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Running a protocol

Thermo Fisher Scientific

Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual

19

Click Loaded (or F6) to proceed.

When a cassette is required, a Cassette Load prompt is displayed,

indicating the type of cassette required.

Cassette prompt

and loading a

cassette

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Summary of Contents for Multidrop Pico 8

Page 1: ...Thermo Scientific Multidrop Pico 8 Digital Dispenser Operating Manual Cat no 1509040 Rev 01...

Page 2: ...ge without notice All technical information in this document is for reference purpose only System configurations and specifications in this document supersede all previous information received by the...

Page 3: ...tion Risk of injury to the user Risk of damage to the instrument other equipment or loss of performance or function in a specific application Note Marks a tip important information that is useful in t...

Page 4: ......

Page 5: ...isposal of cassettes and pipette tips 11 Ergonomic safety 11 Additional assistance 11 System specifications 12 Intended use 12 Hardware 12 Environmental operating conditions 12 Shipping and storage co...

Page 6: ...ges 26 Cassette changes 26 Preventative maintenance procedures 27 Turning off the Multidrop Pico dispenser 27 Cleaning the Multidrop Pico dispenser 28 Pogo pin inspection 29 Pogo pin cleaning 30 A1 al...

Page 7: ...ontact digital dispensing in the picoliter to microliter range It combines walk up convenience ready to run performance and flexible intuitive experiment design software to increase research productiv...

Page 8: ...complete set ups even for the most complex experiments such as drug drug co titration or enzyme kinetic studies in minutes Achieve excellent data resolution 0 02 Log Increments Capable of digitally r...

Page 9: ...andard grounded electrical outlet Note the power requirement listed on the back label of the Multidrop Pico dispenser Avoid the moving parts of the Multidrop Pico dispenser during operation The safety...

Page 10: ...rference that may cause undesired operation Any changes or modifications to this equipment not expressly approved by Thermo Fisher Scientific may cause harmful interference and it would void your warr...

Page 11: ...ater shoulder elevation when pipetting into the cassette and having the Multidrop Pico dispenser too low can lead to increased neck and back flexion If an operator is too short to comfortably access t...

Page 12: ...s in Bio Safety Level 3 or 4 BSL 3 or 4 food animal or human testing or therapeutic delivery except solely for therapeutic delivery for in vitro research uses b dispensing cells biofluids unless other...

Page 13: ...ia are compatible with the Multidrop Pico dispenser One of the following types 12 24 48 96 384 1536 well format Meet ANSI specifications for footprint dimensions and well locations if applicable Betwe...

Page 14: ...ower and USB connections 9 PC with Multidrop Pico dispenser software The Multidrop Pico dispenser runs on standard AC power between 100 240V Warning Be sure the Multidrop Pico dispenser power requirem...

Page 15: ...arning Do not place items heavier than 2 5 kg 5 lbs on the top surface of the Multidrop Pico dispenser Unpack the Multidrop Pico dispenser and remove the four pieces of the shipping bracket Connect th...

Page 16: ...ing the run In simulation mode the Simulation Speed bar is displayed Use the bar to adjust the progress speed of the dynamic display of fluids as they are being dispensed You can adjust the simulation...

Page 17: ...ensing is occurring After you click Pause Abort click Resume to proceed with the just paused run below left or Abort to terminate it When appropriate additional options will be offered Show Plate will...

Page 18: ...ification number manually into the Plate ID optional field Note If Require and validate plate ID option has been selected in Run Settings you must enter a Plate ID and re enter that ID each time the p...

Page 19: ...hermo Scientific Multidrop Pico 8 Digital Dispense Operating Manual 19 Click Loaded or F6 to proceed When a cassette is required a Cassette Load prompt is displayed indicating the type of cassette req...

Page 20: ...ound the cassette Once you have confirmed that the cassette has been loaded click Loaded or F3 Note If the cassette has an identification code you would like to track scan or enter its identification...

Page 21: ...ble dispensehead you can click Skip Skipping a dispensehead shifts down by one dispensehead all the fluids in the list that have not yet been loaded A skipped dispensehead should usually be marked as...

Page 22: ...nse volume and fluid class with greater dispense volumes and certain classes of fluids having greater dead volumes The minimum load volume ensures proper priming of the cassettes see Appendix E Dispen...

Page 23: ...umber of fluids in the proper order as shown in the Load Fluid prompt Load fluid into the cassette position indicated in the Load Fluid prompt when prompted This dispensehead location will be indicate...

Page 24: ...o Fisher Scientific Blue LED illuminates the dispensehead in the cassette Pipette directly into the opening Examples of good and bad load Note Make sure to load the fluid into the opening on top of th...

Page 25: ...om spilling out of the reservoir Pipette directly into the opening Good load Bad load Examples of good and bad load Beneath the Load Fluid prompt a Help panel illustrates the best practice for loading...

Page 26: ...fluids on the current plate The current dispense plate if shown at the right along with the next dispense plate Note that the next dispense plate is only indicated for fluids dispensed from the curren...

Page 27: ...be accessed from the File Documentation menu in the Multidrop Pico dispenser software Once you have finished using the Multidrop Pico dispenser and will not use it again for an extended period of time...

Page 28: ...clicking Exit in the File Menu Turn off the Multidrop Pico dispenser and remove the power and USB cables from the back of the Multidrop Pico dispenser Remove any unused cassettes from the Multidrop P...

Page 29: ...ultidrop Pico dispenser Close the Multidrop Pico dispenser software either by clicking the X in the upper right corner of the main operating window or by clicking Exit in the File Menu Turn off the Mu...

Page 30: ...he deck Inspect the pogo pins from the front and side to ensure that all 48 pogo pins are not bent and extend fully Very gently in order to not to bend the pogo pins wipe the pogo pins with a non fibr...

Page 31: ...o test alignment Please use this section only if you are comfortable with resetting computer parameters for instruments such as the Multidrop Pico dispenser If you are unsure about this procedure at a...

Page 32: ...ey will be validated If necessary you will be prompted again for cassette and or plate load DMSO or an aqueous fluid with surfactant can be used for dispensing Colorant not more than 10 food coloring...

Page 33: ...id in any one corner is off by more than 1 0 mm in a different direction than the other corners the stage assembly is not square and you need to contact the Service Help Desk The contact information c...

Page 34: ...strument Building Floor Room Multidrop Pico dispenser Software Version Preventative Maintenance Procedures NA Done Cleaning the Instrument Pogo Pin Inspection Pogo Pin Cleaning A1 Alignment Check A1 R...

Page 35: ...oes not contain any of the RoHS materials above the applicable threshold levels and is therefore eligible for the China RoHS e label T rkiye Cumhuriyeti AEEE Y netmeli ine Uygundur English meaning Rep...

Page 36: ...e Gesundheit des Menschen und der Umwelt darstellt Weitere Informationen dar ber wo Sie alte Elektroger te zum Recyceln abgeben k nnen erhalten Sie bei den rtlichen Beh rden Wertstoffh fen oder dort w...

Page 37: ...lt gy jt helyre amely az elektromos hullad kanyagok s az elektronikus berendez sek jrahasznos t s val foglalkozik A hullad kanyagok elk l n tett gy jt se s jrahasznos t sa hozz j rul a term szeti er...

Page 38: ...e chr ni pr rodn zdroje a zabezpe tak sp sob recykl cie ktor bude chr ni udsk zdravie a ivotn prostredie al ie inform cie o separovanom zbere a recykl cii z skate na miestnom obecnom rade vo firme za...

Page 39: ...entific Multidrop Pico 8 Digital Dispense Operating Manual 39 Pb Hg Cd Cr VI PBB PBDE O O O O O O O O O O O O O O O O O O X O O O O O O O O O O O CD O O O O O O O O O O O O X O O O O O X O O O O O O O...

Page 40: ...Information Products Part Name Hazardous Substances Lead Pb Mercury Hg Cadmium Cd Hexavalent Chromium Cr VI Polybrominated biphenyls PBB Polybrominated diphenyl ethers PBDE Cable Wiring O O O O O O Ch...

Page 41: ...als in the component is within the limits required by GB T 26572 X Indicates that the content of said hazardous substance exceeds the limits required by GB T 26572 in at least one homogenous material...

Page 42: ...ThermoFisher Scientific Thermo Scientific Dispenser Operating Manual Subject 42...

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