Idexx SediVue Dx, Operator'S Manual

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18
Crystals
Crystals can come in a variety of different shapes, sizes, and
presentations. Urine pH, specific gravity, sample preparation
and handling, and drugs can all play a part in crystal formation.
Crystals in small numbers (e.g., struvites) may be normal
for some dogs but others (e.g., cystine) may signify disease
processes. The following Smart Flags are designed to provide
further clinical insight into the presence of crystalluria.
Suspect crystalluria. Review images to confirm.
When the sum of all crystal types is ≥1/HPF but no specific
crystal parameter has met the minimum threshold of 1/HPF to be reported and tagged, then the
suspect crystalluria flag will be triggered. All crystal types will still be reported as “none to rare.”
Example: STR 0.3/HPF (None to Rare, no tags)
CRY 0.75/HPF (None to Rare, no tags)
------------
1.05/HPF => Suspect crystalluria flag
Crystalline debris detected
Crystalline debris can be abundant and variable in size and
presentation in some samples. Due to background density, the
presence of large amounts of crystalline debris can affect the
identification of other formed elements in the sample.
This flag is displayed when crystalline debris has been
detected by the algorithm. The neural network algorithm has
been trained to exclude crystalline debris from the unclassified
crystal (CRY) category. When this flag is present, users will be
notified so they can be more discerning of the bacteria result
as very small particles of debris can resemble bacteria.
Urine protein:creatinine (UPC) ratio
When the Consider evaluation of urine protein:creatinine ratio message appears, the urine chemical
results indicate the presence of protein. A UPC ratio can be used to quantify protein loss in the
urine as it is unaffected by urine volume or concentration. It has been incorporated into the IRIS
Guidelines on Staging and Treatment of Chronic Kidney Disease (CKD) as an important monitoring
tool at all stages. A UPC should be performed after urinalysis with sediment examination. It is not
recommended for use if there is an “active sediment” as inflammatory conditions in the urinary tract
will increase protein and negate the usefulness of the ratio.
What if there is active sediment?
When active sediment is detected, the Recommend reevaluate proteinuria after resolution of active
sediment message appears.
First, resolve the infection. Once the sediment becomes inactive, consider running a UPC to
quantify protein loss.
Understanding Your Results