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Operating the 280-DS

280-DS Operator’s Manual

RPM Detection Magnetic Clip Placement

If applicable, place the magnetic clip in the appropriate position as illustrated
by the software.

If the dissolution apparatus is offline, you will be prompted to start the spindle
rotation with an appropriate speed. Otherwise, rotation will begin
automatically.

Figure 40.

RPM Detection Magnet Placement

Click

Run

to continue to the next screen and start the test.

Summary of Contents for 280-DS

Page 1: ...280 DS G7980AA Mechanical Qualification System Operator s Manual ...

Page 2: ...th these terms the warranty terms in the separate agreement shall control Technology Licenses The hardware and or software described in this document are furnished under a licenseand may be usedor copiedonly in accordance with the terms of such license Restricted Rights Legend U S Government Restricted Rights Software and technical data rights granted to the federal government include only those r...

Page 3: ...e 14 Magnetic Clip 15 Temperature Probe 15 Setting up the 280 DS 16 Cable Connections 16 Power Cord Connections 16 Requirements and Configuration 18 Environmental Requirements for Use 18 PC Requirements 18 Software Installation 19 Upgrading 280 DS Workstation 19 Migrating 280 DS Data to different PC 20 Local Security Policy 21 Starting 280 DS Workstation 23 Starting 280 DS Workstation 23 280 DS Wo...

Page 4: ...47 Diagnostics 78 Test Reports 82 Trends 85 Security 21 CFR Part 11 Compliance 87 Change User 87 Lock Application 87 Audit Trail 88 Permissions 89 Tools 90 Database Backup and Restore Functions 93 5 Troubleshooting and Maintenance 95 Preventive Maintenance 96 Recalibration 96 Troubleshooting 97 6 Service and Warranty 101 Service and Warranty Information 102 Obtaining Warranty and Other Services 10...

Page 5: ...280 DS Operator s Manual 5 1 Safety Notes Cautions and Warnings 6 ...

Page 6: ...recautions could result in death or injury Read all warnings and cautions carefully and observe them at all times Caution CAUTION A Caution message appears in the manual when failure to observe instructions could result in damage to equipment Agilent supplied and or other associated equipment Note NOTE A Note appears in the manual to give advice or information ...

Page 7: ...not be disposed of as unsorted municipal waste All Agilent products that are subject to the WEEE directive shipped after August 13 2005 are compliant with the WEEE marking requirements Such products are marked with the crossed out wheelie bin WEEE symbol in accordance with European Standard EN 50419 For more information on collection reuse and recycling systems please contact your local regional w...

Page 8: ...1 Safety 8 280 DS Operator s Manual This page was intentionally left blank except for this message ...

Page 9: ...280 DS Operator s Manual 9 2 Introduction ...

Page 10: ... on a 1 liter dissolution apparatus vessel plate level and vibration bath or vessel temperatures paddle or basket height spindle shaft centering spindle shaft verticality spindle shaft wobble spindle shaft speed RPM vessel verticality and basket rim wobble The software interface which is designed to run on Microsoft Windows 7 or 10 32 bit and 64 bit implements controls for the Electronic Records a...

Page 11: ...280 DS Operator s Manual 11 3 Setting Up the 280 DS Unpacking Your Equipment 12 280 DS Components 13 Setting up the 280 DS 16 Requirements and Configuration 18 Starting 280 DS Workstation 23 ...

Page 12: ... Module IM with a USB cable The IM connects to the Vessel Module VM through the module intercommunication cable The VM is inserted into the vessel for all position specific measurements The IM is placed on an applicable flat surface e g the vessel plate and provides the temperature probe interface Prior to use 1 Remove all system components from the packing material 2 Inspect the equipment and acc...

Page 13: ... The Vessel Module VM measures rotational speed basket shaft wobble vessel centering shaft verticality vessel verticality and basket paddle height Once properly positioned this module provides reliable repeatable measurements using innovative sensing technology Figure 1 Vessel Module ...

Page 14: ... is used to record vessel plate level x and y axis and vibration x y and z axis while also acting as a hub for the Vessel Module temperature probe and connection to the PC Quantitative values for each parameter are recorded and visible in real time via the software interface Figure 2 Instrument Module ...

Page 15: ...RPM Each time the magnet passes the sensor one rotation is counted Figure 3 Magnetic Clip Temperature Probe The temperature probe is used to verify the accuracy of the water bath and vessel temperature probes on the dissolution apparatus It can also be used to record individual temperatures prior to beginning a dissolution test Figure 4 Temperature Probe ...

Page 16: ...een the power receptacle on the PC and an AC electrical supply of the appropriate voltage If using a laptop the 280 DS can also be used when the laptop is on battery power NOTE The online testing mode provides direct communication between the dissolution apparatus and the 280 DS Workstation software This feature is only available for Agilent Varian or VanKel dissolution apparatus models For PCs wi...

Page 17: ...S Operator s Manual 17 2 Connect or verify connection of the AC power cord between the power receptacle on the dissolution apparatus and an AC electrical supply of the appropriate voltage 3 Turn on the PC and dissolution apparatus ...

Page 18: ...g Indoor use only Temperature 10 ºC to 35 ºC PC Requirements The software is designed to run on a PC based platform with the following minimum specifications 1 5 GHz or faster Pentium 4 processor 1 GB of RAM or more 16X CD ROM drive 1 USB port minimum 10 GB of space on the hard drive 1280 x 960 at 16M colors minimum Windows 7 or 10 32 bit or 64 bit operating system ...

Page 19: ...instructions on screen Post upgrade Cleanup Steps Optional 1 Go to Control Panel Programs Programs and Features 2 Select Microsoft SQL Server 2005 and click Uninstall Follow the on screen instructions to remove this program NOTE You must log on to the computer as an administrator to set up the software and run it for the first time NOTE If Windows User Access Control UAC displays during the instal...

Page 20: ... DS Workstation and follow the instructions on screen 4 After upgrading 280 DS Workstation on the old computer go to Programs Agilent Dissolution MSDE Manager to create another backup of this database 5 Transfer this database backup file bak to the new computer e g via USB stick 6 On the new computer go to Programs Agilent Dissolution MSDE Manager to restore the database NOTE To move 280 DS Workst...

Page 21: ...OTE For 21 CFR Part 11 compliance purposes physical requirement section 11 300 b you must ensure that the following minimum requirements are met by your system s security policy Internal IT requirements may differ from the settings outlines in this section It may be necessary to coordinate this configuration with the domain controller Policy Security Setting Enforce Password History 3 passwords re...

Page 22: ...ies Audit Policy and set the options Policy Security Setting Account lockout duration 0 minutes infinite Account lockout threshold 3 invalid login attempts Reset account lockout counter 99999 minutes Policy Security Setting Audit account logon events Success Failure Audit account management Success Failure Audit login events Success Failure Audit policy change Success Failure ...

Page 23: ...le click the 280 DS Workstation icon on the Windows desktop to start the software 2 If your system has Windows Firewall enabled the Windows Security Alert screen displays Click Unblock to enable the program NOTE You must log on to the computer as an administrator to set up the software and run it for the first time ...

Page 24: ...Up the 280 DS 24 280 DS Operator s Manual 280 DS Workstation Logon Figure 5 Logon 1 From the logon screen enter your credentials in the User ID and Password boxes 2 Click OK 3 Click Logon to initiate the software ...

Page 25: ... on the Configuration Dialog screen Click User Administration at the bottom of the screen The Local Users and Groups screen displays Figure 6 Local Users and Groups 3 Double click the Groups folder to expand the list of groups 4 Double click all eight of the groups that begin with Vk and ensure that your username is logged in and is identified as a member of these groups NOTE To complete this sect...

Page 26: ...lect Users Computers Services Accounts or Groups screen displays Figure 7 Adding a User 6 Enter your user identification in the empty box and click Check Names Ensure your user identification and domain populate the empty field Click OK 7 Close the Local Users and Groups screen 8 Click OK to close the Configuration Dialog screen ...

Page 27: ...280 DS Operator s Manual 27 4 Operating the 280 DS 280 DS Workstation Logon 28 280 DS Operation 30 Security 21 CFR Part 11 Compliance 87 ...

Page 28: ...ick 280 DS Workstation icon The Logon screen displays Figure 8 Logon 2 Enter your Windows credentials in the User ID and Password boxes 3 Verify the domain and the dissolution server are correct and click Logon The 280 DS Workstation screen displays Figure 9 280 DS Workstation Homescreen ...

Page 29: ...41 Diagnostics Verify communication or view real time data from the modules See Diagnostics on page 78 Test Reports Search and retrieve previously executed tests based on various filtered criteria See Test Reports on page 82 Trends Create custom reports showing performance over time for a particular dissolution apparatus operator or date range See Trends on page 85 Change User Log on to the 280 DS...

Page 30: ...report for the selected dissolution apparatus Properties Displays the current settings for the selected dissolution apparatus Recover Deleted Allows you to recover deleted dissolution apparatus which can be selected from a list of deleted items Show Audit Trail Displays a list of all revisions toa specific dissolutionapparatuswith theability to compare multiple versions and view the differences No...

Page 31: ...te to enter a new instrument or simply double click an existing apparatus file to open the Configuration Editor and edit its current conditions NOTE If an Agilent dissolution apparatus is connected to the computer you can import its serial number and identification information by clicking Download ...

Page 32: ...ratus ID Any internal identification associated with the apparatus Location Location of the dissolution apparatus Vessels Number of vessels between 1 and 14 Temperature Probes Specify temperature measuring devices bath and or vessel Vessel Numbering Available vessel numbering schema numbering options Edit Custom Schema If Custom Schema is selected from the drop down options you can click here to s...

Page 33: ...solution Apparatus Shaft Diameters Option Function Default Shaft Diameter Enter the value manually and press Fill with default to fill the fields with the entered value You can also enter each shaft diameter individually Shaft Measurement Device Enter the model serial number and calibration information associated with the measurement device e g caliper used ...

Page 34: ...1 8 Component Select a Part Type from the drop down list Basket Shaft Basket Paddle Shaft Receptor Shaft Vessel Serial Number Enter the serial number for the associated part Manufacturer Enter the manufacturer of the accessory or select from the available options of the drop down list Certificate Click to upload and link a certificate of conformance to the specified accessory This file may be a pd...

Page 35: ...hen upon completion of the wizard you will be asked to explain or provide a reason for the change to comply with 21 CFR Part 11 Figure 14 Reason for Change NOTE You can click Cancel at any time and no changes will be saved You can also click Finish at any time to skip remaining steps ...

Page 36: ...80 DS Workstation homescreen click Method Editor to access the Test Methods screen Figure 15 Test Methods 1 If an existing method is displayed in the list double click the entry to open the Method Editor When editing a method previously saved information displays in the fields ...

Page 37: ...ary of a particular method version Properties Opens the selected method for editing Recover Recovers deleted methods from the database Show Audit Trail Displays a list of all of the revisions of the method This allows you to compare two versions of a method and view the differences between them Note To create a report detailing version changes highlight the desired versions by clicking and holding...

Page 38: ...Failed Measurements When this option is enabled you will be required to enter a comment when a value is acquired outside of the parameter specifications Update Qualification Record When this option is selected upon successful completion of the method the dissolution apparatus qualification date is reset to the current date and you are prompted to schedule the next due date An instrument log is mai...

Page 39: ...ng the values If any adjustment is made to the pre loaded specifications Custom will display as the Compliance Specification Place a check in the n a box to exclude that test from the method Figure 17 Specification Tab 3 You can click OK or Cancel on any page of this sequence If you have changed the method you will be asked for a reason for the change After you enter a reason for the change the me...

Page 40: ...4 Operating the 280 DS 40 280 DS Operator s Manual instead Figure 18 Reason for Change NOTE You can click the Cancel at any time and no changes will be saved ...

Page 41: ... DS Workstation homescreen click Run Method to run a method Select Test Method The illustration in the figure below depicts the connection between the 280 DS modules and the PC 1 Ensure the 280 DS IM and VM cables are connected 2 Click Next to open the connection Figure 19 Select Test Method ...

Page 42: ...solution apparatus or offline testing 1 Select Online Testing or leave it unchecked 2 Click Next to continue NOTE If Online Testing is enabled the software will search for an available dissolution apparatus If this option is left disabled you will be prompted to select the Dissolution Apparatus from the list of existing configurations Online Testing is only available with Agilent and supported Var...

Page 43: ...ing the 280 DS 280 DS Operator s Manual 43 Selecting the Dissolution Apparatus 1 Select the dissolution apparatus to be measured if applicable 2 Click Next to continue Figure 21 Select the Dissolution Apparatus ...

Page 44: ...ng the 280 DS 44 280 DS Operator s Manual Selecting Test Method The screen displays a list of available methods 1 Select the method to be executed 2 Click Next to continue Figure 22 Select the 280 DS Test Method ...

Page 45: ...2 Click Next to continue Figure 23 Stirring Element and Vessel Positions NOTE If any of the Active Positions are unchecked the software will notify you that the dissolution apparatus qualification record will not be updated since no positions are being tested For any test procedure executed with less than the complete set of active vessels FOR REFERENCE ONLY will appear on the final test report ...

Page 46: ...mary and Dissolution Assembly Summary 1 Review and or print a report of the method and dissolution apparatus The Method tab is displayed by default 2 When finished click Begin Test to begin testing Figure 24 Method Summary Tab Figure 25 Dissolution Apparatus Tab ...

Page 47: ... created You can check the activity log at any time by clicking the Activity Log tab You can also print the activity log before exiting the method if Print Activity Log is enabled NOTE When you click Begin Test the software will guide you through the sequence of tests defined within the method See Method Editor on page 36 ...

Page 48: ...he 280 DS Instrument Module IM on the vessel plate as shown in the figure below 1 Position the IM on the vessel plate in an appropriate location 2 Click Run to start data collection Figure 26 IM Position on Vessel Plate NOTE The AS FOUND values displayed on the lower left of the screen will be recorded on the test report when you click Run This data is updated in real time ...

Page 49: ...ssel plate if it is not level A green check mark displays on the screen if an acceptable level has been verified 2 Click Accept to record the result Figure 27 Vessel Plate Level Measurement NOTE If you select Require Comments on Failed Measurements when setting up a method you will be required to enter a comment with an explanation for any failed result ...

Page 50: ... Zero to continue the test CAUTION Ensure the manifold and evaporation covers on the dissolution apparatus are removed prior to using the Vessel Module Refer to the applicable section in the documentation of your dissolution apparatus for removal instructions CAUTION Do not place a finger in the cavity in the bottom of the Vessel Module Doing so can contaminate the lenses inside and cause invalid ...

Page 51: ...4 Operating the 280 DS 280 DS Operator s Manual 51 Figure 28 Proper Hand Position to Zero Diameter Arm Figure 29 VM Vessel Centering Arm Placement ...

Page 52: ...4 Operating the 280 DS 52 280 DS Operator s Manual Vessel Module Placement Figure 30 Position for Vessel Module Placement ...

Page 53: ...dule into the dissolution vessel and position it as illustrated by the software Ensure that the height arm extension reaches the bottom middle of the dissolution vessel Figure 31 Diameter Measurement Arm Lever CAUTION The diameter measurement arm should be either retracted or held manually during the insertion process ...

Page 54: ...al NOTE You may need to adjust the height arm of the Vessel Module to allow for the extension to reach the bottom center of the dissolution vessel To adjust the travel of this arm adjust the pin setting as shown in Figure 32 Figure 32 Height Arm Pin ...

Page 55: ...to the vessel so it is oriented with the vessel diameter arm going into the DDM cutout on the EaseAlign centering ring Once lowered turn the Vessel Module so that the arm lever doesn t contact the EaseAlign ring posts NOTE For 7025 and 7030 models evaporation covers must be removed prior to VM insertion For 708 DS 709 DS 7000 and 7010 models it is necessary to remove the sampling manifold and evap...

Page 56: ...he Vessel 4 Lower the paddle or basket to the operating position 5 Check the AS FOUND values to ensure the shaft has been detected and the VM is properly seated The AS FOUND values are displayed to ensure proper placement The AS FOUND values will be stored and displayed on the final report when you select Run 6 Click Run to move on to the first in vessel test WARNING The Vessel Module contains sev...

Page 57: ...ept button is available for selection and release it The maximum reading is recorded as basket paddle height Figure 35 Paddle or Basket Height 3 Click Accept to store the value and continue to the next screen NOTE If a basket or paddle is not at the desired position you can adjust and re measure it by clicking Reset to repeat the test Ensure that the Vessel Module height arm extension is touching ...

Page 58: ...4 Operating the 280 DS 58 280 DS Operator s Manual Figure 36 Paddle Basket Height ...

Page 59: ...actory results have been achieved you can document the Vessel Orientation in the open text field The description you enter will be displayed on the report and stored for future reference 2 Click Accept to continue to the next screen NOTE You can make adjustments to the dissolution apparatus at any time prior to clicking Accept to optimize the performance of the instrument NOTE Comments entered und...

Page 60: ...iate position as illustrated by the software Click the desired radio button to specify 20 or 50 RPM 2 Click Run to continue to the next screen where the test begins NOTE If the dissolution apparatus is used in Offline Mode the prompt page instructs you to start the spindle rotation at the predefined speed NOTE If the dissolution apparatus is offline then the rotation has to be manually initiated b...

Page 61: ...he shaft wobble test measures wobble above the paddle blade or basket over a stability period while the spindles rotate with a predefined speed of 20 or 50 RPM Figure 39 Shaft Wobble Measurement 1 Once the value stabilizes click Accept to store it and continue to the next screen ...

Page 62: ...ip in the appropriate position as illustrated by the software 2 If the dissolution apparatus is offline you will be prompted to start the spindle rotation with an appropriate speed Otherwise rotation will begin automatically Figure 40 RPM Detection Magnet Placement 3 Click Run to continue to the next screen and start the test ...

Page 63: ... 63 RPM Measurement The Rotational Speed Test measures actual RPM against the target RPM over a stability period until the value sufficiently stabilizes Figure 41 RPM Measurement 1 Click Accept to store the RPM value and continue to the next screen ...

Page 64: ...asket at the level of the basket wobble sensor as illustrated by the software If the dissolution apparatus is offline it is necessary to manually initiate spindle rotation at the pre selected speed of 20 or 50 RPM Figure 42 Basket Placement for Rim Wobble Test 2 Click Run to continue to the next screen and start the test ...

Page 65: ...nual 65 Basket Wobble Measurement The Basket Wobble test measures the runout at the lower rim of the basket over a stability period while the spindles rotate at the specified RPM 1 Click Run to start this test Figure 43 Basket Wobble Measurement ...

Page 66: ...s Manual Figure 44 Basket Rim Wobble Measurement 2 Click Accept to continue to the next screen NOTE The steps previously described for VM measurements are repeated for each position specified during the method setup See Method Editor on page 36 ...

Page 67: ...ossible to raise the paddle or basket out of the vessel Figure 45 Paddle Basket Raise 2 Click Next to continue to the next vessel position if applicable CAUTION If paddles are installed it is necessary to orient the paddle blade so it fits through the opening of the 280 DS VM prior to raising the dissolution apparatus or shaft ...

Page 68: ...cal Qualification for the Position 1 Raise the drive unit as instructed by the software Figure 46 Completion of the Mechanical Qualification 2 The Mechanical Qualification for the individual vessel position is complete Click Next to continue to next action of the test sequence ...

Page 69: ...prompted to set the temperature to the target value If the dissolution apparatus is in the Online Mode the temperature will be set automatically Figure 47 Temperature Probe Placement 2 Click Run to continue to the next screen and run the test NOTE Heating the water bath can be a lengthy process so it is recommended to preheat the bath prior to beginning the measurement sequence ...

Page 70: ...u must enter the bath temperature as reported on its display Although a successful test requires reaching the target temperature you can accept the result at anytime Figure 48 Bath Temperature Measurement 2 After 30 seconds the reading stabilizes Click Accept to continue to the next screen NOTE If applicable do not remove the bath temperature probe of the dissolution apparatus from the water bath ...

Page 71: ...mpted to wait until the temperature of the water in the vessel reaches the target value If the dissolution apparatus is online the temperature will be detected automatically Figure 49 Vessel Temperature Probe Placement 2 Click Run to continue to the next screen and start the test NOTE Since heating is a lengthy process it is recommended to preheat the water bath before using the 280 DS ...

Page 72: ...ssel temperature reading of the dissolution apparatus if it is online 1 If the dissolution apparatus is offline enter the vessel temperature as it is displayed on its front panel or elsewhere Although a successful test requires the target temperature to be reached you can accept the result at any time Figure 50 Vessel Temperature Measurement 2 Click Accept to continue to the next page ...

Page 73: ...ll be the last test in the sequence 1 The 280 DS Test tab is selected by default Use the check boxes to specify the desired RPMs for the vibration test Figure 51 IM Placement for Vibration Test 2 Click Run to continue to the next screen If more than one RPM has been selected the software will proceed through each test individually ...

Page 74: ...ration Display 1 Click Accept to store the vibration values and continue to the next screen The software will continue to guide you through all selected RPMs Option Function X Axis Vibration Measures and displays vibration recorded on X axis Y Axis Vibration Measures and displays vibration recorded on Y axis Z Axis Vibration Measures and displays vibration recorded on Z axis Resultant Calculates a...

Page 75: ...date If any of the tests failed then the dissolution apparatus is marked Out of Calibration and the old calibration due date cannot be updated If Update Qualification Record is not selected then the old qualification due date remains and will be displayed for reference only Figure 53 Test Completion Screen Successful 2 Click Complete to update the physical parameters and display the Method Complet...

Page 76: ...4 Operating the 280 DS 76 280 DS Operator s Manual Figure 54 Test Completion Screen Unsuccessful ...

Page 77: ...the method any time by clicking Cancel Before exiting the method run you will be required to provide an explanation or reason for the cancellation Figure 55 Method Cancelling NOTE Until the first test and its results are accepted you may cancel the test without providing an explanation ...

Page 78: ...tics Current Status Tab Click Diagnostics from the 280 DS homescreen to access software diagnostics When you select Diagnostics the software automatically connects to the 280 DS if it is present and live data streams are initiated Figure 56 Current Status Tab ...

Page 79: ...p the stream of data change the rate of collection switch between full precision no calibrated data values applied and raw data normal operation modes You can also send zeroing commands and turn on off the auxiliary LEDs for basket wobble measurement Any of the streaming values can be plotted on the running chart by clicking on grid value All the communication with 280 DS can be monitored saved an...

Page 80: ...ws you to stop and restart the vibration data in order to take a snapshot of the data Figure 58 Vibration Tab The vibration data can be recorded and replayed When you click and select the output file the accelerometer data is saved as the tab delimited three column spreadsheet Each column represents acceleration on the X Y and Z axis To stop the recording click and to see the recorded data click N...

Page 81: ...o 20 previous calibration records Figure 59 Module Information Tab If an Agilent dissolution apparatus is connected to the same PC it can be controlled from the software through the dialog box When you click from the Advanced or Vibration tab the software automatically tries to connect to the dissolution apparatus If the dissolution apparatus connection is successful you are able to set up a tempe...

Page 82: ...escreen to set up and access reports Various filtering criteria is available to display the desired test reports stored in the database Report Selection Date range inclusive apparatus serial number for operator laboratory Due date all dissolution apparatus Date range and 280 DS module serial numbers Test ID Status ...

Page 83: ...esults reports can be displayed based on date range dissolution apparatus serial number 280 DS module operator laboratory due date report status test ID and test status by selecting the applicable option and clicking Filter Print Search List Creates a printable version of the report selection list which is visible on screen ...

Page 84: ...compliance Mechanical Qualification Report Sheet and detailed report Figure 61 Show Result Option Function Sign Select to electronically sign the report You will have to enter your User ID and Password to sign the report Verify Executes data verification Options Select Options to select which options will display Show Report Sheet Show Detailed Report Show Run Log ...

Page 85: ...Verify Report Integrity option at the top of the screen prompts the software to check the checksum of the results data to verify that it was not altered from outside of the application See Verify Integrity on page 30 Trends When you select Trends from the 280 DS Workstation homescreen a menu displays that allows you to define which trend graphs to plot Trend graphs are plotted per dissolution appa...

Page 86: ...4 Operating the 280 DS 86 280 DS Operator s Manual For each test the overall trending and per position trending is displayed Figure 63 MQ Measurements Trends ...

Page 87: ... account logged in to the software click Change User from the 280 DS Workstation homescreen 2 Enter login information and click Logon Lock Application 1 To lock the application click Lock Application from the 280 DS Workstation homescreen 2 To unlock click the lock icon and log back into the software Figure 64 Lock Application ...

Page 88: ...tation homescreen to access the Security Audit Trail screen Figure 65 Security Audit Trail Option Function Show Report Creates a detailed report of Security Audit Trail activity based on the date range specified Retrieve Records Allows for record retrieval of the specified Security Audit Trail activity ...

Page 89: ...4 Operating the 280 DS 280 DS Operator s Manual 89 Permissions Review the permissions granted to the current user Figure 66 Permissions ...

Page 90: ...s Options from the 280 DS Workstation homescreen to display the Configuration Dialog screens Figure 67 Configuration Dialog Security Tab Option Function User Groups Review the permissions granted to each user group User Administration Modify the permissions granted to each user and or group ...

Page 91: ...erver Name of the dissolution server where the database is located Integrated Security Allows you to assume responsibility for administrating database access Change DB Settings Updates the current settings of the database NOTE Database backup and restore functions can be performed manually Database Backup and Restore Functions on page 93 or automatically using scripts provided by Agilent If this u...

Page 92: ...s Tab Option Function Use Simulated Instruments Runs the software in a simulation mode where the 280 DS modules do not have to be connected No official data is acquired in this mode Idle Minutes Amount of time before the software locks automatically Setting this value to 0 disables this feature ...

Page 93: ... 2 Select the appropriate Server where the database is located and click Connect The DB Utility screen displays indicating the database is connected successfully 3 From the Backup tab click to browse for the desired backup location The default location is C Program Files Microsoft SQL Server MSSQL DISSO Backup DissoWkStn bak 4 Click Backup to initiate the database backup process A DissoWkStn bak f...

Page 94: ...MSDE Manager screen displays Figure 71 MSDE Manager 2 Select the appropriate Server where the database is located and click Connect The DB Utility screen displays indicating the database has connected successfully 3 Click the Restore tab and click to browse for the desired backup file bak 4 Click Restore to restore the database to the specified destination ...

Page 95: ...280 DS Operator s Manual 95 5 Troubleshooting and Maintenance Preventive Maintenance 96 Troubleshooting 97 ...

Page 96: ...ation period please refer to the following information The unit is designed to be stored transported and shipped in its original carrying case As with any delicate instrument or calibrated device excessive shipping or mishandling may warrant more frequent recalibration Ultimately the end user is responsible for establishing a calibration interval and Agilent will accommodate more or less frequent ...

Page 97: ...Ensure the USB cable is plugged in Ensure the IM cable is plugged in Look inside the VM and confirm that the red LEDs are flashing The 280 DS driver is not installed properly In Windows Device Manager verify that the 280 DS is located on a COM port when it is plugged into a USB port Ensure the USB port on the computer is functioning Diagnostics is not working properly Problem with Windows OS or VM...

Page 98: ...ion The top of the RPM clip needs to be slightly above the VM See RPM Detection Magnetic Clip Placement on page 62 Paddle Basket height is not reading properly Height arm extension not seated on bottom middle of the dissolution vessel Need to select the proper pin height Ensure that the height arm extension is oriented in the center of the VM Ensure the proper pin setting of the VM is selected See...

Page 99: ...ration Tools Options See Adding Users to the Application on page 25 User cannot log on to software Incorrect password or domain Verify the correct password has been entered and the proper domain is selected from the software login screen Data not updating in real time or SIMULATED is displayed as the serial number of dissolution apparatus Use Simulated Instruments option enabled Disable the Use Si...

Page 100: ...5 Troubleshooting and Maintenance 100 280 DS Operator s Manual This page was intentionally left blank except for this message ...

Page 101: ...280 DS Operator s Manual 101 6 Service and Warranty Service and Warranty Information 102 ...

Page 102: ... of its authorized representatives Obtaining Warranty and Other Services To place a service order warranty or other services please contact your local Customer Care Center Contact information can be found at www agilent com under your country using the Contact Us link Place your service request using the displayed phone number or E mail address ...

Page 103: ...nologies Inc 2019 70 9071 Rev D May 2019 In This Book Chapter 1 Safety Chapter 2 Introduction Chapter 3 Setting Up the 280 DS Chapter 4 Operating the 280 DS Chapter 5 Maintenance and Troubleshooting Chapter 6 Service and Warranty ...

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