5
Table 2.2 Dealing with TROUBLE UNDER PRESS errors
Cause Confirmation
Method
What to Do
Pump head contains air
bubbles
Open the purge valve and
remove the air bubbles (See
Section 4.1)
Inlet filter is clogged (use of
buffer solutions often leads
to clogging)
Check for
clogging
(See Section
5.3)
Replace the inlet filter
Plunger seal is leaking
Tighten the pump head
securing screws (See Section
2.4.1)
If the leaking continues,
replace the plunger seal (See
Section 5.1)
Inlet tube fitting is leaking
Tighten the fitting
(See Section 2.4.6)
Leak at downstream side of
pump (manual injector,
autosampler, column, fitting,
etc.)
Refer to the appropriate
manual
Pump head deterioration
Perform
pressure tests
(See Section
3.1)
Clean the pump head
thoroughly using an acid or
alkaline solution
(See Section 4.3)
2.1.3 Large variations in operating pressure
Table 2.3 lists potential causes, confirmation methods, and methods for solving
problems that may arise due to large variations in operating pressure.