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4 Operation
4.4 Scaling up
24
FineLINE 35
oligo
column
Operating Instructions
28-9649-57
AA
4.4 Scaling up
When scaling up to the full scale process, there are several practical issues to consider
such as pressure limitations of related large scale equipment and the special aspects of
liquid handling and process control at high volumetric flow rates.
Linear flow rates and the number of column volumes used during method development
should generally be the same as those to be used during the envisaged full scale
process.
Summary of Contents for FineLINE 35 oligo
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Page 4: ...Table of Contents 4 FineLINE 35 oligo column Operating Instructions 28 9649 57 AA ...
Page 18: ...3 Installation 18 FineLINE 35 oligo column Operating Instructions 28 9649 57 AA ...
Page 34: ...6 Troubleshooting 34 FineLINE 35 oligo column Operating Instructions 28 9649 57 AA ...
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