling rate to a 140...

Page 32: ...ust be set to one of the following commands available in the drop down menu Wait WAIT AT X X C SET TEMPERATURE Figure 63 Wait Command Wait maintains the specified chamber temperature indefinitely until the user selects the Advance button on the Active Run screen The temperature can be set over the 180 C to 50 C range with a setting resolution of 0 1 C Wait For WAIT AT CHAMBER X X C UNTIL SAMPLE Y ...

Page 33: ...ure at the beginning of the step Entry of a sign for the temperature ramp rate term is not allowed Hold HOLD X X C FOR Y Y MINUTES X X is the chamber set temperature and Y Y is the minutes Figure 66 Hold Command Maintains a specified Chamber temperature for the specified hold duration before proceeding to the next step The time can be set over a range of 1 to 99 minutes and the temperature can be ...

Page 34: ...last name Last Name should be more than two letters and should contain only alphanumerics Email Enter the user s email address Email should be in this format user domain com UserName Enter the username as required UserName should be more than 3 letters and alphanumerics no special characters are allowed in username Password Enter and confirm a user password The password entered should be 6 12 char...

Page 35: ...by pressing Update User Once a user has been set as Inactive that user can no longer log into the unit and perform operations Note There may be multiple users with admin privileges and there is no limit to the total number of users Calibration The sixth tab on the navigation bar is the Probe Calibration icon The following screen will be displayed once the Calibration icon is selected Figure 73 Cal...

Page 36: ...and return to the menu by pressing the back button in the top left as shown below Figure 76 Offset Result Screen Calibrate Probe Scale Factor Before starting the Scale Factor calibration insert both chamber and sample probes in LN2 Pressing Calibrate Probe Scale Factor will display the following screen A 5 minute timer will begin and the Scale Factor calibration will start Figure 77 Calibrate Prob...

Page 37: ... running profile Legend This view associates the series name and color Information Fields This view gives you the information about Date Time User Data Tag Profile Name Run File Name Note and any custom fields which you have entered before running a profile Alarm Details This view lists all alarms that have occurred during the run up to the current time When a profile is running and any alarm occu...

Page 38: ...Note Because so many factors affect the freezing and warming rates of a temperature profile see Specifications section all new user specific profiles should be verified for accuracy before applying to samples Run Review When the Run is completed you can review the Run by pressing the Prior Run Review on the Home screen or from Run Logs from Logs section Once you select a run for review you can see...

Page 39: ...ayed Figure 83 Export Run File Screen Select the File Type of the exported file to be either PDF CSV or RUN Press on Export button Note PDF is the only file format that is CFR21p11 compliant A pop up screen as shown below will be displayed indicating the export to USB was successful Figure 84 Logs Exported Screen ...

Page 40: ...d bell icon trigger the remote alarm and activate the buzzer in Idle mode All other alarms will only do so during Warming mode or an active run Chamber Thermocouple Failure If the chamber thermocouple cannot be detected or reads erroneous values 75 C an alarm will be triggered according to the general alarm guidelines A chamber thermocouple failure is considered a non clearing alarm and will end W...

Page 41: ...terminate Once the failure is detected a dialog will prompt the user to acknowledge the alarm Upon acknowledgment the Controlled Rate Freezer will return to the home screen and enter Idle mode A RUN file will be written as if the run was canceled early Heater Malfunction If the heater is energized continuously no active temperature control for 60 minutes or longer the Controlled Rate Freezer will ...

Page 42: ...ture the alarm will clear Power Failure If AC power to the Controlled Rate Freezer is interrupted the Controlled Rate Freezer will detect the power failure and alert the operator that the Controlled Rate Freezer is under battery power The freezer will generate a Power Failure alarm according to the general alarm guidelines Active Run If an active run is ongoing when the alarm occurs the run will c...

Page 43: ...open button to open the paper cover Figure 91 Paper cover open button 3 Install the paper roll into the paper holder Make sure that at least 5cm of thermal paper protrudes from the paper outlet Figure 92 Install the paper roll to the paper holder 4 Press both sides of the paper cover to close the paper cover Figure 93 Close the paper cover 5 If a paper roll with a mark is used press the FEED switc...

Page 44: ...ples placed on the canister surface under 250ml cryo bag that is filled with 50ml 10ml cryo media DMEM in each bag with the cryo bags distributed in standard racks and canisters as shown in Figure 95 separately for each cabinet size Each standard rack contains 10 shelfs where each shelf is loaded with a cryo bag inside a canister 3 shelfs are instrumented with type T Thermocouples i e the second f...

Page 45: ...oor interlock switch turns off LN2 heater and fan motor except during the warm up cycle During the warm up cycle the door can be opened with heater and fan running to accelerate warming LN2 pressure relief valve located adjacent to LN2 connection Chamber pressure vent port located on left side wall Heater over temperature protection At a temperature level of 93 C an independent manual reset device...

Page 46: ...1301H01 Thermal Data Printer 430326 Cord set 13A 125V 16 3 USA 430109 Cord set 10A 250V European 370248 T C Plug Type T Table 6 Freezing Racks and Holders Catalog No Description 4000294 Straw Rack for 25 5ml straws holds 40 straws per rack 4000303 Cane freezing rack large 4000700 Cane freezing racks small 4000701 1 2 2ml freezing rack small 4000702 Rack holder for 4000701 racks small 4000703 1 2 2...

Page 47: ... 2 2ml vials 4000386 Thermocouple sensor for 4 5ml vials 4000384 Thermocouple sensor 02 sheath for straws 4000393 Thermocouple sensor ribbon type for bags Table 9 Canisters for Freezer Racks Catalog No Description 1950831 Swing arm canister for 25ml bag 4000610 Swing arm canister for 50ml bag 4000356 Swing arm canister for 200ml bag 4000357 Swing arm canister for 700ml bag 4000335 Sliding arm cani...

Page 48: ...e communicates with the freezer to collect information such as run data and any alarms The Controlled Rate Freezer companion PC software is optimized to work with Windows 7 8 or 10 A PC with Windows 7 8 or 10 can communicate with up to four CRF units However our recommendation is to use a dedicated PC for each CRF If multiple instances of the software are open and connected to different CRF units ...

Page 49: ...Figure 99 Additional Tasks Screen 7 Allow the installation to complete After installation is complete it checks for the Java version 1 8 and higher in the PC If the required Java version is not available it installs the Java bundled with the PC Interface If it detects Java 1 8 and higher versions then it does not install the Java bundled with the PC Interface 8 If Java Runtime Environment is eithe...

Page 50: ...s shown below Figure 102 Figure 102 Verify COM Ports Screen 14 To complete the PC software installation first check the Launch PC Interface window Then select Finish Figure 103 Launch PC Interface window Login The icon at right appears in the default directory after the application is successfully installed As the PC interface program begins a splash screen Figure 104 appears with user access to t...

Page 51: ...an be alphanumeric from third character onwards User name cannot have spaces or linefeed Please enter User name message displays if User name field is blank Password Requirements Password length must be between 8 to 12 characters The Password should contain combination of minimum one Uppercase A Z Lowercase a z Number 0 9 and special characters The message Please enter Password displays if Passwor...

Page 52: ...he freezer displaying the sample temperature and chamber temperature Freezing Profiles are displayed in a graph Press Ctrl Mouse Left Right button to pan around graph The Run screen enables the user to perform the following commands Open profile Displays the predefined and user created freezer profiles Start Run Enables the user to run the freezing profile End Run Allows the user to end the run co...

Page 53: ...is user login user name and is auto populated Profile Name Indicates the profile selected prg file by the user for the run Sample type Enter the type of sample being frozen The description cannot exceed 20 characters Note Profile Name Date Time and Operator fields are not editable by user Profile Steps Figure 109 Profile Steps Profile steps display all the profile commands of a freezing profile No...

Page 54: ...gresses X axis displays time in Minutes Default setting for X axis is 1 minute Y axis displays temperature in degrees Celsius C Default setting for Y axis is 5 C Allows the user to zoom in and out Graph is adjusted based on the temperature selected Press Ctrl Mouse Left Right button to pan around graph Graph Legend The Graph Legend displays the different plot colors at upper right side of the grap...

Page 55: ...ue box pops up it is recommended to browse to your desired directory or type in the full path case sensitive Network drives are prone to connection failure which could cause data loss during profile Run data storage It is recommended to use a local drive to store profile Run data 11 Click Save The profile is saved in the directory selected 12 Program waiting for user click here to continue will ap...

Page 56: ...he data capture Choose Continue capturing data or Stop capturing data No other commands can be sent from the PC iv Program loading error The download program cannot be validated This message appears after the download profile fails to validate initial validation and three re tries The user must open a profile again and initiate the run v Communication error A CRF was not found This message appears...

Page 57: ...t enter a password to confirm end run Figure 131 Password Invalid Figure 132 Run Terminated 3 Displays a pop up window if an incorrect password is entered 4 Click OK and enter the correct password to terminate a profile run A window appears showing Profile run terminated Click OK to close i Remote Mode button will turn white after profile run is terminated ii Unit Connection status will turn to Un...

Page 58: ...ear Figure 134 Click to Silence Figure 135 Clear Alarm Click anywhere on the alarm window to silence the audible alarm at the freezer After the audible alarm is silenced another alarm window appears showing the list of three most recent alarms and the message Click Here To Clear Click anywhere on the alarm window to clear all alarms that have been resolved The alarm window reappears if any alarms ...

Page 59: ...n the power is restored However the freezer runs in Stand alone mode All commands from the PC are ignored except for profile status requests The temperature data is continually captured and plotted The PC cannot clear alarms or stop the Run The UI of the freezer remains disabled The Run can be aborted at the freezer by pressing the Abort button in the remote dialog box The freezer resumes the cont...

Page 60: ...a freezing profile Edit Policy Wait Command Range Temperature values must be between 50 C to 180 C Wait For Temperature Command Range Temperature values must be between 50 C to 180 C Wait For Temperature Command Sample Temperature value must be min 1 C greater than Chamber Temperature value Ramp Command Range The rate of freezing must be between 0 1 C to 99 9 C and temperature values must be betwe...

Page 61: ...mp rate and Y Y is the chamber or sample endpoint temperature Figure 142 Ramp Command This step changes Chamber temperature from its current value to specified temperature chamber sensor trip point at the selected rate C minute The rate can be set over a range of 0 1 C minute to 99 9 C minute The temperature can be set over a range of 180 C to 50 C 0 1 C When the chamber reaches specified temperat...

Page 62: ...wait for hence it cannot be created automatically for every run Wait or wait for command increases the TEMPERATURE of LN2 and is the mandatory first step It is required to purge the warm LN2 plumbing prior to initiating controlled rate freezing This step is not available for deleting or changing to a different step type 3 If the user selects WAIT command the CRF chamber waits at 0 C or at user def...

Page 63: ...sed to delete a step 6 Delete All button is used to delete all steps of a profile When the user clicks the Delete All button a confirmation window is displayed as shown below Figure 149 Delete all Confirmation 7 New steps will be inserted at the position highlighted in the program listing window 8 Subsequent steps will move down one position as new ones are added 9 Selecting the step type and ente...

Page 64: ...ring an edit profile are as follows Note All the fields that are not relevant to current running step will be disabled For example if a loop operation is running then the steps related to Wait Wait for etc will be disabled Table 11 Error Messages Error Message Description When the user tries to replace the first step Can t replace first step This message appears if the user tries to replace the fi...

Page 65: ...e File already exists This message appears when the user is trying to save a profile with an already existing name When the user tries to give the time value outside of the range 1 to 99 minutes in Hold Command Table 11 Error Messages Error Message Description Invalid time value is entered Time value must be between 1and 99 minutes This message appears when the time value is outside the range of 1...

Page 66: ... graph plot The screen shown in the figure below will appear once the user clicks Open and selects the required run file Press Ctrl Mouse Left Right button to pan around graph Figure 153 Review Profile Screen User Controls Review This screen enables the user to review a freezer profile When the user opens a run file to review the properties of a freezer profile are populated automatically Note A c...

Page 67: ... details First run file name Date and time of profile executed Information fields Cryoprotectant media sample type custom fields Notes entered by user Page number and Thermo Scientific logo Page 2 contains Printed date and time as header Profile steps Alarms occurrence and its information Page number and Thermo Scientific logo Page 3 contains Printed date and time Controlled Rate Freezer review co...

Page 68: ...aded if the data is available in run file 6 Sample Type a Initially will be blank b Populates the sample once the Run file is loaded if the data is available in run file 7 Data Tag a Initially will be blank b Populates the Data Tag once the Run file is loaded 8 Custom fields if added by the user a Initially will be blank b Populates the Custom fields data once the Run file is loaded if the data is...

Page 69: ...o set default directories 1 Click Default profile Directory folder icon The Open window dialog box appears 2 Select the path of the directory and click Open 3 Click Default Run Directory The Open window dialog box appears 4 Select the path and click Open When selecting the file path it is recommended to browse to your desired directory or type in the full path case sensitive 5 Click Save The defau...

Page 70: ...nt A user can also delete his account but only if the run initiated by that user has completed If all the user accounts are deleted then Anonymous mode will be activated automatically Password Policies Password length must be between 8 to 12 characters Password can contain any combination of minimum one Uppercase A Z Lowercase a z Numbers 0 9 Special characters Changing a user s password will requ...

Page 71: ...any special character or numerical value It must start with a letter only Information Field name can contain a special character as the second character or thereafter Default information fields are Profile Name Data Tag Date Time Operator Cryoprotectant Media and Sample Type The additional fields are stored in properties file All fields including default Information fields are maximum of 20 charac...

Page 72: ...zer Help The Help section assists the user in navigating through the PC Software Figure 164 Help File About This section provides information for Thermo Fisher the OS compatibility and the software version of the application Figure 165 Information ...

Page 73: ...and can be cleaned 4 Clean the interior of the unit with an appropriate disinfectant Clean rinse and wipe dry as needed Clean the screened side ducts and center ducts before reinstalling 5 Press the top and bottom edges of the center duct toward each other and insert the duct into the center of the chamber The edges fit inside the door gasket 6 Install each screened side duct Locate the tabs on th...

Page 74: ...operation if the sidecar temperature exceeds 92 C If this occurs a service technician will be required to reset the thermostat to resume normal operation Preventive Maintenance Your equipment has been thoroughly tested and calibrated before shipment Regular preventive maintenance is important to keep your unit functioning properly The operator should perform routine cleaning and maintenance on a r...

Page 75: ...y Table 13 Preventative Maintenance Requirements Action Each Use Daily Weekly Monthly Yearly Dry door and chamber opening gasket and heat breaks Disinfect chamber interior Clean cabinet exterior Check calibration of internal and sample probes Battery Inspect solenoid valve ...

Page 76: ...2 solenoids bad Check for valve counter warning dialogue after run completion Contact service to replace valves Erratic Chamber Temperature High LN2 Pressure Verify tank pressure regulator 22 nominal Replace Fill LN2 Tank Chamber Thermocouple Mounting Verify that the chamber temperature probe is properly seated in the sleeve by verifying the blue marking is flush with the frame Refer to calibratio...

Page 77: ...code table and take appropriate action PC Interface Login Errors Refer to PC Interface Login Error Messages section of manual Refer to PC Interface Login Error Messages section of manual COM Port Error Refer to PC Interface Installation section of manual Refer to PC Interface Installation section of manual USB Exporting Drive file system format Verify drive is compatible of file system format ex F...

Page 78: ...ice Freezer will not connect to a Wireless Network SSID Invalid SSID and or Password Verify that you are connecting to the correct network SSID and are entering the correct password Suggestion attempt the same network connection via an alternate device like a cell phone laptop or tablet Try restarting the freezer and re attempt to establish the WiFi connection Network SSID requires user acceptance...

Page 79: ...losed Verify with local IT that ports 443 123 and 80 are open to the Internet in the facility s firewall Use the Telnet app from a computer on the same network Telnet is NOT enabled by default in Windows telnet apps thermofisher com 443 telnet apps thermofisher com 123 Connect device to cloud using 3G 4G hotspot Confirm if the hotspot works at the unit location and allows internet connection using...

Page 80: ...xport reports No restrictions able to view and export reports Log Review No restrictions able to view and export reports No restrictions able to view and export reports No access Profile Able to select and start a run Able to modify a custom profile Able to create a profile Able to select and start a run Able to modify a custom profile Able to select and start a run User Able to view all users ina...

Page 81: ...akchott Ouagadougou Africa 01 00 Algiers Bangui Brazzaville Ceuta Douala Kinshasa Lagos Libreville Luanda Malabo Ndjamena Niamey Porto Novo Sao_Tome Tunis Africa 02 00 Gaborone Harare Johannesburg Khartoum Kigali Lubumbashi Lusaka Maputo Blantyre Bujumbura Cairo Maseru Mbabane Tripoli Windhoek Africa 03 00 Juba Kampala AddisAbaba Asmara DaresSalaam Djibouti Mogadishu Nairobi America 00 00 Danmarks...

Page 82: ...Caracas Cuiaba Curacao Dominica GlaceBay GooseBay GrandTurk America 04 00 Grenada Guadeloupe Guyana Table 17 City Time Zone Time Zone City Halifax Kralendijk LaPaz LowerPrinces Manaus Marigot Martinique Moncton Montserrat PortofSpain PortoVelho PuertoRico Santiago SantoDomingo StBarthelemy StKitts StLucia StThomas StVincent Thule Tortola America 05 00 Atikokan Bogota Cancun Cayman Detroit Eirunepe...

Page 83: ...ridgeBay Chihuahua Creston Table 17 City Time Zone Time Zone City DawsonCreek Denver Edmonton FortNelson Hermosillo Inuvik Mazatlan Ojinaga Phoenix Yellowknife America 08 00 Dawson LosAngeles Tijuana Vancouver Whitehorse America 09 00 Anchorage Juneau Metlakatla Nome Sitka Yakutat America 10 00 Adak Antarctica 00 00 Troll Antarctica 03 00 Syowa Antarctica 05 00 Mawson Antarctica 06 00 Vostok Antar...

Page 84: ...abat Dushanbe Karachi Oral Samarkand Tashkent Yekaterinburg Asia 05 30 Colombo Kolkata Table 17 City Time Zone Time Zone City Asia 05 45 Kathmandu Asia 06 00 Almaty Dhaka Omsk Qyzylorda Thimphu Urumqi Asia 08 00 Brunei Choibalsan HongKong Irkutsk KualaLumpur Kuching Macau Makassar Manila Shanghai Singapore Taipei Ulaanbaatar Asia 08 30 Pyongyang Asia 09 00 Chita Dili Jayapura Khandyga Seoul Tokyo ...

Page 85: ... BrokenHill Darwin Australia 10 00 Brisbane Currie Hobart Lindeman Melbourne Sydney Europe 00 00 Dublin Guernsey IsleofMan Jersey Lisbon London Europe 01 00 Amsterdam Andorra Table 17 City Time Zone Time Zone City Belgrade Berlin Bratislava Brussels Budapest Busingen Copenhagen Gibraltar Ljubljana Luxembourg Madrid Malta Monaco Oslo Paris Podgorica Prague Rome SanMarino Sarajevo Skopje Stockholm T...

Page 86: ...06 00 Chagos Indian 06 30 Cocos Indian 07 00 Christmas Pacific 11 00 Midway Niue Table 17 City Time Zone Time Zone City PagoPago Pacific 10 00 Honolulu Johnston Rarotonga Tahiti Pacific 09 30 Marquesas Pacific 09 00 Gambier Pacific 08 00 Pitcairn Pacific 06 00 Easter Galapagos Pacific 09 00 Palau Pacific 10 00 Chuuk Guam PortMoresby Saipan Pacific 11 00 Bougainville Efate Guadalcanal Kosrae Norfol...

Page 87: ...Controlled Rate Freezer Appendix B City Time Zone 81 Pacific 13 00 Apia Enderbury Fakaofo Tongatapu Pacific 14 00 Kiritimati Table 17 City Time Zone Time Zone City ...

Page 88: ... and preventive maintenance Thermo shall not be liable for any indirect or consequential damages including without limitation damages relating to lost profits or loss of products Your local Thermo Sales Office is ready to help with comprehensive site preparation information before your equipment arrives Printed instruction manuals carefully detail equipment installation operation and preventive ma...

Page 89: ...ur equipment are allowed an additional six months for delivery and installation provided the warranty card is completed and returned to the Technical Services Department During the first year component parts proven to be non conforming in materials or workmanship will be repaired or replaced at Thermo s expense labor excluded Installation and calibration are not covered by this warranty agreement ...

Page 90: ...ions not expressly approved by the party responsible for compliance could void the user s authority to operate the equipment Note This equipment has been tested and found to comply with the limits for a Class A digital device pursuant to part 15 of the FCC Rules These limits are designed to provide reasonable protection against harmful interference when the equipment is operated in a commercial en...

Page 91: ...mofisher com cold or call Countries Sales North America 1 866 984 3766 China 800 810 5118 Japan 03 6832 9300 Countries not listed 49 6184 90 6000 Thermo Fisher Scientific Asheville LLC 401 Millcreek Road Marietta Ohio 45750 United States Find out more at thermofisher com cold 2020 Thermo Fisher Scientific Inc All rights reserved All trademarks are the property of Thermo Fisher Scientific and its s...

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