Document No. 715-7000
Revision E
Page 45 of 63
SECTION VI - NITRIC OXIDE DELIVERY
The AeroNOx
Nitric Oxide Titration & Monitoring System was designed to deliver a continuous
flow of NO gas into the patient’s bulk gas flow.
Inspiratory Limb NO Titration in Constant Flow Ventilators or Other Respiratory Gas
Administration Systems
This technique is modeled after the system tested by Betit and colleagues published in
Respiratory Care
July 1995 Vol 40 No. 7 p 706-715.
With constant flow ventilators, stability of
the [NO] is assured because both the NO gas and the gas flow from the ventilator are fixed
(constant).
Precautions for Inspiratory Limb NO Titration
1.
Carefully select “tight” NO & NO
2
alarms on the NO / NO
2
analyzer.
2.
Where applicable, ensure that the minute ventilation supplied by the ventilator or by other
respiratory gas administration systems is consistent. Carefully select “tight” minute
volume alarms. This is critical.
3.
Titrate the desired NO dose before you attach the system to the patient, using a test lung
with both the ventilator & NO delivery system running for approximately 1 minute prior to
patient connection.
4.
Ensure that the dose measured by the AeroNOx
is the actual desired nitric oxide
concentration and that NO
2
values are acceptable. For acceptable limits, see the “NO
2
in
ppm” table in SECTION VII.
Ventilators Safe for Use with the AeroNOx
In general, any ventilator which functions as a true continuous flow ventilator may be used with
the AeroNOx
. Some ventilators have modes labeled “continuous flow” but may not function as
true continuous flow ventilators. Please consult the manufacturer of the ventilator you intend to
use with the AeroNOx
to determine if, and in what modes, your ventilator will operate as a
continuous flow ventilator.
CAUTION!
The AeroNOx
is designed to be used with continuous flow ventilators
only! Check with your ventilator manufacturer to determine the flow
characteristics of the ventilator you wish to use.
The following ventilators have been tested for use with the AeroNOx
:
1. Sechrist
100IVB
in all modes
2. Bird
VIP
in conjunction with the Infant Flow Sensor
in the following time cycled modes:
a) Assist
Control
b) SIMV
c) CPAP
3.
Infant Star 100 Neonatal Ventilator
4. SensorMedics
3100A
& 3100B
5. BioMed
Devices
MVP-10 Ventilator
6.
BioMed Devices CV2i Ventilator
7.
Percussionaire Bronchotron Ventilator