29
28
7. THE USE OF HEMP FLOWERS
After consulting your physician, if your
doctor recommends that you are able
to determine your requirement for
active ingredients yourself (titration),
due to the relatively rapid effect (ap-
prox. 1-2 minutes), you may put higher
quantities cannabis (up to 500 mg)
into the Filling Chamber and vaporize
at lower temperatures.
Thus, you can fill mutiple Valve Bal-
loons with vapors of active ingredients
with a single Filling Chamber filling.
With this method no reproducible
doses are achieved; for this reason,
it is only appropriate for experienced
users.
When observing the Instructions
for Use and with a vaporization tem-
perature of 185°C (365°F) the follow-
ing reference values are validated in
studies:
When observing the Instructions for Use and with a vaporization temperature of
210°C (410°F) the following reference values are validated in studies:
If dosage is too low increase the amount of cannabis.
If dosage is too high reduce the vaporization temperature.
Drug (Filling
Chamber Content)
Bedrocan (100 mg)
Bediol (100 mg)
THC: approx. 19 mg
THC: approx. 6 mg
CBD: approx. 7,5 mg
approx. 8 mg
approx. 3,5 mg
approx. 4,5 mg
approx. 5,5 mg
approx. 2,4 mg
approx. 3 mg
Cannabinoid
content in drug
Cannabinoid con-
tent in Valve Balloon
after vaporization
with 210°C (410°F)
Cannabinoid
content in blood
stream (systemic
bioavailability)
after inhalation
7. THE USE OF HEMP FLOWERS
The charts show the concentration of active ingredients approx. 5 minutes after
the filling of the Valve Balloon. Due to exhalation the actual systematic bioavail-
ability (blood content) is approx. 35% lower than the cannabinoid content in the
Valve Balloon.
Cannabinoid concentration per Balloon Filling at 185°C (365°F) with 250 mg filling quantity
mg
10
8
6
4
2
0
1 2 3 4 5 6 7 8 9 10
Bedrocan (THC)
Bediol (CBD)
Bediol (THC)
Multiple Balloon
Fillings from a single
250 mg sample
Cannabinoid concentration per Balloon Filling at 185°C (365°F) with 500 mg filling quantity
mg
Multiple Balloon
Fillings from a single
500 mg sample
10
8
6
4
2
0
1 2 3 4 5 6 7 8 9 10
Bedrocan (THC)
Bediol (CBD)
Bediol (THC)