Bayer HealthCare RapidPoint 400 Series, Руководство по обслуживанию

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Rev. C About Rapidpoint 400 Series Calibrations 427
About Rapidpoint 400 Series Calibrations
Overview
Calibration is the process of establishing a relationship between the
electronic signal from a sensor and known concentration of a calibration
solution. Electronic drift and normal sensor aging can cause variations in
electronic signals.
The relationship between the sensor signal and the concentration of a
measured analyte (or it’s logarithm) is linear. A straight line calibration
curve can be determined by measuring the sensor signal from two different
reagents of known concentration. Each measurement defines one point on
the calibration curve. The two points are used to calculate offset
(y-intercept) and slope. The measured signal of an unknown sample
(patient or QC) is used in conjunction with the slope and the offset to
calculate analyte concentration.
Calibration Types
There are three types of calibrations run on the Rapidpoint 400 series
system: 1-point, 2-point, and full 2-point.
A 1-point calibration (offsets for all analytes, except p O
2
, and glucose):
• A 1-point calibration adjusts either the offset or the slope drift for a
parameter by measuring one reagent of a known concentration.
• The system performs a 1-point calibration every 30 minutes.
• The system measures the 200 Cal calibrator on all sensors and the
system measures drift for all analytes. A 1-point calibration takes
2 minutes (2:00) to complete.
A 2-point calibration (offsets for all analytes and slope, except Hct):
• A 2-point calibration adjusts both the offset and the slope drift for a
parameter by measuring two reagents of known concentration.
• The system performs a 2-point calibration every 2 hours.