7.2 Aerosol characteristics according to
ISO 27427
The aerosol characteristics presented in these instructions for
use were determined in accordance with ISO 27427 using Sal-
butamol. If other solutions or suspensions are used for
nebulisation, the aerosol characteristics may differ from the val-
ues shown (particularly if they have greater viscosity).
The following data is based on tests according to a standard
which takes adult breathing patterns as a basis. Therefore,
these figures will probably differ from corresponding figures
that were calculated for populations of children and infants.
Nozzle insert
(transparent)
Minimum
compressor
flow
(3 l/min. –
0.6 bar)
Nominal
compressor
flow
(4 l/min. –
1.2 bar)
6
Maximum
compressor
flow
(6 l/min. –
1.9 bar)
MMAD [µm]
7
5.4
4.5
3.4
GSD
8
2.13
2.23
2.31
Respirable fraction
[% < 5 µm]
44.0
53.2
66.2
Aerosol fraction
[% < 2 µm]
11.6
17.9
28.1
Aerosol fraction
[% > 2 µm < 5 µm]
32.4
35.3
38.1
Aerosol fraction
[% > 5 µm]
56.0
46.8
33.8
Aerosol output [ml] 0.30
0.40
0.38
Aerosol output rate
[ml/min]
0.09
0.12
0.14
6) Operation with PARI COMPACT2 compressor (Type 152).
7) MMAD = Mass Median Aerodynamic Diameter
8) GSD = Geometric Standard Deviation
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