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Operating Instructions Manual

GE Xcellerex XDM Series, Operating Instructions Manual

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Action

Step

Attach the temperature probe cable to the probe support bar (for example
with a zip tie) to prevent operators from accidentally removing the temper-
ature probe from the thermowell.

4

Put the temperature probe cable into the cable holders on the short side of
the mixer vessel.

5

Xcellerex XDM 50-1000, XDUO 100-1000 mixers Operating Instructions 29251615 AD

181

6 Preparation

6.4 Prepare and install the probes

6.4.4 Insert probes into the disposable bag

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Summary of Contents for Xcellerex XDM Series

Page 1: ...Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions Original instructions Translation disc enclosed...

Page 2: ...Page intentionally left blank...

Page 3: ...ity levels 47 2 6 Recycling information 49 2 7 Declaration of Hazardous Substances DoHS 51 3 System description 52 3 1 System overview 53 3 2 Xcellerex XDM mixer system description 54 3 2 1 System har...

Page 4: ...bag assembly 147 6 3 2 Install the disposable bag 157 6 4 Prepare and install the probes 158 6 4 1 Calibrate the pH probe 163 6 4 2 Prepare the conductivity probe 165 6 4 3 Autoclave probe sheath asse...

Page 5: ...ions 279 10 2 SP CV and PV units and ranges 280 10 3 Xcellerex XDM and XDUO mixers minimum working volumes 281 10 4 Pump characteristics 282 10 5 Disposable bag specifications 283 10 6 Environmental r...

Page 6: ...Page intentionally left blank...

Page 7: ...latory information about Xcellerex XDM and XDUO mixers In this chapter See page Section 8 1 1 About this manual 9 1 2 Important user information 11 1 3 Regulatory information 17 1 4 Abbreviations Xcel...

Page 8: ...our system is described in the General Specification and on the system label Examples of jacketed and non jacketed mixer types are shown below A XDM mixer 200 L jacketed B XDUO mixer 200 L non jackete...

Page 9: ...s a stand alone instrument or as a FlexFactory component XDM and XDUO mixers are not medical devices and must not be used in any clinical procedures or for diagnostic purposes XDM and XDUO mixers are...

Page 10: ...which if not avoided could result in minor or moderate injury It is important not to pro ceed until all stated conditions are met and clearly understood NOTICE NOTICE indicates instructions that must...

Page 11: ...GE Healthcare Bio Sciences AB Name and address of manufacturer Bj rkgatan 30 SE 751 84 Uppsala Sweden In this section See page Section 12 1 3 1 EU Directives 13 1 3 2 Eurasian Customs Union 14 1 3 3...

Page 12: ...y Directive MD 2006 42 EC Electromagnetic Compatibility EMC Directive 2014 30 EU CE marking The CE marking and the corresponding EU Declaration of Conformity is valid for the in strument when it is us...

Page 13: ...ment See Manufacturing information Name and address of manufacturer Telephone 46 771 400 600 Telephone number of manufacturer GE Healthcare LLC Importer and or company for obtain ing information about...

Page 14: ...ly with the limits for a Class A digital device pursuant to part 15 of the FCC Rules These limits are designed to provide rea sonable protection against harmful interference when the equipment is oper...

Page 15: ...een evaluated for its suitability for use in a business environment When used in a residential environment there is a concern of radio interference A Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operati...

Page 16: ...nery General principles for design Risk assessment and risk reduction EN ISO 12100 Safety of Machinery Electrical equipment of machines Part 1 General requirements IEC EN 60204 1 UL 508A Industrial ca...

Page 17: ...the control signal that controls the process toward the SP programmable logic controller PLC process variable PV The actual measured value of a process parameter revolutions per minute rpm Secure Digi...

Page 18: ...read this chapter before using XDM or XDUO mixers and observe the safety instructions at all times during use In this chapter See page Section 19 2 1 Safety precautions 28 2 2 Labels 34 2 3 Emergency...

Page 19: ...understand the entire contents of this chapter to become aware of the hazards involved WARNING Operate as described Do not operate the instrument in any other way than described in the instrument user...

Page 20: ...g parts stored energy pressurization and electrical sources CAUTION Moving parts Do not place objects or fingers into valves rotating pumps fans or other moving parts This can result in damage to the...

Page 21: ...ng unpack ing transporting or moving the system wear protective footwear preferably with steel toe cap WARNING Personal protective equipment For personal safety during the transportation installation...

Page 22: ...planted heart defib rillators from getting too close to the magnets Installation WARNING Squeezing or crushing injuries Due to the significant weight of the system great care must be taken not to caus...

Page 23: ...ents is minimized CAUTION Indoor use only The product is designed for indoor use only CAUTION Slippery surface Use caution when emptying the vessel jacket and when filling the vessel jacket with the c...

Page 24: ...Tag Out LOTO WARNING High voltage The system must always be connected to a grounded power outlet System operation WARNING Ventilation Do not block the ventilation inlets or outlets on the system WARN...

Page 25: ...ION Hot surface Do not touch the vessel inner surface jacket inlet or outlet during high temperature runs The temperature of these items may be higher than 60 C CAUTION Pinch hazard Do not operate the...

Page 26: ...parts that are approved or supplied by GE may be used for maintaining or servicing the system CAUTION Hot surface Make sure that the instrument surface temperature is equal to room temperature before...

Page 27: ...ore performing any service work on the system make sure that the system has been properly decon taminated Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 27 2 Safety inst...

Page 28: ...the product Labels on the system A system label 1 with regulatory information is present on the system Your system may also have an ASME label 2 The following illustration shows the location of the la...

Page 29: ...Sciences AB 751 84 Uppsala Made in Sweden MSIP REM 2GE 0XXXX The system label information is explained below Meaning Label text Jacketed or non jacketed Vessel Type Part number of the system Code num...

Page 30: ...netic compliance EMC in Australia and New Zealand This symbol indicatesthat the product contains hazardous materials in excess of the limits established by the Chinese standard GB T 26572 Requirements...

Page 31: ...10 5 L 1 4307 304L 29241073 N B The ASME label information is explained below Meaning Label text symbol Symbol of the National Board of Boiler and Pressure Vessel Inspectors N B Registration number id...

Page 32: ...igned for FLUID Definition of fluid 1 dangerous 2 non dangerous accord ing to European legislation FLUID GROUP Vessel classification according to European legislation PED 2014 68 UE The design code us...

Page 33: ...oltage can cause se vere injury or death Turn off power and Lock Out Tag Out LOTO before service Warning Hot surface Do not touch the vessel surface and areas around the vessel jacket inlet SUPPLY and...

Page 34: ...ailure and the procedure for restarting the mixers In this section See page Section 35 2 3 1 Emergency procedures Xcellerex XDM mixer 37 2 3 2 Emergency procedures Xcellerex XDUO mixer 42 2 3 3 Power...

Page 35: ...is removed from the I O Cabinet If required disconnect the power cord from the mains power supply Restart XDM mixer Follow the instructions below to restart XDM mixer after an emergency shutdown or a...

Page 36: ...ains power supply 2 Turn the system power switch to I ON position 3 36 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 3 Emergency procedures 2 3...

Page 37: ...forced into Manual mode and remain in a safe state Agitator motor is turned off The TCU is turned off E STOP is displayed on every local control software screen Data logging continues if enabled Pres...

Page 38: ...tructions below to restart XDUO mixer after an emergency shutdown or a power failure Action Step Make sure that the condition that caused the emergency shutdown is cor rected 1 Connect the power cord...

Page 39: ...ERGENCY STOP button by turning it clockwise 4 Result The EMERGENCY STOP button pops out Tap Login on the top toolbar of the home screen 5 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructi...

Page 40: ...the text boxes Tap OK 6 Tap RESET on the local control software screen 7 40 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 2 Safety instructions 2 3 Emergency procedures...

Page 41: ...d system If a batch was running prior to when the EMERGENCY STOP was pushed the system is set in the Held state If a batch was not running XDUO mixer remains in a safe state If a batch was running pri...

Page 42: ...s described in Section 7 3 1 Start up the system on page 199 Communication failure with FlexFactory Result Event Communication between XDUO mixer and FlexFactory fails The mixer goes to local control...

Page 43: ...w the interlock limit for 30 seconds The vessel weight is more than the Max Weight interlock limit Interlocks stop the pumps pH control The vessel temperature control goes into Manual mode The pumps p...

Page 44: ...0 1000 L delay time If the interlocked PID control loop was in the Auto mode before the interlock the control restarts automatically in the Auto mode when the interlock condition is corrected and the...

Page 45: ...erlock is active The interlock icon and name are shown in orange The interlock is not active The interlock icon and name are shown in gray Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instruct...

Page 46: ...ity level System functions Administrator Supervisor Operator Monitor alarms Monitor and control pH Monitor and control the temperature Monitor the vessel weight Operate the agitators Monitor trends Co...

Page 47: ...o national and local environmental regulations Recycling of hazardous substances XDM and XDUO mixers contain hazardous substances Detailed information is available from your GE representative Disposal...

Page 48: ...upplies trans mitters pumps probes sensors etc from the I O Cabinet and the mixer vessel 2 Decontaminate the probes and sensors that have come into contact with the process fluid Dispose of the fluid...

Page 49: ...he use of such electrical and electronic products will not result in any severe environmen tal pollution any bodily injury or damage to any assets The unit of the period is Year In order to maintain t...

Page 50: ...us substance contained in all of the homogeneous materials for this part is below the limit requirement in GB T 26572 X Indicates that this hazardous substance contained in at least one of the homogen...

Page 51: ...overview 53 3 2 Xcellerex XDM mixer system description 58 3 3 Xcellerex XDUO mixer system description 63 3 4 Mixer vessel components 71 3 5 Safety hardware 72 3 6 Mixer automation and control 74 3 7 T...

Page 52: ...ngredients are added through a port at the top of the disposable bag using a hopper or a powder bag Mixing of the disposable bag contents is done by an agitator that is magnetically coupled to an impe...

Page 53: ...general overview of XDM mixer In this section See page Section 54 3 2 1 System hardware 55 3 2 2 Illustration of Xcellerex XDM mixer Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 2...

Page 54: ...n the purchased options The following monitoring functions are available Conductivity pH Temperature Weight The jacketed mixer vessel allows the temperature control of the mixer contents An ex ternal...

Page 55: ...vary according to the selected optional features Front view 4 3 2 1 10 9 8 7 6 5 Function Part Weight monitor display 1 Temperature monitor display 2 pH conductivity transmitter display 3 Xcellerex XD...

Page 56: ...ube rack 9 Probe window and probe support bar 10 Rear view 11 12 13 14 15 16 17 18 19 18 Function Part Coolant outlet to TCU 11 Mixer vessel 12 56 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating...

Page 57: ...rst disc 15 Agitator motor 16 Load cell and jacking bolt 4 17 Ventilation hood 2 18 Power switch 19 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 57 3 System descriptio...

Page 58: ...eneral overview of XDUO mixer In this section See page Section 59 3 3 1 System hardware 60 3 3 2 Illustration of Xcellerex XDUO mixer 58 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructio...

Page 59: ...thepurchasedoptions Thefollowingmonitoring functions are available Conductivity pH Temperature Weight The following control functions are available pH Temperature jacketed mixer only An external tempe...

Page 60: ...tion of each mixer may vary according to the selected optional features Front view 2 3 4 5 6 7 8 9 10 11 12 13 1 Function Part I O Cabinet 1 Base pump 2 Acid pump 3 60 Xcellerex XDM 50 1000 XDUO 100 1...

Page 61: ...touchscreen 7 Acrylic lids 8 Opening for liquid addition lines 9 Push bar 10 Side access door 11 Test tube rack 12 Probe window and probe support bar 13 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Ope...

Page 62: ...4 17 Vessel jacket safety outlet from burst disc 18 Agitator motor 19 Load cell and jacking bolt 4 20 Ventilation hood 2 21 Power switch 22 62 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Inst...

Page 63: ...of the components of the mixer vessel In this section See page Section 64 3 4 1 Mixer vessel 66 3 4 2 Agitator 68 3 4 3 Load cells 70 3 4 4 Pumps Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating I...

Page 64: ...tubing and for connecting a hopper or a powder bag See Illustration of mixer lid on page 65 A probe window is used to insert probes into the disposable bag for monitoring the contents A combined probe...

Page 65: ...1 B Function Part Opening for liquid addition lines 1 Lid part 2 Lid handle 4 3 Powder addition port1 4 1 Powder addition port is designed for connecting hopper or powder bag to the disposable bag Xce...

Page 66: ...connected Function of the agitator There are no openings in the disposable bag wall for agitation access The impeller baseplate is welded into the bottom of the disposable bag The impeller baseplate i...

Page 67: ...n 10 to 200 rpm A frequency inverter is used to change the motor speed Agitation direction The agitator can rotate clockwise or counterclockwise Description Agitator direction Fluid rotates downwards...

Page 68: ...xer vessel up lock it and take the load off from the load cells thereby preventing the damage to the load cells The jacking bolts must be disengaged during mixer operation so that the vessel weight ca...

Page 69: ...op nut 2 Lifts the vessel off the load cell Bottom nut 3 Takes the load off from the load cell Jacking bolt 4 Locks the bolt inserted into the mixer frame Bolt locking nut 5 Measures the vessel weight...

Page 70: ...luded in the configuration of XDUO mixers The pumps operate at variable speed Changing the CV between 0 and 100 increases the speed linearly over the range For the characteristics of the pumps see Sec...

Page 71: ...2 2 Labels on page 28 for detailed information Burst disc Jacketed XDM and XDUO mixers are equipped with a burst disc which is designed to rupture when the vessel jacket pressure approaches the accept...

Page 72: ...eed drive for controlling the agitator motor speed and direction The following functions are available Start and stop the agitator motor Change agitation speed Change agitation direction Xcellerex XDU...

Page 73: ...displays the cur rent process variables The modification of these variables comes into effect when the mixer is run in local mode The process variables can be modified using the local control panel F...

Page 74: ...the TCU with the mixer I O Cabinet Consult the manufacturer s manuals for more information about the TCU Models of temperature control units Two types of temperature control units can be used with th...

Page 75: ...disposable components that are needed for a mixing process In this section See page Section 76 3 8 1 Disposable bag assembly 82 3 8 2 Probe sheath assembly Xcellerex XDM 50 1000 XDUO 100 1000 mixers O...

Page 76: ...ent adjustment two probe ports and a thermowell The Plus bag assembly has one liquid addition line for acid and base solutions and the Plus Flex bag has two liquid addition lines Connection to the liq...

Page 77: ...s the top of the Plus Flex bag 1 2 7 6 5 4 3 The following illustration shows the underside of the Plus Flex bag 9 8 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 77 3...

Page 78: ...line with clamp plugged 9 1 This addition line can be used for final adjustment of liquid volume in the disposable bag 2 The line is designated for addition of acid or base solutions The following ill...

Page 79: ...e top of the Plus bag 1 2 3 4 5 6 7 8 The following illustration shows the underside of the Plus bag 1 3 4 5 6 7 8 9 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 79 3...

Page 80: ...ler baseplate with impeller assembly 9 1 This addition line can be used for final adjustment of liquid volume in the disposable bag 2 The line is designated for addition of acid and base solutions See...

Page 81: ...plugged 5 Storage of the disposable bag assembly The recommended storage temperature for the disposable bag assembly is between 10 C and 34 C Information about the storage temperature is shown on the...

Page 82: ...e ACD is used to connect the probe sheath assembly to the disposable bag The probe sheath is compatible with the following 12 225 mm probes Conductivity probe pH probe The probes are connected to the...

Page 83: ...e end 1 Aseptic membrane 2 Anti actuation ring 3 Bellows 4 End plug 5 Illustration of the probe sheath assembly The following illustration shows a probe sheath with the inserted probe Xcellerex XDM 50...

Page 84: ...tware The parts used in daily op erations are described in Section 7 3 Operate Xcellerex XDUO mixer on page 198 In this chapter See page Section 85 4 1 General description 90 4 2 Adjustment and contro...

Page 85: ...detail screen for the corresponding process variable The home screen also shows the current values of the relevant process variables Home screen The home screen is the default screen at XDUO mixer st...

Page 86: ...estart XDUO mixer on page 38 RESET 6 Nothing is shown during normal operation Shows if data logging is active The status is shown in green Logging Active or gray Logging Inactive See Start and stop da...

Page 87: ...rocess variable display The numeric fields on the process variable display show the current values of process variables Tapping the display opens the detail screen for the relevant process variable Th...

Page 88: ...ode In Auto mode the user defines a setpoint SP The local control software specifies the controlled variable CV via a PID control loop In Manual mode the user defines a controlled variable CV Batch Ti...

Page 89: ...a text box for numeric entry opens a numeric keypad The following illustration shows the numeric keypad Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 89 4 User interfa...

Page 90: ...PANEL 1 Button to open the Transmitter Offsets screen Transmitter Offsets screen on page 111 OFFSETS 2 Button to start or stop data logging The cur rent logging status is shown on the top tool bar Lo...

Page 91: ...he local control software PLC HMI SW version 10 Instrumentcontrol option FlexFactory control or local control FF Control Option 11 PROFIBUS node number applicable if the system is controlled by FlexFa...

Page 92: ...e Management screen 1 2 Description Part Text boxes for date and time information 1 Button to set the date and time 2 When the date and time are changed it may take a few minutes until the new time is...

Page 93: ...alarm overview screen and alarm configuration screens In this section See page Section 94 4 3 1 Alarm overview screen 95 4 3 2 Alarm configuration screens Xcellerex XDM 50 1000 XDUO 100 1000 mixers O...

Page 94: ...t High High Alarm The alarm icon is always gray when the alarm overview screen is open even when active alarms exist on the system Illustrationofthealarm overview screen The following illustration sho...

Page 95: ...igh Alarm High Alarm Low Alarm Low Low Alarm The alarm levels are set by the user according to process specific requirements Only Supervisor and Administrator can set the alarm limits The user opens t...

Page 96: ...not be changed by the user See Section 7 3 7 Set alarm limits on page227 for instructions how to set the accessible alarm limits See Section 2 4 Xcellerex XDUO mixer interlocks on page 43 for more inf...

Page 97: ...ll four alarm setpoints SP for each functionality If duplicate probes are installed on the system pH or temperature probes the PLC uses data from the currently selected probe for the alarm Xcellerex X...

Page 98: ...ductivity temperature and weight In this section See page Section 99 4 4 1 Overview 100 4 4 2 Agitator screen 102 4 4 3 Conductivity screen 103 4 4 4 pH screens 107 4 4 5 Temperature screens 112 4 4 6...

Page 99: ...the user back to the previous screen Tapping ALARM CONFIG opens the alarm configurationscreen for the parameter See Section 4 3 2 Alarm configuration screens on page 95 Tapping TREND opens the Trend...

Page 100: ...ed by tapping AGITATION on the navigation toolbar The following illustration shows an example of the Agitator Detail screen 1 2 3 4 5 6 7 8 100 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Ins...

Page 101: ...ate is shown as Stopped the agitator motor drive is defective 3 Agitator state indicator Running or Stopped 4 Batch Timer display 5 STOP button 6 START button 7 Toggle button to change the agitator di...

Page 102: ...navigation toolbar The following illustration shows an example of the Conductivity Detail screen The screen shows the process variable PV value for the conductivity probe 102 Xcellerex XDM 50 1000 XD...

Page 103: ...rent pH value PV displays for probes 1 and 2 The currently selected probe is shown in black AIT_121 pH PV AIT_122 pH PV 2 Two values are shown if XDUO mixer has dual pH monitoring pH controlled variab...

Page 104: ...open the Prime Pumps screen See Prime the pump on page 212 PUMPS SETUP 7 Button to open the pH PID Settings screen See pH PID Settings screen on page 105 PID SETTINGS 8 Pump speed displays controlled...

Page 105: ...rocess variable PV dis play for the selected probe PV 2 pH controlled variable CV display PID con troller output CV 3 Note In Auto mode this value is calculated by the PLC In Manual mode Manual CV is...

Page 106: ...ortional 7 I Term integral D Term derivative Pump speed displays controlled variable CV for the acid pump and the base pump Shown in of total pump speed range SC_201 Acid PID CV SC_202 Base PID CV 8 1...

Page 107: ...Text box for input TC_163 Temperature SP 1 Current temperature process variable PV displays for temperature probe sensors 1 and 2 The currently selected sensor is shown in black TE_161 Temperature PV...

Page 108: ...open the Transmitter Offsets screen See Transmitter Offsets screen on page 111 OFFSETS 5 Button to open the Temperature PID screen See Temperature PID screen on page 109 PID SETTINGS 6 Toggle button t...

Page 109: ...e process variable PV display for currently selected temperature sensor PV 2 Note The sensor is selected on the Temperature Detail screen Temperature PID controller output controlled variable CV displ...

Page 110: ...rding to the actual operating range of the TCU CV HiLimit CV LoLimit 6 User defined limits for the input range of temperature setpoint SP of disposable bag contents Note The SP limits specify the allo...

Page 111: ...reen The currently selected sensor is shown in black The following illustration shows an example of the Transmitter Offsets screen 1 2 3 Function Description Part Displays of the actual process variab...

Page 112: ...the Weight Detail screen The screen shows the process variable PV value for the mixer vessel weight Tapping Tare lets the user to tare the mixer vessel weight See Section 7 3 6 Manage mixer weight on...

Page 113: ...r the setpoint SP and the current process variable PV The Conductivity Trend and Weight Trend screens show only the graph for the current process variable PV Trending is displayed for the last 5 minut...

Page 114: ...t applicable Weight XDUO 1001 250 kg Not applicable Not applicable Weight XDUO 2001 625 kg Not applicable Not applicable Weight XDUO 5001 1250 kg Not applicable Not applicable Weight XDUO10001 1 Negat...

Page 115: ...s variable PV axis and measurement unit 1 Graph area 2 Controlled variable CV axis and measurement unit 3 Legend 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 115 4 U...

Page 116: ...not covered in this manual must not be installed by the customer For unpacking instructions see separate Xcellerex XDM and XDUO mixers Unpacking Instructions manual In this chapter See page Section 11...

Page 117: ...impeller assembly of the disposable bags OBSERVE and follow instructions for installation operation and maintenance of XDM and XDUO mixer KEEP a safe distance of 25 cm or more from the magnets to avo...

Page 118: ...ocedure for Lock Out Tag Out LOTO WARNING Keep jacking bolts Do not remove jacking bolts from the installed system CAUTION Tripping hazard Make sure that all tubing hoses and cables are placed so that...

Page 119: ...nt working conditions during the use sufficient space should be provided on all sides of the instrument when installed at the intended production location Environmental conditions The following genera...

Page 120: ...ch must be set in the O OFF position and the power cord must be disconnected Computer An external computer is not required Temperature regulation For temperature control of the jacketed XDM mixer or X...

Page 121: ...rsonnel only WARNING High voltage The system must always be connected to a grounded power outlet The customer must install an electrical plug on the main power cord of XDM and XDUO mixers The plug mus...

Page 122: ...ribed in the user documentation If you do you may be exposed to hazards that can lead to personal injury and you may cause damage to the equipment Connect TCU Follow the instructions below to connect...

Page 123: ...surface Use caution when emptying the vessel jacket and when filling the vessel jacket with the coolant Spilling the coolant on the floor makes the floor slippery and may cause acci dents For informa...

Page 124: ...t with the coolant Action Step Make sure that the vent valve and the drain valve of the mixer vessel jacket are closed 1 124 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615...

Page 125: ...ant inlet SUPPLY of the mixer vessel 2 Connect the TCU inlet tubing to the coolant outlet RETURN of the mixer vessel 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 125...

Page 126: ...h both parts of the connector together c Release the locking ring Result The locking ring moves back and emits a click The connector is locked Remove the reservoir cap on the TCU and and fill the rese...

Page 127: ...emptying the vessel jacket and when filling the vessel jacket with the coolant Spilling the coolant on the floor makes the floor slippery and may cause acci dents Follow the instructions below to empt...

Page 128: ...e content of the tubing into the vessel jacket 7 Prepare the tubing for draining the vessel jacket bottom 8 a Attach a Snap tite connector to the tubing b Put the end of the drain tubing into the coll...

Page 129: ...pter See page Section 130 6 1 Safety precautions 132 6 2 Stabilize the mixer vessel 139 6 3 Prepare the disposable bag 157 6 4 Prepare and install the probes 182 6 5 Calibrate the monitors of Xcellere...

Page 130: ...DEATH or SERIOUS INJURY Magnets are located on the bottom of XDM and XDUO mixer and in the impeller assembly of the disposable bags OBSERVE and follow instructions for installation operation and maint...

Page 131: ...engage the jacking bolts before moving the instrument This prevents damage to the load cells Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 131 6 Preparation 6 1 Safety...

Page 132: ...at XDM and XDUO mixers are in a stable position during preparation and operation In this section See page Section 133 6 2 1 Use jacking bolts 138 6 2 2 Lock and unlock casters 132 Xcellerex XDM 50 100...

Page 133: ...The jacking bolt threads are undamaged The jacking bolts are fully engaged in the mixer vessel frame The top and bottom nuts turn freely using fingers alone Turn up the bottom nut 1 with your fingers...

Page 134: ...nut and tighten it slightly with a wrench 4 Repeat steps 2 to 4 for all four jacking bolts installed on the mixer 5 Result The jacking bolts are engaged and the load cells are protected from possible...

Page 135: ...o disengage the jacking bolts Action Step Turn up the securing nut 1 on the bolt by a few turns using a wrench 1 1 2 Turn up the top nut 2 on the bolt by 1 to 2 turns using the wrench 2 Xcellerex XDM...

Page 136: ...nut must be at least 2 to 3 mm 3 Repeat steps 1 to 3 for all four jacking bolts installed on the mixer 4 Result The jacking bolts are disengaged The load cells support the mixer vessel 136 Xcellerex X...

Page 137: ...ions Depending on site require ments a functional check or load cell calibration might be required before operating the mixer Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615...

Page 138: ...by pressing down the tab on each brake Unlock the casters Before moving the instrument unlock each caster by pushing hard the top tab towards the instrument frame 138 Xcellerex XDM 50 1000 XDUO 100 10...

Page 139: ...assembly The in structions are applicable for both XDM and XDUO mixers In this section See page Section 140 6 3 1 Unpack the disposable bag assembly 147 6 3 2 Install the disposable bag Xcellerex XDM...

Page 140: ...bag size 60 60 cm 25 25 in 100 L 70 70 cm 30 30 in 200 L 90 90 cm 40 40 in 500 L 110 110 cm 45 45 in 1000 L To unpack a 200 L or larger bag assembly you need an assistant to help you Start unpacking t...

Page 141: ...sembly and place the bag on the inspection table 2 Carefully open the outer protective bag and take out the bag assembly 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD...

Page 142: ...the wrap from the tubing ports tubing connectors and filters These items need protection during bag installation The wrap can be removed after the bag has been installed 142 Xcellerex XDM 50 1000 XDU...

Page 143: ...ade in USA GE Healthcare Bio Sciences Corp 14 Walkup Drive Westborough MA 01581 Patents www pall com patents DESCRIPTION 1 2 Note The label above is an example Actual data printed on the label is spec...

Page 144: ...remove the protective bags from the probe ports tubing connectors and filters Unprotected connectors may be damaged or contaminated during the installation of the disposable bag Remove the protection...

Page 145: ...es that hold the lines together Loose lines can be damaged during bag installation Remove the bubble wrap from the drain line 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 292516...

Page 146: ...failed bag integrity 5 Verify that the clamps on all lines are closed 6 Carefully turn over the bag assembly and remove the bubble wrap and foam from the impeller baseplate 7 Remove any additional wra...

Page 147: ...isposable bag installation wipe clean and dry the vessel wall if necessary Water on the vessel wall might be mistaken for bag leakage Follow the instructions below to start the installation of the bag...

Page 148: ...ow the instruc tions below 2 a Hold the door handle tightly b Turn the door counterclockwise c Remove the door 148 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Prepa...

Page 149: ...om center 1 Drain opening at the bottom corner of the vessel 2 Probe window at the side corner of the vessel 3 Side access opening if applicable 1 2 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operat...

Page 150: ...the vessel 3 If you are installing a Plus or Plus Flex bag assembly make sure that the probe connectors 1 face the probe port 2 1 2 150 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instruction...

Page 151: ...pull the line through the opening Tip The drain line is more easily reached from the underside of the vessel 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 151 6 Prepa...

Page 152: ...wly lower the impeller baseplate onto the agitator drive head 6 Result The impeller baseplate connects magnetically to the drive head A click is heard when the contact is made Note Verify visually tha...

Page 153: ...does not function correctly If the agitator emits a loud clicking noise during operation the impeller baseplate is decoupled from the magnetic drive head To correct the impeller position follow the in...

Page 154: ...lation on page 147 3 Complete bag installation If you are installing a Plus or Plus Flex bag assembly insert the pH and conductivity probes into the disposable bag See Section 6 4 Prepare and install...

Page 155: ...ect position of tubing helps the adjustment of the disposable bag Install the hopper if applicable A Disconnect the TC clamp from the disposable bag powder addition port 2 Xcellerex XDM 50 1000 XDUO 1...

Page 156: ...powder addition port C Put the hopper onto the powder addition port and secure it with the TC clamp 156 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 6 Preparation 6 3...

Page 157: ...for the Plus and Plus Flex bag assembly In this section See page Section 158 6 4 1 Calibrate the pH probe 163 6 4 2 Prepare the conductivity probe 165 6 4 3 Autoclave probe sheath assembly 168 6 4 4...

Page 158: ...the pH probe as follows Action Step Take a pH probe out of the packaging 1 Rinse the sensor end of the pH probe with de ionized water 2 Connect the pH probe with the probe cable so that no thread is...

Page 159: ...display on the I O Cabinet Press MENU 1 1 1 2 3 Result A menu is displayed on the transmitter screen Use the navigation keys to make selections in the menu 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixer...

Page 160: ...probe at pH 10 as follows 4 1 Put the probe in the pH 10 buffer Stir approximately ten times and make sure no air bubbles are present on the probe 2 Press ENTER to start the calibration When the calib...

Page 161: ...g has been completed before pH probe standardization The disposable bag has been filled The contents of the disposable bag have been equilibrated to the process tempera ture The temperature probe has...

Page 162: ...ct Sensor 1 and press ENTER 3 Select pH and press ENTER 4 Select Standardize and press ENTER 5 Enter the externally measured pH value of your sample and press ENTER 6 Press EXIT 3 repeatedly until you...

Page 163: ...de ionized water 2 Connect the conductivity probe with the probe cable so that no thread is visible on the probe 3 NOTICE Do not cross thread the probe cable Find the cell constant value in the accom...

Page 164: ...he main screen is displayed The conductivity probe is ready to be used Rinse the probe with de ionized water 7 Disconnect the probe cable from the probe 8 This procedure is sufficient for most applica...

Page 165: ...ratchet clamps Prepare for autoclaving Before autoclaving the probe sheath assembly prepare the following Disposable pipette Deionized water Follow the instructions below to prepare the probe sheath...

Page 166: ...team inside the probe sheath assembly during autoclaving 4 Remove the pipette 5 Verify that the O rings are present on the probe 6 Insert the probe into the probe sheath assembly through the threaded...

Page 167: ...mbly is ready to be placed in the autoclave Place the probe sheath assembly into the autoclave The paper membrane end of the probe sheath assembly 1 should be lower than the plug end of the assembly T...

Page 168: ...bag NOTICE Ratchet clamps may break if they are overtightened A ratchet clamp can be released from its tightened state by sliding the interlocked clamp fingers sideways with respect to each other If r...

Page 169: ...llowing illustration 1 Using your fingers loosely tighten the ratchet clamps until the teeth on the clamp are engaged enough to hold the clamp in position 2 to 3 teeth en gaged 2 NOTICE Do not tighten...

Page 170: ...ion 2 to 3 teeth en gaged 4 NOTICE Do not tighten the clamps too much otherwise they prevent the insertion of the probe into the disposable bag Install probe sheath assembly Before inserting the probe...

Page 171: ...ectors 3 Hold the male ACD connector on the probe sheath assembly and align it with the female connector on the probe port on the disposable bag so that the white membrane strips are facing each other...

Page 172: ...odies of both connectors with one hand grip both white membrane strips with the other hand and pull them perpendicular to the connectors simultaneously away from the bodies of the connectors in one sm...

Page 173: ...ssembly on the short section of silicone tubing between the dispos able bag and the female ACD connector Remove the anti actuation ring which prevents unintentional engagement before the ACD connector...

Page 174: ...nnector until the thumb rest meets the body 8 Note A ratchet sound is heard from the male ACD connector during this motion 174 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 2925161...

Page 175: ...dication that the connection might not be aseptic immediately clamp off this probe sheath assembly on the short section of silicone tubing be tween the disposable bag and the female ACD connec tor Xce...

Page 176: ...he disposable bag compressing the bellows section of the probe sheath assembly 10 Result The bellows section is fully compressed as shown below 176 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating...

Page 177: ...wn that even if a ratchet clamp breaks the probe itself would not be damaged even if it is a pH probe with a glass body Result The tip of the probe extends above the surface at the inside of the dispo...

Page 178: ...12 Collect all loose probe cables and place the cables into the cable holders on the short side of the mixer vessel 13 Clamp off any unused probe port connections 14 178 Xcellerex XDM 50 1000 XDUO 10...

Page 179: ...No additional measures are needed to prevent the probe from sliding out of the disposable bag Install the temperature probe Follow the instructions below to install the temperature probe into the disp...

Page 180: ...The connectors and labels on your instrument may differ from the configura tion shown below 2 Carefully insert the temperature probe into the thermowell 3 180 Xcellerex XDM 50 1000 XDUO 100 1000 mixe...

Page 181: ...ntally removing the temper ature probe from the thermowell 4 Put the temperature probe cable into the cable holders on the short side of the mixer vessel 5 Xcellerex XDM 50 1000 XDUO 100 1000 mixers O...

Page 182: ...l allow monitoring of disposable bag temperature and vessel weight To calibrate the monitors see the instructions in the monitor manufacturer s documen tation 182 Xcellerex XDM 50 1000 XDUO 100 1000 m...

Page 183: ...to the disposable bag See Illustrations of the Plus Flex bag assembly on page 77 for overview of the disposable bag The following table explains the pump labels Specification Label Addition of acid so...

Page 184: ...of the liquid flow through the pump when the pump is running in a clockwise direction See the following section for tubing installation instructions 184 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Oper...

Page 185: ...tubing in pump model 313 follow the instructions below Action Step Open the pump head cover 1 Insert the tubing through the pump 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 292...

Page 186: ...a turn clockwise 4 CAUTION Do not overtighten Do not overtightenthe adjustment wheel on the pumps The flow through the tubing may be cut off Calibrate the pump XDUO mixer pumps are not calibrated 186...

Page 187: ...r gives instructions for the operation of both mixers In this chapter See page Section 188 7 1 Safety precautions 190 7 2 Operate Xcellerex XDM mixer 198 7 3 Operate Xcellerex XDUO mixer 229 7 4 Add l...

Page 188: ...st comply with the national code of practice for biosafety WARNING Clamps on pump tubing Make sure the tubing between the pump and the disposable bag is not blocked or clamped WARNING Slipping hazard...

Page 189: ...ON Secure pump tubing Make sure that the pump tubing is secure and in good condition before using the pump Do not block or kink the tubing downstream of the pump Xcellerex XDM 50 1000 XDUO 100 1000 mi...

Page 190: ...is section See page Section 191 7 2 1 Start up the system 192 7 2 2 Operate the agitator motor 196 7 2 3 Monitor temperature and weight 197 7 2 4 Monitor pH and conductivity 190 Xcellerex XDM 50 1000...

Page 191: ...the system To start the XDM mixer turn the system power switch to I ON position Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 191 7 Operation 7 2 Operate Xcellerex XDM...

Page 192: ...t the minimum working volume This prevents bag damage The minimum working volume depends on the mixer vessel size See Section 10 3 Xcellerex XDM and XDUO mixers minimum working volumes on page 280 for...

Page 193: ...efore starting the agitator motor and during the run Follow the instructions below to adjust the agitator run conditions Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 1...

Page 194: ...h the up and down arrow buttons 1 Result The digital display shows the motor speed 194 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 7 Operation 7 2 Operate Xcellerex X...

Page 195: ...digital display F Forward the agitator rotates in clockwise direction R Reverse the agitator rotates in counterclockwise direction See Agitation direction on page 67 for more information Xcellerex XDM...

Page 196: ...nitoring starts automatically Monitor weight of the disposable bag The lower display shows the mixer weight When the power to the XDM mixer is turned on the weight monitoring starts automatically To t...

Page 197: ...parameters The transmitter display shows the measured pH and conductivity mS cm values Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 197 7 Operation 7 2 Operate Xceller...

Page 198: ...page Section 199 7 3 1 Start up the system 207 7 3 2 Operate the agitator motor 211 7 3 3 Prepare the pump 215 7 3 4 Control the pH 220 7 3 5 Control the temperature 225 7 3 6 Manage mixer weight 227...

Page 199: ...XDUO mixer Action Step Make sure that the EMERGENCY STOP button is disengaged 1 Turn the system power switch to I ON position 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251...

Page 200: ...ype your user name and password in the text boxes Tap OK 2 Result The user is logged in The Login text changes and shows the current user name Note The current user name is shown on all local control...

Page 201: ...on the top toolbar 3 Result The local control of the mixer is enabled Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 201 7 Operation 7 3 Operate Xcellerex XDUO mixer 7...

Page 202: ...low the instructions below to connect the XDUO mixer to FlexFactory Action Step Log in to local control software as described in Log in on page 200 1 Log in to FlexFactory software as described in Fle...

Page 203: ...en 3 Result XDUO Mixer System Info screen is shown Tap Request FlexFactory Control 4 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 203 7 Operation 7 3 Operate Xcellerex...

Page 204: ...l Disconnect from Xcellerex FlexFactory Follow the instructions below to disconnect from FlexFactory Action Step Tap INFO on the home screen 1 Result XDUO Mixer System Info screen is shown 204 Xceller...

Page 205: ...a logging saves the data to the memory card on the HMI The data can then be transferred manually to a USB memory stick using the USB port or directly to an external computer using the Ethernet port Fo...

Page 206: ...tive message 2 changes to green Logging Active message To stop logging tap STOP LOGGING 2 Result Data logging stops The STOP LOGGING button text changes to START LOGGING The green Logging Active messa...

Page 207: ...n Follow the instructions below to start and control the agitator motor Action Step On the home screen make sure that the Min Weight and Max Weight inter locks are not active 1 The inactive interlocks...

Page 208: ...e agitator in viscous solutions may cause the agitator blade to decouple A clicking or knocking sound is heard if this happens Decreasing agitator speed helps to prevent the agitator blade from decoup...

Page 209: ...e home screen tap Agitation to open the Agitator Detail screen 1 On the Agitator Detail screen tap STOP 2 Result The agitator motor stops Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructi...

Page 210: ...direction Follow the instructions below to change the agitation direction Action Step On the home screen tap Agitation to open the Agitator Detail screen 1 On the Agitator Detail screen drag the toggl...

Page 211: ...nstructions below to change the pump direction Action Step On the home screen tap pH to open the pH Detail screen 1 On the pH Detail screen tap PUMPS SETUP 2 Result The Prime Pumps screen opens Xcelle...

Page 212: ...direction through the pump Tap BACK to return to the pH Detail screen 4 Prime the pump Follow the instructions below to prime the pump Action Step Make sure the pH probes are installed in the disposa...

Page 213: ...n on the home screen is a valid value 2 On the home screen tap pH top open the pH Detail screen 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 213 7 Operation 7 3 Oper...

Page 214: ...pump press and hold Base 5 Result The pump rotates at the 35 of maximum speed CV 35 while the button is pressed Release the button when the pump is primed 6 Tap BACK to return to the pH Detail screen...

Page 215: ...to work in Auto or in Manual mode In Auto mode the PLC controls the pH of the disposable bag contents to the setpoint SP In Manual mode the PLC keeps the pump speed at the manually defined CV value of...

Page 216: ...tton to AIT121 or AIT122 to select the applicable pH probe 2 Type an applicable pH setpoint value into the PHC_125 pH SP text box 3 216 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instruction...

Page 217: ...efined CV pHC_125 Manual CV range 0 to 50 controls the CV of the acid pump SC_201 and the CV range 50 to 100 controls the base pump SC_202 See the table below SC_202 Base CV SC_201 Acid CV pHC_125 Man...

Page 218: ...follow the instructions below Action Step On the home screen tap pH to open the pH Detail screen 1 Set the mixer in Manual mode drag the toggle button to Manual 2 218 Xcellerex XDM 50 1000 XDUO 100 10...

Page 219: ...ove into the PHC_125 Manual CV text box 3 Result The instrument keeps the pump speed as specified using a split range control loop Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 292...

Page 220: ...y defined CV value to the TCU In both modes the TCU calculates a fixed setpoint SP using the configured range that is specific for the TCU model Work in Auto mode To set the temperature control to wor...

Page 221: ...the active temperature sensor is a valid value 2 Tap TEMP on the home screen to open the Temperature Detail screen 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 221...

Page 222: ...icable temperature setpoint value into the TC_163 Temperature SP text box 2 5 Set the mixer in Auto mode drag the toggle button to Auto 6 Result The control of mixer vessel temperature is enabled 222...

Page 223: ...home screen make sure that no interlocks are active The inactive interlocks are shown in gray 1 Tap TEMP on the home screen to open the Temperature Detail screen 2 Xcellerex XDM 50 1000 XDUO 100 1000...

Page 224: ...le value of total TCU remote setpoint range into the TC_163 Manual CV text box 2 4 Result The control of mixer vessel temperature is enabled 224 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating In...

Page 225: ...lock Follow the instructions below to tare the mixer vessel weight Action Step Make sure that the disposable bag is empty before starting the tare proce dure The mixer vessel jacket can be filled with...

Page 226: ...red The Tare Confirmation screen stays open Verify that the WT_176 Weight PV value is reset to approximately 0 kg 5 Tap BACK 2 to close the Tare Confirmation screen 6 On the Weight Detail screen tap H...

Page 227: ...screen for each functionality Only Supervisor and Administrator can set the alarm limits Follow the instructions below to set or change the alarm limits Action Step On the navigation toolbar tap the b...

Page 228: ...etpoint text boxes 1 3 1 2 Result The alarm limits are set Tap BACK 2 to go back to the Detail screen 4 On the Detail screen tap BACK to go back to the home screen 5 228 Xcellerex XDM 50 1000 XDUO 100...

Page 229: ...ds are added through the addition lines The illustration below shows the possible liquid entry points 1 2 Function Part Main addition line Use this line for filling the disposable bag 1 Liquid additio...

Page 230: ...he drain line is fully engaged 3 Remove the side access door from 500 and 1000 L mixers Follow the instruc tions below 4 a Hold the door handle tightly b Turn the door counterclockwise c Remove the do...

Page 231: ...g through the liquid addition line i d 1 Stop filling when the liquid level has reached 3 to 5 cm and the bag begins to adjust to the shape of the mixer vessel 2 Verify that the following conditions a...

Page 232: ...d level rises above the lowest edge of the side access opening Finish the addition of liquids To finish the addition of liquids follow the instructions below Action Step Continue filling the disposabl...

Page 233: ...ixer has a weight monitoring option monitor the weight of the added liquid on the local control software home screen XDUO mixer or on the weight monitor display XDM mixer Decrease the filling speed wh...

Page 234: ...the powder addition port in place 6 For 50 to 500 L mixers push the powder addition port of the bag into the center opening of the lid 7 Push another lid section in place while keeping the powder add...

Page 235: ...nserted into the opening as shown in the following illustration 9 Adjust the lines through the rectangular lid openings 10 If needed clamp the fill lines and disconnect the liquid source 11 Xcellerex...

Page 236: ...end of the liquid addition process if possible Add solid material slowly to avoid supersaturated solutions in the mixer Consider using a hoist when lifting large containers with solid material Add so...

Page 237: ...500 L mixers push the powder addition port of the bag into the center opening of the lid 2 Push another lid section in place while keeping the powder addition port in the opening Keep the TC clamp ab...

Page 238: ...own in the following illustration 4 Disconnect the TC clamp from the powder addition port 5 Remove the protective cap from the powder addition port 6 Make sure that the O ring stays in place on the po...

Page 239: ...agitator motor 9 Add the solids to the bag contents through the hopper 10 When the addition is complete remove the hopper Tip Push the vessel lid section outwards for easier access to the powder addi...

Page 240: ...ation is applicable for both XDM and XDUO mixers In this section See page Section 241 7 6 1 Collect the product 242 7 6 2 Remove the disposable bag 247 7 6 3 Shut down the system 240 Xcellerex XDM 50...

Page 241: ...e the mixer vessel lid 2 Open the clamp on the drain line 3 Monitor the draining process to make sure that it continues as expected 4 Gently adjust the disposable bag position during the draining proc...

Page 242: ...sure the disposable bag is empty 1 Verify that the agitator motor is not running See Start and stop the agitator motor on page 192 or Stop the agitator motor on page 209 for instructions how to stop...

Page 243: ...a clean place according to manufacturer s instruction 5 Remove the pH and conductivity probes from the disposable bag Clean the probes according to facility procedures Autoclave and store the probes i...

Page 244: ...ling magnetic components There is a strong magnetic attraction between the impeller and the motor drive coupling Follow the instructions below to remove the disposable bag from the mixer vessel 244 Xc...

Page 245: ...Remove the door Disconnect the agitator drive head by pulling off the impeller baseplate of the disposable bag from the magnetic drive head in the agitator opening 2 Lift the disposable bag out of th...

Page 246: ...mination of the bag prior to disposal rinse the walls of the empty bag with a bleach solution then drain 1 Dispose of the bag assembly according to national and local environmental regulations 2 246 X...

Page 247: ...xer do the following Action Step Turn the system power switch to O OFF position 1 If required disconnect the power cord 2 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD...

Page 248: ...In this chapter See page Section 249 8 1 Safety precautions 250 8 2 Maintenance schedules 253 8 3 Lock Out Tag Out LOTO turn off procedure 255 8 4 Lock Out Tag Out LOTO turn on procedure 257 8 5 Clea...

Page 249: ...trical equipment before doing maintenance CAUTION Contamination hazard Before performing any service work on the system make sure that the system has been properly decon taminated NOTICE Always engage...

Page 250: ...reas must be clean and free of any hazardous contaminants before a Service Engineer starts maintenance work Please complete the checklist in the On Site Service Health and Safety Declaration Form or t...

Page 251: ...person nel Inspect cables and con nectors Annuallyandafter system relocation Inspect hinges and han dles Inspect jacking bolts on page 259 Properly trained person nel Inspect jacking bolts If anythin...

Page 252: ...calibration Beforeeachbatch Section 10 8 Temperature probe calibration on page 289 Calibration technician Temperature probe cali bration Semi annually or as needed See the manufacturer s manual GE se...

Page 253: ...tage It is essential for the safety of personnel working in or around electrically powered equipment to follow a company policy and procedure for Lock Out Tag Out LOTO Turn off the instrument Follow t...

Page 254: ...For a jacketed mixer empty the mixer vessel jacket as described in Empty the vessel jacket on page 127 4 For a jacketed mixer attach a tag out device onto the mixer vessel coolant inlet 5 254 Xceller...

Page 255: ...policy and procedure for Lock Out Tag Out LOTO Turn on the instrument Follow the instructions below to turn on XDM mixer or XDUO mixer Action Step For a jacketed mixer if your mixer should be connecte...

Page 256: ...Action Step Turn the system power switch to I ON position 4 256 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 8 Maintenance 8 4 Lock Out Tag Out LOTO turn on procedure...

Page 257: ...ver immerse any part of the equipment in liquid or spray liquid on the equipment Always make sure that the equipment is com pletely dry before plugging it in Always follow all environmental health and...

Page 258: ...or of the mixer vessel and the I O Cabinet 2 Check all stainless steel components for signs of surface rust If rust is found do as follows 3 1 Scrub areas of surface rust with an extra fine mildly abr...

Page 259: ...h and safety standards and practices as estab lished within the country where the equipment is installed Local provincial bylaws must be followed The owner of the instrument is responsible that releva...

Page 260: ...emove the ruptured burst disc 3 Insert the new burst disc See the manufacturer s documentation for more information 4 Attach the clamp 5 Close the clamp with the screw 6 260 Xcellerex XDM 50 1000 XDUO...

Page 261: ...he mixer weight See Tare mixer weight on page 225 for instructions 2 Use water or weights to increase the mixer weight 3 Add a known quantity of water into the disposable bag installed inside the mixe...

Page 262: ...to the added weight 4 Result Mixer weight monitoring functionality is verified Note If the weight reading is not correct contact your GE representative for assis tance 262 Xcellerex XDM 50 1000 XDUO...

Page 263: ...on Contact your GE representative for instructions on how to store move and re install the instrument Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 263 8 Maintenance 8...

Page 264: ...ts contact GE for service The motor is overloaded Variable frequency drive VFD is not functioning as expected Connect the power cable Power cable is not connected Contact your GE representative to rep...

Page 265: ...E STOP Enable the agitator See FlexFactory Automation User Manual for more information The agitator is not enabled The agitator does not start on FlexFactory controlled mixer Tap RESET on the local c...

Page 266: ...Corrective action Possible causes Problem Connect the power cable Power cable is not connected The local control panel does not function Contact your GE representative for replacement cable The main p...

Page 267: ...is empty Prime the pumps The pumps are not primed Free the feed line Feed line before or after the pump is kinked Free the feed line Feed line before or after the pump is clamped Conduct a study to ve...

Page 268: ...ith isopropyl or methyl alcohol to remove the water from beneath the con tacts Note Do not immerse the plug ends in liquid Use an aerosol spray to introduce the alcohol pH or conductivity connector wa...

Page 269: ...or right All tubing used in the pumps will wear out with use over time The tubing is worn out Use only tubing rated for use in peri staltic pump head Verify that the cause of the E STOP condition is...

Page 270: ...is yes the connection is working properly 4 If the display message is no the connection is not functioning Check the connection cable be tween the TCU and PLC Check if the connection between the I O C...

Page 271: ...part ment to perform a cornering test and determine which load cell has failed Load cell has failed physically or electrically broken Verify that the mixer vessel legs are free of any obstructions or...

Page 272: ...weight is within the operationalrange Verify that the mixer vessel legs are free of any obstructions or blocking objects Physical obstruction of load cell motion Disengage the jacking bolt See Diseng...

Page 273: ...System specifications 279 10 2 SP CV and PV units and ranges 280 10 3 Xcellerex XDM and XDUO mixers minimum working volumes 281 10 4 Pump characteristics 282 10 5 Disposable bag specifications 283 10...

Page 274: ...DM 50 Dimensions W H D 970 1090 870 mm 38 43 34 in XDM 100 1100 1120 1000 mm 43 44 39 in XDM 200 1300 1480 1200 mm 51 58 47 in XDM 500 1500 1590 1410 mm 59 62 55 in XDM 1000 100 kg 220 lb XDM 50 Weigh...

Page 275: ...struction material Polycarbonate Lid Stainless steel nylon polyurethane Casters 70 dB A XDM 50 to 1000 Sound level Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 275 10...

Page 276: ...70 mm 39 44 30 in XDM 200 1190 1480 970 mm 46 58 38 in XDM 500 1390 1590 1180 mm 54 62 46 in XDM 1000 85 kg 190 lb XDM 50 Weight 100 kg 220 lb XDM 100 125 kg 280 lb XDM 200 185 kg 410 lb XDM 500 295 k...

Page 277: ...XDUO 200 1350 1480 1200 mm 53 58 47 in XDUO 500 1550 1590 1410 mm 61 62 55 in XDUO 1000 155 kg 340 lb XDUO 100 Weight 200 kg 440 lb XDUO 200 315 kg 690 lb XDUO 500 440 kg 970 lb XDUO 1000 3 8 L XDUO 1...

Page 278: ...4 30 in XDUO 200 1240 1480 970 mm 48 58 38 in XDUO 500 1440 1590 1180 mm 56 62 46 in XDUO 1000 115 kg 250 lb XDUO 100 Weight 140 kg 310 lb XDUO 200 200 kg 440 lb XDUO 500 310 kg 680 lb XDUO 1000 Stain...

Page 279: ...itator speed 0 to 150 mS cm Not applicable Not applicable Conductivity 0 to 14 0 to 100 0 to 14 pH Not applicable 0 to 100 Not applicable Pumps 0 C to 100 C 0 to 75 0 C to 60 C Vessel temperature The...

Page 280: ...s Minimum working volume L Mixer vessel size 17 50 L 28 100 L 44 200 L 76 500 L 119 1000 L 280 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10...

Page 281: ...peed Low speed Tubing i d Maximal flow rate Maximal speed Maximal flow rate Maximal speed 0 35 L min 350 rpm 0 1 L min 100 rpm 3 2 mm 1 75 L min 350 rpm 0 5 L min 100 rpm 8 mm Xcellerex XDM 50 1000 XD...

Page 282: ...mbly is between 10 C and 34 C Information about the storage temperature is shown on the bag label Operating temperature The disposable bag assembly is rated for temperatures between 5 C and 65 C 282 X...

Page 283: ...wed location 5 C to 30 C Ambient temperature operation 20 to 85 RH non condensing Max relative humidity operation 20 C to 60 C Ambient temperature transportation 20 C to 50 C Ambient temperature stora...

Page 284: ...specifications for TCU In this section See page Section 285 10 7 1 TCU requirements 287 10 7 2 Temperature control optimization 288 10 7 3 TCU coolant specifications 284 Xcellerex XDM 50 1000 XDUO 10...

Page 285: ...DUO mixers only Required On Off emergency stop TCU requirements 500 L 1000 L mixer Value Parameter Property 9 kW Cooling capacity 500 L mixer General requirements 15 kW Cooling capacity 1000 L mixer 9...

Page 286: ...int Remote control interface for XDUO mixers only Required On Off emergency stop 286 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Reference information 10 7 Tempera...

Page 287: ...s weight or if a different TCU is used the vessel temperature control can be optimized for these conditions The PID parameter values shown in the table below are given as starting points for further o...

Page 288: ...7 8 pH None CO2 aggressive 0 3 mg L Iron 0 05 mg L Manganese 250 mg L Sulfate 250 mg L Chloride 40 mg L COD 1000 CFU mL Bacteria TCU coolant composition The use of corrosion inhibitor in the coolant...

Page 289: ...ur instrument configuration Both sensors have to be calibrated simultane ously Note Preparation Before you start to calibrate the temperature probe prepare the following Temperature calibration instru...

Page 290: ...Make sure that the temperature probe is inserted into the liquid by at least 7 5 cm Note Do not wet the probe connector 3 Wait until the system reaches the equilibrium 4 Record the data for both the...

Page 291: ...ent If the temperature probe is out of tolerance follow the steps below to adjust the probe Action Step Using the data obtained during the calibration procedure calculate the offset to adjust the prob...

Page 292: ...mperature Detail screen On the Temperature Detail screen tap OFFSETS Result The Transmitter Offsets screen opens 292 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD 10 Re...

Page 293: ...the operating temperature does not bring the system into tolerance replace the temperature probe and repeat the calibration procedure If the calibration of the new temperature probe does not bring th...

Page 294: ...ions Literature Service Training Ordering information Contact information Contact information can be found on the back page of this document For more advanced technical information contact the manufac...

Page 295: ...blesurvey Adequate space andclearance is providedto allowsafe access forinstrumentservice repairor installation Insome cases this mayrequirecustomerto move equipmentfrom normaloperatinglocation prior...

Page 296: ...logical substances pleasespecify OtherHazardous Chemicals please specify Equipment must be decontaminatedpriortoservice return Pleaseprovide atelephone number whereGE cancontact youfor additionalinfor...

Page 297: ...ollowing this information section the following appendices are found in this manual Appendix B Add and remove users on page 298 Appendix C Download audit and data logs on page 304 Appendix D Privacy a...

Page 298: ...lable to Administrator Manage the Administrator account The factory settings for Administrator account in XDUO mixer local control software are as follows User ID Administrator Password admin It is re...

Page 299: ...o open the XDUO Mixer System Info screen 2 Tap USER ADMIN on the XDUO Mixer System Info screen to open the User Administration screen 3 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instruction...

Page 300: ...ox 4 Type the new password in the text box and tap Return 5 Result The password dialog box re opens Close the dialog box by tapping the close button 6 Result The new administrator password is saved an...

Page 301: ...se the dialog box by tapping the close button 5 Result The new password is saved and hidden Tap the new user row in the Group column 3 to open the group list 6 In the group list tap the applicable gro...

Page 302: ...the new information in the dialog box and tap Return 3 Result The new entry is recorded in the software The user cannot log in with previous name or password anymore Tap the user row in the Group col...

Page 303: ...lete the user name and tap Return 2 Result The user account is deleted NOTICE Do not delete the HMIAdmin account This account is used by GE service personnel Xcellerex XDM 50 1000 XDUO 100 1000 mixers...

Page 304: ...finition Term Abbreviation 0 to 100 Pump 1 speed SC201_Acid_PID_Out put 0 to 100 Pump 2 speed SC202_Base_PID_Out put Not applicable pH AIT121_PH1_PV Not applicable pH1 AIT122_1_PH2_PV millisiemens per...

Page 305: ...derside of the I O Cabinet 1 Open a web browser on the computer 2 Type 172 20 42 152 into the web browser address bar 1 and tap Enter 3 Result The HMI Miniweb start screen opens 1 2 Click the Login li...

Page 306: ...Step Click File Browser in the left pane 5 Click Storage Card SD in the File Browser pane 6 306 Xcellerex XDM 50 1000 XDUO 100 1000 mixers Operating Instructions 29251615 AD C Download audit and data...

Page 307: ...data verify that the computer region and language settings in Control Panel are set to English United States This makes sure that your time data format is compatible with Excel Tip Download the logs...

Page 308: ...tion about administrator account 2 Tap INFO on the home screen to open the XDUO Mixer System Info screen 3 Tap CONTROL PANEL on the XDUO Mixer System Info screen to open the Windows CE Control Panel...

Page 309: ...menu click Paste 9 Remove the USB memory stick from the connection port and install the protective cover 10 If you want to create a graph using your exported time data verify that the computer region...

Page 310: ...nagement of cyber security threats GE recommends to implement cyber secure operation as part of an overall defence in depth information assurance strategy that is used throughout an Information Techno...

Page 311: ...r should use an effective arrangement for isolating and protecting the network for example implementing firewall protection demilitarized zones DMZs virtual Local Area Networks VLANs and network encla...

Page 312: ...f this Appendix Cyber security vulnerability GE works closely with the third party software suppliers to monitor and evaluate cyber security vulnerabilities applicable to this product This work includ...

Page 313: ...troubleshooting 265 Agitator blade slipping 208 Agitator Detail screen 100 Agitator speed measuring units 279 Alarm Critical Alarm 96 set limits 227 Alarm configuration screen 95 illustration 97 Alar...

Page 314: ...2 Data export 304 Data logging start or stop 205 Data logs download 304 Data storage cyber security 312 Deadband 267 Delete user account 302 Dimensions 274 276 278 Disconnect FlexFactory 204 lines 242...

Page 315: ...232 Installation 116 Interlocks 43 220 223 Agitator 43 high weight 43 local control software 44 Max Weight 43 Min Weight 43 status 44 J Jacket emptying 127 filling 124 volume 123 Jacketed mixer 54 sy...

Page 316: ...loop 215 troubleshooting 267 268 pH control Auto mode 215 Manual mode 217 split range loop 215 pH Detail screen 103 pH PID Settings screen 105 pH probe calibration 158 illustration 82 insert into prob...

Page 317: ...ion 252 maintenance 251 Screens Agitator Detail 100 alarm configuration 95 alarm overview 94 Conductivity Detail 102 home screen 85 pH Detail 103 pH PID Settings 105 Temperature Detail 107 Temperature...

Page 318: ...nctioning 271 Transmitter Offsets screen 111 Transport unpacked 121 Trending ranges 114 Trend screen 113 Troubleshooting 264 agitation XDM mixer 264 burst disc 266 conductivity 268 load cells 271 loca...

Page 319: ...illustration 55 monitor weight 196 operation 190 pH 197 restart 35 start 191 start agitator 192 stop agitator 192 tare weight 196 temperature 196 XDUO mixer agitator direction 210 control 72 emergency...

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Page 322: ...operty of their respective owners 2017 2018 General Electric Company All goods and services are sold subject to the terms and conditions of sale of the company within GE Healthcare which supplies them...

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