Crystalline active ingredients
In order to avoid complex postprocessing (e.g. w/ ointment mill), we recommend pulverizing
active crystalline agents with the help of a mortar prior adding to the UNGUATOR® Jar.
Should a solvent for the active crystalline ingredient be part of the formulation, the
ingredients may then also be dissolved in the UNGUATOR® Jar while mixing, e.g. urea in
water. Then the remaining formulation ingredients can be added. Crystalline substances
may also dissolve during the mixing process if the solvent is an ingredient of the ointment
base.
Components to be melt
Components that have been weigh out to fuse may be placed inside an UNGUATOR® jar
,douse with heated aqueous or oily phases of you formualtion constituents (≤ 85 °C/185°F)
to melt the content in full.
In case this process does not sufficiently melt all constituents, the formulation inside
an UNGUATOR® jar might be heated in a warm water bath (≤ 85°C/185°F) or carefully
observed in a microwave oven. In order to ovoid overpressure, please mind having the
white cap on the lid removed.
Formulations without water containing components may be melted already directly inside
the UNGUATOR® Jar by placing the jar in a warm water bath.
Please be aware that UNGUATOR® MB’s must
not
go in the microwave oven! Furthermore,
due to irregular mixing of adipose- and water phases, reaching the melting point might
happen with a delay, since only aqueous parts can be heated in a microwave oven.
Please urgently mind the operation manual of your microwave oven! An excessive
temperature rise for both UNGUATOR® jar and its content must be avoided at all times!
The cooling time and hence the cooling interval decreased in the refrigerator or by using a
cooling jacket/pad. The UNGUATOR® MB should remain in the UNGUATOR® jar during the
cooling phase.
Thermolabile substances
Active ingredients or substances with thermolabile characteristics should be handled with
caution. To protect the substances, we recommend a maximum 1500rpm. Examine the
formulation related to frictional heat, that needs to be cooled with the help of a cooling
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