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Cedex HiRes Analyzer

Addendum 2 to
Operator’s Guide, Version 1.0

Software Version 2.2.1

August 2012

For life science research only.
Not for use in diagnostic procedures.

Summary of Contents for Cedex HiRes

Page 1: ...Cedex HiRes Analyzer Addendum 2 to Operator s Guide Version 1 0 Software Version 2 2 1 August 2012 For life science research only Not for use in diagnostic procedures...

Page 2: ...hesitate to contact your Roche Diagnostics representative To call write fax or email us visit the Roche Applied Science home page http www roche applied science com and select your home country Count...

Page 3: ...Cedex HiRes Analyzer Addendum 1 to Operator s Guide Version 1 0 Software Version 2 2 1 January 2012 For life science research only Not for use in diagnostic procedures...

Page 4: ...des c Updated information about the procedure for removal reinstallation or replacement of the syringe If you have any further questions regarding this matter please do not hesitate to contact our Tec...

Page 5: ...nsity Reference Standard Beads to check the calibration and confirm that the FlowFactor is correct If necessary adjust the FlowFactor To perform the Cedex HiRes System calibration check and FlowFactor...

Page 6: ...ofer Stra e 116 68305 Mannheim Germany 2012 Roche Diagnostics All rights reserved www roche applied science com 06638597001 0112 For life science research only Not for use in diagnostic procedures CED...

Page 7: ...Cedex HiRes Analyzer Operator s Guide Software Version 2 2 1 May 2011 For life science research only Not for use in diagnostic procedures...

Page 8: ......

Page 9: ...ex HiRes System 25 2 Choosing a Suitable Location 26 2 1 Connecting or disconnecting the device 26 3 Connecting Hardware Components 27 3 1 Completing the Windows Mini setup 27 4 Installing Cedex HiRes...

Page 10: ...ysis Process Parameters 52 3 3 Preparing the Sample and Attaching it to the Multi Sample Tray or Sample Port 53 3 3 1 Starting the Measurement 53 3 3 2 End of Measurement 54 3 4 Interrupting a Measure...

Page 11: ...ion Time Chart 85 5 1 Creating a CTC View 85 5 1 1 The View Area 86 5 1 2 The Series of Measurements Belonging to Selected View Area 86 5 1 3 Adding Measurements to a View 87 5 1 4 Editing Measurement...

Page 12: ...Sampler DefaultCup 107 7 4 3 Turning off Automatic Incrementation of Sample Cup Position 107 7 4 4 Turning off the Flow Chamber Prescan 108 7 4 5 Error Level Displayed to Users 109 7 4 6 Liquid Conta...

Page 13: ...of the Syringe Guide and Spindle 132 6 Maintenance of the Flow chamber 8 Way Valve and the remaining Hardware Components 133 7 Operational Data 133 8 The System Suitability Test SST 134 8 1 Creating...

Page 14: ...8 Cedex HiRes Analyzer Operator s Guide...

Page 15: ...or s Guide can be directed to your local Roche Diagnostics representative Every effort has been made to ensure that all the information contained in the Cedex HiRes System Operator s Guide is correct...

Page 16: ...Res Software will result in invalidity of the guarantee and service contract V Trademarks CEDEX and INNOVATIS are trademarks of Roche Other brands or product names are trademarks of their respective h...

Page 17: ...nd conditions of this Agreement In addition Licensee must ensure that the copyright notice is maintained on the Software transferred Licensee may not a Use the Software in whole or in part except as e...

Page 18: ...in material and workmanship Licensee may terminate this Agreement by returning the Software and a copy of Licensee s receipt to Supplier and Licensee s money will be refunded IN NO EVENTWILL SUPPLIER...

Page 19: ...expire 9 Import Export and Use of the Software Licensee shall be exclusively responsible for ensuring compliance with the relevant legislation relating to its rights to import export or use the Softw...

Page 20: ...uding the correct placement of the reagents and disposables and instructions for carrying out single and multiple measurements of cell samples Chapter D Software provides a detailed description of the...

Page 21: ...ectives relevant for this analyzer XII FCC Notification Changes or modifications to this unit not expressly approved by the party responsible for compliance may void the user s authority to operate th...

Page 22: ...ners Clean the containers before reusing them Always observe the safety regulations when handling Trypan Blue Detergent Cleaning Solution or acids and bases Waste contaminated with tissue or cells e g...

Page 23: ...de or outside the instrument could be hazardous Under no circumstances should the user attempt to modify or deliberately defeat the safety features of this instrument If the power cord becomes cracked...

Page 24: ...18 Cedex HiRes Analyzer Operator s Guide...

Page 25: ...is software Operator is adjusted Graphical representations of the measurement results can be viewed in the Measurement Statistics Histogram Diameter Histogram Compactness Histogram Aggregate Histogram...

Page 26: ...tch Figure 1 The Cedex HiRes Analyzer The analyzer consists of two main components the hardware for image capturing scanner and the Liquid Management system The flow chamber is specially developed to...

Page 27: ...on via the capillary tubes and the 8 way valve into the precision flow chamber an image of which is scanned with the scanner The scanned image of the flow chamber is then cut up into smaller images fo...

Page 28: ...nd identifies particles thus differentiating cells from cell debris and dirt particles Live and dead cells are differentiated according to their degree of Trypan Blue staining The image processing is...

Page 29: ...Pixel Chamber height 100 m Material and diameter of the capillaries Teflon 765 m Operating temperature Optimal image quality is achieved between 20 C and 30 C 10 to 40 C Maximum temperature change 5 C...

Page 30: ...ded 80 GB USB 2 free ports Firewire 1 free port 400 Mbps with 4 or 6 contacts CD DVD burner Minimum CD burner required DVD burner recommended if computer will not be connected to a server Graphic card...

Page 31: ...if desired before the service technician assembles the Cedex HiRes System The Cedex HiRes System is assembled by a service technician authorized by Roche Diagnostics GmbH The service technician insta...

Page 32: ...must be done after transportation see Automatic Adjustment and Alignment Verification Injury from heavy loads The Cedex HiRes Analyzer weight is 29 kg 63 8 lbs No attempt should be made by the user to...

Page 33: ...ng convention If you are not sure leave it as it is The name can be changed at any time later on Computer description This is a purely informational field that helps to identify the Control Unit in a...

Page 34: ...tab The value for the ChamberHeight is located in the System Options menu under the Hardware tab See the chapter System Options and User Preferences in the Appendix for more information The Cedex HiRe...

Page 35: ...f this occurs proceed according to the directions in the chapter Updating Older Cedex HiRes Software version 2 x to Cedex HiRes Software 2 2 5 Click on Next in the Setup window shown below Figure 8 6...

Page 36: ...nstallation Folder window shown below choose the folder recommended by the program Ensure that the option Install Cedex 2 2 for Everyone is selected then click on Next Figure 11 9 In the following win...

Page 37: ...he database access a database user CEDEXUSER is automatically created with that password Write down the password for future reference b Enter the serial number of your Cedex HiRes Analyzer c Verify th...

Page 38: ...Cedex Server can be configured so that it starts automatically when the computer is turned on To configure the Cedex Server to autostart do the following 1 Open a Windows explorer window by right clic...

Page 39: ...rol Center 8 Open the Diagnosis window via the Setup menu of the Cedex Control Center and verify the configuration of the system For a Cedex HiRes Analyzer with Multi Sampler there must be a module AS...

Page 40: ...the size of this folder Enough time is scheduled for a backup of the current installation approximately one hour for backup to a fast external hard drive per 10 GB disk space used in the Cedex 2 direc...

Page 41: ...ion the field under to the Cedex 2 directory must be changed to the appropriate pathway Change the Cedex 2 database file if it is not C Cedex2 DB CEDEX FDB by clicking on the change button next to Ced...

Page 42: ...stallation the message below will appear Confirm by clicking on the OK button Figure 26 11 The update process can now be started Click on the Update current installation to version 2 2 1 button as sho...

Page 43: ...ng a Cedex HiRes Software 2 Backup This procedure should only be carried out in case a failure occurs during installation of the Cedex HiRes Software 2 2 update as described in Updating to Cedex HiRes...

Page 44: ...2 folder by right clicking on it and selecting Delete Figure 32 2 Confirm the upcoming message by clicking on Yes Figure 33 3 Locate the folder where the backup of the Cedex2 folder and database has b...

Page 45: ...edex HiRes System must be switched on before the analysis software can be started otherwise the software will not be properly initialized After the initial installation switch on the individual device...

Page 46: ...s are available after installation a Superuser password spass b Administrator password apass For the Cedex HiRes Software there should generally be at least three levels of users In addition to normal...

Page 47: ...he menu bar at the top of the Control Center has 7 menu items System menu Measurements menu Functions menu Reports menu Master Data menu Setup menu Help menu 1 2 System Menu The menu items have the fo...

Page 48: ...gent left Confirmation of a reagent change is also executed via this window Operational Data The operating hours number of measurements and liquid consumption are tracked in this window Cleaning Routi...

Page 49: ...individually set using this window Cell Type List This allows for the creation of customized Cell Types 1 7 Setup Menu Clicking on these menu items will open up windows with the following functions A...

Page 50: ...n Time Charts SST Opens the System Suitability Test List window for setting up and executing SSTs Clean Opens the Cleaning window HWM Opens the Hardware Management window Log Out Logs the user out of...

Page 51: ...clicking the Cedex Client icon on the desktop the Cedex Server must be started before the Cedex Client can be started The Log In window of the Cedex HiRes Analyzer program will open 3 Enter the usern...

Page 52: ...ay a Prime is necessary prior to the first measurement of the day No measurement is possible without performing a Prime first If a measurement is attempted before the machine has been primed an error...

Page 53: ...rs in the appropriate positions in the reagent tray see Figure 38 below 6 Close the front cover by pulling it all the way down When the front cover is closed the capillaries are automatically correctl...

Page 54: ...ounts in the containers or space available in the waste container The reagent control function that monitors reagent and waste levels can be turned off See Disabling the Reagent Control for more infor...

Page 55: ...Blue is completely used up during measurements and then refilled a Prime must be performed again before running the next sample see Performing a HW Startup and Prime If a Prime is not performed the Pr...

Page 56: ...ies must be specified in the Measurement window prior to carrying out measurements They include Choosing the operating mode and specifying sample data Defining the measurement and analysis process par...

Page 57: ...lly unless a different Sample ID is desired 4 If desired use the Sample Drawing drop down menu to select the date when the sample was drawn Note that the process date and time i e the date and time th...

Page 58: ...Center window However there will be no effect on the measurement procedure other than a slightly longer sedimentation time The sedimentation time can be increased for the Std Size and Max Size if desi...

Page 59: ...cluding the sample is ready for a measurement as follows 1 Ensure that the Cedex Sample Cup is correctly placed in the Multi Sample Tray or attached to the sample port 2 Ensure that the reagent contai...

Page 60: ...rocedure automatically begins immediately after the scanning ends The entire Liquid Management system is rinsed during this procedure Ultra Fast Clean Once this procedure has been completed a green ba...

Page 61: ...with an LM Shutdown procedure to maximize the life span of the Cedex HiRes Analyzer and guarantee optimal performance The entire Liquid Management system is rinsed with distilled or de ionized water...

Page 62: ...ampler is part of the Cedex HiRes Analyzer see Figure 42 and Figure 43 The Multi Sampler can convey up to 20 cell suspension samples in sequence to the Cedex HiRes System for analysis Once the samples...

Page 63: ...Multi Sample Tray An empty Cedex Sample Cup must be manually placed in the position set for the DefaultCup before running LM Shutdown focus adjustment Prime and all cleaning routines The position in...

Page 64: ...safety precaution leave all of the empty Cedex Sample Cups in the Sample Tray after the measurements have been completed 4 2 2 Ejecting the Multi Sample Tray The Multi Sample Tray can be ejected by g...

Page 65: ...to Cedex Sample Cups and place the cups in the desired locations on the Multi Sample Tray 2 Click anywhere in the row of the MultiRun Measurements Preparation area that corresponds to the location of...

Page 66: ...the Multi Run preparation area Confirm the safety query with Yes to accept the modification 3 After some or all rows have been activated click on the Start button on the right hand side of the Multi...

Page 67: ...ith this status The row is highlighted in yellow Measure Indicates that the system is in the middle of carrying out a measurement of the sample marked with this status The row is highlighted in yellow...

Page 68: ...and the row for that sample is left in edit mode the cup will be used for a cleaning routine should one be scheduled to be carried out at that time It is therefore critical to ensure that a Cedex Sam...

Page 69: ...the Stop button to pause or stop the Multi Run If a measurement is being carried out when the Stop button is pressed that measurement will be completed All scheduled measurements status scheduled wil...

Page 70: ...nts carried out by the user logged into the system mine measurements that have not yet been printed out unprinted and or measurements carried out on that particular day today Measurement results can b...

Page 71: ...huts down several elements of the hardware system including the scanner Multi Sampler and pump Follow the instructions below to carry out an LM Shutdown 1 Click on the HWM button in the Shortcuts area...

Page 72: ...ts are in progress 5 3 Shutting down the Control Center Follow the instructions below 1 Perform an LM Shutdown to shut down the Liquid Management system see Carrying out an LM Shutdown 2 Shut down the...

Page 73: ...ure 48 See Using the Measurement List for more details about working with the Measurement List Figure 48 Measurement List window To see the results of a particular measurement highlight the row contai...

Page 74: ...and dead cells Total Cell Count This value indicates the total number of cells counted Avg Compactness Value This value indicates the average variation in shape of viable cells from an ideal sphere w...

Page 75: ...rocessed the original or reprocessed data can be selected in the drop down menu of the Data Set section If data has been reprocessed at some point the Effective checkbox will indicate which data set h...

Page 76: ...rea click on a different row in the Result Data area Only one image is displayed in the Image area in the Measurement window Alternatively an overview of all cell images can be displayed by clicking o...

Page 77: ...ysis using the Live Operator The Image View offers the following information and options Viable Cells number of viable cells Dead Cells number of dead cells Show Circles check box switches on off the...

Page 78: ...clusion and inclusion of images for a particular measurement are done via the check box in the Excluded column in the Result Data area of the Measurement window If there is a check in the Valid check...

Page 79: ...n be accessed via the View Prescan button located in the Image area of the Measurement window To open an Image View window containing the Prescan image do the following 1 Click on the View Prescan but...

Page 80: ...rmation about some results If there is no check in the Show measurement results box at the bottom left hand corner of the window sample and process parameters for measurements are displayed see Figure...

Page 81: ...tton next to the date in order to select the desired ending date 4 Once the dates for filtering the measurements have been selected click on the Find button in the upper right hand corner of the Measu...

Page 82: ...n the Shortcuts area of the Cedex Control Center or by selecting the Measurement List option in the Measurements menu of the Control Center 2 Highlight the row of the measurement to be reprocessed and...

Page 83: ...t is labeled the Effective data set by doing the following 1 Select the data set version of the measurement to be labeled Effective in the Measurement List window 2 Click on the Reprocess button A Mea...

Page 84: ...anually by the user see Excluding Images from the Evaluation Process Including Excluded Images 4 1 Enlarging the Histograms Certain areas of the histograms can be enlarged by following the instruction...

Page 85: ...s each aggregate is composed of Both the actual cell number and the percentage distribution can be displayed Figure 55 The Aggregate Histogram detailed view divided into living and dead cells here abs...

Page 86: ...ber of cells per aggregate is given on the x axis Figure 56 shows for example that 3 66 of all living cells and 7 29 of all dead cells are found in aggregates of two cells The Total Cell Count living...

Page 87: ...f living and dead cells Here percentage 4 3 Cell Diameter Histogram Clicking on the Cell Diameter Histogram button will bring up the Cell Diameter Histogram The Cell Diameter Histogram represents livi...

Page 88: ...of each slider The borders of the first interval are defined by the minimum value and the first numerical value entered The next two values define the upper borders of the second and third intervals...

Page 89: ...Histogram button to display a diagram that compares viable cell shapes to that of an ideal sphere If a significant number of cells ordinate have a high value this could indicate improper handling of...

Page 90: ...top of the green bars The Combine button which appears when the Measurement Statistics histogram is open can be used to combine several images to give a better overview of the whole sample Conspicuous...

Page 91: ...d viewed edited exported and deleted A collection of data used for the creation of a particular chart is called a View Each View can have up to 5 separate series of measurements for comparison of data...

Page 92: ...nter the desired parameters and click on the Find button When searching by date the check box next to the date must first be checked After checking the box clicking on the drop down menu to the right...

Page 93: ...e IDs associated with that particular Reactor ID will appear in the upper section of the Selection of Data Series window 5 Click on the empty column to the left of the measurement to be added to the s...

Page 94: ...for a series that are marked with a in the checkbox of the Use column will be displayed in the Cultivation Time Chart Should it not be desirable to display a particular single measurement the measurem...

Page 95: ...tivation Time Chart Once a View has been created with the desired series of measurements to be used for a chart the Cultivation Time Chart can be created To create a Cultivation Time Chart do the foll...

Page 96: ...ts counted Click on the appropriate checkboxes to select the desired values Figure 66 Cultivation Time Chart window The measurement series including information about which measurements have been used...

Page 97: ...area displays the offset set by the user the button displays 0 h if an offset was not set Clicking on this button opens the Measurement Offset window The measurement series offset can be then manuall...

Page 98: ...rameters Specific Growth Rate and Doubling Time T of the culture are computed by means of the differential curve Click on the to close the Exponential Regression window The CTC Views window will reapp...

Page 99: ...umber of measurements and liquid consumption Measurement data Contains information about measurement parameters and calculated results e g sample identification data name and parameters of the Cell Ty...

Page 100: ...s 5 In the Location area the target path to be used for storage of the export file is entered The button on the right of the entry field opens a window in which the path can be directly selected The n...

Page 101: ...n the Export To External DB window 5 Enter the path under which the export file should be stored in the Location area Alternatively the button on the right of the entry field opens a window in which t...

Page 102: ...y clicking on It is not possible to import more than 200 measurements at one time A default entry for the path under which the import file should be stored can be entered in the System Options under t...

Page 103: ...the entry ResultsToShowInList located under the Measurement List Default Filter tab indicate which types of results will be displayed in the Measurement List The numbers in the entry DisplayedResultT...

Page 104: ...the intervals to be applied to all cell diameter histograms note that the format should be x y z If the numbers are placed in brackets such as x y z the intervals will be shown in the histogram by def...

Page 105: ...as to which she he has been assigned Only the Administrator has the right to assign workareas see Administration of User Accounts 6 5 Changing own Password Users may change their own passwords Follow...

Page 106: ...connected to the delegation of rights is explained in the appropriate sections of this chapter Password settings can also be configured in this area 7 1 1 Creating User Accounts Before creating new u...

Page 107: ...nformation about creating functions for each pre set user role as well as editing existing functions and creating new user roles can be found under Creating and Editing User roles Follow the instructi...

Page 108: ...er can be added to one or more user groups 7 1 4 Editing and Deleting User Accounts The first name last name and username of a user account can be edited if for example an existing user is to be repla...

Page 109: ...purposes Support Support of the Cedex HiRes System by Roche technical services requires access to all operational functions similar to the Superuser role Access to the System Options should be restric...

Page 110: ...cess Only the Administrator can reverse denial of access by issuing a new password The user will be warned before the last allowed attempt Password never expires Passwords never lose their validity ex...

Page 111: ...n of measurements The user can only work with measurement data from work areas to which he has been assigned New work areas can be created and assigned to one or more users via the User Rights Managem...

Page 112: ...tem Options The Cedex HiRes Software 2 2 may need to be restarted in order for changes in the System Options to take effect All elements in the System Options that have not been explicitly described i...

Page 113: ...or the Multi Sampler DefaultCup does not influence measurements All 20 positions on the sampler plate can be used for measurements Should a sample be present in the DefaultCup position during Prime LM...

Page 114: ...can may need to be disabled since there may no longer be a sufficient amount of time for a Prescan to be taken To disable the Flow Chamber Prescan do the following 1 Open the System Options and click...

Page 115: ...e defined using this window When standard sized containers are used it is not advisable to change default settings for the Min volume and Max volume It is also possible to define a Warn Level and a Lo...

Page 116: ...tation time for all Cell Types may be 90 seconds Sedimentation time can be adjusted via the Cell Type List window as described below Individual adjustments of the operator can be helpful or necessary...

Page 117: ...5 2 The Cell Type List Window To open the Live Operator window directly from the Measurement window when it is in the View mode click on the Live Operator button located in the middle of the Measureme...

Page 118: ...g other sedimentation times Roche support will provide instructions for optimizing sedimentation times for specific cell lines 4 Make sure that the IR Operator is set to CXHiResImageOperator The IR Op...

Page 119: ...ID and Data Set of the measurement for which the image analysis should be improved The parameters for the loaded measurement are preset 6 Select an image of the measurement in the Image ID section Thi...

Page 120: ...ow and then click on the Delete button A confirmation box will appear asking the user if he she wants to delete the Cell Type If confirmed the Cell Type will be deleted and disappear from the list All...

Page 121: ...window some of the 11 parameters can be displayed on the screen at the same time Parameters at first not visible can be scrolled into view using the scroll bar under the Operator Parameter display The...

Page 122: ...er of dead cells of the current image and viability If an Operator parameter is modified the newest values will appear under New column when an automatic reprocessing of the selected image is finished...

Page 123: ...te value This parameter influences the recognition of living cells When the value of this parameter is set high contrast weak objects are also counted as living cells provided they additionally fulfil...

Page 124: ...alue is set the fewer living cells that are recognized in aggregates DCAggrApp Dead Cells Aggregate Appearance Range 10 10 Default 0 Unit Absolute value This parameter influences the recognition of de...

Page 125: ...a single measurement from the list by clicking on the field on the left of the appropriate line When choosing a set of measurements hold the Ctrl button down while selecting the appropriate lines In a...

Page 126: ...data that has been archived can be deleted from the Cedex HiRes System Database Archived data still located in the database can be searched for and displayed in the upper right hand corner of the Mea...

Page 127: ...down as a Prime can only be run when the Hardware Management is active see Scheduling Automatic Cleaning Routines Standard Clean after the final measurement of a set of samples or before a longer pau...

Page 128: ...process is automatically run after system start up or after a selectable number of measurements After certain time of inactivity A certain amount of time of inactivity can be defined after which the...

Page 129: ...nd if necessary replaced or refilled For detailed information see Refilling Containers Individually Cleaning the reagent containers when Manually Refilling All reagent containers must be thoroughly cl...

Page 130: ...ton in the Shortcuts area of the Control Center or select Cleaning routines in the Functions menu see Figure 78 Figure 78 The Cleaning window of the analyzer 3 2 1 Cleaning Options The following clean...

Page 131: ...this cleaning a solution of 0 1 1 N HCl is used instead of detergent Follow the instructions below 1 Remove the Detergent container and replace it with an appropriate container with a 0 1 1 N HCl solu...

Page 132: ...t Clean to automatically start the cleaning routine The Cedex HiRes Analyzer is blocked during the cleaning routine and the duration is continuously displayed in the Estimated Total Time field 3 2 4 I...

Page 133: ...e scan by following the instructions below 1 Place the mouse pointer anywhere on the diagram 2 Hold the left mouse button pressed down and form a box from the bottom right corner to the upper left cor...

Page 134: ...cluded in the contents of delivery If at all possible the analyzer should never be turned off If it is necessary to turn it off the analyzer needs at least 2 hours to warm up before an Automatic Adjus...

Page 135: ...ion must lie between 850 and 1250 Otherwise an authorized service technician must re adjust the Cedex HiRes Analyzer Another important value is the allowed maximum difference between the optimal focus...

Page 136: ...inge To change the syringe follow the steps specified in the sections below 5 1 Removing the Syringe Follow the instructions below 1 Click on Syringe Maintenance in the Functions menu of the Control C...

Page 137: ...do not get jammed 5 If the Syringe Maintenance window has not been opened yet select Syringe Maintenance in the Functions menu on the Control Center 6 Click on the Install button The plunger will be c...

Page 138: ...ow the instructions below 1 Remove the syringe see Removing the Syringe 2 Switch off the Cedex HiRes Analyzer 3 Lubricate the top part of the syringe guide and spindle 4 Switch on the Cedex HiRes Anal...

Page 139: ...Cedex HiRes Analyzer needs to be opened 7 Operational Data The Cedex HiRes System keeps track of some operational data including operating hours number of measurements and liquid consumption Select O...

Page 140: ...ystem Suitability Test consists of different types of SST checkpoints There are two main types of checkpoints an SST requiring inspection or maintenance activity performed by the user e g syringe chan...

Page 141: ...he offset in determines the acceptance range applicable to the results of SST measurements carried out for this checkpoint based on the target value entered Target Value Check Upper Limit Lower Limit...

Page 142: ...n the configuration in the System Options The System Options can be accessed under the Setup menu on the Control Center 1 Open the System Options and click on the General tab 2 Look for the parameter...

Page 143: ...t the SST procedure The System Suitability Test Measurement Run window will appear The parameter settings can be viewed but not altered 4 Whether or not the Target Value can be changed depends on conf...

Page 144: ...box in the middle of the System Suitability Test Run window if inspection or maintenance procedure was successful 3 Add a comment in the Comment box optional 4 Click on the Save button to confirm the...

Page 145: ...sed on date run and Reactor ID The information in the Trending list for SST with measurement window can be exported via the Export button or printed via the Print button The SST checkpoint results are...

Page 146: ...can be printed out via the Trending chart print button Figure 87 Trending Chart window There are several additional options in the Trending Chart window Excluded measurements can be removed from the c...

Page 147: ...g list for SST without measurement window see Figure 88 All of the measurements for the selected SST checkpoint are listed in this window The Trending list for SST without measurement window shows all...

Page 148: ...is only the case if the SSTFailureReaction parameter in the System Options is set on Restrict see Setting up the SSTFailureReaction in the System Options menu The Current State will be automatically...

Page 149: ...create the diagnosis file follow the instructions below 1 Click on the Setup menu on the Cedex Control Center 2 Click on Diagnosis and the Diagnosis window will appear 3 The hardware to be included i...

Page 150: ...drop down menu will appear from which level can be selected Logging is in True state by default Trace and log records are saved in files which are accessible by using Windows Explorer The records are...

Page 151: ...ar parameter i e there is a cross in the column any new value entered in the corresponding location will be automatically saved in the System Options or the User Preferences windows For example user J...

Page 152: ...ord Count 25 The number of cleanings to be used for the estimation of the average time the cleaning will take CriticalDiskSpace 1 The limit for the free memory space on the non removable disk in gigab...

Page 153: ...lear ResultListDateTime Date time when the Multi Run overall result list was cleared OverallTypeFor Exponential Regression ViableCell Density not adjustable Overall Type for the exponential regression...

Page 154: ...rmal or Medium in the case of a system version update Default precision for the measurement minimum normal superior or low medium high in the case of a system version update Measurement PrescanRequire...

Page 155: ...e Drawing Date To SampleID Measurement List Default Filter for SampleID ShowResults 0 Show result in measurement list window User Measurement List Default Filter for UserID Workarea Standard Measureme...

Page 156: ...ported CTC files DataExchange StatusReport Interval 3 Interval in seconds in which the progress bar is updated during Archive Restore Export Import ExportCertificate Innovatis AG Archive Test Certific...

Page 157: ...rkArea standard CTC Series List Default Filter for WorkArea Settings in the section CTC Views Default Filter Option Value Description Save last value CreateDateFrom CTC Views Default Filter for Measur...

Page 158: ...fore 3 Number of days in advance a user will be warned at login that a password is about to become invalid Settings in the section Reports Option Value Description Save last value ReportResultPath C C...

Page 159: ...he name of the report template for report type Operational Data ReportLanguage English Report Template Default Language Single Measurement Report Template standard The default report template for sing...

Page 160: ...oviding external XML for Measurement input output ExternalApplication Callback 0 Call external application after external measurement processing 0 False 1 True ExternalXML ExportPath C Export External...

Page 161: ...Cleaning 121 Cleaning routines 122 123 Cleaning solution 49 Clear List button 59 CMaxSize 117 CMinSize 117 Combine view 84 Compact Histogram 83 Container volume 123 Control Beads 134 Control Center 4...

Page 162: ...115 117 LM Shutdown 65 121 Location of the Analyzer 26 Locking the System 142 Lock Level 109 Log 91 Logging 144 Log In 45 Log Out 66 LogOutputPath 144 M Maintenance 121 138 Maintenance check list 121...

Page 163: ...SST edit 134 SSTFailureReaction 136 SSTLock 137 142 SST run 134 Standard Clean 121 125 Starting the Software 45 Std Dev 90 Std Size 52 Superuser 40 Switching off 65 Syringe 49 130 System functions 93...

Page 164: ...158 Cedex HiRes Analyzer Operator s Guide G G Index...

Page 165: ......

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