Vapormed VOLCANO MEDIC, Инструкция по эксплуатации

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6. THE USE OF DRONABINOL
Use only approved dronabinol (THC)
that is sold to pharmacies for making
up prescriptions.
The pharmacy produces an alcohol
solution according to your physician‘s
prescription (generally 2.5% THC) for
inhalation with the VOLCANO MEDIC
Vaporization System.
6.1. Efficiency of vaporized
Dronabinol (THC)
By following the procedure listed in
the Instructions for Use the systemic
bioavailability of vaporized dronabi-
nol is approximately 40%.
For comparison: The systemic bio-
availability of cannabinoids adminis-
tered orally is below 15%.
When observing the Instructions for Use and with a vaporization temperature of
210°C (410°F) the following reference values are validated in studies:
If dosage is too low increase the amount of dronabinol.
If dosage is too high reduce the amount of dronabinol.
Drug (Filling
Chamber Content)
Dronabinol/THC
(10 mg)
THC: 10 mg approx. 6 mg approx. 4 mg
Cannabinoid
content in drug
Cannabinoid con-
tent in Valve Balloon
after vaporization
with 210°C (410°F)
Cannabinoid
content in blood
stream (systemic
bioavailability)
after inhalation
6. THE USE OF DRONABINOL
Preparation to use the Liquid Pad
When using dronabinol (THC) dis-
solved in alcohol, the Screens in the
Filling Chamber are not needed and
should be removed.
The Liquid Pad is inserted in the Fill-
ing Chamber instead of the lower
Screen.
Applying drops with a pipette
6.2. Preparation
Make sure to use the Mouth-
piece only with attached Lip
Piece before every operation
(see Chapter 9.3. “Disposable MED-
IC VALVE
Lip Piece for Hygienic Use”,
page 39)
Turn the Filling Chamber Cap counter-
clockwise in order to remove it from
the Filling Chamber.
Remove Filling Chamber Cap
Dronabinol (THC) dissolved
in oil is not suitable for vapori-
zation and is intended for oral
administration.
6.3. Application
Turn the Filling Chamber upside down
and use a pipette to drop the dronabi-
nol (THC) dissolved in alcohol onto
the center of the bottom of the Liquid
Pad. The Liquid Pad can hold up to
20 drops.
At the beginning of treatment, apply a
maximum of two drops and carefully
increase to the appropriate dosage.
Always follow your doctor‘s recom-
mendations!
Next screw on the Filling Chamber
Cap again.