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PANNORAMIC® DESK DW II 3.0.4 

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December 8, 2021 

 Rev.1 

Summary of Contents for DE2BGHM00010100001

Page 1: ...PANNORAMIC DESK DW II 3 0 4 USER S GUIDE December 8 2021 Rev 1 ...

Page 2: ...2 System overview 16 1 2 1 Pannoramic DESK DW II system 16 1 2 2 Hardware options 18 1 2 3 Control software 19 2 Installation 20 2 1 Operation system of the control computer 21 2 2 Control computer ports 22 2 3 Connectors and Cables 23 2 4 External power supply unit 24 2 5 Power the scanner on off 24 3 Preparing Slides 25 3 1 Affixing barcode stickers to slides 26 3 2 Inserting and removing slides...

Page 3: ...6 5 2 3 Table view mode 78 5 2 4 Card collection view mode 79 5 3 Profile and preview overview on the planner 80 5 4 Progress features 81 6 Settings and Service 82 6 1 Settings 82 6 2 Service 91 6 3 Hosting 96 7 Using Profiles 98 8 Troubleshooting and Maintenance 99 8 1 Recovery functions 99 8 2 Safety information 99 8 2 1 Cleaning the device 100 8 2 2 Preventive maintenance 100 8 3 Troubleshootin...

Page 4: ...078 P0301911 PCT HU04 00019 EP 1644767 US 7327515 The above mentioned granted patents granted utility model registered trademarks pending international and national patent applications and the other corresponding IP are the sole properties of the 3DHISTECH Ltd 3DHISTECH Ltd is not liable for damage of whatever nature including but not limited to general or specific damage indirect damage consequen...

Page 5: ...ct damage consequential damage or incidental damage including damage resulting from lost profits interruption of business loss of business information pecuniary loss or similar damage that stems from or is associated with the incorporated part of this Product that is made by a third party company THE SOFTWARE IS PROVIDED AS IS AND WITHOUT WARRANTY OF ANY KIND EXPRESSED IMPLIED OR OTHERWISE INCLUDI...

Page 6: ...for Measurement Control and Laboratory Use Part 2 101 Particular requirements for in vitro diagnostic IVD medical equipment IEC 61010 2 081 2015 Safety requirements for electrical equipment for measurement control and laboratory use Part 2 081 Particular requirements for automatic and semi automatic laboratory equipment for analysis and other purposes IEC 62471 2006 Photobiological safety of lamps...

Page 7: ...fully read this instruction manual and adhere to all WARNING and CAUTION notices refer to chapter Notes Regarding Operational Safety for more information and a copy should be kept in the close to the scanner for reference whenever required This User s Guide is a part of the Pannoramic DESK DW II system identified by the following article numbers DE2BGHM00010100001 DE2BGHM00010110001 DE2BGHM0002010...

Page 8: ...key combination Example text in bold and italics Cross references within this document or to other documents Warning Can cause irreversible damage or harm to the user of the product or the product itself if this instruction is not followed Caution Can cause the product to not work properly if this instruction is not followed and alerts to a potentially critical situation Notice Calls attention to ...

Page 9: ... Crush hazard The Pannoramic DESK DW II including any of its original accessory components should not be operated in any other way than described in chapter Intended use Any of the following notes should be strictly observed Warning If operating the device other than specified by the manufacturer the level of safety will decrease Caution In the event of any non conforming type of use including non...

Page 10: ...ables without protective earth ground conductor Warning The operation of the instrument in explosion risk environments is not allowed Warning If protective devices are found to be ineffective the Pannoramic DESK DW II must be shut down and precautions must be taken to prevent unintended usage For necessary repair work or work to restore proper operating condition you should contact the 3DHISTECH C...

Page 11: ...c DESK DW II does not include any special facilities to protect from samples with an etching potentially infectious toxic radioactive or other health damaging effect You are under obligation to comply with all currently binding legislation notably national accident prevention rules when handling samples of this kind Caution Dirt or dust may adversely impact the operating capability of the Pannoram...

Page 12: ...k switch If the door is opened while a digitization process is running the process will be stopped instantly Warning A defective Pannoramic DESK DW II is not classified as domestic waste It must be properly disposed in accordance with currently valid legal requirements Warning The Pannoramic DESK DW II may not be operated by other than properly instructed persons Operating personnel must be fully ...

Page 13: ...replacement No warranty will be accepted in cases of natural wear notably wear and tear parts or improper product handling The Product Manufacturer will refuse any liability in the event of damage resulting from faulty operation negligence or unauthorized intervention into the product notably from the replacement of product parts or the usage of accessory parts from other manufacturers Any such ca...

Page 14: ... Field of View NA Numerical Aperture Virtual Slide Slide A digital image of a thin glass plate on which specimens are mounted for microscopic study a dynamic interactive image that you can manage save magnify zoom name evaluate annotate mark comment send to a colleague electronically for co operation or advice and so on Table 1 Terms and abbreviations ...

Page 15: ...the PC will highly affect the functionality of the scanner program 1 1 2 Features and benefits The Pannoramic DESK DW II offers world class brightfield whole slide scanning An outstanding 0 12 µm pixel resolution is achieved with the 40 0 95 NA equivalent to 80 magnification Plan Apochromat objective Key features of the Pannoramic DESK DW II Scanner are Capable of scanning large slides 3MP camera ...

Page 16: ...ng and information labels The following figure contains the labels used on the Pannoramic DESK DW II main unit and the external mains power supply unit Figure 1 Warning and information labels Notice The symbol at the feeder slot calls attention to bio hazardous materials in use ...

Page 17: ...it Figure 2 Main parts of the base unit 1 Protective cover 2 Sliding door 3 PointGreyGrasshopper3camera 1 2 System overview The standard scope of delivery of the product includes the following hardware and software items 1 2 1 Pannoramic DESK DW II system The following figure shows the main components of the Pannoramic DESK DW II system ...

Page 18: ...ESK DW II 3 0 4 PRODUCT DESCRIPTION MARCH 30 2021 17 Figure 3 Pannoramic DESK DW II system overview 1 24V external power supply unit 2 Pannoramic DESK DW II base unit 3 Monitor 4 Mouse 5 Control computer 6 Keyboard ...

Page 19: ...computer and monitor can vary depending on the product order Camera Camera Description Point Grey Grasshopper 3 Monochrome 1 CCD monochrome camera for normal brightfield scanning Table 2 Camera Camera adapters Camera adapter Description 0 63 adapter for Point Grey Grasshopper 3 only 1 adapter Table 3 Camera adapter types ...

Page 20: ...Option Base unit equipped with Point Grey Grasshopper 3 camera for Brightfield scanning Objectives Plan Apochromat 20 NA 0 8 Plan Apochromat 40 Corr NA 0 95 Warning Do not change correction collar settings on 40 NA objective if you need it to be set contact customer service 1 2 3 Control software Pannoramic Scanner 3 0 4 software Optional licensed features Extended focus Z stack Barcode reader Con...

Page 21: ...istants are allowed to install the hardware and software The product is ready for use after installation Caution Make sure that the device is placed so that there is enough space for ventilation and for safe and efficient operator maintenance Caution If the temperature of the location where the scanner is operated is much lower than the temperature of the equipment for example the device is brough...

Page 22: ...g exceptions of the antivirus program C Program Files 3DHISTECH C ProgramData 3DHISTECH C Program Files x86 3DHISTECH E ScannerSwap as the SWAP folder by default We recommend that you use the SWAP partition for storing temporary files generated during scanning as the lack of space required will result in interruption of scanning Microsoft Hardware Driver Updates We are not taking responsibility fo...

Page 23: ...ation of the product for a short distance by disconnecting cables and detaching hardware components from each other Figure 4 Ports on control computer 1 Status display 2 DVD drive RW 3 Power on off button 4 Earphone and microphone 3 5mm Jack ports 5 2x USB port 6 Power supply connector 7 PS 2 mouse port 8 PS 2 keyboard port 9 4x USB port 10 2x USB port 11 Network port ...

Page 24: ...tion Contact 3DHISTECH Service for support in such cases Control USB cable between scanner and control computer Preview camera USB cable between scanner and control computer Video cable between monitor and control computer Power supply cable between 230V 110V and monitor Power supply cable between 230V 110V and control computer Power supply cable between 230V 110V and external power supply unit Wa...

Page 25: ...ns power and the device Front panel 1 main power switch 2 power supply connector Back panel 3 detachable power cord to connect the external power supply unit with the main unit Figure 5 24V external power supply unit 2 5 Power the scanner on off To turn the scanner on press down the I side of the rocker switch at the front panel of the 24V external power supply unit Figure 5 1 and press O to power...

Page 26: ...Specifications of slides and coverslips Warning Always wear personal protective equipment safety goggles gloves and coat when working with biohazardous material or slides Warning Do not use a slide when it is broken or its edges are not properly cut or grounded Using such slides can lead to injury Warning Ensure that no part of the mounted coverslip protrudes from the edges of the slide Use slides...

Page 27: ...tware To affix barcode stickers to slides do the following 1 Peel off the barcode sticker 2 from the roll 2 Stick it on the colored label area 1 of the slide on the specimen side For large slides the label sticker must be applied on the left side of label area Caution Ensure that a marginal space of 1 2 mm remains on all sides between the sticker and the label area outer limits It is vital for bar...

Page 28: ...tain that the adapter is applied or not How to place and remove the adapter For the placement and removal of the adapter a special tool is needed This applicator has a magnet at its head thus allowing an easy and fast placement or removal of the adapter Figure 7 Applicator for adapter If a large slide is needed to be fed and the adapter is attached to the specimen holder it must be removed first b...

Page 29: ...he applicator 3 Put both the applicator and the adapter in a safe place 4 The specimen holder is now capable to receive a large slide Figure 10 Specimen holder with the adapter removed If you want to load normal slide into the device and the adapter is not placed on the specimen holder follow the below steps 1 Place the adapter to the head of the applicator ...

Page 30: ... onto the specimen holder Figure 11 Placing the adapter onto the specimen holder 4 After the adapter is placed on its location lift the applicator and make sure the adapter stays at its place Figure 12 Lifting off the applicator Notice The device detects the presence of the adapter and therefore preview image area is automatically modified accordingly ...

Page 31: ...well trained person Figure 13 Inserting and removing a slide 1 Click in Pannoramic Scanner 3 0 3control software The specimen holder moves to the load unload position 2 Open the slide insert door 1 by pushing it to the left Caution When opening the slide insert door fingers may be pinched during operation 3 Open the fixing lever by pulling it to the left 4 Put the slide 3 you want to scan in the s...

Page 32: ...ed person 5 Close the fixing lever by pushing it to the right so that it touches and therefore fixes the slide 6 Close the slide insert door 1 by pushing it to the right Caution When closing the slide insert door fingers may be pinched during operation Warning Never open the front door unless prompted accordingly by software When you open the door at any other time make sure not to reach with your...

Page 33: ...holder moves to the load unload position when selecting any of these two options and click Cancel to exit the window without ejecting the slide 2 Open the slide insert door 1 by pushing it to the left 3 Open the fixing lever by pulling it to the left 4 Remove the slide 3 5 Insert another slide or close the fixing lever and the door 1 Notice The slide insert door is equipped with an interlock switc...

Page 34: ...annoramic Scanner Before software initialization the user interface is opened and the mode selection icons are displayed Figure 14 Mode selection window These three mode buttons represent Microscope and Planner scanner modes and the Service mode Microscope mode for digitization of individual slide set scanning profile of the slide run Live teleconsultation use Live microscope Planner mode plan the...

Page 35: ...lowing functions are available for you to select from at the main menu bar Switch between Microscope and Planner modes Microscope initialization All motors and the preview camera during start up Brightfield mode The camera set for brightfield scanning is initialized Remote server hosting Start and host a live Teleconsultation session Load slide If there is no slide loaded into the scanner this but...

Page 36: ...a images during digitization One pixel on the monitor corresponds to one pixel on the camera The live image completely fills the display area Displays or hides the vertical and horizontal scale bars Displays the magnifier window Activates red marking on overexposed pixels Saves the current image as TIFF file to the specified location The following functions are available for you to select from the...

Page 37: ...e Image Processor Plugins o Convolute gray scale image by custom kernel o Multi channel histogram with normalization o Invert image for testing purposes o Mark overexposed pixels Scan Properties Unique settings can be defined even for each separate scanning These settings are included but not editable on the profile cards in Planner mode ...

Page 38: ...ame based on the corresponding settings set in Preferences activate Generate function Barcode parsing Select the type of barcode profile from the drop down list for slide naming though parsing the barcode string By using Default barcode profile the barcode of the slide is being matched with all the barcode types selected in the Barcode settings window Click at the left of a list item to open the B...

Page 39: ...list blank input fields will be displayed Figure 18 Create new barcode Define modify profile name in the Name input field select barcode type from the Type drop down list Define modify ranges within the barcode string when Range is selected at Parsing modes to extract necessary information Slide name Profile Case Block Root folder ...

Page 40: ... and click Create new at the top of the panel to create a new profile item Slide save path Set destination folder in the input field by typing in the path or clicking to browse for the folder Free space Free space capacity of selected local drive Conversion settings Apply conversion Turn on to convert the slide to other formats once the scanning has finished Keep original MRXS Slide The original M...

Page 41: ...verlapping o Tiled TIFF settings Click Reset to set everything to default Zero based index in names Z Stack layers of the generated TIFF files will be indexed starting with 0 and the focus distance of the actual layer will not be included inactive by default TIFF type Automatic the converter automatically selects the most appropriate method based on the size of the source slide Force simple tiff T...

Page 42: ...100 Zoom scale set the level of zoom at which the TIFF image is created to get the smallest file size possible o DICOM settings Click Reset to set everything to default Frame number maximum default 0 Optical path frame default 3 Pixel size accuracy default 7 X Y offset accuracy default 5 Depth accuracy default 3 Tile pool size default 1000 UTC time in minutes default 0 Basic offset table active by...

Page 43: ...s is displayed in the Converter queue window of the converter Figure 20 Conversion window o Other settings Scan separately The FOV areas of the preview image will be scanned and saved separately as discrete digital slides Scan to Server Figure 21 Scan to Server settings Server settings ...

Page 44: ...indow Display Name Host Name Protocol Figure 22 Window of server editor Server Editor stores each of the created server in a list List entries can be removed or a new entry can be added if required With the Filters function you can narrow down the results by searching for a specific server data By double clicking a list item server data will be loaded in the Scan to Server panel After loading serv...

Page 45: ...arcode settings for parsing can be modified in the Barcode Editor window Figure 24 Barcode Editor If using MIL for barcode reading you can select the following barcode types 1D barcode types Code 39 Code 128 Code 16K Interleaved 2 of 5 Standard 2 of 5 IATA 2 of 5 Matrix 2 of 5 Telepen Code 93 Code 11 MSI Codabar Patch Code Pharmacode EAN 13 EAN 8 ...

Page 46: ... in CaseCenter is automatically selected as scanning destination based on the CaseID containing slide and patient data stored on HIS LIS Therefore Folder Case Block and Slide name field data cannot be modified only a profile can be selected Activate Generate to create slide name automatically based on the criteria defined in the corresponding settings of the Preferences window Activate the option ...

Page 47: ... want to scan from the Server drop down list Click the arrow to show the list of saved server profiles or click Add new item at the bottom of the list to create another server connection When creating another server connection define the following details of the server in the Server Editor window Display Name Host Name Protocol User name Is DX server Figure 26 Window of server editor ...

Page 48: ...e panel After loading server data User name and Password are required to be added for authentication and accessing the server If connection is successful a green checkmark is displayed in the window Figure 27 Connecting to server is successful Conversion settings Figure 28 Conversion settings For parametrization and settings refer to Conversion settings at Scan to Local panel see above Caution At ...

Page 49: ...Settings for more information HIS Integrated output This folder contains converted slides where barcode reading was successful and they can be connected to a HIS case Unidentified output This folder contains converted slides where no barcode is available or barcode reading was not successful These slides are scanned with a default profile Conversion progress is displayed in the Converter queue win...

Page 50: ...ontaining a list of previously saved profiles is opened Additional profiles can be created after clicking Create After expanding the Filter section of the panel search for a specific profile can be initiated by filtering based on the following data Profile name Objective type Confocal mode Multilayer mode Filters Modify date Last used date ...

Page 51: ... Profile The selected profile can be saved in this window after typing the profile name into the text field and clicking Save as Note that this function is not available in Planner mode Figure 32 Save profile Reset Zoom This function is active only in Live view at 1 1 magnification Live image magnification Settings and Service function descriptions are detailed in chapter Settings and Service Help...

Page 52: ...re information In accordance with the selected mode the Profile Settings Panel and the Microscope Control Panel views are modified 5 1 Brightfield scanning mode Microscope View consist of three different sections Main functions Located at below the window header these functions are not identical in microscope and planner modes Functions such as Live mode Remote server hosting Objective selection P...

Page 53: ...s for scan profile Limits of the range You can define focus limits by defining the upper and lower limits by selecting the desired value in the selection boxes This is useful if focusing was not targeted on the specimen but on a spot on the coverslip Focus distance the distance of focal points can be set to create a focus map based on which the software calculates interpolated focus values one ste...

Page 54: ...croscope for scanning the slide This option is recommended when scanning in Brightfield mode Thresholding The manually specified value is used for thresholding during scanning Preview image of the loaded slide is displayed in the Preview window and when modifying any of the parameter values it will have effect on the preview image If the threshold value presented on the Microscope Controller previ...

Page 55: ...threshold value manually or append missing areas with the help of appropriate functions in the Preview window o Use marker with threshold If the specimen cannot be identified as required for digitization for example weak contrast it can help to encircle completely the specimen with a black marker pen You have to draw a full circle with the pen to enable the detection Marker pen detection will make...

Page 56: ...ea selected not selected Threshold enhancement o Remove coverslip If selected the edges of the coverslip are not detected as specimen to be scanned Depending on the threshold level it is possible that the edges of the coverslip are detected as areas to be digitized Figure 39 Preview image with and without coverslip edge ...

Page 57: ...e maximum size of specks not to be digitized by adjusting the slider o Dilate mask Adjust the slider to enlarge or decrease the scanned area The edge is extended discretely by 100 µm each time Scanmap A previously saved scanmap can be loaded and applied Use Threshold The defined preview settings are applied as the basis of scanmap Loaded scanmap This function is useful if the slides contain areas ...

Page 58: ...evels with the Levels selection box The current focus value is the initial level If you set 5 for example then the initial level plus four two focus levels above and below the FOVs are captured Therefore it is advised to choose an odd number for the focus levels Separate layers are created and stored this way and can be opened with Viewer applications The Z Stack slide contains the extended focus ...

Page 59: ...e the following predefined image formats and a subsequent custom option from the Image Quality drop down list in the Image Encoding section of the window Excellent JPEG 90 Good JPEG 80 Medium JPEG 60 Low JPEG 30 Custom If choosing this option compression setting becomes available and you can also select from different image formats Accordingly further adjustments can be made except if PNG or BMP i...

Page 60: ... software will not create new compensation images for each slide Compensation images are reference images used for white balancing and shading With Save focus quality the measurement of focus quality correctness of average focus on layers is saved This option is inactive when Extended focus option is activated Save image in original Bayer size function is non applicable for DESK 5 1 2 Microscope c...

Page 61: ...ly saved Scanmap from file Custom Scanmap Preview Type setting determines the type of illumination In Brightfield mode the following preview types are available Brightfield preview a normal type of illumination in the microscope for scanning the slide This option is recommended when scanning in Brightfield mode Remove Coverslip If selected the edges of the coverslip are not detected as specimen to...

Page 62: ...od smear the Remove Coverslip function cannot be activated and focusing on the coverslip area is not available If you want to use the Remove Coverslip function first switch to Custom Scanmap Fill holes inside scanmap If selected the holes inside the specimen will also be scanned Often these holes contain small sample objects that otherwise would not be scanned Remove specks If selected the scanner...

Page 63: ...e areas will be digitized however this may also include specks or other imperfections of the slide Greater values result in a less sensitive scanning but it is possible that some of the smaller specimen areas will not be digitized Use marker with threshold If the specimen cannot be identified as required for digitization for example weak contrast it can help to encircle completely the specimen wit...

Page 64: ... everything within the marked area check the Scan everything within marker selection box Figure 45 Scan everything within the marker selected not selected Dilate mask Adjust the slider to enlarge or decrease the scanned area The edge is extended discretely by entering a new value each time To switch to manual mode click the top left corner of the button and the required value can be entered in the...

Page 65: ...lide click Position sample and then click on the area of interest on the preview image This will define the Live image that you can access from the Live view Union Add the selected areas to the preview Mark area for scanning based on the shape selected in the Preview Toolbar This area will not be scanned Erase Delete selected areas from the preview image Deselection is made based on the selected s...

Page 66: ... scanned with the different tools on the Preview toolbar Place focus point You can add manual focus points on the preview image the coordinates of the manual focus points you add are listed on the Focus settings panel NOTE The maximum number of focus points that you can manually add is 100 Rectangle tool Draw rectangle shaped area Ellipse tool Draw ellipse selection Polygon tool Area selection by ...

Page 67: ...TMA tool Grid selector Delete TMA grid by clicking the X at the top right corner and rotate grid by clicking the icon at the bottom right corner Enter the number of rows and columns in the Rows and Columns fields or select the appropriate values with the arrows Enter the distance between two spots on the X and the Y axis in µm in the Core distance fields or select the appropriate values with the a...

Page 68: ...s selected a black frame displayed in the image and only the area inside the box is scanned It is useful if you only want to scan the area that is equivalent with the size of the coverslip so external specks will not be scanned Figure 50 Use selection box The following colors are used in the preview image to demonstrate digitization and selection settings Figure 51 Colors in preview image and Labe...

Page 69: ...iew panel the preview camera detects the marker pen The inside areas appear in red color and will be digitized Areas scanned in This color is only displayed during scanning Hide all layers All the layers will be hidden existing but not visible The original preview image is shown but layer information is still valid Note that while this function is active none of the other preview functions can be ...

Page 70: ...et the upper and lower limits by selecting the desired value in the selection boxes By using Set Range the Lower limit value is set to 32 of the current focus value and the Upper limit value is set to 32 of the current focus value This is useful if Auto Focus does not find the focus on the specimen but on the coverslip Also this makes the focusing sequence faster For manual focusing define the man...

Page 71: ...gs window An image is defined as a two dimensional function f x y the amplitude of at any pair of coordinates x y is called the intensity or gray level of the image at that point The pixel intensity at the coordinate pointing at with the cursor is displayed in the Image Intensity window Figure 55 Window of Image Intensity 5 1 2 4 Stage positioning Click to activate Stage Positioning Tool to naviga...

Page 72: ...ve to the required direction with the set step size 5 1 3 Quick preview functions Use Ctrl mouse wheel to zoom in or out to the preview area or the Live image A quick preview function tool pops up by right clicking to the preview area It allows a quick access to main preview related functions Drag Draw Erase Retake preview Settings o Toggle deletion always on top o Reset zoom o Window auto size o ...

Page 73: ...functions tool can be displayed upon right clicking on the background of the main window outside the preview window It includes quick access buttons to main functions for DESK DW II Figure 58 Quick toolset for microscope Autofocus Live tools o Fast mode o Screenshot o Magnifier o Ruler o Image processor plugins o Add scanmap ...

Page 74: ...inked in a row displayed at the bottom left corner of the main window Figure 59 Progress of the profile modification history Once you are moving the mouse cursor over a unit all the parameters will become visible in a pop up window Figure 60 Details of parameter modification For the easier perspicuity modifications can be observed in a pop up window by clicking the button in which both the origina...

Page 75: ...D SETTINGS MARCH 30 2021 74 Figure 61 Profile history tree 5 2 Planner mode The whole scanning procedure of the loaded slide can be planned in this mode Virtual slides can be created and stored in different folder or server Figure 62 Planner mode ...

Page 76: ...Slide view with card mode Load slide Available after initialization upon clicking the slide icon the slide can be loaded Remove Change slide Available only if a slide is loaded into the scanner Click this button to remove or change the slide Scan to inactive Available after loading procedure unique settings can be defined even for each separate scanning Start scan inactive Scanning of the actually...

Page 77: ...de view with card Click in the Preferences window Planner layout selector to activate this view in which the slide position and its card can have a horizontal or vertical layout Slide preview and the list of the assigned profiles are displayed Figure 63 Vertical Slide view with card ...

Page 78: ...ontal Slide view with card The parameters of the assigned profile are displayed in a card Figure 65 Brightfield profile card The following information are included in a profile card Profile name in the top left corner Profile status is marked with spots of different color o Stored o Edited ...

Page 79: ...ile editor for Scheduler Notice Once scanning has finished the thumbnail of the digital slide is added to the card at the bottom Double click the thumbnail image of the digital slide to open it in Viewer If scanning is performed to a local destination the digital slide can be opened in CaseViewer only but when scanned to CaseCenter it can be opened in InstantViewer as well depending on the setting...

Page 80: ...ded profile Profile name Illumination Objective type Filters N A Progress Properties The location of the virtual slide with the selected profile can be defined Scan result Scan duration Scanned FOVs Total FOVs 5 2 4 Card collection view mode If you click the button each of the slide previews are displayed in the window Figure 67 Window of Card collection view mode ...

Page 81: ...es can be checked here The expanding panel at the right side includes all the profile settings in coherence with the view type of the Profile Setting panel Slide preview is displayed in the Preview window in which the scanmap can be modified until beginning the scanning process Figure 68 Selected profile and expanded Preview window in Planner mode ...

Page 82: ...e and Planner modes whenever there is a running hardware operation or scanning procedure Progress content can be therefore different depending on the type of the running procedure Figure 69 Progress data The following information is included in the progress log list during scanning Scanning time Location Slide name Free space FOV count ...

Page 83: ...ate Services by clicking and Settings by clicking at the right side of the main menu bar 6 1 Settings Activate Settings by clicking at the right side of the main menu bar Preferences This panel contains user settings that have global effect on the GUI and some of its functions Figure 70 Settings ...

Page 84: ... SlideScanner Globalization contains another language file that language can be set in this drop down menu too Appearance settings o View Mode Selector Text mode Icon mode Float Text mode Float Icon mode o Style selector Black Jelly Flat style Black Jelly light Flat style light o Planner style editor Slides with card Table Card Collection o Preview window start position Initial position Last posit...

Page 85: ...Screenshot folder Set the folder for storing screenshots by clicking Browse Otherwise the C Users Username Pictures folder is used by default Slide settings o Unload slide after FL grabbing N A o Slide label anonymity Slide label area is displayed as a clear white image during scanning patient data will not be visible in CaseViewer o Do not save label to slide The original label area is not saved ...

Page 86: ...STECH SlideScanner HWLogDataBase The following motor movements are recorded in the log list General Microscope Part Objective Changer Preview Light Relay Scan Loader Service Slide Scanner Stage o Software log All the circumstances and states of the slide scanning procedure are saved LogID is the sequence number of scanning performed on the scanner in use Profile Name Illumination mode Scan type Sc...

Page 87: ...c settings o On this panel you can define the Swap file location and set the Number of compensation images for preview camera if needed o If a certain time is set for Watchdog timeout the scanning process is canceled after this time It is not recommended to set Watchdog timeout for FL scanning as these processes can take several hours o If you Enable plan autosave for more comfortable and safer us...

Page 88: ...gure 73 Profile behavior settings o Use profile history save With this function each profile modification is saved in Profile History from which the different stages can be reloaded o Save interval Profile content is automatically saved at the specified timeframes o Enable setting of focus time Parameters Short Normal Long related to focus time will be enabled on the profile settings panel Normal ...

Page 89: ... can define the external software by entering the file path in the Application box or by browsing for it by clicking If you define parameters in the Parameters field it will pass them to the software that it starts If no parameter is defined then the parameter will not be passed The default parameters are the following For Slide scanning has finished SLIDENAME transfers the slide name For Scanning...

Page 90: ...nd set the message body in the Message subject field by entering a text for example to inform recipients on the location of the scanner or the slide set you are working with Click to test settings by sending an e mail to the address defined in the E mail To field after you have finished to check their relevancy before applying them First click SMTP setup to display the E mail settings window in wh...

Page 91: ...ion Click Delete user if you want to remove a user from the list after selection Report sender settings Figure 76 Report sender settings Add new recipients to the list by clicking or remove selected from the list by clicking To send an example mail to the selected recipient click Open E mail settings window to modify recipient data by clicking Emergency slide functions This panel contains control ...

Page 92: ...ARCH 30 2021 91 6 2 Service Activate Service by clicking at the right side of the main menu bar Service password Enter password first to enable service settings for modification Figure 77 Enter service password Camera settings Figure 78 Camera settings ...

Page 93: ... profile has effect on the color set color temperature and gamma value of the scanned image Preset profiles are the following Calibrated Linear Color scheme is defined by calibration Gamma value is not included sRGB standard Color scheme is defined by calibration standard Gamma value 2 2 is applied sRGB standard Microscope Like Color scheme is defined by calibration standard Gamma value White Poin...

Page 94: ...ox o Reset all camera rotation Click this button to set camera rotation values to default Save settings by clicking Image compensation You can use a saved compensation image whenever compensation related issues occur deriving from the slide illumination staining or embedding medium irregularities Figure 79 Image compensation window o BF cameras field displays the active camera Currently there is o...

Page 95: ...button to interrupt the process The progress bar at the bottom of the window displays the progress of the compensation image creation o Export image Save compensation image Barcode settings By predefining barcode settings you enable the Read Barcode option when using the Pannoramic Scanner 3 0 4 control software Figure 80 Barcode settings ...

Page 96: ...e figure correctly or there is no barcode in the barcode area the software will display the following error message Barcode detection unsuccessful There might be no barcode present o Barcode reader library Select MIL barcode library or Embedded barcode library o General Barcode settings Inverse barcode color Activate to invert foreground and background colors of the barcode Use barcode compensatio...

Page 97: ...Exclude check digit Checksum value is ignored when reading Interleaved2of5 and Code39 barcode types 6 3 Hosting Hosting a live teleconsultation session gives specialists the opportunity to examine the same Live microscopic image during a real time counseling even if being in laboratories far away from each other This means multiple users can connect to the device at the same time The user of the s...

Page 98: ...sting a teleconsultation session 1 Select Hosting from the microscope mode menu 2 Type in your nickname used during the session 3 Click to start hosting the session 4 The software displays the hosting address and the port number Figure 81 Teleconsultation host data Join teleconsultation as a client 1 Start the Lite version of the Pannoramic Scanner 3 0 4 software 2 Type in your nickname used durin...

Page 99: ...s quality ON OFF Use of Stitching ON OFF Determination of the area to be scanned Use of automatic threshold specimen Use of specimen threshold value Use of marker pen threshold and specimen threshold values Remove coverslip function ON OFF Use of scan everything within marked area function ON OFF Filling of holes ON OFF Use of removing specks according to the set value ON OFF Use of saved scan are...

Page 100: ...nsure click No For more comfortable and safer use the Planner autosave function allows the taking of automatic backups while creating a scan plan The backups are placed in the default document folder of the actual windows user and can be loaded by clicking the Load plan button 8 2 Safety information Check cables plugs and connections before operation and if defective or cannot be replaced contact ...

Page 101: ...onnect the power plug before changing the bulbs Defective devices do not classify as domestic waste Dispose of the device in compliance with the currently valid legal requirements 8 2 1 Cleaning the device Before cleaning switch off the device and pull the plug out Do not let liquid penetrate into the system To clean liquid from the device use a lint free cotton cloth You can moisten the cloth wit...

Page 102: ...sts and is open in Pannoramic Viewer Close virtual slide in Pannoramic Viewer Slide jammed 1 Exit the Pannoramic Scanner 3 0 4 control software 2 Switch off the power supply and disconnect the power cable 3 Remove the protective cover of the Pannoramic DESK DW II Follow the steps in chapter Removing the protective cover 4 Remove slide manually see chapter Removing a slide 5 Reattach protective cov...

Page 103: ...ncorrectly Guiding fault in transport system Contact 3DHISTECH Service for support Digitization process is extremely slow Extended focusing option is activated Deactivate the Extended focusing option if not required Z stack option is activated Deactivate the Z stack option if not required Image is out of focus Focus range limit is activated Deactivate the Limiting focus range option Focus range se...

Page 104: ...ve cover To perform maintenance work and because of slide jamming the protective cover of the Pannoramic DESK DW II need to be removed to eliminate the problem First make sure that the running digitization procedure is interrupted prior opening the cover Before removing the cover exit the Pannoramic Scanner 3 0 4 control software switch off the 24 V power supply and disconnect the power cables Cau...

Page 105: ...4 Note that the rear part of the cover must be pushed over the top part of the blue basic unit 7 5 To lock the cover in place insert the screws again and fasten them Caution Make sure that no cables are squeezed as you replace the cover s 8 4 2 Removing a slide If a slide got jammed or has suffered breakage during the process of digitization stop the process and if possible move the slide holder t...

Page 106: ...emove the slide 1 from the holder 2 Warning If the slide is broken make sure to remove all pieces completely from the device The edge of the broken area of the slide is sharp and it can lead to injury and contagion Broken slide can be removed only by a well trained person 6 Swing fixing lever 3 back to the right towards the holder 7 Reattach the cover see chapter Removing the protective cover 8 Co...

Page 107: ... transporting One or two persons can carry the base unit by holding it by its base plate You can find the weight data of the base unit in chapter Technical Data Caution Be sure that the scan camera is not moved during transportation To transport Pannoramic DESK DW II do the following 1 Turn power supply off and detach all cables 2 Transport Pannoramic DESK DW II 3 After finishing transportation re...

Page 108: ...24 3 kg 24V 100W power supply approx 550 g Ambient conditions Transportation Shipment packed Permissible ambient temperature 40 C to 70 C Storage Permissible ambient temperature 0 C to 60 C Permissible relative air humidity non condensing 25 75 Operation Permissible ambient temperature 10 C to 35 C Permissible relative air humidity 25 75 Altitude at installation site max 2000 m Atmospheric pressur...

Page 109: ...e with EN 61326 2 6 2012 Base unit input voltage 24V DC 1V Power consumption of the complete device 60 VA SINPRO MPU101 108 24V external mains power supply unit Intended site closed room facilities Electrical protection class I Internal protection degree IP 20 Electrical safety in compliance with UL 2601 1 TÜV EN 60601 CE EN60601 1 2 2001 Over voltage category II Radio interference suppression in ...

Page 110: ... 3 2 um x 3 2 um Max frame rate 13 Hz Bit depth 8 10 bit Scan camera Point Grey Grasshopper 3 GS3 U3 51S5M C Global Shutter Type CMOS Sony IMX250 Pixel size 3 45µm 3 45µm Camera resolution 2448 H 2048 W pixel Frames rates 75 fps Bit depth 10 bit 12 bit Pixel resolution with 20x objective and 0 63x C mount adapter 0 27µm Pixel resolution with 20x objective and 1x C mount adapter 0 17µm Pixel resolu...

Page 111: ...m requirements Operating System Microsoft Windows 10 Professional 64 bit EN CPU Intel Core i5 8600 RAM 32GB DDR3 1600 Hard disk 500 GB Optical drive DVD RW Display 96 dpi Graphics SXGA 1280 1024 True color Input devices Keyboard mouse Ports 2 x Fire Wire 1394 A 1394 B 4 x USB 2 0 GB Ethernet ...

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