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Page 14  

37215 Instruction Manual (Rev. 4)

 

  

Start / Stop 

by pedal switch 

Power Requirement 

115/230 Volts, 50/60 Hz      

Reading 

index position on ruler, see paragraph 4.3-Reading the Results 

Force Range 

3 force ranges: 
37215 from 0 to 250, 500, 750 grams  
37216 from 0 to 125, 250, 375 grams  

Power Consumption 

15 W max. 

Connection to PC 

via 37215-100 Analgesy-Meter DAQ, see paragraphs 5-DATA 
ACQUISITION and 7.2-Optional 

Operating Temperature  10° to 40° C 
Sound Level  

negligible 

Physical 

 

Total Weight 

3.3 Kg 

Shipping Weight 

5.4 Kg approx. 

Dimensions 

46 x 16 x 14  cm 

Packing Dimensions 

55 x 45 x 36  cm 

Warranty 

 

Warranty 

367215 / 37216 are covered by a 24-month warranty. 

7.4 

BIBLIOGRAPHY 

7.5 

Method 

 

L.O. Randall and J.J. Selitto:

 “A Method for Measurement of Analgesic Ac-

tivity  on  Inflamed  Tissue

”  Arch.  Int.  Pharmacodyn.  CXI,  No.  4:  409-419, 

1957.

 

7.6 

Reference to UB Analgesy-Meter (Rat) 

 

E.K. Joseph et alia: “

Vascular Endothelial Cells Mediate Mechanical Stimu-

lation-Induced Enhancement of Endothelin Hyperalgesia via Activation of 
P2X

2/3 

Receptors on Nociceptors

” J. Neuroscience 33 (7): 2849-2859, 

2013

 

 

L. Ferrari et alia: “

Role of Nociceptor αCaMKII in Transition from Acute to 

Chronic Pain (Hyperalgesic Priming) in Male and Female Rats

” J. Neuro-

science 33 (27): 11002-11011, 

2013

 

 

H.J. Jeong et alia: “

Role of 5-HT

1

 

receptor subtypes in the modulation of 

pain and synaptic transmission in rat spinal superficial dorsal horn

” Br. J. 

Pharmacol. 165 (6): 1956-1965, 

2012

 

 

D.A.  Andersson  et  alia:  “

TRPA1  Has  a  Key  Role  in  the  Somatic  Pro-

Nociceptive Actions of Hydrogen Sulfide” 

PLoS ONE 7(10): e46917, 

2012

 

Summary of Contents for 37215

Page 1: ...ANALGESY METER ugobasile com Cat No 37215 Pain and Inflammation Instruction manual...

Page 2: ...the instrument in safe conditions Service and adjustments should be carried out by qualified personnel authorizedbyugobasileorganization Any adjustment maintenance and repair of the opened instrument...

Page 3: ...he Analgesy Meter in a fully digital device As the basic design is unchanged results with the digital model are consistent with published data The upgrade kit has been designed to be fitted on existin...

Page 4: ...M CM 458 F 1 37215 303 1 PEDAL SWITCH PEDALE E FT 001 1 2 FUSE T125mA FUSIBILE T125mA M LM 716 F 37216 323 2 ADDITIONAL DISC 37216 PESO AGGIUNTIVO 37216 M LM 446 37215 322 1 STANDARD PUSHER cone shap...

Page 5: ...ECTOR 5 3 3 3 MAINS CORD 5 3 4 CONNECTIONS 6 3 5 INTENDED USE 6 3 6 GENERAL SAFETY INSTRUCTIONS 6 3 7 ADDITIONAL SAFETY CONSIDERATION 6 3 8 NOTICE FOR THE CUSTOMERS IN JAPAN 7 4 OPERATION 7 4 1 PRELIM...

Page 6: ...D 14 7 6 REFERENCE TO UB ANALGESY METER RAT 14 7 7 REFERENCE TO UB ANALGESY METER MOUSE 15 FIGURE INDEX Figure 1 Front View 2 Figure 2 Back View 3 Figure 3 Back Panel 5 Figure 4 Analgesy Meter 37215 w...

Page 7: ...exerts a force increasing at a constant rate a certain number of grams per second This force is continuously monitored by a pointer moving along a linear scale The force is applied to the animal s pa...

Page 8: ...d mouse model 37216 is also available when lower pressure 50 is desirable The 37216 in cludes a specific slide and 50 reduced additional weights a standard and a chisel shaped pusher which make easier...

Page 9: ...d to increase the force on the paw at a rate of 16 grams per second 16x2 with one disc added 16x3 with two The rate at which the force increases has been found to be a satisfactory compromise for norm...

Page 10: ...there are not addi tional discs the calibrated weight of the slide includes the nut 3 INSTALLATION 3 1 Unpacking Preliminary Check Check the contents of the shipment for completeness packing list to h...

Page 11: ...itch This two pole toggle switch which complies with international safety standards provides a visual cue meaning OFF when pressed to the right O side ON when pressed to the left I side 3 3 2 Fuse Hol...

Page 12: ...oes not cause any circuit damage For connection to the optional Analgesy Meter DAQ 37215 100 please refer to the re lated instruction manual 3 5 Intended Use The Analgesy Meter is intended for investi...

Page 13: ...rent rate may impair the experiment consistency in particular if you compare the results gathered by two Analgesy Meters and one of them is fed by the wrong mains frequency In case of doubt ask for ad...

Page 14: ...hts 4 3 1 Standard Model 37215 Ruler 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 cm no weight 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 2...

Page 15: ...dels too For operation please refer to the 37215 100 specific manual Figure 5 Optional Pressure transducer Keep in mind that the readings obtained on the mechanical scale and those obtained by the ele...

Page 16: ...bearings are designed to operate mainte nance free DO NOT LUBRICATE 6 2 Electrical To inspect and or replace the fuses disconnect the mains cable first Insert a minia ture screwdriver in the slot ind...

Page 17: ...includes A specific slide A chisel shaped pusher Two 50 reduced additional weights The replacement is easily done following the steps indicated in the drawing below 1 slacken the two screws and the r...

Page 18: ...ile com Before sending any instrument to our factory for repair please contact our logistics department to obtain a return authorization number RMA and shipping packing instruc tions We may not be hel...

Page 19: ...5 324 Counterweight 10 complete with DELRIN set screw 37215 325 Slide Plastic Pad helical tooth which engages the driving screw NOTE Analgesy Meter is available for operation at 115 or 230 Volts 50 or...

Page 20: ...ethod L O Randall and J J Selitto A Method for Measurement of Analgesic Ac tivity on Inflamed Tissue Arch Int Pharmacodyn CXI No 4 409 419 1957 7 6 Reference to UB Analgesy Meter Rat E K Joseph et ali...

Page 21: ...9 7 7 Reference to UB Analgesy Meter Mouse K Sugimoto et alia The Impact of Low Dose Insulin on Peripheral Nerve Insulin Receptor Signaling in Streptozotocin Induced Diabetic Rats PLoS ONE 8 8 e74247...

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Page 24: ..._ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _...

Page 25: ...red in compliance with the following European Union Directives and relevant harmonized standards 2014 35 UE relating to electrical equipment designed for use within certain voltage limits 2014 30 UE r...

Page 26: ...sales ugobasile com Pain and Inflammation Ventilators and Gas Anesthesia Behaviour Conditioning Reward Behaviour Mazes Tracking Tissue baths Transducers Recorders Miscellaneous ECT LMD Blood Pressure...

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