6. Drain/Removal Instructions
Draining can be performed in a number of configurations according to the specific application
requirements. Table 1 below gives drainage approaches according to application requirements.
Before draining the mixer, follow the following common instructions:
1. Connect the outlet port to the desired downstream equipment or receptacle.
2. Open the outlet port valve, allowing fluid to flow out of the mixer biocontainer (Figure 32).
Figure 32
Open the bayonet outlet port and any clamps on the tubing to commence draining/dispensing
3. Commence the dispensing operation, configuring the system as required according
to the table below.
Table 1
Draining regimes
Powder Port Gas
Mixer
Support
Blanket
When to Use
Comments
Off
Detached
Off
When dispensing a stable,
The mixer biocontainer will collapse during
fully mixed/dissolved
the draining process.
solution.
Draining will take approximately 40 minutes
to drain 200 L (assuming solution is drained
under gravity and not using a pump.
Pump assisted draining will be quicker).
Running
Attached
On
When maintaining
Mixer will not mix solution below 25 L.
homogeneity of a
Draining will take approximately 30 minutes.
solution during
RPM should be reduced to 100 rpm at volumes
dispensing.
less than 100 L to avoid air entrapment.
Gas blanket should be switched off as the
last of the fluid exists the mixer biocontainer.
Mixer biocontainer will not collapse during
draining/dispensing, thus appropriate venting
will be required prior to system removal.
21
USD 2743
www.pall.com/biopharm
Outlet Clamp
Outlet Port Valve
