Capintec CRC-712MX Owner'S Manual Download Page 66

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CAPINTEC, INC.

CRC

-712MX

Re-calibration, 1-4
Receiving Condition Examination, 4-1
Repeatability, 2-6
Requirements

Environment, 2-3, 4-3
Power, 2-3, 4-3

Safety, 1-1

Tips, 1-4

Servicing, 7-2
Setup, 4-1
Shielding, 2-4
Shipping, 7-7
Symbol Definitions, 1-1

Technical Description, 2-3
Test

Accuracy, 5-5
Battery, 5-2
Contamination, 5-2, 5-4
Daily, 5-1, 5-3
Geometry, 5-1
Linearity, 5-4

Troubleshooting, 7-4

Unpacking, 4-1

Voltage

High, 1-2
Power Line, 1-1

Well Liner Contamination, 5-4

Zero, 5-1

i - 2

INDEX

January 08

Summary of Contents for CRC-712MX

Page 1: ...msey NJ 07446 Phone 800 ASK 4CRC Fax 201 825 1336 Capintec Inc Service Center 620 Alpha Drive Pittsburgh PA 15238 Phone 800 227 6832 Fax 412 963 0610 Copyright 1992 Capintec Inc CRC is a registered trademark of Capintec Inc U S Patents 3 748 476 and 3 840 745 ALL RIGHTS RESERVED Manual Stock No 9250 0068 Rev C January 2008 ...

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Page 3: ...TING INSTRUCTIONS 3 1 GENERAL 3 1 PANEL DESCRIPTIONS 3 1 Front Panel 3 1 Back Panel 3 4 SYSTEM SETUP 4 1 GENERAL 4 1 RECEIVING CONDITION EXAMINATION 4 1 UNPACKING AND INSTALLATION 4 1 ASSEMBLY 4 2 ENVIRONMENT REQUIREMENTS 4 3 POWER REQUIREMENTS 4 3 Readout 4 3 Printers 4 3 INITIAL TURN ON PROCEDURES 4 4 ACCEPTANCE TESTING 4 4 GENERAL OPERATIONAL SETUP 4 5 Locking the Curie or Becquerel Mode of Ope...

Page 4: ...REVENTATIVE MAINTENANCE 7 2 SERVICING 7 2 LINE VOLTAGE SELECTION FUSE REPLACEMENT 7 2 Readout Fuses 7 2 Printer Fuse 7 3 TROUBLESHOOTING 7 4 Nothing appears on the display 7 4 High background indication 7 4 Indication of significant negative activity 7 4 Printer will not respond 7 4 ACCESSORIES AND REPLACEMENT PARTS 7 5 Environmental Shield 7 5 Positron Shield 7 5 Hot Cell Chamber Mounting Flange ...

Page 5: ...N The CRC 712MX Radioisotope Dose Calibrator consists of the following Readout Unit Chamber s Power Cord Printer optional ELECTROMAGNETIC INTERFERENCE POTENTIAL This equipment generates radio frequency energy and if not installed and used in accordance with the instructions may cause harmful interference to nearby devices However there is no guarantee that interference will not occur in a particul...

Page 6: ...re are basic precautions you must observe to avoid injuring yourself the patient or damaging the equipment Follow the unpacking and assembly instructions document and read this manual carefully before using this equipment Be sure to save all provided documents for future reference Understand all warning and caution labels as explained in CHAPTER 1 SAFETY before operating this equipment ii PREFACE ...

Page 7: ...ed on the back of the Readout Unit is a label Figure 1 1 providing the system power requirements and the replacement fuse values for power line voltages Please reference CHAPTER 7 CLEANING AND MAINTENANCE for instructions on how to change the fuses and line voltage of the CRC 712MX A fire hazard may exist if the wrong size of fuse is installed Figure 1 1 Located on the Power Cord is a label Figure...

Page 8: ...aces on the bottom of the chamber on the 150 Volt Battery pack inside the chamber on the cover of the main power supply in the readout unit and pertains to the electrical safety of the chamber and readout It is necessary because of the high voltage present approximately 150 volts on the Battery board installed in the chamber and the line voltage inside of the readout A screwdriver is necessary to ...

Page 9: ...ed sensitivity the wall of the ionization chamber is extremely thin and the chamber is filled with pressurized gas It is therefore essential to avoid mechanical shock or vibration of any kind CAUTION When working with a heavy sample especially a CapMac or Moly Assay Canister always lower it gently into the chamber well Dropping any heavy object into the well can cause permanent expensive damage CA...

Page 10: ... Center to guarantee that the instrument s high reliability is maintained GENERAL SAFETY TIPS Unplug the equipment before cleaning it Use only a damp cloth do not use solvents or aerosol cleaners To protect the equipment from overheating do not use the equipment directly in front of a radiator or heat register Do not use the equipment near water or spill liquids of any kind into the equipment Be s...

Page 11: ... in conjunction with a one atmosphere ionization chamber possessing extremely high sensitivity and stability Curie or Becquerel units of measurement are selected by a rotary switch that can be locked in either position An 8 button measurement range switch provides unambiguous manual selection or automatic selection of 6 activity measurement ranges Manual range selection provides the shortest measu...

Page 12: ...ameter and 25cm deep Ionization Chamber well allows convenient measurements of virtually any radioisotope in clinical use including whole generators Critical positioning of the sample vial or corrections for container effects should not be required except for X ray low energy γ ray or high energy β ray emission dominant radioisotopes The external shield of the Ionization Chamber protects users fro...

Page 13: ...0 C and the maximum relative humidity is 90 non condensing to warrant maximum reliability and accuracy The instrument should be located where the barometric pressure is within a range of 27 31 inches of mercury 91 105 kilopascals Storage The instrument should be stored where the temperature is stable and the range is from 40 F to 115 F 4 C to 43 C and the maximum relative humidity is 90 non conden...

Page 14: ...bles supplied with the instrument On Off Switch The on off power switch I on c off is located on the back of the instrument Dimensions Readout Height 15cm 6in Width 32cm 12 5in Depth 46cm 18in Weight 6 8kg 15lb Remote Chamber Height 41 9cm 16 5in Diameter 17 2cm 6 76in Weight 13 6kg 30lb Well Diameter 6 1cm 2 4in Well Depth 25 4cm 10 0in Cable Length 1 8m 6ft Cables Power 1 8m 6ft Shielding High D...

Page 15: ...certainty of 1 count on the least significant digit The units of measurement are displayed as back lighted measurement characters after the numeric display Iometer Low Input Impedance Electrometer Accuracy 3 of reading Response time 90 of full scale reading within 2 seconds for activity measurements of 20 millicuries 2000GBq or more Noise RMS measurement fluctuations 2 counts in the last digit for...

Page 16: ...accuracy of the calibrator is determined by the accuracy of specific source calibration chamber linearity and response iometer digital readout Repeatability Measurements will repeat to within 1 for a period of 24 hours during which time the instrument is maintained under constant temperature humidity and background radiation conditions and is powered at all times Fig 2 1 CRC 712MX Simplified Block...

Page 17: ...ic display and unit indicators The placement of the decimal point and illumination of the proper units is done automatically Blinking digits indicates an activity above the warning level Reference CHAPTER 2 FUNCTIONAL TECHNICAL DESCRIPTION SECTION PERFORMANCE DIGITAL READOUT B TEST Push Button When this button is pressed the Ionization Chamber bias battery voltage is displayed The reading should b...

Page 18: ...tton depressed and the locking ring rotated counter clockwise G Calibration for Other Isotopes To obtain a readout of any isotope set this precision potentiometer to the calibration number for that isotope obtained from the Calibration Card or the table in Appendix II and press the OTHER push button H Calibration Card A list of calibration numbers for commonly used isotopes Reference Appendix II f...

Page 19: ...CAPINTEC INC CRC 712MX Figure 3 1 CRC 712MX Front Panel January 08 GENERAL OPERATING INSTRUCTIONS 3 3 ...

Page 20: ... for 220 Volt power line operation Line Voltage Selector Must be set to indicate the correct power line voltage Locking Screw Storage The Curie Becquerel selector switch may be locked in either position to comply with local hospital operating procedures This Screw is used to lock the selector switch in either position Remote Chamber Connector s The CRC 712M Model is provided with connectors for 5 ...

Page 21: ...CAPINTEC INC CRC 712MX Figure 3 2 CRC 712MX Back Panel January 08 GENERAL OPERATING INSTRUCTIONS 3 5 ...

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Page 23: ...to help obtain restitution from the carrier UNPACKING AND INSTALLATION The instrument is packed and shipped as a complete unit All the accessories and options are contained in their appropriate cartons Optional equipment is shipped in separate cartons The instrument is shipped in a plastic bag in order to provide a dry and clean environment during shipment Remove all outer packing material and tap...

Page 24: ...t and the printer are in the OFF or 0 position 2 Connect the Chamber Cable s to the connector s at the rear of the CRC 712MX Readout labeled IONIZATION CHAMBER 3 Attach the printer cable to the PRINTER Port connector at the rear of the CRC 712MX Readout Attach the other end to the Epson or Okidata printer 4 For each printer type verify that the correct paper is installed 5 Attach the Power Cables ...

Page 25: ...hese environmental requirements are not followed the instrument may display erroneous readings POWER REQUIREMENTS CAUTION If the input voltage to the following items is not within the stated limits the unit may not function correctly or may be damaged Readout Line Voltage Rear Panel Selectable 90 130 VAC Nominal 115 VAC 50 60Hz 0 11A or 180 260 VAC Nominal 230 VAC 50 60Hz 0 06A Note For 230 volt a...

Page 26: ...ent data is printed on the installed printer 9 With a computer connected start the communication program that is loaded on the computer a Select the VT 100 HyperTerminal or other generic terminal emulation program b Use the SETUP menu to select the COM Port 1 or 2 9600 Baud Rate 1 Stop Bit NO Parity Bit and 8 Data Bits c Start the terminal emulation program on the computer d Set the CAPS LOCK key ...

Page 27: ...elector switch on the front panel of the instrument This feature is particularly useful when a country is changing from the older unit of measurement the Curies to the currently recognized unit of measurement the Becquerels When this transition is complete it may be desirable to permanently lock the selector switch in the Becquerel mode 1 Facing the rear of the calibrator locate the Unit s Selecto...

Page 28: ... of substantial activity enough to display 100µCi 3 7MBq or higher if possible 0 5mCi 18 5MBq or higher into the calibrator well 4 Record the activity displayed including the decimal point and the units 5 Remove the push button being re assigned by gripping it with pliers and pulling straight out 6 Activate the switch being re assigned by pressing the white fingers that held the button with a scre...

Page 29: ...CAPINTEC INC CRC 712MX Figure 4 3 January 08 SYSTEM SETUP 4 7 ...

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Page 31: ...aily Tests The Daily Tests should be conducted at the beginning of each working day prior to measuring any samples which will be administered to patients These tests consist of a Zero Adjustment a Background Adjustment an Instrument Functioning Test a Contamination Test and a Reference Source Test Zero Adjustment This procedure should be performed at least once every day the instrument is used The...

Page 32: ...e battery voltage for each chamber 3 Record the display reading The reading should be constant to within 2 volts and never vary more than 5 volts from one day to the next under constant operating conditions When the voltage decreases to below 140 volts the battery should be replaced Contamination Test Sample Holder 1 Remove the sample holder from the well 2 Perform the Background Adjustment proced...

Page 33: ...ure All readings should be consistent with previous readings to within 2 If a Cs137 Source is used as a Reference the reading will decrease by 0 2 per month Quarterly Tests The Quarterly Tests consist of Daily Test Checking Preset Calibration Well Liner Contamination Linearity Test Daily Tests The normal Daily Tests as described above should be performed as a part of the Quarterly Tests Checking P...

Page 34: ...surements of the same sample as it decays Continue until the activity is below the minimum assayed in normal use CAUTION Initially the activity of the Mo99 contamination in the sample will be insignificant compared to the activity of the Tc99m However Mo99 has a much longer half life than Tc99m If the test is continued down to very low levels the activity of the Mo99 may become significant by the ...

Page 35: ...imately those levels normally encountered The activity determined by the calibrator should coincide with the activity of the certified Reference Standard Source to within 5 Should the activity reading for Co60 and or Co57 be confirmed to be inaccurate by more than 5 the instrument should be repaired Do not alter the system calibrations of the instrument unless the cause of the disagreement is foun...

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Page 37: ... used isotopes As the user requirements are different for each nuclear medicine facility the procedure to re assign these preset buttons for other radioisotopes is provided in CHAPTER 4 SYSTEM SETUP SECTION REASSIGNMENT OF A PRESET PUSH BUTTON To measure the activity of one of these 8 preset radioisotopes 1 Verify that the Zero and Background adjustments of the calibrator are within the specified ...

Page 38: ...t measurement If numerous measurements are being made in the same activity range select the specified range for the faster measurements 5 Insert the sample to be measured into the Ionization Chamber well by means of the plastic Sample Holder dipper 6 Observe that the display stabilizes and that the correct units are indicated 7 Record the activity measurement on the appropriate form or press the P...

Page 39: ...DMINISTRATION ADDITIONAL CALIBRATION NUMBERS Radioisotopes other than those whose calibration numbers are supplied by Capintec may also be measured by the calibrator New calibration numbers may be derived by either direct calibration with Standard Reference Sources or by intercomparison of activity measurements using a standard 12 atmosphere CRC Calibrator Direct Calibration with Certified Standar...

Page 40: ...he owner s manual for a standard CRC Calibrator 4 Record the displayed activity for the measured source 5 Place the SAME source in the CRC 712MX chamber 6 Select the OTHER push button and adjust the Calibration Control to obtain the same displayed activity as was recorded in step 4 7 Record the number appearing on the Calibration Control knob dial This number may now be used for all future measure...

Page 41: ... s high reliability is maintained Contact Capintec s Authorized Service Center in Pittsburgh for servicing or re calibration at 1 800 227 6832 CLEANING INSTRUCTIONS WARNING TO AVOID ELECTRICAL SHOCK OR DAMAGING OF THE CRC 712MX NEVER GET WATER OR LIQUIDS INSIDE THE CHAMBER OR THE READOUT ENCLOSURE DO NOT USE AN AEROSOL DISPENSER TO SPRAY THE EQUIPMENT WITH ANY CLEANING SOLUTION OR LIQUID TO AVOID ...

Page 42: ...m In this event please contact Capintec for further assistance The Quality Assurance tests should be immediately performed if The equipment has been subjected to extreme physical stress Liquids enter the readout unit and or chamber or Any cable shows signs of damage SERVICING The system is covered by a one year limited warranty under normal conditions of use Other than the Readout Unit fuses see L...

Page 43: ...cified for the selected line voltage and slide the clear plastic door to the right a For the 115 volt power line use a 1 4 Amp slow blow type fuse b For the 230 volt power line use a 1 8 Amp slow blow type fuse 7 Install a power cord that is specified for the selected line voltage a For the 115 volt power line use a detachable power cord with a NEMA type 5 15R 3 prong plug similar to Belden 17250 ...

Page 44: ...NT High background indication Chamber Well liner or dipper may have become contaminated See CHAPTER 5 QUALITY ASSURANCE ACCEPTANCE TESTING SECTION CONTAMINATION TEST Background may actually be high Check by removing the dipper and placing a lead sheet over the top of the well Indication of significant negative activity Zero setting or Background level may have changed Perform the Daily Test See CH...

Page 45: ... 0017 Epson Roll Printer and cable 5430 0058 Printer Ribbons CALL Additional copies of Owner s Manual 9250 0050 Replacement 150 volt lithium battery 0500 2019 Note Circuit diagrams component parts lists descriptions and calibration instructions are available to appropriately qualified personnel Environmental Shield A set of eight 4 1 cm 1 7 in thick lead rings that surround the chamber and reduce ...

Page 46: ...dard RS 232C communication port The measurement data can be had in 4 different formats and used as needed for different programming applications As examples the calibrator data can be used for dose computation or isotope inventory control This option consists of a calibrator internal cable an interface PC board and a demonstration program disk Calicheck A kit of 7 attenuating sleeves designed to p...

Page 47: ...tipulating the maximum environmental conditions for safe storage and shipment Figure 7 2 Figure 7 3 In order to ship this product all appropriate Department of Transportation DOT and if shipped by air the International Aviation and Transportation Administration IATA requirements for the shipment of the pressurized 12 Atmosphere Ionization Chamber Detector must be met January 08 CLEANING AND MAINTE...

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Page 49: ...ty in time interval dt dt dN A The special unit of activity is Curie Ci 1 Ci 3 7 x 1010 s 1 exactly Note The term nuclear transformation is meant to designate a change of nuclide of an isomeric transition ICRU REPORT 19 1971 The SI International System of Units unit for activity is the reciprocal second s 1 and is named the Becquerel Bq i e 1 Bq 1 Nuclear Transformation per second 1 Ci 3 7 x 1010 ...

Page 50: ...ons α Particle Radiation The most energetic α particle emitted by a radionuclide has an energy of less than 10 MeV which corresponds to a range of about 10 mg cm2 8 cm in air Because of its short range an α particle from a radionuclide cannot penetrate to the Ionization Chamber s sensitive volume and therefore cannot be detected All α decays however are accompanied by photon radiation as the daugh...

Page 51: ... vacancy in the atomic orbital shell resulting in x rays as the atom de excites The energy of k x ray is approximately 100 2 Z Ek keV where Z is the atomic number of the daughter nucleus γ rays are also often given off as the daughter nucleus de excites Photon Radiation Photon radiation is associated with most nuclear transformations A high energy photon interacts with matter very weakly Photon in...

Page 52: ...se mechanisms are Photoelectric effect Compton effect and pair production The energy of the photon determines which process or processes is possible Photoelectric Effect The photoelectric effect is an interaction between a photon and an electron that is bound to an atom In the photoelectric process the photon is absorbed by the atom and a bound electron is ejected The kinetic energy of the ejected...

Page 53: ...on and a positron appear A positron is a particle with the same properties as an electron except that it has a positive charge In order to produce an electron positron pair the incident photon must have an energy of at least twice the mass of an electron i e 1 022 MeV This process dominates for very high energies that is above about 10 MeV The number of pair production interactions per unit mass i...

Page 54: ...M of Activity Certified Co60 SRM to due Output Detector A Sample of Activity A Sample to due Output Detector RA 1 The sensitivity of the detector for a photon of energy Ei is defined as 60 Co of Curie one to due Output Dtector E of Photons 10 3 7 to due Output Detector i 10 i S 2 The detector response and the sensitivity have the following relation 3 i i i S I i R Where Ii is the intensity of the ...

Page 55: ...ontainer for all radioactivity measurements The plastic syringe is convenient since it represents the delivery vehicle to the patient in most clinical situations Significant errors will occur in some instances e g if the radioisotope is assayed in an appreciably different material and or wall thickness than that of the standards The ampoules of recently available standards from NIST are uniform Pl...

Page 56: ... the instrument unless the effect of impurities is eliminated by photon filtration as is done with Mo99 breakthrough in Tc99m However the presence of low level radionuclide impurity does not negate the usefulness of a radioisotope calibrator if the user is aware of its presence and has an independently determined calibration including photons arising from the impurities A1 8 APPENDIX I January 08 ...

Page 57: ...asured the reading will be lower than the true activity in the needle due to the shielding effects filtration of the needle To estimate the true activity in a needle increase the reading obtained with a calibration number for Ra226 790 by 2 for each 0 1mm of platinum wall thickness For example add 10 to the reading for a 0 5mm wall platinum needle and add 20 to the reading for a 1 0mm wall platinu...

Page 58: ...ubstantial It could be about 3 to 5 times that for a syringe If no value is given in this column the correction is not significant except for a container differing greatly from the standard ampoule e g Very thick glass container vial made of glass which contains lead etc UNCERTAINTY DUE TO PUBLISHED DATA This is the uncertainty on the value of the activity From calibration numbers calculated from ...

Page 59: ...o 58 A HANDBOOK OF RADIOACTIVITY MEASUREMENTS PROCEDURE K S Associates Inc Accredited Dosimetry Calibration Laboratory TABLE I CAL CARD CRC _______ Serial No _________ Tested ___ ___ ___ By ____ Isotopes Cal Setting Isotopes Cal Setting Co 57 112 I 131 201 Co 60 990 Ba 133 555 Ga 67 113 Xe 133 194 Mo 99 Cs 137 260 Tc 99m 96 Tl 201 160 In 111 313 Ra 226 790 I 123 286 These Cal Settings apply to the...

Page 60: ...of the overall accuracy of an assay See previous sections of this manual for a discussion of some of the conditions under which the calibration numbers are valid Uncertainty Due To Radioisotopes Calibration Setting Number Syringe Corr Published Data Half Life NCRP 58 Ref Comments Co57 Cobalt 112 1 9 271 7 D 2 NIST91 Co60 Cobalt 990 1 0 5 2714 Y 5 NIST90 Ga67 Gallium 113 1 4 3 261 D 1 NBS78 INTERCO...

Page 61: ... Calibration Number 1 Cs137 20mm x 33mm dia st steel 3M Tube 6502 6D6C NIST uncertainty 2 0 3275 2 I125 4 5mm x 0 8mm dia 3M 6702 resin bead NIST uncertainty 5 0 145 3 I125 4 5mm x 0 8mm dia 3M 6711 silver wire NIST uncertainty 6 0 145 4 Ir192 3mm x 0 5mm dia st steel Best Industries Seed in ribbon NIST uncertainty 2 0 4596 5 HDR Ir192 4mm x 1 1mm dia st steel Nucletron Mallinckrodt ISO C53211 Wel...

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Page 63: ...t is the elapsed time after the pure parent isotope was produced and F is the decay branching ratio The chamber response R may be obtained from the calibration number N using the following equation 0797 0 1075 8 N R When the half life of the parent nucleus TA is much shorter than that of the daughter nucleus TR the parent decays down to the daughter After about 10 TA we can assume that only the da...

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Page 65: ...se 6 2 Sleeve Method 5 4 Assembly 4 2 M B Maintenance Background 5 2 Preventive 7 2 C Measurement Other Isotope 6 2 Checking Preset Calibration 5 3 Pre Measurement Procedures 6 1 Circuit Protection 2 4 Preset Isotope 6 1 Cleaning 7 1 Printing 6 4 Contamination Mode of Operation 4 5 Well Liner 5 4 Contamination Test 5 2 5 4 O D Overall Accuracy 2 6 Daily Tests 5 1 5 3 P Detector 2 5 Panel Descripti...

Page 66: ... Safety 1 1 Tips 1 4 Servicing 7 2 Setup 4 1 Shielding 2 4 Shipping 7 7 Symbol Definitions 1 1 T Technical Description 2 3 Test Accuracy 5 5 Battery 5 2 Contamination 5 2 5 4 Daily 5 1 5 3 Geometry 5 1 Linearity 5 4 Troubleshooting 7 4 U Unpacking 4 1 V Voltage High 1 2 Power Line 1 1 W Well Liner Contamination 5 4 Z Zero 5 1 i 2 INDEX January 08 ...

Page 67: ...implied warranties and we make no warranty that the products sold herein are merchantable or are suitable for any particular purpose The benefits of this warranty shall extend only to the buyer and to none other We shall have no liability of any nature arising out of the use or application of the product in conformity with this warranty If the product shall fail to perform in conformity with the w...

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