Idexx SediVue Dx, Operator'S Manual

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15
Do the images provide clinical insight?
If you are prompted to consider a dilution but you can obtain clinical insight from the images, a
dilution is unnecessary.
2
Minimal crowding Extreme crowding
No dilution required
Consider dilution:
1 part urine and 1 part saline
3
(1:2)
Dilute:
1 part urine and 4 parts saline
4
(1:5)
Dilute:
1 part urine and 9 parts saline
4
(1:10)
Slightly dense—some background
(obvious hematuria; bacteria may
be hidden)
Moderately dense—little
background
(obvious hematuria;
other formed elements may be
hidden)
Extremely dense—no background
(overlapping cells make it
impossible to discern elements
without dilution)
Image provides clinical insight
(bacteriuria and pyuria evident)
Yes No
1
Dilution flags may also result from excessive bubbles and/or fibers from dirty optics.
2
Only the first run for each sample type for the same patient in a 24-hour period will be invoiced. Multiple runs from the same patient that include one or more dilutions and do
not provide semiquantitative results will not be invoiced.
3
It may be helpful to confirm bacteria with an air-dried, stained preparation (“dry prep”), rather than a dilution.
4
Higher concentrations of diluent will affect the pH and osmolality of the sample and lead to changes in cellular appearance and the presence of crystals.
Out of focus
When the Review images to confirm results message appears, the convolutional neural network
cannot verify the quality of focus in the images. This may occur when the sample does not have
enough sediment to confirm the quality of focus or if the images are out of focus. If this message
appears in several consecutive samples with sediment present, the optical window may require
cleaning.
Bacteria
Bacteria can be a challenge to distinguish from amorphous debris and crystalline material.
When the presence of bacteria is “suspect presence,” the SediVue Dx Urine Sediment Analyzer’s
convolutional neural network will suggest that you review the patient’s images for deeper clinical
insights.
In cases where bacteria cannot be visually confirmed in the images, a dry-slide sediment cytology
(“dry prep”) may be considered to differentiate bacteria from other debris or artifacts. If bacteria are
obvious in the images, or the result is “present,” a dry prep is not necessary, but you can follow up
with a culture and sensitivity (MIC) test if you want to further classify the bacteria as well as test for
sensitivity to certain antibiotics.
Understanding Your Results