6
•
Operation
Page 100
Diode Array/Multiple-Wavelength Detectors (VC-D11, VC-D12, VF-D11)
Operating Manual
•
Observe the general guidelines and recommendations on the use of
solvents and additives in the chromatography system. Refer to
Use
of Solvents and Additives
in the
Vanquish System Operating Manual
.
•
Degas the solvent.
•
Consider the influences of the parameters on the detection.
•
Keep the device doors closed and the flow cell cover installed during
operation to avoid exposure of the flow cell to thermal changes in
the environment that may lead to a baseline drift.
See also
2
Overview of Optimization Parameters (
6.7.2
Overview of Optimization Parameters
The following table serves as an overview of parameters that influence
the spectral averaging, and, in case of the data collection rate and the
response time, the time averaging during data acquisition.
TIP
Except for the slit width parameter, you can set the parameters shown
in the table below back to factory default values (see
Chromeleon Help
).
Parameter
Affects
Wavelength
Sensitivity, linearity
Data collection rate
Peak resolution, disk space
Bandwidth
Baseline noise, spectral resolution, peak match,
selectivity
Slit width (only available for
the VF detector)
Baseline noise, spectral resolution, peak match,
selectivity, linearity
Response time/peak width
Baseline noise, peak width, sensitivity
Bunch width (only available for
the VF‑D11 and VC‑D11
detectors)
Baseline noise, spectral resolution, peak match,
disk space
Reference wavelength
Baseline drift, baseline noise, linearity, negative
ghost peaks
Reference bandwidth
Baseline noise, baseline drift
Baseline behavior
Behavior of the baseline after switching the
wavelength.
For further information about the parameters, refer to the
Chromeleon
Help
.