Cryotherm BIOSAFE 120 Operating Manual Download Page 8

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Cryogenic Storage Vessels CHRONOS®120/220/420

Cryogenic Storage Vessels
CHRONOS

120/220/420

3.1 Specifications of the Vessels

CHRONOS

120/220/420

CHRONOS

120

CHRONOS

220

CHRONOS

420

1. Width B

56 cm

72 cm

90 cm

2. Depth T

70 cm

85 cm

103 cm

3. Total height of Vessel H

(cover closed)

112 cm

120 cm

119 cm

4. Assembly width A

80 cm

96 cm

5. Assembly depth D

80 cm

75 cm

95 cm

6. Assembly width

BIOSAFE-CONTROL

80 cm

95 cm

110 cm

7. Height with

BIOSAFE-CONTROL

125 cm

Summary of Contents for BIOSAFE 120

Page 1: ...Operating Manual BIOSAFE 120 220 420 MD Service Hotline 49 0 2741 95 85 75...

Page 2: ......

Page 3: ...on 13 4 Level Control Unit and Vessel Control System BIOSAFE CONTROL 14 4 1 Functions 14 4 2 Operating Elements 23 4 3 Assembly Commissioning 24 4 4 Normal Operation 24 5 Safety 26 5 1 Safety advices...

Page 4: ...20 42 8 1 2 Sorting System CHRONOS 220 45 8 1 3 Sorting system CHRONOS 420 48 9 Maintenance Repair 52 9 1 Scope of Maintenance 52 9 2 Declaration of Decontamination 54 9 3 Spare Parts 55 10 Faults 56...

Page 5: ...d components e g erythrocytes heart valves skin bones teeth as well as e g samples for the DNA analysis in gene technology The preconditions for this are that the samples are tightly packed in packagi...

Page 6: ...bsolutely necessary to read the operating manual completely The BIOSAFE 120 220 420 MD may only be operated by trained and instructed personnel Immediately after receipt of the unit check delivery wit...

Page 7: ...HRONOS 120 220 420 Cryogenic Storage Vessel CHRONOS 120 220 420 with designer cover with vacuum insulated panel solenoid valve cover switch and safety intermediate piece under a cover insulated decant...

Page 8: ...0 220 420 CHRONOS 120 CHRONOS 220 CHRONOS 420 1 Width B 56 cm 72 cm 90 cm 2 Depth T 70 cm 85 cm 103 cm 3 Total height of Vessel H cover closed 112 cm 120 cm 119 cm 4 Assembly width A 80 cm 80 cm 96 cm...

Page 9: ...cm 107 cm 9 Space required Depth F 91 cm 116 cm 10 Space required Width G 141 cm 175 cm 11 Space required Distance J 42 cm 62 cm 12 Space required Distance J1 55 cm 75 cm 13 Space required Height H3 1...

Page 10: ...al capacity 151 251 415 l Geometrical capacity below the storage shelf LIN reserve 21 35 57 l Geometrical capacity above the storage shelf cubic capacity 130 216 358 l 1decimetre filling height corre...

Page 11: ...ds and stairs with 2 persons Transport with fork lifter The CHRONOS 120 Vessel can be transported with a fork lifter Special fork lifter pockets are not provided Therefore it is absolutely necessary t...

Page 12: ...nt area there exists the corresponding accommodation for hemispherical journals of the transport device marked with a green arrow label By means of the transport device the vessel is slightly lifted i...

Page 13: ...A lock is integrated in the cover Thus the access to the contents of the vessel is limited Danger at the lock trapping of the fingers For handling the cover two cover handles are provided The handles...

Page 14: ...e spring is adjusted in such a way that the cover cannot leave the vessel completely itself This pressure ensures the perfect function of the cover opening mechanism The pressure inside the gas pressu...

Page 15: ...Danger at the lock trapping of the fingers EMERGENCY PROCEDURE In case that the lifting mechanism is obviously blocked with closed or opened cover carry out the following emergency procedure after co...

Page 16: ...cture The level probe of BIOSAFE CONTROL is inserted into the splash guard pipe center provided for this Left picture Between the LIN fill line left and the splash guards pipe right for the level prob...

Page 17: ...detachable 3 8 screwed pipe At this connection the decanting of the LIN supply is connected The fill pipe ends inside the vessel below the cover insulation and is slightly bevelled It prevents the sp...

Page 18: ...tic alarm is triggered In addition an alarm out put is connected The level and the operating states are displayed both at the device and at the PC Delay times for triggering an alarm can be set both a...

Page 19: ...eased from 1 reading every 15 minutes to 1 reading per minute Thus the progression up to exceeding the limiting temperature is displayed with a higher resolution and is thus more accurately traceable...

Page 20: ...1 to 32 date and time prevailing date and time of an occurred alarm message and information on data connection to the Master M automatic refilling is triggered F device is switched inactive i are indi...

Page 21: ...full on the device When resetting this alarm an existing alarm Memory full is reset If data are not to be saved or no PC is connected this alarm should always be deactivated When the alarm Memory ful...

Page 22: ...cess as soon as one of the connected devices has started a refill process This accelerates for example the cooling of a LIN transfer line and minimizes cooling losses active inactive The devices can...

Page 23: ...is still set to normal operation Re cooling 1 The Re cooling function is available via a service menu in the PC software This service menu can only be accessed by service personnel When the adjustable...

Page 24: ...vice software version in the system The functions and commands used throughout the system are based on this version lowest common denominator The functions of the individual devices are not affect ed...

Page 25: ...put make contact Collective filling With this the function collective filling can be activated via an external switch 5 Change over contact 250 V AC 5 A constant current 2 A Main valve With this a cen...

Page 26: ...and Reserve 2 Alarm Events No Event Default No Event Default Minimum Alarm Vessel is Activ Maximum Alarm Lid is Open Excess Temperature Magnetic Valve Activated Max Lid Opening Time Exceeded Temperatu...

Page 27: ...Solenoid valves opens as long as the key button is being pressed e g for unfogging Function is inactive if max alarm exists Function is inactive if the level probe is defective A AUTO FILL Starts auto...

Page 28: ...e the storage vessel automatically between minimum and maximum At the display of BIOSAFE CONTROL this display can be seen In normal operation the following conditions are given Temperature is displaye...

Page 29: ...E CONTROL 25 Examination per Working Day Daily and generally after starting the computer pro gramme the user is requested to subject the system to a visual examination By this a visual examina tion sh...

Page 30: ...of Accidents Regulation by the Central Office for Safety and Health BGR 500 Chapter 2 33 former BGV B 6 Occupational Safety Regulations For safe operation Do not carry out any mechanical and thermal...

Page 31: ...Safety 27 5 1 Safety Safety advices Handling with cryogenic liquefied gases Source IGV Germany...

Page 32: ...Safety 28...

Page 33: ...Safety 29...

Page 34: ...Safety 30 IGV Safety advice The original is in German language Translations into other languages may be carried out by a qualified translation company...

Page 35: ...n air and spreads on the ground PROTECTIVE EQUIPMENT Safety glasses protective gloves or face protection protective shoes EMERGENCY MEASURES IMMEDIATELY NOTIFY FIRE BRIGADE AND POLICE Stop the motor S...

Page 36: ...fied Gases suffocating Class 2 Figure and Group 3A Figure and Group Number Labelling Designation of the Medium 3A 1977 nitrogen cryogenic liquid Caution Marks No 2 Non combustible and non toxic gas No...

Page 37: ...inside buildings and for shunting inside the laboratory Transport should always by carried out by 2 persons Danger trapping of the fingers CHRONOS 220 420 For the transport of Vessel CHRONOS 220 420...

Page 38: ...ssembly of the Vessel Observe safety instructions Ensure good ventilation Consider place of operation Actuate the locking levers of the castors Only operate the vessel under normal room condi tions ab...

Page 39: ...by Cryotherm Service staff or by personnel trained by the Cryotherm Service staff The fill line consists of 1 Decanting hose DN10 1 5 metres normally insulated 2 90o screwing Proceed as follows durin...

Page 40: ...d valve When connecting the fill line to the vessel or the supply line please observe as follows After connecting the fill line open the ball valve for the LIN withdrawal at the vessel or the supply l...

Page 41: ...all valve to the connecting line Check the connecting line for tightness Adjust the requested filling height by means of the level probe of BIOSAFE CONTROL For this see separate operating manuals of B...

Page 42: ...en minimum and maximum At the display of BIOSAFE CONTROL this display can be seen In normal operation the following conditions are given Temperature is displayed Level is displayed No error message on...

Page 43: ...per Working Day Daily and generally after starting the computer pro gramme the user is requested to subject the system to a visual examination By this a visual examina tion shall be carried out indepe...

Page 44: ...ation of addition al heat into the vessel Prior to storing determine a free position for the sample inside the vessel Slowly open the cover That limits nebulosity and improves the view on the sorting...

Page 45: ...ple room storage shelf and storage frame When cleaning the vessel please observe as follows No temperatures exceeding 80 C Use only detergents compatible with plastics at the cover If necessary test c...

Page 46: ...Accessories 42 510 mm 145 mm 140 mm 85 mm CHRONOS 120 Towers 78202833 and 78202834 140x145 mm Towers 78202835 78202836 85x85 mm 8 Accessories 8 1 1 Sorting System CHRONOS 120...

Page 47: ...Accessories 43 510 mm 166 mm 140 mm 85 mm CHRONOS 120 Towers 78202837 and 78202838 140x166 mm Towers 78202835 and 78202836 85x85 mm 510 mm 165 mm 95 mm CHRONOS 120 Towers 77031511 95 x 165 mm...

Page 48: ...ries 44 510 mm 280 mm 80 mm 85 mm CHRONOS 120 Towers 78202831 80 x 280 mm Towers 78202835 78202836 85x85 mm 510 mm 305 mm 80 mm 85 mm CHRONOS 120 Towers 78202832 80 x 305 mm Towers78202835 78202836 85...

Page 49: ...mm 85 mm 659 mm CHRONOS 220 Towers 78202832 80 x 305 mm and 78202835 78202836 85x85 mm 660 mm 140 mm 166 mm 85 mm 85 mm CHRONOS 220 Towers 78202837 78202838 140x166 mm and 78202835 78202836 85x85 mm 8...

Page 50: ...0 mm 140 mm 145 mm 85 mm 85 mm CHRONOS 220 Towers 78202833 and 78202834 140x145 mm and 78202835 78202836 85x85 mm 660 mm 80 mm 280 mm 85 mm 85 mm CHRONOS 220 Towers 78202831 80 x 280 mm and 78202835 7...

Page 51: ...Accessories 47 660 mm 95 mm 165 mm CHRONOS 220 Towers 77031511 95 x 165 mm...

Page 52: ...Accessories 48 850 mm 85 mm 165 mm 95 mm 85 mm CHRONOS 420 Towers 77031511 95x165 mm and 78202835 78202836 85 x 85 mm 8 1 3 Sorting system CHRONOS 420...

Page 53: ...mm 166 mm 85 mm 85 mm 85 mm CHRONOS 420 Towers 78202837 78202838 140x166 mm and 78202835 78202836 85x85 mm 850 mm 140 mm 145 mm 85 mm 85 mm 85 mm CHRONOS 420 Towers 78202833 78202834 140x145 mm and 7...

Page 54: ...50 mm 80 mm 305 mm 85 mm 85 mm 85 mm CHRONOS 420 Towers 78202832 80 x 305 mm and 78202835 78202836 85x85 mm 850 mm 80 mm 280 mm 85 mm 85 mm 85 mm CHRONOS 420 Towers 78202831 80 x 280 mm and 78202835 7...

Page 55: ...has to be clear and unmistakable by the sorting system and a cor responding labelling It has to be possible to fix the samples in their position The falling out of the sample and the floating out from...

Page 56: ...therm service personnel Skilled personnel specially trained for this medical device by the manufacturer CHRONOS visual examination outer condition stability examination for undue frost formation exami...

Page 57: ...y We recommend a conclude a service contract with Cryotherm GmbH Co KG for the yearly maintenance Additionally to the yearly maintenance the following examinations have to be carried out by the user w...

Page 58: ...Maintenance Repair 54 In case of returning the BIOSAFE 120 220 420 MD or parts the declaration of decontamination must by all means be completed and enclosed 9 2 Declaration of Decontamina tion...

Page 59: ...5 6 220V 50Hz 16 7 W 7 bar 0346709 0346709 0346709 6 Operating instructions BIOSAFE 120 220 420 MD 78203751 78203751 78203751 7 Blind cap 1 4 79404869 79404869 79404869 8 Cryotherm logo 77031446 77031...

Page 60: ...below the storage shelf This reserve guarantees the requested storage temperature of 130 C also with a minimum filling ratio LIN level in storage shelf height for another 4 5 days with BIOSAFE 120 MD...

Page 61: ...ly during and immedi ately after filling Rearrange the samples before putting out of op eration In case of nitrogen escaping there exists the danger of suffocation open windows and doors leave closed...

Page 62: ...he function of the valves See separate op erating manual of BIOSAFE CONTROL Frost formation on the vessel Upper vessel edge thawed This is operational after refilling or cool ing in Vessel is directly...

Page 63: ...ing The cover cannot be opened Possible frost formation at the cover edge can possibly result in the fact that the cover cannot be opened For opening loosen the cover with lat eral movements and moder...

Page 64: ...the device according to the regulations When exchanging parts only original spare parts have to be used Wear parts are not subject to warranty Extent and duration of our warranty comply with the regul...

Page 65: ...Co KG Euteneuen 4 57548 Kirchen Sieg Tel 02741 9585 0 Fax 02741 6900 Cryotherm GmbH Co KG certified according to DIN EN 13485 Article No 78203751 y 1015 Subject to change Cryotherm GmbH Co KG registe...

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