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When cleaning other components (for example, the injector, the autosampler, or
detector cells) in addition to the pump, use acid when an alkaline solution has been
determined to be more effective, except. The acid (nitric acid) and alkaline solution
(sodium hydroxide) concentrations described above are also used in cleaning other
components.
CAUTION: The valve rotor seals (polyimide resin) used by the injector and
autosampler, as well as detector cells (quartz glass cells), cannot
withstand prolonged contact with alkaline solutions.
4.3.3 Cleaning procedure
A general outline of cleaning procedures is shown below (Refer to Fig. 4.5 for
details).
(1) Replace the solvent in the pump with water.
(2) Perform the pressure test and verify that there are no leaks.
(3) Flush with acid (or an alkaline solution).
(4) Replace the solvent inside the pump with water.
(5) Replace the water inside the pump with methanol.
(6) Repeat Steps (4) and (5).
(7) Restore the original solvent.
WARNING
: Wear a protective mask and rubber gloves and exercise due caution
when handling acids or alkaline solutions.