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Sophisticated Life Science Research Instrumentation

Specifications subject to change without notice

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Содержание PhenoMaster

Страница 1: ...www TSE Systems com PhenoMaster Hardware Operating Instructions Core Modules Sophisticated Life Science Research Instrumentation Info TSE Systems com ...

Страница 2: ...d subject to due penalty at law This applies in particular to their reproduction processing translation microfilming as well as to their storage and processing in electronic systems This regulation does not apply to reproductions for internal use Further examples of these operating instructions are available and can be ordered from us a charge will be made for these extra copies PM15_HW_CoreModule...

Страница 3: ...21 4 1 Malware Scanner 21 4 1 1 Whitelist 22 4 1 1 1 System Software 22 5 Installation Drivers Interface Software 23 5 1 Interface Driver 23 5 2 Interface Installation 25 5 3 System Software 26 5 3 1 Creating a Short Cut 26 5 4 Windows Settings 26 5 4 1 Power Options Properties 26 5 4 2 Disabling Parameter Automatically adjust clock for daylight saving changes 27 6 Connecting Devices General 29 7 ...

Страница 4: ...Calorimetry result parameters 6 Fig 3 Hardware layout Rod nipple 14 Fig 4 Positioning of O ring valve rod 14 Fig 5 Reference Hardware module 20 Fig 6 PCI slot PC mainboard 26 Fig 7 Date and Time tab Windows7 27 Fig 8 Time Zone Settings Windows7 28 Fig 9 Cage lid holder w inserted lid 30 info TSE Systems com www TSE Systems com ...

Страница 5: ...ty of the animal in the animal cage Special frames are equipped with IR sensors each sensor consists of an IR receiver and the corresponding IR emitter which produces infrared light beams intersecting in the animal cage The frames can be supplied with light beams in the X Y and Z level according to the system configuration Various parameters can be used for determining the locomotor activity of th...

Страница 6: ...ns that the operator can assemble the required parameters both in the Table and in the Graph display print them out or export them as a csv file that can be read e g into spreadsheet or database software This is possible both online with the running data file and also offline Calorimetry Result Parameters Parameter Description Unit Remarks Flow Flow l min Temp Temperature C Measurement in the box ...

Страница 7: ...the amounts of liquid and feed removed will be registered Measured values that lie outside these limits e g those caused by knocking the dispenser against the sensor or by the animal lifting the dispenser will not be taken into account Activity measurements via InfraMot sensors can be done for rapidly and easily determining the gross activity of mice rats and other small laboratory animals via an ...

Страница 8: ...operating instructions are subject to change without further notice These instructions or parts of these instructions should only be translated into other languages by a qualified technical translator TSE Systems should be informed about this in advance TSE Systems cannot be made responsible for a faulty translation Liability claims resulting from a faulty translation are to be made against those ...

Страница 9: ...ly trained and authorized expert personnel Test run We recommend to perform a test run before the system is used for the first time in order to familiarize yourself with its operation and to make the necessary settings for the particular series of experiments 2 4 Explanation of Symbols Warnings Safety Messages and Symbols 2 4 1 The following section contains information about the use of the safety...

Страница 10: ...of the hazard follows Instructions with Dos and Don ts In this case a warning is associated with operating steps that follow or Instructions with Dos and Don ts Instructions with Dos and Don ts WARNING Here the description of the hazard follows Instructions with Dos and Don ts In this case a warning is associated with the particular operating step that precedes it Notice Notice is used to address ...

Страница 11: ... the latest and replaced as necessary Conformity 2 4 3 This product and its accessories conform to the requirements of the Low Voltage Guideline 73 23 EEC as well as the EMC Directive 89 336 EEC and are accordingly marked with the CE symbol For conformity with the standard it is essential that the details in the instructions are strictly observed during operation 2 5 General Safety Instructions Pr...

Страница 12: ...epending on their specification intended to register the activity in the X Y or Z direction only They should not be interchanged and should be mounted in accordance with these instructions The system isn t intended to register distances covered for determining the exact location of the animal The sensors for measuring the activity should be free from contamination and the beam path should not be h...

Страница 13: ...ment should be the same as for the calibration process For better comparability of test data the room conditions particularly temperature and humidity should be kept as constant as possible Air pumps push principle respirometry overpressure principle o The pump is designed for pumping air only The performance values can be found on the pump label o Ensure that the operating air temperature is with...

Страница 14: ...eceiver 3 Valve rod 4 Gasket 5 O ring rubber valve rod 6 Pressure spring 7 Extension cap o Position O ring valve rod onto gasket shorter end of valve rod The smaller base of the O ring must be orientated towards the gasket as otherwise flow through the opening of the extension cap is always blocked and animals can die of thirst Correct Incorrect Fig 4 Positioning of O ring valve rod 3 2 5 6 1 7 4 ...

Страница 15: ...ns only as otherwise inaccurate results will be obtained If calorimetry measurements are to be made without the presence of the drinking dispensers feeding dispensers the corresponding openings should be closed off Sensors The sensors are intended to register the specified measured values only and are to be used for this purpose only For proper use the calorimetry and the drinking feeding body wei...

Страница 16: ...e operated in locations only which satisfy the following ambient conditions Setup in a closed room Fresh air supply required Dry location don t store liquids above the system devices Keep all surfaces e g floors dry Protect against water splashes Solid level and nonflammable support The ambient temperature must be 15 C 59 F and 25 C 77 F The animal cages alone can be placed in a climate chamber wi...

Страница 17: ...s and that persons don t enter or leave the room frequently 2 8 Setting up System The support surfaces for the cages must ensure vibration free operation as otherwise the sensitive measurement technique could be negatively affected If shelving systems are used for setting up the cages you should ensure that they are not located beneath the illumination or in front of an air conditioning inlet as o...

Страница 18: ...sings and not by their cables Drinking and feeding dispensers must not be attached at the sensor hooks The sensor frames should be transported only in a dismantled condition in order to avoid distortion of the individual devices by shearing forces 2 10 Disposal Discarded devices or worn device components contain reusable material Recycling All the components of the device can be disposed of in acc...

Страница 19: ...al cages per Calorimetry Control Unit Each cage is continuously provided with fresh air from an air pump via the Control Unit For a 16 place system one Master Control Unit and one Slave Unit are required which each have eight connections for the air supply to the cages and the temperature sensors The Master Control Unit also contains the standard sensors for O2 and CO2 measurement in addition to t...

Страница 20: ...s the counter totals during a measuring interval This measuring data provides a relative measure of the duration and intensity of the activity This allows general statements about the activity of the animal to be made Activity measurements via running wheels can measure the spontaneous activity of the animal e g in a home cage The animal itself sets the running wheel in motion voluntary running wh...

Страница 21: ...PC memory If you use antivirus software observe instructions in Section 4 1 In the BIOS settings of the PC all options that allow PC to step down CPU clock to save energy should be disabled If a dialog with the message Error within Query Performance functions please restart switch off PC If this returns disable EIST CIE processor feature in BIOS pops up check BIOS settings of the PC NOTICE Instrum...

Страница 22: ...luded from virus scans 4 1 1 1 System Software Directories C Documents and Settings All Users Application Data TSE PhenoMaster C ProgramData TSE PhenoMaster C Program Files TSE PhenoMaster C Program Files x86 TSE PhenoMaster Files Analyse set CalibrLogFile log GasMeasCalibrData set log txt PhenoMaster cal PhenoMaster set Threadlog log AlySet bin dat evt par tim _ACT raw _CALO bin _DFT bin _EVENTS ...

Страница 23: ...tware Without prior consulting your system administrator AND TSE do NOT alter BIOS settings of PC 5 1 Interface Driver Drivers PCIS DASK are designed for Windows7 Windows10 Supplied on DVD Installation sequence First install driver then install hardware Number of drivers required With PCI interfaces from ADLINKTech it is sufficient to install a single appropriate driver for ALL interfaces Driver v...

Страница 24: ...uctions Enter name and organization and press Next Press Next to confirm the default destination directory Without prior consulting TSE Service the default destination directory should not be altered info TSE Systems com www TSE Systems com ...

Страница 25: ...gs On InstallShield Wizard Completed dialog press Finish Press Yes to reboot the PC Shut down Windows again and power OFF PC Proceed to interface installation see Section 5 6 5 2 Interface Installation NOTICE Instrument damage Static electricity or touching the circuitry can damage the interface info TSE Systems com www TSE Systems com ...

Страница 26: ...pin connection leading from the interface board Ensure that the PC is powered OFF Disconnect all peripheral devices from the PC Open the PC housing Insert the interface s into a free PCI slot Reclose the housing and secure the slot bracket of the interface with retaining screws Connect monitor mouse and keyboard with the PC Power ON the PC 5 3 System Software See Software Operating Instructions Co...

Страница 27: ...in time Don t use a screensaver Disabling Parameter Automatically adjust clock for daylight saving changes 5 4 2 Some regions have the daylight saving time If so the parameter Automatically adjust clock for daylight saving changes has to be deactivated in order to prevent running experiments to be shut down when the adjustment occurs Windows7 o With the right mouse key click on the time display on...

Страница 28: ...28 PhenoMaster Hardware Operating Instructions Fig 8 Time Zone Settings Windows7 o Uncheck Automatically adjust clock for Daylight Saving Time o Press OK info TSE Systems com www TSE Systems com ...

Страница 29: ...ables so that they cannot be mixed up and cannot trip people up For error free operation all cable connections should be properly secured either by screwing the actual connector or the fixing screws as otherwise measuring errors could occur or data transmission could be interrupted Before carrying out a new test system devices must be freed from all residues of the previous test Place the animal c...

Страница 30: ... a secure stand and simple operation the system cages can be placed in a rack specially designed for them A holder is provided for every calorimetry cage to take its lid when it is removed from the cage Fig 9 Cage lid holder w inserted lid info TSE Systems com www TSE Systems com ...

Страница 31: ...measured values Export functions are used to prepare the data so that user specific analysis is possible The system software is arranged modularly i e depending on the system configuration the software functions that are necessary are enabled only Functions that are disabled are either shown in gray or they are concealed For further instructions see Software Operating Instructions info TSE Systems...

Страница 32: ...ardware during an experiment Switch OFF the monitor during a trial so that adjacent cages are not illuminated during the dark phase Removal of residues After each test suitable measures must be taken to ensure that no residues remain in the system that could falsify the results of subsequent tests We recommend that animals are allowed to habituate with test cages before the tests e g in special tr...

Страница 33: ...oy the sensitive measuring and control equipment Do NOT use dusty animal litter Proceed as follows during start up Three hours prior to the test power ON electronic devices o Start PC o Start software o Power ON Control Unit Weigh the animals and insert them into their animal cages NOTICE Instrument damage If animals are kept in sealed cages without a supply of fresh air for a long time they may b...

Страница 34: ... the system software The easiest way to refill food is to use a small scoop to fill it into the basket attached to the sensor Care should be taken that the pieces of food are large enough so that they don t fall through the basket mesh Activity measurements via InfraMot sensors The InfraMot sensor must NOT be used where it is subject to the effects of heating cooling or ventilation devices Closed ...

Страница 35: ...an dissolve plastic and render it useless Do NOT clean the device and in particular its plastic components with solvents containing hydrocarbons or alcohol unless they are approved as a disinfection method for the particular component If damage has occurred detergents or decontaminants could penetrate the devices and damage them irreversibly Please contact TSE Service If you return contaminated sy...

Страница 36: ...al prior to sterilization this may reduce lifetime of devices The operator has to take additional material properties e g coefficient of expansion into consideration Different material properties during heating may exclude such a device from sterilization as otherwise fractures in the material could occur Taking only individual material properties into consideration is NOT sufficient TSE isn t res...

Страница 37: ...ot specified Not specified 10 2 1 2 Metallic Cage Lid Metallic cage lids should be wiped off if required with a moistened soft lint free cloth or tissue to remove any adhering dirt A stainless steel cleaning agent can also be used to remove any stubborn dirt Detergent residues should then be wiped off The metallic cage lids of the home cages without sensors and dispensers must be decontaminated wi...

Страница 38: ...ty will be reduced due to the increasing chemical degradation to a level which isn t sufficient for miscellaneous applications Applicable sterilization procedures use undiluted ETO as well as mixings including carbon dioxide or inert gas 10 20 ETO 90 80 other gas Sterilization temperature 65 C 149 F With increasing number of sterilization procedures a slight embrittlement associated with fissuring...

Страница 39: ... for cleaning of the Process Control Units Never use disinfectant sprays NOTICE Instrument damage Sensors can be damaged by contact with H2O2 Units with gas sensors e g O2 CO2 must have their test air inlets and outlets sealed 10 4 Cable Organic solvents must not be used for cleaning purposes Avoid the use of cleaning sprays spray disinfectants or strong detergents as they could damage the cables ...

Страница 40: ...40 PhenoMaster Hardware Operating Instructions Appendix A Example configurations Home cage configuration 10 7 8 2 12 6 info TSE Systems com www TSE Systems com ...

Страница 41: ...dules 41 Calorimetry cage w 2x Access Control 1x Drink 1x Feed 1x Body Weight Calorimetry cage w 1x Access Control 1x Drink 1x Feed 1x Body Weight w o sensor 9 10 5 7 4 info TSE Systems com www TSE Systems com ...

Страница 42: ...orimetry cage lid 3 Assembly group swivel mount 4 Assembly group Access Control dummy 5 Assembly group blind adapter 6 Assembly group hood 7 Assembly group Access Control 8 Assembly group blind adapter 9 Assembly group blind adapter w suspension 10 Assembly group sensor housing mouse 11 Knurled screw M3x8 stainless steel 12 Home Cage 3 1 10 7 11 info TSE Systems com www TSE Systems com ...

Страница 43: ...dules 43 B Cage body specifications Type II Floor area cm2 501 Overall dimension W x D x H 391 x 199 x 160mm 15 39 x 7 83 x 6 3inch Plastic Type H Temp Polysulfone PSU info TSE Systems com www TSE Systems com ...

Страница 44: ...Fax 49 0 6172 789 500 Toll free Phone 1 866 466 8873 USA CDN E Mail Info TSE Systems com Toll free Fax 1 866 467 8873 USA CDN www TSE Systems com E Mail Info TSE Systems com www TSE Systems com China TSE Systems China Ltd Rm 1802 No 4 Building Dayin Mingzuo JiaoDaDongLu No 60 Haidian District Beijing 100044 China Phone 86 10 6224 5391 Fax 86 10 6224 2196 Cell 86 137 0123 8855 E Mail China TSE Syst...

Страница 45: ...Core Modules 45 info TSE Systems com www TSE Systems com ...

Страница 46: ...stems com Sophisticated Life Science Research Instrumentation Specifications subject to change without notice Copyright 2017 TSE Systems International Group All rights reserved https www tse systems com support technical support form ...

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