CoaguChek Professional Monitoring Systems
Training Manual
73
In general, INR differences between
POC devices such as CoaguChek®
systems and laboratory systems are
of the same order of magnitude
as those observed between various
laboratory systems
10
Experience has shown that measure-
ment deviations are generally observed
between different coagulation measure-
ment systems, independently of whether
POC or laboratory
6
1/20/2015 8:49:46 AM
In general, INR differences between POC devices such as CoaguChek systems and labora-
tory systems are of the same order of magnitude as those observed between various labo-
ratory systems.
10
There are no specific measurement differences between the CoaguChek
system and the laboratory. Measurement deviations are generally observed between differ-
ent coagulation measurement systems, independently of whether POC or laboratory.
The following points generally apply to measurement deviations:
· Deviations are more common in patients with unstable anticoagulation, in whom coagu-
lation factors are even more variable. In addition, the likelihood of measurement differ-
ences is increased further by different reagents sensitivities
· In general, the higher the INR, the greater the possible deviations may be:
11
· INR below 2.5: possible deviation 0.1 – 0.3 INR
· INR 2.5 – 4.5: possible deviation 0.5 – 1.0 INR
· INR above 4.5: possible deviation 1.0 – 2.0 INR
· In cases of differences between values obtained using laboratory systems and Coagu-
Chek devices, check whether a systematic offset exists between the CoaguChek device
and the specific laboratory. A systematic measurement offset against one laboratory
method does not mean that the measured value offset will exist against other laboratory
methods
· It should be noted that for patients taking VKAs with previously stable therapeutic INRs
who present with a single out-of-range INR of ≤0.5 below or above therapeutic, recent
guidelines suggest continuing the current dose and testing the INR within 1 to 2 weeks
12
· In case of unclear readings, it is advisable to not change between systems
INR differences between CoaguChek
and the laboratory are normal
Between-laboratory measurement differences
are of similar magnitude
7
1/20/2015 8:49:57 AM
In general, INR differences between POC devices such as CoaguChek systems and labora-
tory systems are of the same order of magnitude as those observed between various labo-
ratory systems.
10
There are no specific measurement differences between the CoaguChek
system and the laboratory. Measurement deviations are generally observed between differ-
ent coagulation measurement systems, independently of whether POC or laboratory.
The following points generally apply to measurement deviations:
· Deviations are more common in patients with unstable anticoagulation, in whom coagu-
lation factors are even more variable. In addition, the likelihood of measurement differ-
ences is increased further by different reagents sensitivities
· In general, the higher the INR, the greater the possible deviations may be:
11
· INR below 2.5: possible deviation 0.1 – 0.3 INR
· INR 2.5 – 4.5: possible deviation 0.5 – 1.0 INR
· INR above 4.5: possible deviation 1.0 – 2.0 INR
· In cases of differences between values obtained using laboratory systems and Coagu-
Chek devices, check whether a systematic offset exists between the CoaguChek device
and the specific laboratory. A systematic measurement offset against one laboratory
method does not mean that the measured value offset will exist against other laboratory
methods
· It should be noted that for patients taking VKAs with previously stable therapeutic INRs
who present with a single out-of-range INR of ≤0.5 below or above therapeutic, recent
guidelines suggest continuing the current dose and testing the INR within 1 to 2 weeks
12
· In case of unclear readings, it is advisable to not change between systems
INR differences between CoaguChek
and the laboratory are normal
Between-laboratory measurement differences
are of similar magnitude
7
1/20/2015 8:49:57 AM
11
In general, INR differences between POC devices such as CoaguChek systems and labora-
tory systems are of the same order of magnitude as those observed between various labo-
ratory systems.
10
There are no specific measurement differences between the CoaguChek
system and the laboratory. Measurement deviations are generally observed between differ-
ent coagulation measurement systems, independently of whether POC or laboratory.
The following points generally apply to measurement deviations:
· Deviations are more common in patients with unstable anticoagulation, in whom coagu-
lation factors are even more variable. In addition, the likelihood of measurement differ-
ences is increased further by different reagents sensitivities
· In general, the higher the INR, the greater the possible deviations may be:
11
· INR below 2.5: possible deviation 0.1 – 0.3 INR
· INR 2.5 – 4.5: possible deviation 0.5 – 1.0 INR
· INR above 4.5: possible deviation 1.0 – 2.0 INR
· In cases of differences between values obtained using laboratory systems and Coagu-
Chek devices, check whether a systematic offset exists between the CoaguChek device
and the specific laboratory. A systematic measurement offset against one laboratory
method does not mean that the measured value offset will exist against other laboratory
methods
· It should be noted that for patients taking VKAs with previously stable therapeutic INRs
who present with a single out-of-range INR of ≤0.5 below or above therapeutic, recent
guidelines suggest continuing the current dose and testing the INR within 1 to 2 weeks
12
· In case of unclear readings, it is advisable to not change between systems
INR differences between CoaguChek
and the laboratory are normal
Between-laboratory measurement differences
are of similar magnitude
7
1/20/2015 8:49:57 AM
Summary of Contents for CoaguChek XS Plus
Page 1: ...CoaguChek Professional Monitoring Systems Training Manual...
Page 4: ......
Page 5: ...CONTACT AND ORDER DETAILS...
Page 6: ......
Page 8: ......
Page 9: ...SYSTEM INTRODUCTION...
Page 10: ......
Page 16: ......
Page 17: ...INTERFERENCES...
Page 18: ......
Page 22: ......
Page 23: ...TRAINING...
Page 24: ......
Page 28: ......
Page 30: ......
Page 34: ......
Page 36: ......
Page 37: ...CLEANING...
Page 38: ......
Page 44: ......
Page 45: ...TROUBLESHOOTING...
Page 46: ......
Page 49: ...APPENDIX 1...
Page 50: ......
Page 65: ...APPENDIX 2...
Page 66: ......
Page 67: ...Accuracy and precision in oral anticoagulation monitoring I know my value...
Page 77: ......