9
10545100-Australia Rev.
– 08/2018
SIDE EFFECTS & CONTRAINDICATIONS
Note:
This is not an exhaustive list. The list was prepared from published articles.
Possible Side Effects of Nitrous Oxide
– Oxygen Conscious Sedation:
May experience nausea, vomiting,
excessive sweating, euphoria, excitement, deep sedation, drowsiness, sleep, dizziness, lightheadedness, dysphoria,
amnesia, and headaches.
Precautions and Contraindications for Nitrous Oxide Use
Precautions/Relative Contraindications
Discontinue the Nitrous Oxide delivery if observed: prolonged inspirations, irregular breathing, involuntary
eye movements, swallowing or gagging, dilated pupils and rigid muscles.”
Side effects (e.g., nausea, vomiting, dizziness, dysphoria, etc.)
Current vitamin B
12
deficiency.
Bronchoconstrictive disease (asthma)
– (at determination of medical professional).
The use with pediatric patients, especially age 1 to 4 years, requires caution and specific protocols
developed by the medical professional; upper age limit at determination of medical professional. Weight
limitations at the determination of medical professional.
Nitrous oxide, although not specifically contraindicated, may pose risks in pregnancy, and should be used
only after consultation with a patient's physician, gynecologist or obstetrician
Contraindications
Inability to hold own face mask, impaired oxygenation, or hemodynamic instability
Acute drug or alcohol intoxication or impaired consciousness (head injury, endocrine or metabolic disease,
patients taking antidepressant or psychotropic drugs), psychologic impairment, patient who has taken
medication to induce sleep.
Decompression injuries, increased intracranial pressure, increased intraocular pressure, intraocular
surgery, bowel obstruction, middle ear surgery, emphysema, pulmonary hypertension.
Current upper respiratory tract infection, chronic obstructive pulmonary disease (COPD), cystic fibrosis,
shock, acute pulmonary edema (APE), pneumothorax, and major chest or maxillofacial trauma, bleomycin
therapy, recent pneumoencephalography
